US5795870A
(en)
*
|
1991-12-13 |
1998-08-18 |
Trustees Of Princeton University |
Compositions and methods for cell transformation
|
US5693769A
(en)
*
|
1991-12-13 |
1997-12-02 |
Transcell Technologies, Inc. |
Glycosylated steroid derivatives for transport across biological membranes and process for making and using same
|
US5792751A
(en)
*
|
1992-04-13 |
1998-08-11 |
Baylor College Of Medicine |
Tranformation of cells associated with fluid spaces
|
DE69407292T2
(en)
*
|
1993-06-30 |
1998-06-25 |
Genentech Inc |
METHOD FOR PRODUCING LIPOSOME
|
JPH10506396A
(en)
*
|
1994-10-03 |
1998-06-23 |
ジェ. ベルジュロン,ミシェル |
Methods and formulations for treating AIDS and some other viral diseases
|
GB9519654D0
(en)
*
|
1995-09-27 |
1995-11-29 |
Nycomed Imaging As |
Stabilised phospholipid compositions
|
US5734040A
(en)
*
|
1996-03-21 |
1998-03-31 |
University Of Iowa Research Foundation |
Positively charged oligonucleotides as regulators of gene expression
|
US6274313B1
(en)
|
1996-03-21 |
2001-08-14 |
Pioneer-Hybrid International, Inc. |
Oligonucleotides with cationic phosphoramidate internucleoside linkages and methods of use
|
US6331617B1
(en)
|
1996-03-21 |
2001-12-18 |
University Of Iowa Research Foundation |
Positively charged oligonucleotides as regulators of gene expression
|
AU3514197A
(en)
|
1996-07-03 |
1998-01-21 |
Genetics Institute Inc. |
Protease fmh-1, an ice/ced-like protease
|
US6211162B1
(en)
*
|
1998-12-30 |
2001-04-03 |
Oligos Etc. Inc. |
Pulmonary delivery of protonated/acidified nucleic acids
|
US6211349B1
(en)
*
|
1998-12-30 |
2001-04-03 |
Oligos Etc., Inc. |
Protonated/acidified nucleic acids and methods of use
|
US20020032164A1
(en)
|
1998-12-30 |
2002-03-14 |
Dale Roderic M. K. |
Antimicrobial compounds and methods for their use
|
US7868162B2
(en)
|
1998-12-30 |
2011-01-11 |
Lakewood-Amedex, Inc. |
Antimicrobial and antiviral compounds and methods for their use
|
US6627215B1
(en)
|
1998-12-30 |
2003-09-30 |
Oligos Etc. Inc. |
Devices for improved wound management
|
IL159722A0
(en)
|
2001-07-10 |
2004-06-20 |
Oligos Etc Inc |
Pharmaceutical compositions containing oligonucleotides
|
US20060009409A1
(en)
|
2002-02-01 |
2006-01-12 |
Woolf Tod M |
Double-stranded oligonucleotides
|
ATE529512T1
(en)
|
2002-02-01 |
2011-11-15 |
Life Technologies Corp |
DOUBLE STRANDED OLIGONUCLEOTIDES
|
KR101376895B1
(en)
|
2004-05-03 |
2014-03-25 |
헤르메스 바이오사이언스, 인코포레이티드 |
Liposomes useful for drug delivery
|
US8658203B2
(en)
|
2004-05-03 |
2014-02-25 |
Merrimack Pharmaceuticals, Inc. |
Liposomes useful for drug delivery to the brain
|
WO2006042112A2
(en)
|
2004-10-05 |
2006-04-20 |
California Institute Of Technology |
Aptamer regulated nucleic acids and uses thereof
|
CA2610791C
(en)
|
2005-06-08 |
2015-12-01 |
Cangene Corporation |
Hyaluronic acid binding peptides enhance host defense against pathogenic bacteria
|
EP2980220A1
(en)
|
2005-09-20 |
2016-02-03 |
BASF Plant Science GmbH |
Improved methods controlling gene expression
|
WO2008058291A2
(en)
|
2006-11-09 |
2008-05-15 |
California Institute Of Technology |
Modular aptamer-regulated ribozymes
|
US8367815B2
(en)
|
2007-08-28 |
2013-02-05 |
California Institute Of Technology |
Modular polynucleotides for ligand-controlled regulatory systems
|
US20120165387A1
(en)
|
2007-08-28 |
2012-06-28 |
Smolke Christina D |
General composition framework for ligand-controlled RNA regulatory systems
|
US8865667B2
(en)
|
2007-09-12 |
2014-10-21 |
California Institute Of Technology |
Higher-order cellular information processing devices
|
US9029524B2
(en)
|
2007-12-10 |
2015-05-12 |
California Institute Of Technology |
Signal activated RNA interference
|
CN104975020B
(en)
|
2008-02-11 |
2020-01-17 |
菲奥医药公司 |
Modified RNAi polynucleotides and uses thereof
|
WO2010008582A2
(en)
|
2008-07-18 |
2010-01-21 |
Rxi Pharmaceuticals Corporation |
Phagocytic cell drug delivery system
|
JP6209309B2
(en)
|
2008-09-22 |
2017-10-04 |
アールエックスアイ ファーマシューティカルズ コーポレーション |
Reduced size RNAi compound for self delivery
|
US9074211B2
(en)
|
2008-11-19 |
2015-07-07 |
Rxi Pharmaceuticals Corporation |
Inhibition of MAP4K4 through RNAI
|
US9493774B2
(en)
|
2009-01-05 |
2016-11-15 |
Rxi Pharmaceuticals Corporation |
Inhibition of PCSK9 through RNAi
|
WO2010090762A1
(en)
|
2009-02-04 |
2010-08-12 |
Rxi Pharmaceuticals Corporation |
Rna duplexes with single stranded phosphorothioate nucleotide regions for additional functionality
|
US8329882B2
(en)
|
2009-02-18 |
2012-12-11 |
California Institute Of Technology |
Genetic control of mammalian cells with synthetic RNA regulatory systems
|
US9145555B2
(en)
|
2009-04-02 |
2015-09-29 |
California Institute Of Technology |
Integrated—ligand-responsive microRNAs
|
US9340786B2
(en)
|
2010-03-24 |
2016-05-17 |
Rxi Pharmaceuticals Corporation |
RNA interference in dermal and fibrotic indications
|
EP3578183B1
(en)
|
2010-03-24 |
2021-09-08 |
Phio Pharmaceuticals Corp. |
Rna interference in ocular indications
|
WO2015085113A1
(en)
|
2013-12-04 |
2015-06-11 |
Rxi Pharmaceuticals Corporation |
Methods for treatment of wound healing utilizing chemically modified oligonucleotides
|
CA2947270A1
(en)
|
2014-04-28 |
2015-11-05 |
Rxi Pharmaceuticals Corporation |
Methods for treating cancer using nucleic acids targeting mdm2 or mycn
|
US20170051290A1
(en)
|
2014-05-01 |
2017-02-23 |
Rxi Pharmaceuticals Corporation |
Methods for treatment of disorders in the front of the eye utilizing nucleic acid molecules
|
CN107073294A
(en)
|
2014-09-05 |
2017-08-18 |
阿克赛医药公司 |
Use the method for targeting TYR or MMP1 exonuclease treatment aging and skin disorder
|
WO2017007825A1
(en)
|
2015-07-06 |
2017-01-12 |
Rxi Pharmaceuticals Corporation |
Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach
|
EP3319614B1
(en)
|
2015-07-06 |
2020-12-23 |
Phio Pharmaceuticals Corp. |
Nucleic acid molecules targeting superoxide dismutase 1 (sod1)
|
CA3001467A1
(en)
|
2015-10-16 |
2017-04-20 |
Ipsen Biopharm Ltd. |
Stabilizing camptothecin pharmaceutical compositions
|
CA3002744A1
(en)
|
2015-10-19 |
2017-04-27 |
Rxi Pharmaceuticals Corporation |
Reduced size self-delivering nucleic acid compounds targeting long non-coding rna
|
US11795192B2
(en)
|
2017-03-10 |
2023-10-24 |
Lakewood Amedex, Inc. |
Antimicrobial compounds, compositions, and uses thereof
|
CR20200251A
(en)
|
2017-11-17 |
2020-07-17 |
Iovance Biotherapeutics Inc |
Til expansion from fine needle aspirates and small biopsies
|
JP2021503885A
(en)
|
2017-11-22 |
2021-02-15 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
Expanded culture of peripheral blood lymphocytes (PBL) from peripheral blood
|
EP3737743A1
(en)
|
2018-01-08 |
2020-11-18 |
Iovance Biotherapeutics, Inc. |
Processes for generating til products enriched for tumor antigen-specific t-cells
|
US11713446B2
(en)
|
2018-01-08 |
2023-08-01 |
Iovance Biotherapeutics, Inc. |
Processes for generating TIL products enriched for tumor antigen-specific T-cells
|
WO2019136459A1
(en)
|
2018-01-08 |
2019-07-11 |
Iovance Biotherapeutics, Inc. |
Processes for generating til products enriched for tumor antigen-specific t-cells
|
JP2022512899A
(en)
|
2018-11-05 |
2022-02-07 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
Treatment of NSCLC patients refractory to anti-PD-1 antibody
|
TW202039829A
(en)
|
2018-11-05 |
2020-11-01 |
美商艾歐凡斯生物治療公司 |
Selection of improved tumor reactive t-cells
|
MX2021005216A
(en)
|
2018-11-05 |
2021-06-18 |
Iovance Biotherapeutics Inc |
Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy.
|
CA3118493A1
(en)
|
2018-11-05 |
2020-05-14 |
Iovance Biotherapeutics, Inc. |
Expansion of tils utilizing akt pathway inhibitors
|
EP3898949A1
(en)
|
2018-12-19 |
2021-10-27 |
Iovance Biotherapeutics, Inc. |
Methods of expanding tumor infiltrating lymphocytes using engineered cytokine receptor pairs and uses thereof
|
US20220133795A1
(en)
|
2019-03-01 |
2022-05-05 |
Iovance Biotherapeutics, Inc. |
Expansion of Tumor Infiltrating Lymphocytes From Liquid Tumors and Therapeutic Uses Thereof
|
US20220249559A1
(en)
|
2019-05-13 |
2022-08-11 |
Iovance Biotherapeutics, Inc. |
Methods and compositions for selecting tumor infiltrating lymphocytes and uses of the same in immunotherapy
|
US20230002766A1
(en)
|
2019-11-08 |
2023-01-05 |
Phio Pharmaceuticals Corp. |
Chemically modified oligonucleotides targeting bromodomain containing protein 4 (brd4) for immunotherapy
|
WO2021118990A1
(en)
|
2019-12-11 |
2021-06-17 |
Iovance Biotherapeutics, Inc. |
Processes for the production of tumor infiltrating lymphocytes (tils) and methods of using the same
|
EP4085136A1
(en)
|
2019-12-31 |
2022-11-09 |
Phio Pharmaceuticals Corp. |
Chemically modified oligonucleotides with improved systemic delivery
|
EP4146794A1
(en)
|
2020-05-04 |
2023-03-15 |
Iovance Biotherapeutics, Inc. |
Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy
|
WO2023015264A1
(en)
|
2021-08-04 |
2023-02-09 |
Phio Pharmaceuticals Corp. |
Immunotherapy of cancer utilizing natural killer cells treated with chemically modified oligonucleotides
|
KR20240041973A
(en)
|
2021-08-04 |
2024-04-01 |
피오 파마슈티칼스 코프. |
Chemically modified oligonucleotides
|
WO2024098024A1
(en)
|
2022-11-04 |
2024-05-10 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|