CN101490249A - 提高平衡反应的产量的方法和系统 - Google Patents
提高平衡反应的产量的方法和系统 Download PDFInfo
- Publication number
- CN101490249A CN101490249A CNA200780027087XA CN200780027087A CN101490249A CN 101490249 A CN101490249 A CN 101490249A CN A200780027087X A CNA200780027087X A CN A200780027087XA CN 200780027087 A CN200780027087 A CN 200780027087A CN 101490249 A CN101490249 A CN 101490249A
- Authority
- CN
- China
- Prior art keywords
- reaction
- booth
- product
- enzyme
- promotor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/34—Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/362—Cation-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/363—Anion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3804—Affinity chromatography
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Indole Compounds (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80310506P | 2006-05-24 | 2006-05-24 | |
| US60/803,105 | 2006-05-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101490249A true CN101490249A (zh) | 2009-07-22 |
Family
ID=38779330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA200780027087XA Pending CN101490249A (zh) | 2006-05-24 | 2007-05-23 | 提高平衡反应的产量的方法和系统 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7888081B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2038405A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2009538145A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101490249A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007267618B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0711972A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2653054A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2007140195A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7297800B2 (en) | 2001-12-27 | 2007-11-20 | Ajinomoto Co., Inc. | Process of producing glutamate derivatives |
| US7572607B2 (en) * | 2002-04-23 | 2009-08-11 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
| US8372989B2 (en) * | 2002-04-23 | 2013-02-12 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
| CA2714881C (en) | 2002-08-26 | 2012-10-23 | Ajinomoto Co., Inc. | Novel aldolase and production process of substituted .alpha.-keto acids |
| KR100723826B1 (ko) | 2002-12-09 | 2007-06-04 | 아지노모토 가부시키가이샤 | 변이형 d-아미노트랜스퍼라제 및 이를 사용하는 광학활성글루탐산 유도체의 제조방법 |
| US7556660B2 (en) * | 2003-06-11 | 2009-07-07 | James Kevin Shurtleff | Apparatus and system for promoting a substantially complete reaction of an anhydrous hydride reactant |
| WO2005014839A2 (en) * | 2003-08-01 | 2005-02-17 | Cargill, Incorporated | Monatin tabletop sweetener compositions and methods of making same |
| DE602004006141T2 (de) * | 2003-08-14 | 2007-12-27 | Cargill, Inc., Wayzata | Monatinhaltige kaugummizusammensetzungen und verfahren zu ihrer herstellung |
| JP2007503214A (ja) * | 2003-08-25 | 2007-02-22 | カーギル,インコーポレイティド | モナチンを含む飲料組成物及びその製造方法 |
| US8206955B2 (en) * | 2003-10-21 | 2012-06-26 | Cargill, Incorporated | Production of monatin and monatin precursors |
| US8158389B2 (en) * | 2005-04-20 | 2012-04-17 | Cargill, Incorporated | Products and methods for in vivo secretion of monatin |
| CN101223444B (zh) * | 2005-04-20 | 2013-04-24 | 嘉吉有限公司 | 在体内分泌莫纳甜的方法 |
| US7582455B2 (en) * | 2005-04-26 | 2009-09-01 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
| US8076108B2 (en) * | 2005-04-26 | 2011-12-13 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
| US20080020260A1 (en) * | 2005-11-12 | 2008-01-24 | Brydon Chris A | Apparatus, system, and method for manifolded integration of a humidification chamber for input gas for a proton exchange membrane fuel cell |
| WO2007103389A2 (en) * | 2006-03-07 | 2007-09-13 | Cargill, Incorporated | Aldolases, nucleic acids encoding them and methods for making and using them |
| US20090198072A1 (en) * | 2006-05-24 | 2009-08-06 | Cargill, Incorporated | Methods and systems for increasing production of equilibrium reactions |
| US7648786B2 (en) | 2006-07-27 | 2010-01-19 | Trulite, Inc | System for generating electricity from a chemical hydride |
| US7651542B2 (en) | 2006-07-27 | 2010-01-26 | Thulite, Inc | System for generating hydrogen from a chemical hydride |
| US8357214B2 (en) | 2007-04-26 | 2013-01-22 | Trulite, Inc. | Apparatus, system, and method for generating a gas from solid reactant pouches |
| US20090025293A1 (en) * | 2007-07-25 | 2009-01-29 | John Patton | Apparatus, system, and method for processing hydrogen gas |
| KR20100061453A (ko) | 2007-07-25 | 2010-06-07 | 트루라이트 인크. | 하이브리드 전력의 생성 및 사용을 관리하는 장치, 시스템 및 방법 |
| US8076107B2 (en) | 2007-10-01 | 2011-12-13 | Cargill, Incorporated | Production of monatin stereoisomers |
| US8003361B2 (en) * | 2007-10-01 | 2011-08-23 | Cargill Incorporated | Production of monatin enantiomers |
| US8367847B2 (en) * | 2007-10-01 | 2013-02-05 | Cargill, Incorporated | Production of monatin enantiomers |
| DK2238242T5 (en) * | 2008-01-03 | 2015-08-03 | Basf Enzymes Llc | -Transferases and oxidoreductases, nucleic acids encoding FOR THEM, AND PROCESSES FOR THE STILL LING AND USE THEREOF |
| WO2009088482A1 (en) | 2008-01-03 | 2009-07-16 | Cargill, Incorporated | Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of using |
| US8857279B2 (en) * | 2008-03-03 | 2014-10-14 | William P. Hanson | Analyte screening and detection systems and methods |
| US20120322906A1 (en) * | 2009-12-30 | 2012-12-20 | Cargill, Incorporated | Polymer and methods of preparing and using a polymer |
| WO2011082363A1 (en) * | 2009-12-30 | 2011-07-07 | Cargill, Incorporated | Membrane separation and purification of monatin |
| WO2011082353A1 (en) * | 2009-12-30 | 2011-07-07 | Cargill, Incorporated | Separation and purification of monatin |
| WO2012166406A1 (en) * | 2011-05-31 | 2012-12-06 | Cargill, Incorporated | Increasing product yield and/or throughput by supersaturation of substrate |
| EP2909327A1 (en) * | 2012-10-18 | 2015-08-26 | Sandoz AG | A process for preparing indoline derivatives |
| MX2016016335A (es) | 2014-06-13 | 2017-07-20 | Proslide Technology Inc | Atraccion acuatica. |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3002889A (en) | 1960-06-20 | 1961-10-03 | Kyowa Hakko Kogyo Kk | Method of producing l-glutamic acid |
| US3751458A (en) | 1972-03-02 | 1973-08-07 | Miles Lab | Citroylformic acid and its production |
| US4010204A (en) | 1974-04-09 | 1977-03-01 | Studiengesellschaft Kohle M.B.H. | Process for preparing condensation products |
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| GB2205834B (en) | 1987-06-15 | 1990-10-31 | South African Inventions | 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl)-indole compounds |
| WO1989011212A2 (en) | 1989-08-30 | 1989-11-30 | Wm. Wrigley Jr. Company | Method of controlling release of cyclamate in chewing gum and gum produced thereby |
| EP0438314B1 (en) | 1990-01-19 | 1994-04-27 | Technology Finance Corporation (Proprietary) Limited | Process for the production of 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl) indole |
| US6264999B1 (en) | 1993-09-30 | 2001-07-24 | Wm. Wrigley Jr. Company | Chewing gum containing erythritol and method of making |
| JP3698742B2 (ja) | 1994-03-01 | 2005-09-21 | 協和醗酵工業株式会社 | 光学活性4−ヒドロキシ−2−ケトグルタル酸の製造法 |
| US5728555A (en) | 1996-09-30 | 1998-03-17 | Monsanto Company | Preparation of d-amino acids by direct fermentative means |
| US5994559A (en) | 1998-08-06 | 1999-11-30 | The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations | Synthesis of monatin-A high intensity natural sweetener |
| JP2002060382A (ja) | 2000-08-22 | 2002-02-26 | Ajinomoto Co Inc | モナティンの立体異性体及びその使用、並びにモナティン類の製造方法及びそのための中間体 |
| KR100949049B1 (ko) | 2001-11-30 | 2010-03-25 | 아지노모토 가부시키가이샤 | 모나틴의 비천연형 입체이성체 염의 결정 및 이의 사용 |
| JP2003171365A (ja) | 2001-11-30 | 2003-06-20 | Ajinomoto Co Inc | モナティン類及びその製造中間体の製造方法並びに新規中間体 |
| EP1445323B1 (en) | 2001-12-27 | 2011-01-26 | Ajinomoto Co., Inc. | Process for producing glutamic acid derivatives |
| ATE552242T1 (de) | 2001-12-27 | 2012-04-15 | Ajinomoto Kk | ßVERFAHREN ZUR HERSTELLUNG VON GLUTAMINSÄUREVERBINDUNGEN UND ZWISCHENPRODUKTEN DAVON, UND IN DEN VERFAHREN VERWENDETE NEUE ZWISCHENPRODUKTEß |
| US7297800B2 (en) | 2001-12-27 | 2007-11-20 | Ajinomoto Co., Inc. | Process of producing glutamate derivatives |
| JP2003292484A (ja) | 2002-04-01 | 2003-10-15 | Ajinomoto Co Inc | γ−ヒドロキシアミノ酸誘導体及びモナティン類の製造方法 |
| WO2003091396A2 (en) | 2002-04-23 | 2003-11-06 | Cargill, Incorporated | Polypeptides and biosynthetic pathways |
| US7572607B2 (en) | 2002-04-23 | 2009-08-11 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
| US8372989B2 (en) | 2002-04-23 | 2013-02-12 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
| CA2714881C (en) | 2002-08-26 | 2012-10-23 | Ajinomoto Co., Inc. | Novel aldolase and production process of substituted .alpha.-keto acids |
| KR100723826B1 (ko) | 2002-12-09 | 2007-06-04 | 아지노모토 가부시키가이샤 | 변이형 d-아미노트랜스퍼라제 및 이를 사용하는 광학활성글루탐산 유도체의 제조방법 |
| ATE522497T1 (de) | 2003-01-09 | 2011-09-15 | Ajinomoto Kk | Verfahren zur herstellung eines glutaminsäurederivats, ein pyroglutaminsäurederivat und ein neues zwischenprodukt für die herstellung |
| JP4239600B2 (ja) | 2003-01-24 | 2009-03-18 | 味の素株式会社 | 2r−モナティンの製造方法 |
| JP2004331650A (ja) | 2003-04-14 | 2004-11-25 | Kanazawa Univ Tlo Inc | モナチン類の製造法 |
| JP2004331644A (ja) | 2003-04-14 | 2004-11-25 | Kanazawa Univ Tlo Inc | モナチン類の製造法 |
| WO2005001105A1 (ja) | 2003-06-26 | 2005-01-06 | Ajinomoto Co., Inc. | モナティンの製造方法 |
| WO2005014839A2 (en) | 2003-08-01 | 2005-02-17 | Cargill, Incorporated | Monatin tabletop sweetener compositions and methods of making same |
| DE602004006141T2 (de) | 2003-08-14 | 2007-12-27 | Cargill, Inc., Wayzata | Monatinhaltige kaugummizusammensetzungen und verfahren zu ihrer herstellung |
| JP2007503214A (ja) | 2003-08-25 | 2007-02-22 | カーギル,インコーポレイティド | モナチンを含む飲料組成物及びその製造方法 |
| US8206955B2 (en) | 2003-10-21 | 2012-06-26 | Cargill, Incorporated | Production of monatin and monatin precursors |
| JP4500977B2 (ja) | 2003-11-05 | 2010-07-14 | 味の素株式会社 | 新規アミノ酸誘導体及び甘味剤 |
| JP5113978B2 (ja) | 2003-11-21 | 2013-01-09 | 味の素株式会社 | グルタミン酸誘導体の有機アミン塩及びその利用 |
| KR101070183B1 (ko) | 2004-02-27 | 2011-10-05 | 아지노모토 가부시키가이샤 | 모나틴의 제조방법 |
| JP4604524B2 (ja) | 2004-03-16 | 2011-01-05 | 味の素株式会社 | 変異型アルドラーゼ、並びにこれを用いた光学活性ihog及び光学活性モナティンの製造方法 |
| JP4604537B2 (ja) | 2004-03-31 | 2011-01-05 | 味の素株式会社 | L−システイン生産菌及びl−システインの製造法 |
| US7935377B2 (en) | 2004-06-04 | 2011-05-03 | Ajinomoto Co., Inc. | Crystals of free (2R, 4R)-monatin and use thereof |
| CA2506247C (en) | 2004-06-07 | 2012-02-21 | Ajinomoto Co., Inc. | Novel aldolase, and method for producing optically active ihog and monatin |
| KR101216575B1 (ko) | 2004-07-14 | 2012-12-31 | 아지노모토 가부시키가이샤 | (2r,4r)-모나틴 칼륨 염 결정 및 이를 함유하는 감미료조성물 |
| JP2007284349A (ja) | 2004-07-27 | 2007-11-01 | Ajinomoto Co Inc | モナティンまたはその塩の製造方法 |
| WO2006041216A1 (ja) | 2004-10-15 | 2006-04-20 | Ajinomoto Co., Inc. | 甘味料組成物 |
| US7923231B2 (en) | 2004-12-17 | 2011-04-12 | Cargill, Incorporated | Production of glucuronic acid using myo-inositol oxygenase from cryptococcus neoformans |
| CN101223444B (zh) | 2005-04-20 | 2013-04-24 | 嘉吉有限公司 | 在体内分泌莫纳甜的方法 |
| US8158389B2 (en) | 2005-04-20 | 2012-04-17 | Cargill, Incorporated | Products and methods for in vivo secretion of monatin |
| US7582455B2 (en) | 2005-04-26 | 2009-09-01 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
| BRPI0609876A2 (pt) | 2005-04-26 | 2010-05-11 | Cargill Inc | método para produzir estereoisÈmeros de monatina ou sal desta, composição compreendendo um precursor de r-monatina e enzimas d-aminotransferase e racemase |
| US8076108B2 (en) | 2005-04-26 | 2011-12-13 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
| WO2007103389A2 (en) | 2006-03-07 | 2007-09-13 | Cargill, Incorporated | Aldolases, nucleic acids encoding them and methods for making and using them |
-
2007
- 2007-05-23 AU AU2007267618A patent/AU2007267618B2/en not_active Expired - Fee Related
- 2007-05-23 BR BRPI0711972-0A patent/BRPI0711972A2/pt not_active Application Discontinuation
- 2007-05-23 CN CNA200780027087XA patent/CN101490249A/zh active Pending
- 2007-05-23 WO PCT/US2007/069513 patent/WO2007140195A2/en not_active Ceased
- 2007-05-23 EP EP07784058A patent/EP2038405A4/en not_active Withdrawn
- 2007-05-23 CA CA002653054A patent/CA2653054A1/en not_active Abandoned
- 2007-05-23 US US11/752,492 patent/US7888081B2/en not_active Expired - Fee Related
- 2007-05-23 JP JP2009512277A patent/JP2009538145A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2653054A1 (en) | 2007-12-06 |
| JP2009538145A (ja) | 2009-11-05 |
| AU2007267618A1 (en) | 2007-12-06 |
| EP2038405A4 (en) | 2009-10-21 |
| EP2038405A2 (en) | 2009-03-25 |
| AU2007267618B2 (en) | 2013-07-18 |
| BRPI0711972A2 (pt) | 2012-01-10 |
| WO2007140195A3 (en) | 2008-10-16 |
| US7888081B2 (en) | 2011-02-15 |
| WO2007140195A2 (en) | 2007-12-06 |
| US20080015361A1 (en) | 2008-01-17 |
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