ATE522497T1 - Verfahren zur herstellung eines glutaminsäurederivats, ein pyroglutaminsäurederivat und ein neues zwischenprodukt für die herstellung - Google Patents

Verfahren zur herstellung eines glutaminsäurederivats, ein pyroglutaminsäurederivat und ein neues zwischenprodukt für die herstellung

Info

Publication number
ATE522497T1
ATE522497T1 AT03815609T AT03815609T ATE522497T1 AT E522497 T1 ATE522497 T1 AT E522497T1 AT 03815609 T AT03815609 T AT 03815609T AT 03815609 T AT03815609 T AT 03815609T AT E522497 T1 ATE522497 T1 AT E522497T1
Authority
AT
Austria
Prior art keywords
acid derivative
protected hydroxyl
glutamic acid
pyroglutamic acid
producing
Prior art date
Application number
AT03815609T
Other languages
English (en)
Inventor
Yusuke Amino
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of ATE522497T1 publication Critical patent/ATE522497T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/22—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from lactams, cyclic ketones or cyclic oximes, e.g. by reactions involving Beckmann rearrangement
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT03815609T 2003-01-09 2003-12-26 Verfahren zur herstellung eines glutaminsäurederivats, ein pyroglutaminsäurederivat und ein neues zwischenprodukt für die herstellung ATE522497T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003003626 2003-01-09
PCT/JP2003/017016 WO2004067494A1 (ja) 2003-01-09 2003-12-26 グルタミン酸誘導体及びピログルタミン酸誘導体の製造方法並びに新規製造中間体

Publications (1)

Publication Number Publication Date
ATE522497T1 true ATE522497T1 (de) 2011-09-15

Family

ID=32820504

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03815609T ATE522497T1 (de) 2003-01-09 2003-12-26 Verfahren zur herstellung eines glutaminsäurederivats, ein pyroglutaminsäurederivat und ein neues zwischenprodukt für die herstellung

Country Status (11)

Country Link
US (2) US7674915B2 (de)
EP (1) EP1582514B1 (de)
JP (1) JP4770174B2 (de)
KR (1) KR101160473B1 (de)
CN (1) CN100408552C (de)
AT (1) ATE522497T1 (de)
AU (1) AU2003301508A1 (de)
BR (1) BR0317958A (de)
CA (1) CA2512752C (de)
RU (1) RU2342360C2 (de)
WO (1) WO2004067494A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7297800B2 (en) 2001-12-27 2007-11-20 Ajinomoto Co., Inc. Process of producing glutamate derivatives
US8372989B2 (en) 2002-04-23 2013-02-12 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
US7572607B2 (en) * 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
EP1533376B1 (de) 2002-08-26 2010-04-07 Ajinomoto Co., Inc. Neue aldolasen und verfahren zur herstellung von substituierter alpha-ketosäure
CA2507225C (en) 2002-12-09 2012-02-07 Ajinomoto Co., Inc. Mutated d-aminotransferase and method for producing optically active glutamic acid derivatives using the same
ATE522497T1 (de) 2003-01-09 2011-09-15 Ajinomoto Kk Verfahren zur herstellung eines glutaminsäurederivats, ein pyroglutaminsäurederivat und ein neues zwischenprodukt für die herstellung
WO2005014839A2 (en) * 2003-08-01 2005-02-17 Cargill, Incorporated Monatin tabletop sweetener compositions and methods of making same
US20050106305A1 (en) * 2003-08-25 2005-05-19 Cargill, Inc. Beverage compositions comprising monatin and methods of making same
AU2004286207B2 (en) * 2003-10-21 2011-02-24 Cargill, Incorporated Production of monatin and monatin precursors
US7935377B2 (en) * 2004-06-04 2011-05-03 Ajinomoto Co., Inc. Crystals of free (2R, 4R)-monatin and use thereof
KR101205568B1 (ko) 2004-10-15 2012-11-27 아지노모토 가부시키가이샤 감미료 조성물
US8158389B2 (en) * 2005-04-20 2012-04-17 Cargill, Incorporated Products and methods for in vivo secretion of monatin
WO2006113897A2 (en) * 2005-04-20 2006-10-26 Cargill, Incorporated Products and methods for in vivo secretion of monatin
US8076108B2 (en) * 2005-04-26 2011-12-13 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
US7582455B2 (en) * 2005-04-26 2009-09-01 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
CA2643416C (en) 2006-03-07 2016-07-26 Cargill, Incorporated Aldolases, nucleic acids encoding them and methods for making and using them
JP2009538145A (ja) * 2006-05-24 2009-11-05 カーギル・インコーポレイテッド 平衡反応の収量を増加させるための方法およびシステム
US20090198072A1 (en) * 2006-05-24 2009-08-06 Cargill, Incorporated Methods and systems for increasing production of equilibrium reactions
CN101239941B (zh) 2007-02-08 2012-02-29 味之素株式会社 光学活性化合物的制造方法
US8367847B2 (en) * 2007-10-01 2013-02-05 Cargill, Incorporated Production of monatin enantiomers
US8003361B2 (en) * 2007-10-01 2011-08-23 Cargill Incorporated Production of monatin enantiomers
US8076107B2 (en) * 2007-10-01 2011-12-13 Cargill, Incorporated Production of monatin stereoisomers
EP2107053A1 (de) * 2008-03-11 2009-10-07 Ajinomoto Co., Inc. Hydratkristalle von (2R,4R)-Monatin Mononatrium-Salz
CN107398303B (zh) * 2016-05-19 2018-08-07 兰州金润宏成石油化工科技有限公司 一种用于生产环氧乙烷的催化剂载体及其制备方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2205834B (en) * 1987-06-15 1990-10-31 South African Inventions 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl)-indole compounds
DK172753B1 (da) * 1988-05-25 1999-06-28 Lilly Co Eli N-(5,6,7,8-tetrahydropyrido[2,3--d]pyrimidin-6-yl-alkanoyl)-glutaminsyrederivater, deres anvendelse, farmaceutiske præparat
JPH02311491A (ja) * 1989-05-26 1990-12-27 Ajinomoto Co Inc ヌクレオシド誘導体の製造方法
DE69101791T2 (de) * 1990-01-19 1994-08-11 Technology Finance Corp Verfahren zur Herstellung von 3-(1-Amino-1,3-dicarboxy-3-hydroxy-but-4-yl)-indol.
US5994559A (en) 1998-08-06 1999-11-30 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Synthesis of monatin-A high intensity natural sweetener
WO2001018034A1 (en) * 1999-09-07 2001-03-15 Ajinomoto Co., Inc. Process for producing aspartame derivative, method of purifying the same, crystals thereof and use of the same
CN1253423C (zh) * 1999-10-07 2006-04-26 味之素株式会社 天冬氨酰基缩二氨酸酯衍生物的制备方法、及其新型制备中间体及该中间体的制备方法
JP2002060382A (ja) * 2000-08-22 2002-02-26 Ajinomoto Co Inc モナティンの立体異性体及びその使用、並びにモナティン類の製造方法及びそのための中間体
EP1466890B1 (de) * 2001-12-27 2012-04-04 Ajinomoto Co., Inc. "verfahren zur herstellung von glutaminsäureverbindungen und zwischenprodukten davon, und in den verfahren verwendete neue zwischenprodukte"
JP2003292484A (ja) * 2002-04-01 2003-10-15 Ajinomoto Co Inc γ−ヒドロキシアミノ酸誘導体及びモナティン類の製造方法
ATE522497T1 (de) 2003-01-09 2011-09-15 Ajinomoto Kk Verfahren zur herstellung eines glutaminsäurederivats, ein pyroglutaminsäurederivat und ein neues zwischenprodukt für die herstellung
JP4217954B2 (ja) 2003-02-12 2009-02-04 富士ゼロックス株式会社 画像探索装置

Also Published As

Publication number Publication date
US8394970B2 (en) 2013-03-12
US20060009394A1 (en) 2006-01-12
WO2004067494A1 (ja) 2004-08-12
KR20050091773A (ko) 2005-09-15
EP1582514A4 (de) 2006-09-13
CN100408552C (zh) 2008-08-06
CA2512752C (en) 2012-05-29
JPWO2004067494A1 (ja) 2006-05-18
EP1582514A1 (de) 2005-10-05
CN1756734A (zh) 2006-04-05
CA2512752A1 (en) 2004-08-12
JP4770174B2 (ja) 2011-09-14
BR0317958A (pt) 2005-11-29
RU2342360C2 (ru) 2008-12-27
US20100010234A1 (en) 2010-01-14
RU2005125207A (ru) 2006-01-10
AU2003301508A1 (en) 2004-08-23
US7674915B2 (en) 2010-03-09
KR101160473B1 (ko) 2012-06-28
EP1582514B1 (de) 2011-08-31

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