ATE552242T1 - ßVERFAHREN ZUR HERSTELLUNG VON GLUTAMINSÄUREVERBINDUNGEN UND ZWISCHENPRODUKTEN DAVON, UND IN DEN VERFAHREN VERWENDETE NEUE ZWISCHENPRODUKTEß - Google Patents

ßVERFAHREN ZUR HERSTELLUNG VON GLUTAMINSÄUREVERBINDUNGEN UND ZWISCHENPRODUKTEN DAVON, UND IN DEN VERFAHREN VERWENDETE NEUE ZWISCHENPRODUKTEß

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Publication number
ATE552242T1
ATE552242T1 AT02783682T AT02783682T ATE552242T1 AT E552242 T1 ATE552242 T1 AT E552242T1 AT 02783682 T AT02783682 T AT 02783682T AT 02783682 T AT02783682 T AT 02783682T AT E552242 T1 ATE552242 T1 AT E552242T1
Authority
AT
Austria
Prior art keywords
intermediate products
preparation
acid compounds
acid compound
intermediates
Prior art date
Application number
AT02783682T
Other languages
English (en)
Inventor
Shigeru Kawahara
Yusuke Amino
Kenichi Mori
Nao Funakoshi
Tadashi Takemoto
Original Assignee
Ajinomoto Kk
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27482750&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE552242(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of ATE552242T1 publication Critical patent/ATE552242T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
    • A23L2/60Sweeteners
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • A23L27/31Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/24Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C07C51/38Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT02783682T 2001-12-27 2002-11-29 ßVERFAHREN ZUR HERSTELLUNG VON GLUTAMINSÄUREVERBINDUNGEN UND ZWISCHENPRODUKTEN DAVON, UND IN DEN VERFAHREN VERWENDETE NEUE ZWISCHENPRODUKTEß ATE552242T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2001396300 2001-12-27
JP2002149078 2002-05-23
JP2002149069 2002-05-23
JP2002182032 2002-06-21
PCT/JP2002/012473 WO2003059865A1 (fr) 2001-12-27 2002-11-29 Procedes de preparation de composes d'acide glutamique et d'intermediaires desdits composes, et nouveaux intermediaires utilises dans lesdits procedes

Publications (1)

Publication Number Publication Date
ATE552242T1 true ATE552242T1 (de) 2012-04-15

Family

ID=27482750

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02783682T ATE552242T1 (de) 2001-12-27 2002-11-29 ßVERFAHREN ZUR HERSTELLUNG VON GLUTAMINSÄUREVERBINDUNGEN UND ZWISCHENPRODUKTEN DAVON, UND IN DEN VERFAHREN VERWENDETE NEUE ZWISCHENPRODUKTEß

Country Status (10)

Country Link
US (6) US7064219B2 (de)
EP (1) EP1466890B1 (de)
JP (2) JP4196832B2 (de)
KR (1) KR100906947B1 (de)
CN (2) CN100465156C (de)
AT (1) ATE552242T1 (de)
AU (1) AU2002349606A1 (de)
CA (1) CA2471847C (de)
ES (1) ES2383518T3 (de)
WO (1) WO2003059865A1 (de)

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RU2303030C2 (ru) * 2001-11-30 2007-07-20 Адзиномото Ко., Инк. Кристаллы соли неприродного стереоизомера монатина и их применение
US7297800B2 (en) 2001-12-27 2007-11-20 Ajinomoto Co., Inc. Process of producing glutamate derivatives
CA2469012C (en) * 2001-12-27 2013-06-04 Ajinomoto Co., Inc. Process of producing glutamate derivatives
KR100906947B1 (ko) 2001-12-27 2009-07-09 아지노모토 가부시키가이샤 글루탐산 화합물 및 이의 제조 중간체의 제조방법 및 이를 위한 신규 중간체
US7572607B2 (en) 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
US8372989B2 (en) 2002-04-23 2013-02-12 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
WO2004018672A1 (ja) 2002-08-26 2004-03-04 Ajinomoto Co., Inc. 新規アルドラーゼおよび置換α−ケト酸の製造方法
EP1580268B1 (de) 2002-12-09 2013-10-02 Ajinomoto Co., Inc. D-aminotransferasemutante und verfahren zur herstellung eines optisch aktiven glutaminsäurederivats unter verwendung davon
RU2342360C2 (ru) * 2003-01-09 2008-12-27 Адзиномото Ко., Инк. Способ получения производного глутаминовой кислоты и производного пироглутаминовой кислоты и новое промежуточное соединение для получения этих производных
WO2005014839A2 (en) * 2003-08-01 2005-02-17 Cargill, Incorporated Monatin tabletop sweetener compositions and methods of making same
BRPI0413931A (pt) * 2003-08-25 2006-10-24 Cargill Inc composições de bebida compreendendo monatina e métodos para sua fabricação
ATE498691T1 (de) 2003-10-21 2011-03-15 Cargill Inc Herstellung von monatin und monatinvorstufen
JP5113978B2 (ja) * 2003-11-21 2013-01-09 味の素株式会社 グルタミン酸誘導体の有機アミン塩及びその利用
CA2557274C (en) 2004-02-27 2012-12-04 Ajinomoto Co., Inc. Method for producing monatin
US7935377B2 (en) * 2004-06-04 2011-05-03 Ajinomoto Co., Inc. Crystals of free (2R, 4R)-monatin and use thereof
CA2506247C (en) 2004-06-07 2012-02-21 Ajinomoto Co., Inc. Novel aldolase, and method for producing optically active ihog and monatin
KR101216575B1 (ko) * 2004-07-14 2012-12-31 아지노모토 가부시키가이샤 (2r,4r)-모나틴 칼륨 염 결정 및 이를 함유하는 감미료조성물
US7180370B2 (en) * 2004-09-01 2007-02-20 Micron Technology, Inc. CMOS amplifiers with frequency compensating capacitors
WO2006038520A1 (ja) * 2004-10-05 2006-04-13 Ajinomoto Co., Inc. ヒドロキシイミノ酸からのアミノ酸誘導体製造方法
KR101205568B1 (ko) * 2004-10-15 2012-11-27 아지노모토 가부시키가이샤 감미료 조성물
CN101223444B (zh) 2005-04-20 2013-04-24 嘉吉有限公司 在体内分泌莫纳甜的方法
US8158389B2 (en) 2005-04-20 2012-04-17 Cargill, Incorporated Products and methods for in vivo secretion of monatin
US8076108B2 (en) 2005-04-26 2011-12-13 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
US7582455B2 (en) 2005-04-26 2009-09-01 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
CN101437954B (zh) 2006-03-07 2015-09-09 嘉吉公司 醛缩酶和编码醛缩酶的核酸以及它们的制备和使用方法
US20090198072A1 (en) * 2006-05-24 2009-08-06 Cargill, Incorporated Methods and systems for increasing production of equilibrium reactions
AU2007267618B2 (en) 2006-05-24 2013-07-18 Cargill, Incorporated Methods and systems for increasing production of equilibrium reactions
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
CN101239941B (zh) 2007-02-08 2012-02-29 味之素株式会社 光学活性化合物的制造方法
US8367847B2 (en) 2007-10-01 2013-02-05 Cargill, Incorporated Production of monatin enantiomers
US8076107B2 (en) 2007-10-01 2011-12-13 Cargill, Incorporated Production of monatin stereoisomers
US8003361B2 (en) 2007-10-01 2011-08-23 Cargill Incorporated Production of monatin enantiomers
EP2107053A1 (de) 2008-03-11 2009-10-07 Ajinomoto Co., Inc. Hydratkristalle von (2R,4R)-Monatin Mononatrium-Salz
RU2505606C2 (ru) * 2010-10-14 2014-01-27 Адзиномото Ко., Инк. Способ получения монатина
US8771997B2 (en) 2011-04-20 2014-07-08 Ajinomoto Co., Inc. Method for producing monatin using an L-amino acid aminotransferase
CN115806481A (zh) * 2022-12-05 2023-03-17 安徽丰乐香料有限责任公司 L-薄荷基甲酸的分离提纯方法

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CA2506247C (en) * 2004-06-07 2012-02-21 Ajinomoto Co., Inc. Novel aldolase, and method for producing optically active ihog and monatin
KR101216575B1 (ko) * 2004-07-14 2012-12-31 아지노모토 가부시키가이샤 (2r,4r)-모나틴 칼륨 염 결정 및 이를 함유하는 감미료조성물
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CN101239941B (zh) * 2007-02-08 2012-02-29 味之素株式会社 光学活性化合物的制造方法
EP2107053A1 (de) * 2008-03-11 2009-10-07 Ajinomoto Co., Inc. Hydratkristalle von (2R,4R)-Monatin Mononatrium-Salz

Also Published As

Publication number Publication date
EP1466890A4 (de) 2005-01-26
CN101450907B (zh) 2013-07-17
CN100465156C (zh) 2009-03-04
US20080091032A1 (en) 2008-04-17
KR100906947B1 (ko) 2009-07-09
US7868187B2 (en) 2011-01-11
JPWO2003059865A1 (ja) 2005-05-19
AU2002349606A1 (en) 2003-07-30
US7678925B2 (en) 2010-03-16
CN1610658A (zh) 2005-04-27
ES2383518T3 (es) 2012-06-21
US20060074249A1 (en) 2006-04-06
JP2009046488A (ja) 2009-03-05
EP1466890A1 (de) 2004-10-13
US20120035373A1 (en) 2012-02-09
WO2003059865A1 (fr) 2003-07-24
US20090259052A1 (en) 2009-10-15
CN101450907A (zh) 2009-06-10
US20100105924A1 (en) 2010-04-29
US20050004394A1 (en) 2005-01-06
US7390909B2 (en) 2008-06-24
KR20040076269A (ko) 2004-08-31
JP4905426B2 (ja) 2012-03-28
EP1466890B1 (de) 2012-04-04
CA2471847C (en) 2012-05-15
US7064219B2 (en) 2006-06-20
JP4196832B2 (ja) 2008-12-17
CA2471847A1 (en) 2003-07-24

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