DE60115954D1 - Verfahren zur herstellung von gabapentin - Google Patents

Verfahren zur herstellung von gabapentin

Info

Publication number
DE60115954D1
DE60115954D1 DE60115954T DE60115954T DE60115954D1 DE 60115954 D1 DE60115954 D1 DE 60115954D1 DE 60115954 T DE60115954 T DE 60115954T DE 60115954 T DE60115954 T DE 60115954T DE 60115954 D1 DE60115954 D1 DE 60115954D1
Authority
DE
Germany
Prior art keywords
preparation
gabapentin
relates
cyclohexane
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60115954T
Other languages
English (en)
Other versions
DE60115954T2 (de
Inventor
Vincenzo Cannata
Andrea Nicoli
Francesco Corcella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zach System SpA
Original Assignee
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon SpA filed Critical Zambon SpA
Application granted granted Critical
Publication of DE60115954D1 publication Critical patent/DE60115954D1/de
Publication of DE60115954T2 publication Critical patent/DE60115954T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B60—VEHICLES IN GENERAL
    • B60R—VEHICLES, VEHICLE FITTINGS, OR VEHICLE PARTS, NOT OTHERWISE PROVIDED FOR
    • B60R16/00—Electric or fluid circuits specially adapted for vehicles and not otherwise provided for; Arrangement of elements of electric or fluid circuits specially adapted for vehicles and not otherwise provided for
    • B60R16/02—Electric or fluid circuits specially adapted for vehicles and not otherwise provided for; Arrangement of elements of electric or fluid circuits specially adapted for vehicles and not otherwise provided for electric constitutive elements
    • B60R16/0207—Wire harnesses
    • B60R16/0215—Protecting, fastening and routing means therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38—Separation; Purification; Stabilisation; Use of additives
    • C07C227/40—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
DE60115954T 2000-10-23 2001-10-15 Verfahren zur herstellung von gabapentin Expired - Lifetime DE60115954T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI20002285 2000-10-23
IT2000MI002285A IT1319234B1 (it) 2000-10-23 2000-10-23 Processo di preparazione di gabapentina.
PCT/EP2001/011867 WO2002034709A1 (en) 2000-10-23 2001-10-15 Process for the preparation of gabapentin

Publications (2)

Publication Number Publication Date
DE60115954D1 true DE60115954D1 (de) 2006-01-19
DE60115954T2 DE60115954T2 (de) 2006-09-07

Family

ID=11446013

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60115954T Expired - Lifetime DE60115954T2 (de) 2000-10-23 2001-10-15 Verfahren zur herstellung von gabapentin

Country Status (14)

Country Link
US (2) US7199266B2 (de)
EP (2) EP1341749B1 (de)
JP (1) JP4723794B2 (de)
AT (1) ATE312809T1 (de)
CA (1) CA2425615C (de)
CY (1) CY1106481T1 (de)
DE (1) DE60115954T2 (de)
DK (1) DK1341749T3 (de)
ES (2) ES2254528T3 (de)
GB (1) GB2383041B (de)
HU (1) HUP0302602A2 (de)
IL (2) IL154789A0 (de)
IT (1) IT1319234B1 (de)
WO (1) WO2002034709A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1319234B1 (it) 2000-10-23 2003-09-26 Zambon Spa Processo di preparazione di gabapentina.
AU2003262383A1 (en) * 2002-04-16 2003-11-03 Taro Pharmaceutical Industries Ltd. Process for preparing gabapentin
PT1603863E (pt) * 2002-11-20 2010-02-05 Hikal Ltd Processo para a preparação de ácidos amino-metil-cicloalcano-acéticos
WO2004093779A2 (en) * 2003-04-21 2004-11-04 Matrix Laboratories Ltd Process for the preparation of gabapentin form-ii
WO2004093780A2 (en) * 2003-04-21 2004-11-04 Matrix Laboratories Ltd Process for the preparation of gabapentin form-ii
US20070043236A1 (en) * 2003-05-19 2007-02-22 Chandiran Thakashina M Process for preparation of gabapentin
ITMI20031247A1 (it) * 2003-06-20 2004-12-21 Zambon Spa Processo per la purificazione di gabapentina
ITMI20032165A1 (it) * 2003-11-11 2005-05-12 Zambon Spa Processo di preparazione di gabapentina
ITMI20032456A1 (it) * 2003-12-16 2005-06-17 Zambon Spa Processo per la purificazione di gabapentina
ITMI20040579A1 (it) 2004-03-25 2004-06-25 Zambon Spa Processo di preparazione di gabapentina
ITMI20041271A1 (it) * 2004-06-24 2004-09-24 Zambon Spa Processo di preparazione di gabapentina
GB0416228D0 (en) * 2004-07-20 2004-08-25 Sandoz Ind Products S A Process for the preparation of gabapentin
ITMI20042418A1 (it) * 2004-12-17 2005-03-17 Zambon Spa Processo per la purificazione della gabapentina
US7442834B2 (en) 2006-06-12 2008-10-28 Zhejiang Chiral Medicine Chemicals Co., Ltd. Process suitable for industrial scale production of gabapentin
WO2008106217A1 (en) * 2007-02-28 2008-09-04 Teva Pharmaceutical Industries Ltd. Preparation of gabapentin by liquid-liquid extraction
EP2368872A1 (de) 2010-03-25 2011-09-28 Serichim S.r.l. Verfahren zur Herstellung von Gabapentin
ITMI20131757A1 (it) 2013-10-22 2015-04-23 Zach System Spa Processo di preparazione di gabapentina

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1145512A (en) 1965-09-21 1969-03-19 Kyowa Hakko Kogyo Company Ltd Method for isolating tryptophan
US4087544A (en) * 1974-12-21 1978-05-02 Warner-Lambert Company Treatment of cranial dysfunctions using novel cyclic amino acids
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
JPS6261592A (ja) * 1985-09-13 1987-03-18 Ajinomoto Co Inc 塩基性アミノ酸の分離方法
DE3928183A1 (de) 1989-08-25 1991-02-28 Goedecke Ag Lactamfreie cyclische aminosaeuren
JPH04134054A (ja) * 1990-09-25 1992-05-07 Ajinomoto Co Inc イオン交換樹脂を用いるアミノ酸の精製方法
HU217844B (hu) 1994-11-18 2000-04-28 Aeci Limited Eljárás aminosav kinyerésére
JPH08183768A (ja) 1994-12-28 1996-07-16 Mitsui Toatsu Chem Inc Ｌ−プロリンの単離法
ES2164527B1 (es) 1999-04-26 2003-04-01 Medichen S A Procedimiento de obtencion de gabapentina de calidad farmaceutica.
IT1319234B1 (it) * 2000-10-23 2003-09-26 Zambon Spa Processo di preparazione di gabapentina.
AU2003262383A1 (en) 2002-04-16 2003-11-03 Taro Pharmaceutical Industries Ltd. Process for preparing gabapentin

Also Published As

Publication number Publication date
GB0306346D0 (en) 2003-04-23
CA2425615A1 (en) 2002-05-02
CA2425615C (en) 2011-05-24
EP1475366A1 (de) 2004-11-10
ES2206078A1 (es) 2004-05-01
US7365227B2 (en) 2008-04-29
US20070043237A1 (en) 2007-02-22
US20040068011A1 (en) 2004-04-08
CY1106481T1 (el) 2012-10-24
GB2383041A (en) 2003-06-18
WO2002034709A1 (en) 2002-05-02
IT1319234B1 (it) 2003-09-26
DE60115954T2 (de) 2006-09-07
JP2004512321A (ja) 2004-04-22
IL154789A0 (en) 2003-10-31
ATE312809T1 (de) 2005-12-15
ES2254528T3 (es) 2006-06-16
GB2383041B (en) 2004-11-17
ITMI20002285A1 (it) 2002-04-23
EP1341749B1 (de) 2005-12-14
IL154789A (en) 2008-11-03
EP1341749A1 (de) 2003-09-10
ES2206078B1 (es) 2005-08-01
DK1341749T3 (da) 2006-04-18
US7199266B2 (en) 2007-04-03
HUP0302602A2 (hu) 2003-11-28
JP4723794B2 (ja) 2011-07-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ZACH SYSTEM S.P.A., BRESSO, (MILANO), IT