CY1106481T1 - Διαδικασια για την παρασκευη γαβαπεντινης - Google Patents
Διαδικασια για την παρασκευη γαβαπεντινηςInfo
- Publication number
- CY1106481T1 CY1106481T1 CY20061100328T CY061100328T CY1106481T1 CY 1106481 T1 CY1106481 T1 CY 1106481T1 CY 20061100328 T CY20061100328 T CY 20061100328T CY 061100328 T CY061100328 T CY 061100328T CY 1106481 T1 CY1106481 T1 CY 1106481T1
- Authority
- CY
- Cyprus
- Prior art keywords
- gavapentin
- procedure
- preparation
- gabapentin
- converting
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical compound OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 abstract 2
- XBUDZAQEMFGLEU-UHFFFAOYSA-N 2-[1-(aminomethyl)cyclohexyl]acetic acid;hydron;chloride Chemical compound Cl.OC(=O)CC1(CN)CCCCC1 XBUDZAQEMFGLEU-UHFFFAOYSA-N 0.000 abstract 1
- 239000003729 cation exchange resin Substances 0.000 abstract 1
- 229960002870 gabapentin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60R—VEHICLES, VEHICLE FITTINGS, OR VEHICLE PARTS, NOT OTHERWISE PROVIDED FOR
- B60R16/00—Electric or fluid circuits specially adapted for vehicles and not otherwise provided for; Arrangement of elements of electric or fluid circuits specially adapted for vehicles and not otherwise provided for
- B60R16/02—Electric or fluid circuits specially adapted for vehicles and not otherwise provided for; Arrangement of elements of electric or fluid circuits specially adapted for vehicles and not otherwise provided for electric constitutive elements
- B60R16/0207—Wire harnesses
- B60R16/0215—Protecting, fastening and routing means therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Abstract
Διαδικασία για τον καθαρισμό υδροχλωριδίου γαβαπεντίνης και για τη μετατροπή του σε γαβαπεντίνη με επεξεργασία με μια ισχυρή κατιονική ρητίνη ανταλλαγής ιόντων.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2000MI002285A IT1319234B1 (it) | 2000-10-23 | 2000-10-23 | Processo di preparazione di gabapentina. |
EP01988708A EP1341749B1 (en) | 2000-10-23 | 2001-10-15 | Process for the preparation of gabapentin |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1106481T1 true CY1106481T1 (el) | 2012-10-24 |
Family
ID=11446013
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20061100328T CY1106481T1 (el) | 2000-10-23 | 2006-03-09 | Διαδικασια για την παρασκευη γαβαπεντινης |
Country Status (14)
Country | Link |
---|---|
US (2) | US7199266B2 (el) |
EP (2) | EP1475366A1 (el) |
JP (1) | JP4723794B2 (el) |
AT (1) | ATE312809T1 (el) |
CA (1) | CA2425615C (el) |
CY (1) | CY1106481T1 (el) |
DE (1) | DE60115954T2 (el) |
DK (1) | DK1341749T3 (el) |
ES (2) | ES2254528T3 (el) |
GB (1) | GB2383041B (el) |
HU (1) | HUP0302602A2 (el) |
IL (2) | IL154789A0 (el) |
IT (1) | IT1319234B1 (el) |
WO (1) | WO2002034709A1 (el) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1319234B1 (it) | 2000-10-23 | 2003-09-26 | Zambon Spa | Processo di preparazione di gabapentina. |
CA2478471A1 (en) * | 2002-04-16 | 2003-10-30 | Taro Pharmaceutical Industries Ltd. | Process for preparing gabapentin |
ATE455089T1 (de) * | 2002-11-20 | 2010-01-15 | Hikal Ltd | Verfahren zur herstellung von aminomethylcycloalkan-essigsäuren |
WO2004093779A2 (en) * | 2003-04-21 | 2004-11-04 | Matrix Laboratories Ltd | Process for the preparation of gabapentin form-ii |
EP1615875A2 (en) * | 2003-04-21 | 2006-01-18 | Matrix Laboratories Limited | Process for the preparation of gabapentin form-ii |
US20070043236A1 (en) * | 2003-05-19 | 2007-02-22 | Chandiran Thakashina M | Process for preparation of gabapentin |
ITMI20031247A1 (it) | 2003-06-20 | 2004-12-21 | Zambon Spa | Processo per la purificazione di gabapentina |
ITMI20032165A1 (it) * | 2003-11-11 | 2005-05-12 | Zambon Spa | Processo di preparazione di gabapentina |
ITMI20032456A1 (it) | 2003-12-16 | 2005-06-17 | Zambon Spa | Processo per la purificazione di gabapentina |
ITMI20040579A1 (it) | 2004-03-25 | 2004-06-25 | Zambon Spa | Processo di preparazione di gabapentina |
ITMI20041271A1 (it) * | 2004-06-24 | 2004-09-24 | Zambon Spa | Processo di preparazione di gabapentina |
GB0416228D0 (en) * | 2004-07-20 | 2004-08-25 | Sandoz Ind Products S A | Process for the preparation of gabapentin |
ITMI20042418A1 (it) * | 2004-12-17 | 2005-03-17 | Zambon Spa | Processo per la purificazione della gabapentina |
US7442834B2 (en) | 2006-06-12 | 2008-10-28 | Zhejiang Chiral Medicine Chemicals Co., Ltd. | Process suitable for industrial scale production of gabapentin |
WO2008106217A1 (en) * | 2007-02-28 | 2008-09-04 | Teva Pharmaceutical Industries Ltd. | Preparation of gabapentin by liquid-liquid extraction |
EP2368872A1 (en) * | 2010-03-25 | 2011-09-28 | Serichim S.r.l. | Process for the preparation of Gabapentin |
ITMI20131757A1 (it) | 2013-10-22 | 2015-04-23 | Zach System Spa | Processo di preparazione di gabapentina |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1145512A (en) * | 1965-09-21 | 1969-03-19 | Kyowa Hakko Kogyo Company Ltd | Method for isolating tryptophan |
DE2460891C2 (de) | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
US4087544A (en) * | 1974-12-21 | 1978-05-02 | Warner-Lambert Company | Treatment of cranial dysfunctions using novel cyclic amino acids |
JPS6261592A (ja) * | 1985-09-13 | 1987-03-18 | Ajinomoto Co Inc | 塩基性アミノ酸の分離方法 |
DE3928183A1 (de) | 1989-08-25 | 1991-02-28 | Goedecke Ag | Lactamfreie cyclische aminosaeuren |
JPH04134054A (ja) * | 1990-09-25 | 1992-05-07 | Ajinomoto Co Inc | イオン交換樹脂を用いるアミノ酸の精製方法 |
HU217844B (hu) | 1994-11-18 | 2000-04-28 | Aeci Limited | Eljárás aminosav kinyerésére |
JPH08183768A (ja) * | 1994-12-28 | 1996-07-16 | Mitsui Toatsu Chem Inc | L−プロリンの単離法 |
ES2164527B1 (es) | 1999-04-26 | 2003-04-01 | Medichen S A | Procedimiento de obtencion de gabapentina de calidad farmaceutica. |
IT1319234B1 (it) | 2000-10-23 | 2003-09-26 | Zambon Spa | Processo di preparazione di gabapentina. |
CA2478471A1 (en) * | 2002-04-16 | 2003-10-30 | Taro Pharmaceutical Industries Ltd. | Process for preparing gabapentin |
-
2000
- 2000-10-23 IT IT2000MI002285A patent/IT1319234B1/it active
-
2001
- 2001-10-15 HU HU0302602A patent/HUP0302602A2/hu unknown
- 2001-10-15 ES ES01988708T patent/ES2254528T3/es not_active Expired - Lifetime
- 2001-10-15 WO PCT/EP2001/011867 patent/WO2002034709A1/en not_active IP Right Cessation
- 2001-10-15 US US10/399,409 patent/US7199266B2/en not_active Expired - Lifetime
- 2001-10-15 DE DE60115954T patent/DE60115954T2/de not_active Expired - Lifetime
- 2001-10-15 DK DK01988708T patent/DK1341749T3/da active
- 2001-10-15 EP EP04016428A patent/EP1475366A1/en not_active Ceased
- 2001-10-15 CA CA2425615A patent/CA2425615C/en not_active Expired - Lifetime
- 2001-10-15 GB GB0306346A patent/GB2383041B/en not_active Expired - Fee Related
- 2001-10-15 AT AT01988708T patent/ATE312809T1/de active
- 2001-10-15 JP JP2002537703A patent/JP4723794B2/ja not_active Expired - Fee Related
- 2001-10-15 EP EP01988708A patent/EP1341749B1/en not_active Expired - Lifetime
- 2001-10-15 IL IL15478901A patent/IL154789A0/xx unknown
-
2003
- 2003-03-06 IL IL154789A patent/IL154789A/en not_active IP Right Cessation
- 2003-03-28 ES ES200350018A patent/ES2206078B1/es not_active Expired - Fee Related
-
2006
- 2006-03-09 CY CY20061100328T patent/CY1106481T1/el unknown
- 2006-03-28 US US11/390,451 patent/US7365227B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20040068011A1 (en) | 2004-04-08 |
GB0306346D0 (en) | 2003-04-23 |
DK1341749T3 (da) | 2006-04-18 |
ES2206078B1 (es) | 2005-08-01 |
ITMI20002285A1 (it) | 2002-04-23 |
WO2002034709A1 (en) | 2002-05-02 |
HUP0302602A2 (hu) | 2003-11-28 |
JP4723794B2 (ja) | 2011-07-13 |
JP2004512321A (ja) | 2004-04-22 |
CA2425615C (en) | 2011-05-24 |
ES2206078A1 (es) | 2004-05-01 |
DE60115954T2 (de) | 2006-09-07 |
IL154789A (en) | 2008-11-03 |
ES2254528T3 (es) | 2006-06-16 |
GB2383041B (en) | 2004-11-17 |
US7365227B2 (en) | 2008-04-29 |
EP1341749B1 (en) | 2005-12-14 |
DE60115954D1 (de) | 2006-01-19 |
CA2425615A1 (en) | 2002-05-02 |
IT1319234B1 (it) | 2003-09-26 |
IL154789A0 (en) | 2003-10-31 |
ATE312809T1 (de) | 2005-12-15 |
EP1341749A1 (en) | 2003-09-10 |
US7199266B2 (en) | 2007-04-03 |
US20070043237A1 (en) | 2007-02-22 |
GB2383041A (en) | 2003-06-18 |
EP1475366A1 (en) | 2004-11-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1106481T1 (el) | Διαδικασια για την παρασκευη γαβαπεντινης | |
DE60125409D1 (de) | Polymerisationsverfahren für ionische monomere | |
TR199700627T1 (xx) | Dikkat eksikli�i / hiperaktivite bozuklu�unun tedavisi. | |
DK1663322T3 (da) | Forbedret ozonsteriliseringsfremgangsmåde | |
DE60301590D1 (de) | Vorrichtung zur Produktion von entionisiertem Wasser durch Elektrodenionisation | |
ATE376005T1 (de) | Polymerisationsverfahren | |
BR0016481B1 (pt) | dispositivo para purificar água, e método para tratar água com ozÈnio gerado por eletrólise de água. | |
CY1107911T1 (el) | Διαταξη αφαιρεσεως | |
DE69923979D1 (de) | Vorrichtung zur erzeugung von ionenstrahlen | |
CY1109280T1 (el) | Συμπλοκα του λιθιου με ν-(1-υδροξυμεθυλο-2,3-διυδροξυπροπυλο)-1,4,7-τρισκαρβοξυμεθυλο-1,4,7,10-τετρααζακυκλοδωδεκανιο, η παραγωγη και χρηση αυτων | |
CY1112185T1 (el) | Σταθερο συμπλοκο δραστικων ουσιων απο αλατα των o-ακετυλοσαλικυλικων οξεων με βασικα αμινοξεα και γλυκινη | |
CY1109221T1 (el) | Χιμαιρικο γονιδιο που κωδικοποιει τους αντιγονικους καθοριστες τεσσαρων πρωτεϊνων του l. infantum | |
CY1113871T1 (el) | Διαδικασια παρασκευης γκαμπαπεντινης | |
DE69912626D1 (de) | Mit flüsigkeit dauerbefeuchtbarer durchlässiger stoff, hergestellt mittels entfernten plasma polymerisationsverfahren | |
NL1021504A1 (nl) | Waterstofbehandelingsproces. | |
EA200400802A1 (ru) | pH-ЧУВСТВИТЕЛЬНЫЕ ПОЛИМЕРНЫЕ КОНЪЮГАТЫ АНТРАЦИКЛИНОВЫХ КАНЦЕРОСТАТИЧЕСКИХ АКТИВНЫХ АГЕНТОВ ДЛЯ ТЕРАПИИ НАПРАВЛЕННОГО ДЕЙСТВИЯ | |
BR0213561B1 (pt) | processo para a preparaÇço de amidas de Ácido 2-halopiridincarboxÍlico. | |
ECSP044985A (es) | Azitromicina de dosis única para infecciones respiratorias | |
ITTO20020122A0 (it) | Apparecchio decalcificatore provvisto di mezzi indicatori dell'esaurimento delle resine scambiatrici di ioni. | |
ID27439A (id) | Proses untuk menurunkan tingkat aox resin berkekuatan basah melalui perlakuan dengan basa | |
ATE246145T1 (de) | Reinigung von hydroxylamin | |
CY1105403T1 (el) | Χρηση της ακετυλο-l-καρνιτινης σε συνδυασμο με τη βιοτινη για τη θepαπεια ασθενων με ινσουλινο-ανθεκτικο σακχαρωδη διαβητη τυπου 2 | |
BRPI0412721A (pt) | processo para preparar bromidrato de eletriptano alfa-polimórfico | |
CY1106200T1 (el) | Αντισωματα εναντια σε κασπαση-8, παρασκευη και χρηση τους | |
BR0209842A (pt) | Processo para a preparação de imipenem |