HUP0302602A2 - Eljárás gabapentin előállítására - Google Patents

Eljárás gabapentin előállítására

Info

Publication number
HUP0302602A2
HUP0302602A2 HU0302602A HUP0302602A HUP0302602A2 HU P0302602 A2 HUP0302602 A2 HU P0302602A2 HU 0302602 A HU0302602 A HU 0302602A HU P0302602 A HUP0302602 A HU P0302602A HU P0302602 A2 HUP0302602 A2 HU P0302602A2
Authority
HU
Hungary
Prior art keywords
gabapentin
preparation
ion exchange
exchange resin
resin
Prior art date
Application number
HU0302602A
Other languages
English (en)
Inventor
Vincenzo Cannata
Francesco Corcella
Andrea Nicoli
Original Assignee
Zambon Group S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Group S.P.A. filed Critical Zambon Group S.P.A.
Publication of HUP0302602A2 publication Critical patent/HUP0302602A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B60—VEHICLES IN GENERAL
    • B60R—VEHICLES, VEHICLE FITTINGS, OR VEHICLE PARTS, NOT OTHERWISE PROVIDED FOR
    • B60R16/00—Electric or fluid circuits specially adapted for vehicles and not otherwise provided for; Arrangement of elements of electric or fluid circuits specially adapted for vehicles and not otherwise provided for
    • B60R16/02—Electric or fluid circuits specially adapted for vehicles and not otherwise provided for; Arrangement of elements of electric or fluid circuits specially adapted for vehicles and not otherwise provided for electric constitutive elements
    • B60R16/0207—Wire harnesses
    • B60R16/0215—Protecting, fastening and routing means therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38—Separation; Purification; Stabilisation; Use of additives
    • C07C227/40—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)

Abstract

A találmány tárgya eljárás gabapentin-hidroklorid szerves sóktóltörténő tisztítására és gabapentinné történő átalakítására vizesgabapentin-hidroklorid-oldat ioncserélő gyantával történő kezelésével,amelyben az ioncserélő gyanta erős kationos gyanta. Ó
HU0302602A 2000-10-23 2001-10-15 Eljárás gabapentin előállítására HUP0302602A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000MI002285A IT1319234B1 (it) 2000-10-23 2000-10-23 Processo di preparazione di gabapentina.
PCT/EP2001/011867 WO2002034709A1 (en) 2000-10-23 2001-10-15 Process for the preparation of gabapentin

Publications (1)

Publication Number Publication Date
HUP0302602A2 true HUP0302602A2 (hu) 2003-11-28

Family

ID=11446013

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0302602A HUP0302602A2 (hu) 2000-10-23 2001-10-15 Eljárás gabapentin előállítására

Country Status (14)

Country Link
US (2) US7199266B2 (hu)
EP (2) EP1341749B1 (hu)
JP (1) JP4723794B2 (hu)
AT (1) ATE312809T1 (hu)
CA (1) CA2425615C (hu)
CY (1) CY1106481T1 (hu)
DE (1) DE60115954T2 (hu)
DK (1) DK1341749T3 (hu)
ES (2) ES2254528T3 (hu)
GB (1) GB2383041B (hu)
HU (1) HUP0302602A2 (hu)
IL (2) IL154789A0 (hu)
IT (1) IT1319234B1 (hu)
WO (1) WO2002034709A1 (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1319234B1 (it) 2000-10-23 2003-09-26 Zambon Spa Processo di preparazione di gabapentina.
WO2003089403A1 (en) * 2002-04-16 2003-10-30 Taro Pharmaceutical Industries Ltd. Process for preparing gabapentin
EP1603863B1 (en) * 2002-11-20 2010-01-13 Hikal Ltd. Process for the preparation of amino methyl cyclo alkane acetic acids
WO2004093779A2 (en) * 2003-04-21 2004-11-04 Matrix Laboratories Ltd Process for the preparation of gabapentin form-ii
EP1615875A2 (en) * 2003-04-21 2006-01-18 Matrix Laboratories Limited Process for the preparation of gabapentin form-ii
US20070043236A1 (en) * 2003-05-19 2007-02-22 Chandiran Thakashina M Process for preparation of gabapentin
ITMI20031247A1 (it) 2003-06-20 2004-12-21 Zambon Spa Processo per la purificazione di gabapentina
ITMI20032165A1 (it) * 2003-11-11 2005-05-12 Zambon Spa Processo di preparazione di gabapentina
ITMI20032456A1 (it) 2003-12-16 2005-06-17 Zambon Spa Processo per la purificazione di gabapentina
ITMI20040579A1 (it) 2004-03-25 2004-06-25 Zambon Spa Processo di preparazione di gabapentina
ITMI20041271A1 (it) * 2004-06-24 2004-09-24 Zambon Spa Processo di preparazione di gabapentina
GB0416228D0 (en) * 2004-07-20 2004-08-25 Sandoz Ind Products S A Process for the preparation of gabapentin
ITMI20042418A1 (it) * 2004-12-17 2005-03-17 Zambon Spa Processo per la purificazione della gabapentina
US7442834B2 (en) 2006-06-12 2008-10-28 Zhejiang Chiral Medicine Chemicals Co., Ltd. Process suitable for industrial scale production of gabapentin
US20080207945A1 (en) * 2007-02-28 2008-08-28 Ziv Dee-Noor Preparation of gabapentin by liquid-liquid extraction
EP2368872A1 (en) * 2010-03-25 2011-09-28 Serichim S.r.l. Process for the preparation of Gabapentin
ITMI20131757A1 (it) 2013-10-22 2015-04-23 Zach System Spa Processo di preparazione di gabapentina

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1145512A (en) * 1965-09-21 1969-03-19 Kyowa Hakko Kogyo Company Ltd Method for isolating tryptophan
US4087544A (en) * 1974-12-21 1978-05-02 Warner-Lambert Company Treatment of cranial dysfunctions using novel cyclic amino acids
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
JPS6261592A (ja) 1985-09-13 1987-03-18 Ajinomoto Co Inc 塩基性アミノ酸の分離方法
DE3928183A1 (de) * 1989-08-25 1991-02-28 Goedecke Ag Lactamfreie cyclische aminosaeuren
JPH04134054A (ja) 1990-09-25 1992-05-07 Ajinomoto Co Inc イオン交換樹脂を用いるアミノ酸の精製方法
HU217844B (hu) 1994-11-18 2000-04-28 Aeci Limited Eljárás aminosav kinyerésére
JPH08183768A (ja) * 1994-12-28 1996-07-16 Mitsui Toatsu Chem Inc Ｌ−プロリンの単離法
ES2164527B1 (es) 1999-04-26 2003-04-01 Medichen S A Procedimiento de obtencion de gabapentina de calidad farmaceutica.
IT1319234B1 (it) 2000-10-23 2003-09-26 Zambon Spa Processo di preparazione di gabapentina.
WO2003089403A1 (en) * 2002-04-16 2003-10-30 Taro Pharmaceutical Industries Ltd. Process for preparing gabapentin

Also Published As

Publication number Publication date
JP2004512321A (ja) 2004-04-22
CA2425615C (en) 2011-05-24
EP1475366A1 (en) 2004-11-10
IL154789A (en) 2008-11-03
US7365227B2 (en) 2008-04-29
ATE312809T1 (de) 2005-12-15
JP4723794B2 (ja) 2011-07-13
ITMI20002285A1 (it) 2002-04-23
IL154789A0 (en) 2003-10-31
DE60115954D1 (de) 2006-01-19
US20070043237A1 (en) 2007-02-22
ES2254528T3 (es) 2006-06-16
GB2383041B (en) 2004-11-17
ES2206078A1 (es) 2004-05-01
EP1341749B1 (en) 2005-12-14
CY1106481T1 (el) 2012-10-24
CA2425615A1 (en) 2002-05-02
IT1319234B1 (it) 2003-09-26
WO2002034709A1 (en) 2002-05-02
US20040068011A1 (en) 2004-04-08
US7199266B2 (en) 2007-04-03
GB0306346D0 (en) 2003-04-23
EP1341749A1 (en) 2003-09-10
GB2383041A (en) 2003-06-18
DK1341749T3 (da) 2006-04-18
ES2206078B1 (es) 2005-08-01
DE60115954T2 (de) 2006-09-07

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Legal Events

Date Code Title Description
FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished