BR0308753A - Método para produzir pseudo-ilhotas - Google Patents
Método para produzir pseudo-ilhotasInfo
- Publication number
- BR0308753A BR0308753A BR0308753-0A BR0308753A BR0308753A BR 0308753 A BR0308753 A BR 0308753A BR 0308753 A BR0308753 A BR 0308753A BR 0308753 A BR0308753 A BR 0308753A
- Authority
- BR
- Brazil
- Prior art keywords
- islets
- producing pseudo
- relates
- present
- diabetes
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1323—Adult fibroblasts
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/02—Drug screening
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
Abstract
"MéTODO PARA PRODUZIR PSEUDO-ILHOTAS". A presente invenção refere-se a um método para preparar pseudo-ilhotas. Além disso, a presente invenção também refere-se a métodos para tratar diabetes e distúrbios relacionados com diabetes por administração de compostos identificados pelos métodos descritos neste relatório.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36672802P | 2002-03-22 | 2002-03-22 | |
PCT/US2003/008712 WO2003082189A2 (en) | 2002-03-22 | 2003-03-21 | Method for producing pseudo islets |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0308753A true BR0308753A (pt) | 2005-01-11 |
Family
ID=28675278
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0308753-0A BR0308753A (pt) | 2002-03-22 | 2003-03-21 | Método para produzir pseudo-ilhotas |
Country Status (12)
Country | Link |
---|---|
US (1) | US20040005299A1 (pt) |
EP (1) | EP1490474A4 (pt) |
JP (1) | JP2005527203A (pt) |
KR (1) | KR20050000375A (pt) |
CN (1) | CN1643134A (pt) |
AU (1) | AU2003215023A1 (pt) |
BR (1) | BR0308753A (pt) |
CA (1) | CA2474512A1 (pt) |
MX (1) | MXPA04007064A (pt) |
PL (1) | PL372313A1 (pt) |
WO (1) | WO2003082189A2 (pt) |
ZA (1) | ZA200408436B (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2574424A1 (en) * | 2004-07-28 | 2006-02-02 | F. Hoffmann-La Roche Ag | Insulin promoter factor 1 as target/marker of beta cell failure |
EP2630233B1 (en) * | 2010-10-22 | 2017-03-22 | Lifeline Scientific, Inc. | Cultured pancreas islets |
JP2016202172A (ja) * | 2015-04-16 | 2016-12-08 | 国立大学法人京都大学 | 疑似膵島の製造方法 |
CN109957539A (zh) * | 2017-12-14 | 2019-07-02 | 深圳先进技术研究院 | 一种人造胰岛组织及其制备和应用 |
CN109406769A (zh) * | 2018-09-28 | 2019-03-01 | 李军 | Akr在min6细胞中胰岛素分泌机制研究的应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5759830A (en) * | 1986-11-20 | 1998-06-02 | Massachusetts Institute Of Technology | Three-dimensional fibrous scaffold containing attached cells for producing vascularized tissue in vivo |
US6001360A (en) * | 1988-12-13 | 1999-12-14 | University Of Florida | Method and compositions for early detection and treatment of insulin dependent diabetes mellitus |
US6001387A (en) * | 1992-05-29 | 1999-12-14 | The Reguents Of The University Of California | Spin disk encapsulation apparatus and method of use |
US5510263A (en) * | 1993-04-05 | 1996-04-23 | Desmos, Inc. | Growth of pancreatic islet-like cell clusters |
US5876742A (en) * | 1994-01-24 | 1999-03-02 | The Regents Of The University Of California | Biological tissue transplant coated with stabilized multilayer alginate coating suitable for transplantation and method of preparation thereof |
IL113484A0 (en) * | 1994-04-28 | 1995-07-31 | Immunex Corp | Viral proteins pharmaceutical compositions containing them their preparation and use |
US5695998A (en) * | 1995-02-10 | 1997-12-09 | Purdue Research Foundation | Submucosa as a growth substrate for islet cells |
US5679565A (en) * | 1995-04-10 | 1997-10-21 | The Regents Of The University Of California | Method of preserving pancreatic islets |
AU6496996A (en) * | 1996-02-23 | 1997-09-10 | Circle Biomedical, Inc. | Novel artificial pancreas |
MY128450A (en) * | 2000-05-24 | 2007-02-28 | Upjohn Co | 1-(pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives |
US6864069B2 (en) * | 2001-10-05 | 2005-03-08 | Bayer Pharmaceuticals Corporation | Peptides acting as both GLP-1 receptor agonists and glucagon receptor antagonists and their pharmacological methods of use |
-
2003
- 2003-03-21 CA CA002474512A patent/CA2474512A1/en not_active Abandoned
- 2003-03-21 PL PL03372313A patent/PL372313A1/xx not_active Application Discontinuation
- 2003-03-21 JP JP2003579732A patent/JP2005527203A/ja not_active Withdrawn
- 2003-03-21 CN CNA038067404A patent/CN1643134A/zh active Pending
- 2003-03-21 AU AU2003215023A patent/AU2003215023A1/en not_active Abandoned
- 2003-03-21 BR BR0308753-0A patent/BR0308753A/pt not_active IP Right Cessation
- 2003-03-21 WO PCT/US2003/008712 patent/WO2003082189A2/en not_active Application Discontinuation
- 2003-03-21 KR KR10-2004-7014880A patent/KR20050000375A/ko not_active Application Discontinuation
- 2003-03-21 EP EP03711665A patent/EP1490474A4/en not_active Withdrawn
- 2003-03-21 US US10/394,902 patent/US20040005299A1/en not_active Abandoned
- 2003-03-21 MX MXPA04007064A patent/MXPA04007064A/es unknown
-
2004
- 2004-10-19 ZA ZA200408436A patent/ZA200408436B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO2003082189A3 (en) | 2003-11-27 |
US20040005299A1 (en) | 2004-01-08 |
ZA200408436B (en) | 2005-10-19 |
PL372313A1 (en) | 2005-07-11 |
AU2003215023A1 (en) | 2003-10-13 |
CA2474512A1 (en) | 2003-10-09 |
CN1643134A (zh) | 2005-07-20 |
JP2005527203A (ja) | 2005-09-15 |
EP1490474A4 (en) | 2005-05-04 |
EP1490474A2 (en) | 2004-12-29 |
MXPA04007064A (es) | 2004-10-29 |
WO2003082189A2 (en) | 2003-10-09 |
KR20050000375A (ko) | 2005-01-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A, 5A,6A E 7A ANUIDADES |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2051 DE 27/04/2010. |