CL2021001541A1 - Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista de péptido de tlr para tratamiento de cáncer colorrectal (divisional de la solicitud no. 201900694) - Google Patents
Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista de péptido de tlr para tratamiento de cáncer colorrectal (divisional de la solicitud no. 201900694)Info
- Publication number
- CL2021001541A1 CL2021001541A1 CL2021001541A CL2021001541A CL2021001541A1 CL 2021001541 A1 CL2021001541 A1 CL 2021001541A1 CL 2021001541 A CL2021001541 A CL 2021001541A CL 2021001541 A CL2021001541 A CL 2021001541A CL 2021001541 A1 CL2021001541 A1 CL 2021001541A1
- Authority
- CL
- Chile
- Prior art keywords
- treatment
- colorectal cancer
- cell
- divisional
- cargo
- Prior art date
Links
- 206010009944 Colon cancer Diseases 0.000 title abstract 3
- 208000001333 Colorectal Neoplasms Diseases 0.000 title abstract 3
- 108010051109 Cell-Penetrating Peptides Proteins 0.000 title abstract 2
- 102000020313 Cell-Penetrating Peptides Human genes 0.000 title abstract 2
- 229940122985 Peptide agonist Drugs 0.000 title 1
- 230000002265 prevention Effects 0.000 abstract 2
- 239000000556 agonist Substances 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
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Abstract
La presente invención proporciona un complejo novedoso para el uso en la prevención y/o tratamiento de cáncer colorrectal, el complejo que comprende a) un péptido penetrante de células, b) al menos un antígeno o epítopo antigénico, y c) al menos un agonista de péptido de TLR, en donde los componentes a) – c) se ligan covalentemente. En particular, se proporcionan composiciones para el uso en la prevención y/o tratamiento de cáncer colorrectal, tal como en composiciones farmacéuticas y vacunas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP2016072475 | 2016-09-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2021001541A1 true CL2021001541A1 (es) | 2022-02-04 |
Family
ID=60037562
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2019000694A CL2019000694A1 (es) | 2016-09-21 | 2019-03-18 | Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista de péptido de tlr para tratamiento de cáncer colorrectal. |
CL2021001541A CL2021001541A1 (es) | 2016-09-21 | 2021-06-11 | Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista de péptido de tlr para tratamiento de cáncer colorrectal (divisional de la solicitud no. 201900694) |
CL2023002252A CL2023002252A1 (es) | 2016-09-21 | 2023-07-31 | Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2019000694A CL2019000694A1 (es) | 2016-09-21 | 2019-03-18 | Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista de péptido de tlr para tratamiento de cáncer colorrectal. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2023002252A CL2023002252A1 (es) | 2016-09-21 | 2023-07-31 | Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista |
Country Status (11)
Country | Link |
---|---|
US (3) | US20190255165A1 (es) |
EP (1) | EP3515476B1 (es) |
JP (1) | JP7346291B2 (es) |
KR (2) | KR20190057345A (es) |
CN (1) | CN109963585A (es) |
AU (1) | AU2017331949A1 (es) |
CA (1) | CA3031170A1 (es) |
CL (3) | CL2019000694A1 (es) |
IL (1) | IL265479B (es) |
MX (1) | MX2019002968A (es) |
WO (1) | WO2018055060A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP7346291B2 (ja) * | 2016-09-21 | 2023-09-19 | アマル セラピューティクス エスエー | 癌を治療するための細胞透過性ペプチド、マルチエピトープ、及びtlrペプチドアゴニストを含む融合体 |
US11945850B2 (en) * | 2018-09-17 | 2024-04-02 | Immatics Biotechnologies Gmbh | B*44 restricted peptides for use in immunotherapy against cancers and related methods |
WO2020252039A1 (en) * | 2019-06-12 | 2020-12-17 | Biontech Us Inc. | Neoantigen compositions and uses thereof |
CN110448689A (zh) * | 2019-08-06 | 2019-11-15 | 太仓美诺恒康生物技术有限公司 | mRNA疫苗及其试剂盒、应用 |
TW202214303A (zh) | 2020-05-19 | 2022-04-16 | 德商百靈佳殷格翰國際股份有限公司 | 用於癌症治療之結合分子 |
JP2023545178A (ja) * | 2020-10-14 | 2023-10-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Stingアゴニストと、細胞透過性ペプチド、カーゴ、及びtlrペプチドアゴニストを含む複合体との組合せ |
CN113480666B (zh) * | 2021-08-13 | 2024-01-26 | 郑州伊美诺生物技术有限公司 | Ca153融合蛋白及其制备方法和ca153检测质控品或校准品 |
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US20220305101A1 (en) | 2022-09-29 |
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CA3031170A1 (en) | 2018-03-29 |
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RU2019111160A (ru) | 2020-10-22 |
RU2019111160A3 (es) | 2021-01-19 |
AU2017331949A1 (en) | 2019-01-31 |
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US20190255165A1 (en) | 2019-08-22 |
WO2018055060A1 (en) | 2018-03-29 |
IL265479A (en) | 2019-05-30 |
KR20230131498A (ko) | 2023-09-13 |
IL265479B (en) | 2022-09-01 |
JP7346291B2 (ja) | 2023-09-19 |
CN109963585A (zh) | 2019-07-02 |
MX2019002968A (es) | 2019-10-15 |
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