CL2023002252A1 - Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista - Google Patents

Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista

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Publication number
CL2023002252A1
CL2023002252A1 CL2023002252A CL2023002252A CL2023002252A1 CL 2023002252 A1 CL2023002252 A1 CL 2023002252A1 CL 2023002252 A CL2023002252 A CL 2023002252A CL 2023002252 A CL2023002252 A CL 2023002252A CL 2023002252 A1 CL2023002252 A1 CL 2023002252A1
Authority
CL
Chile
Prior art keywords
agonist
cargo
penetrating peptide
cell penetrating
novel complex
Prior art date
Application number
CL2023002252A
Other languages
English (en)
Inventor
Derouazi Madiha
Belnoue Elodie
Original Assignee
Amal Therapeutics Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amal Therapeutics Sa filed Critical Amal Therapeutics Sa
Publication of CL2023002252A1 publication Critical patent/CL2023002252A1/es

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
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  • Pregnancy & Childbirth (AREA)
  • Developmental Biology & Embryology (AREA)
  • Vascular Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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Abstract

La presente invención proporciona un complejo novedoso para el uso en la prevención y/o tratamiento de cáncer colorrectal, el complejo que comprende a) un péptido penetrante de células, b) al menos un antígeno o epítopo antigénico, y c) al menos un agonista de péptido de tlr, en donde los componentes a) c) se ligan covalentemente. en particular, se proporcionan composiciones para el uso en la prevención y/o tratamiento de cáncer colorrectal, tal como en composiciones farmacéuticas y vacunas.
CL2023002252A 2016-09-21 2023-07-31 Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista CL2023002252A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP2016072475 2016-09-21

Publications (1)

Publication Number Publication Date
CL2023002252A1 true CL2023002252A1 (es) 2024-03-01

Family

ID=60037562

Family Applications (3)

Application Number Title Priority Date Filing Date
CL2019000694A CL2019000694A1 (es) 2016-09-21 2019-03-18 Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista de péptido de tlr para tratamiento de cáncer colorrectal.
CL2021001541A CL2021001541A1 (es) 2016-09-21 2021-06-11 Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista de péptido de tlr para tratamiento de cáncer colorrectal (divisional de la solicitud no. 201900694)
CL2023002252A CL2023002252A1 (es) 2016-09-21 2023-07-31 Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CL2019000694A CL2019000694A1 (es) 2016-09-21 2019-03-18 Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista de péptido de tlr para tratamiento de cáncer colorrectal.
CL2021001541A CL2021001541A1 (es) 2016-09-21 2021-06-11 Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista de péptido de tlr para tratamiento de cáncer colorrectal (divisional de la solicitud no. 201900694)

Country Status (13)

Country Link
US (3) US20190255165A1 (es)
EP (1) EP3515476B1 (es)
JP (1) JP7346291B2 (es)
KR (2) KR20230131498A (es)
CN (1) CN109963585B (es)
AU (1) AU2017331949A1 (es)
CA (1) CA3031170A1 (es)
CL (3) CL2019000694A1 (es)
DK (1) DK3515476T3 (es)
IL (1) IL265479B (es)
MX (1) MX2019002968A (es)
PL (1) PL3515476T3 (es)
WO (1) WO2018055060A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230131498A (ko) * 2016-09-21 2023-09-13 아말 테라퓨틱스 에스에이 암 치료를 위한, 세포 투과 펩타이드, 멀티 에피토프 및 tlr 펩타이드 작용제를 포함하는 융합체
US11945850B2 (en) * 2018-09-17 2024-04-02 Immatics Biotechnologies Gmbh B*44 restricted peptides for use in immunotherapy against cancers and related methods
CA3141084A1 (en) * 2019-06-12 2020-12-17 Vikram JUNEJA Neoantigen compositions and uses thereof
CN110448689A (zh) * 2019-08-06 2019-11-15 太仓美诺恒康生物技术有限公司 mRNA疫苗及其试剂盒、应用
EP3827840A1 (en) * 2019-11-29 2021-06-02 Academisch Ziekenhuis Leiden h.o.d.n. LUMC Teipp peptide variant and uses thereof
AU2021276332A1 (en) 2020-05-19 2022-11-17 Boehringer Ingelheim International Gmbh Binding molecules for the treatment of cancer
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