CL2019000694A1 - Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista de péptido de tlr para tratamiento de cáncer colorrectal. - Google Patents
Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista de péptido de tlr para tratamiento de cáncer colorrectal.Info
- Publication number
- CL2019000694A1 CL2019000694A1 CL2019000694A CL2019000694A CL2019000694A1 CL 2019000694 A1 CL2019000694 A1 CL 2019000694A1 CL 2019000694 A CL2019000694 A CL 2019000694A CL 2019000694 A CL2019000694 A CL 2019000694A CL 2019000694 A1 CL2019000694 A1 CL 2019000694A1
- Authority
- CL
- Chile
- Prior art keywords
- treatment
- loading
- colorectal cancer
- peptide
- cell penetrating
- Prior art date
Links
- 108010051109 Cell-Penetrating Peptides Proteins 0.000 title 1
- 102000020313 Cell-Penetrating Peptides Human genes 0.000 title 1
- 206010009944 Colon cancer Diseases 0.000 title 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 title 1
- 229940122985 Peptide agonist Drugs 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000000149 penetrating effect Effects 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
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- Oncology (AREA)
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- Pregnancy & Childbirth (AREA)
- Developmental Biology & Embryology (AREA)
- Vascular Medicine (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
LA PRESENTE INVENCIÓN PROPORCIONA UN COMPLEJO NOVEDOSO PARA EL USO EN LA PREVENCIÓN Y/O TRATAMIENTO DE CÁNCER COLORRECTAL, EL COMPLEJO QUE COMPRENDE A) UN PÉPTIDO PENETRANTE DE CÉLULAS, B) AL MENOS UN ANTÍGENO O EPÍTOPO ANTIGÉNICO, Y C) AL MENOS UN AGONISTA DE PÉPTIDO DE TLR, EN DONDE LOS COMPONENTES A) – C) SE LIGAN COVALENTEMENTE. EN PARTICULAR, SE PROPORCIONAN COMPOSICIONES PARA EL USO EN LA PREVENCIÓN Y/O TRATAMIENTO DE CÁNCER COLORRECTAL, TAL COMO EN COMPOSICIONES FARMACÉUTICAS Y VACUNAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP2016072475 | 2016-09-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2019000694A1 true CL2019000694A1 (es) | 2019-06-07 |
Family
ID=60037562
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2019000694A CL2019000694A1 (es) | 2016-09-21 | 2019-03-18 | Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista de péptido de tlr para tratamiento de cáncer colorrectal. |
CL2021001541A CL2021001541A1 (es) | 2016-09-21 | 2021-06-11 | Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista de péptido de tlr para tratamiento de cáncer colorrectal (divisional de la solicitud no. 201900694) |
CL2023002252A CL2023002252A1 (es) | 2016-09-21 | 2023-07-31 | Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2021001541A CL2021001541A1 (es) | 2016-09-21 | 2021-06-11 | Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista de péptido de tlr para tratamiento de cáncer colorrectal (divisional de la solicitud no. 201900694) |
CL2023002252A CL2023002252A1 (es) | 2016-09-21 | 2023-07-31 | Un complejo novedoso que comprende un péptido penetrante de células, una carga y un agonista |
Country Status (13)
Country | Link |
---|---|
US (3) | US20190255165A1 (es) |
EP (1) | EP3515476B1 (es) |
JP (1) | JP7346291B2 (es) |
KR (2) | KR20230131498A (es) |
CN (1) | CN109963585B (es) |
AU (1) | AU2017331949A1 (es) |
CA (1) | CA3031170A1 (es) |
CL (3) | CL2019000694A1 (es) |
DK (1) | DK3515476T3 (es) |
IL (1) | IL265479B (es) |
MX (1) | MX2019002968A (es) |
PL (1) | PL3515476T3 (es) |
WO (1) | WO2018055060A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20230131498A (ko) * | 2016-09-21 | 2023-09-13 | 아말 테라퓨틱스 에스에이 | 암 치료를 위한, 세포 투과 펩타이드, 멀티 에피토프 및 tlr 펩타이드 작용제를 포함하는 융합체 |
US11945850B2 (en) * | 2018-09-17 | 2024-04-02 | Immatics Biotechnologies Gmbh | B*44 restricted peptides for use in immunotherapy against cancers and related methods |
CA3141084A1 (en) * | 2019-06-12 | 2020-12-17 | Vikram JUNEJA | Neoantigen compositions and uses thereof |
CN110448689A (zh) * | 2019-08-06 | 2019-11-15 | 太仓美诺恒康生物技术有限公司 | mRNA疫苗及其试剂盒、应用 |
EP3827840A1 (en) * | 2019-11-29 | 2021-06-02 | Academisch Ziekenhuis Leiden h.o.d.n. LUMC | Teipp peptide variant and uses thereof |
AU2021276332A1 (en) | 2020-05-19 | 2022-11-17 | Boehringer Ingelheim International Gmbh | Binding molecules for the treatment of cancer |
WO2022079175A1 (en) * | 2020-10-14 | 2022-04-21 | Boehringer Ingelheim International Gmbh | Combination of a sting agonist and a complex comprising a cell penetrating peptide, a cargo and a tlr peptide agonist |
CN113480666B (zh) * | 2021-08-13 | 2024-01-26 | 郑州伊美诺生物技术有限公司 | Ca153融合蛋白及其制备方法和ca153检测质控品或校准品 |
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US20220305101A1 (en) | 2022-09-29 |
US11338027B2 (en) | 2022-05-24 |
CA3031170A1 (en) | 2018-03-29 |
CL2023002252A1 (es) | 2024-03-01 |
KR20190057345A (ko) | 2019-05-28 |
DK3515476T3 (da) | 2024-09-02 |
EP3515476A1 (en) | 2019-07-31 |
CN109963585A (zh) | 2019-07-02 |
JP2019528693A (ja) | 2019-10-17 |
AU2017331949A1 (en) | 2019-01-31 |
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