CL2018001556A1 - Receptores de antígenos quiméricos (car) de bcma. (solicitud divisional 201701515) - Google Patents

Receptores de antígenos quiméricos (car) de bcma. (solicitud divisional 201701515)

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Publication number
CL2018001556A1
CL2018001556A1 CL2018001556A CL2018001556A CL2018001556A1 CL 2018001556 A1 CL2018001556 A1 CL 2018001556A1 CL 2018001556 A CL2018001556 A CL 2018001556A CL 2018001556 A CL2018001556 A CL 2018001556A CL 2018001556 A1 CL2018001556 A1 CL 2018001556A1
Authority
CL
Chile
Prior art keywords
car
divisional application
antigen receptors
bcma chimeric
bcma
Prior art date
Application number
CL2018001556A
Other languages
English (en)
Inventor
Richard Morgan
Kevin Friedman
Original Assignee
Bluebird Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bluebird Bio Inc filed Critical Bluebird Bio Inc
Publication of CL2018001556A1 publication Critical patent/CL2018001556A1/es

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    • A61K39/0011Cancer antigens
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • A61K39/4611T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • AHUMAN NECESSITIES
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    • A61K39/4631Chimeric Antigen Receptors [CAR]
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    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643Vertebrate antigens
    • A61K39/4644Cancer antigens
    • A61K39/464402Receptors, cell surface antigens or cell surface determinants
    • A61K39/464416Receptors for cytokines
    • A61K39/464417Receptors for tumor necrosis factors [TNF], e.g. lymphotoxin receptor [LTR], CD30
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
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    • C12N2740/00Reverse transcribing RNA viruses
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    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041Use of virus, viral particle or viral elements as a vector
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/15Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
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    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

LA INVENCIÓN BRINDA COMPOSICIONES MEJORADAS PARA TERAPIAS CON CÉLULAS T ADOPTIVAS PARA AFECCIONES RELACIONADAS CON CÉLULAS B.
CL2018001556A 2014-12-12 2018-06-12 Receptores de antígenos quiméricos (car) de bcma. (solicitud divisional 201701515) CL2018001556A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462091419P 2014-12-12 2014-12-12
US201562200505P 2015-08-03 2015-08-03

Publications (1)

Publication Number Publication Date
CL2018001556A1 true CL2018001556A1 (es) 2018-07-20

Family

ID=56108356

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2017001515A CL2017001515A1 (es) 2014-12-12 2017-06-12 Receptores de antígeno químericos bcma
CL2018001556A CL2018001556A1 (es) 2014-12-12 2018-06-12 Receptores de antígenos quiméricos (car) de bcma. (solicitud divisional 201701515)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CL2017001515A CL2017001515A1 (es) 2014-12-12 2017-06-12 Receptores de antígeno químericos bcma

Country Status (29)

Country Link
US (10) US10383929B2 (es)
EP (4) EP3230321B1 (es)
JP (4) JP6671370B2 (es)
KR (2) KR102584938B1 (es)
CN (2) CN107207598B (es)
AU (2) AU2015360845B2 (es)
BR (1) BR112017012502B1 (es)
CA (1) CA2970466A1 (es)
CL (2) CL2017001515A1 (es)
CO (1) CO2017006808A2 (es)
CY (2) CY1122528T1 (es)
DK (2) DK3628687T3 (es)
EA (1) EA036379B1 (es)
EC (1) ECSP17044494A (es)
ES (2) ES2895640T3 (es)
HK (1) HK1245801B (es)
HR (2) HRP20211648T1 (es)
HU (2) HUE046815T2 (es)
IL (2) IL252783B (es)
LT (2) LT3230321T (es)
MX (2) MX2017007575A (es)
NZ (1) NZ733025A (es)
PL (2) PL3230321T3 (es)
PT (2) PT3628687T (es)
RS (2) RS62527B1 (es)
SG (2) SG11201704727WA (es)
SI (2) SI3230321T1 (es)
WO (1) WO2016094304A2 (es)
ZA (1) ZA201704059B (es)

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