SG10202013144UA - Bcma chimeric antigen receptors - Google Patents

Bcma chimeric antigen receptors

Info

Publication number
SG10202013144UA
SG10202013144UA SG10202013144UA SG10202013144UA SG10202013144UA SG 10202013144U A SG10202013144U A SG 10202013144UA SG 10202013144U A SG10202013144U A SG 10202013144UA SG 10202013144U A SG10202013144U A SG 10202013144UA SG 10202013144U A SG10202013144U A SG 10202013144UA
Authority
SG
Singapore
Prior art keywords
chimeric antigen
antigen receptors
bcma chimeric
bcma
receptors
Prior art date
Application number
SG10202013144UA
Inventor
Richard Morgan
Kevin Friedman
Original Assignee
Bluebird Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bluebird Bio Inc filed Critical Bluebird Bio Inc
Publication of SG10202013144UA publication Critical patent/SG10202013144UA/en

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    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
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    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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    • A61K39/46—Cellular immunotherapy
    • A61K39/463—Cellular immunotherapy characterised by recombinant expression
    • A61K39/4631—Chimeric Antigen Receptors [CAR]
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    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K2317/622—Single chain antibody (scFv)
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
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SG10202013144UA 2014-12-12 2015-12-07 Bcma chimeric antigen receptors SG10202013144UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462091419P 2014-12-12 2014-12-12
US201562200505P 2015-08-03 2015-08-03

Publications (1)

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SG10202013144UA true SG10202013144UA (en) 2021-02-25

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US (10) US10383929B2 (en)
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JP (4) JP6671370B2 (en)
KR (2) KR102584938B1 (en)
CN (2) CN112358551B (en)
AU (2) AU2015360845B2 (en)
BR (1) BR112017012502B1 (en)
CA (1) CA2970466A1 (en)
CL (2) CL2017001515A1 (en)
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DK (2) DK3230321T3 (en)
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HR (2) HRP20211648T1 (en)
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IL (2) IL252783B (en)
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PL (2) PL3230321T3 (en)
PT (2) PT3628687T (en)
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SI (2) SI3628687T1 (en)
WO (1) WO2016094304A2 (en)
ZA (1) ZA201704059B (en)

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