CL2015000717A1 - Compuestos derivados de piridinonas biciclicas y sus sales; composicion farmaceutica que los comprende; y su uso para el tratamiento de la neurodegeneracion y trastornos psiquiatricos, que incluyen enfermedad de alzheimer o enfermedad de niemann-pick tipo c. - Google Patents

Compuestos derivados de piridinonas biciclicas y sus sales; composicion farmaceutica que los comprende; y su uso para el tratamiento de la neurodegeneracion y trastornos psiquiatricos, que incluyen enfermedad de alzheimer o enfermedad de niemann-pick tipo c.

Info

Publication number
CL2015000717A1
CL2015000717A1 CL2015000717A CL2015000717A CL2015000717A1 CL 2015000717 A1 CL2015000717 A1 CL 2015000717A1 CL 2015000717 A CL2015000717 A CL 2015000717A CL 2015000717 A CL2015000717 A CL 2015000717A CL 2015000717 A1 CL2015000717 A1 CL 2015000717A1
Authority
CL
Chile
Prior art keywords
disease
niemann
neurodegeneration
salts
treatment
Prior art date
Application number
CL2015000717A
Other languages
English (en)
Spanish (es)
Inventor
Patrick Robert Verhoest
Antonia Friederike Stepan
Ende Christopher William Am
Michael Eric Green
Douglas Scott Johnson
Gregory Wayne Kauffman
Christopher John O'donnell
Nandini Chaturbhai Patel
Martin Youngjin Petterson
Cory Michael Stiff
Chakrapani Subramanyam
Tuan Phong Tran
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CL2015000717A1 publication Critical patent/CL2015000717A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epidemiology (AREA)
CL2015000717A 2012-09-21 2015-03-20 Compuestos derivados de piridinonas biciclicas y sus sales; composicion farmaceutica que los comprende; y su uso para el tratamiento de la neurodegeneracion y trastornos psiquiatricos, que incluyen enfermedad de alzheimer o enfermedad de niemann-pick tipo c. CL2015000717A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261703969P 2012-09-21 2012-09-21

Publications (1)

Publication Number Publication Date
CL2015000717A1 true CL2015000717A1 (es) 2015-06-19

Family

ID=49585452

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015000717A CL2015000717A1 (es) 2012-09-21 2015-03-20 Compuestos derivados de piridinonas biciclicas y sus sales; composicion farmaceutica que los comprende; y su uso para el tratamiento de la neurodegeneracion y trastornos psiquiatricos, que incluyen enfermedad de alzheimer o enfermedad de niemann-pick tipo c.

Country Status (46)

Country Link
US (3) US8916564B2 (en:Method)
EP (1) EP2897956B1 (en:Method)
JP (1) JP5844018B2 (en:Method)
KR (1) KR101725696B1 (en:Method)
CN (1) CN104662021B (en:Method)
AP (1) AP2015008277A0 (en:Method)
AR (1) AR092628A1 (en:Method)
AU (1) AU2013319845B2 (en:Method)
BR (1) BR112015006436A2 (en:Method)
CA (1) CA2882386C (en:Method)
CL (1) CL2015000717A1 (en:Method)
CR (1) CR20150053A (en:Method)
CU (1) CU20150021A7 (en:Method)
CY (1) CY1118662T1 (en:Method)
DK (1) DK2897956T3 (en:Method)
DO (1) DOP2015000069A (en:Method)
EA (1) EA026668B1 (en:Method)
EC (1) ECSP15015594A (en:Method)
ES (1) ES2609987T3 (en:Method)
GE (1) GEP201706659B (en:Method)
GT (1) GT201500069A (en:Method)
HR (1) HRP20161558T1 (en:Method)
HU (1) HUE031248T2 (en:Method)
IL (1) IL237163A (en:Method)
IN (1) IN2015DN01119A (en:Method)
LT (1) LT2897956T (en:Method)
MA (1) MA37886B1 (en:Method)
MD (1) MD4583B1 (en:Method)
ME (1) ME02571B (en:Method)
MX (1) MX360599B (en:Method)
MY (1) MY181891A (en:Method)
NI (1) NI201500038A (en:Method)
NZ (1) NZ704863A (en:Method)
PE (1) PE20150686A1 (en:Method)
PH (1) PH12015500376B1 (en:Method)
PL (1) PL2897956T3 (en:Method)
PT (1) PT2897956T (en:Method)
RS (1) RS55426B1 (en:Method)
SG (1) SG11201501074WA (en:Method)
SI (1) SI2897956T1 (en:Method)
TN (1) TN2015000084A1 (en:Method)
TW (1) TWI500616B (en:Method)
UA (1) UA110688C2 (en:Method)
UY (1) UY35039A (en:Method)
WO (1) WO2014045156A1 (en:Method)
ZA (1) ZA201501195B (en:Method)

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CN113402490B (zh) * 2021-03-29 2023-01-03 白银京宇新药业有限公司 一种1，2，6，7-四氢-8H-茚并[5，4-b]呋喃-8-酮的制备方法
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