CL2012002737A1 - Anticuerpo anti-cd40 humanizado; polinucleótido que lo codifica; composición farmacéutica que comprende dicho anticuerpo; y su uso para bloquear una respuesta inmunitaria mediada por cd40 humana. - Google Patents
Anticuerpo anti-cd40 humanizado; polinucleótido que lo codifica; composición farmacéutica que comprende dicho anticuerpo; y su uso para bloquear una respuesta inmunitaria mediada por cd40 humana.Info
- Publication number
- CL2012002737A1 CL2012002737A1 CL2012002737A CL2012002737A CL2012002737A1 CL 2012002737 A1 CL2012002737 A1 CL 2012002737A1 CL 2012002737 A CL2012002737 A CL 2012002737A CL 2012002737 A CL2012002737 A CL 2012002737A CL 2012002737 A1 CL2012002737 A1 CL 2012002737A1
- Authority
- CL
- Chile
- Prior art keywords
- antibody
- human
- block
- pharmaceutical composition
- immune response
- Prior art date
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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Abstract
Anticuerpo anti-CD40 humanizado; polinucleótido que lo codifica; composición farmacéutica que comprende dicho anticuerpo; y su uso para bloquear una respuesta inmunitaria mediada por CD40 humana.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31957410P | 2010-03-31 | 2010-03-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2012002737A1 true CL2012002737A1 (es) | 2013-02-15 |
Family
ID=44169124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2012002737A CL2012002737A1 (es) | 2010-03-31 | 2012-09-28 | Anticuerpo anti-cd40 humanizado; polinucleótido que lo codifica; composición farmacéutica que comprende dicho anticuerpo; y su uso para bloquear una respuesta inmunitaria mediada por cd40 humana. |
Country Status (38)
Country | Link |
---|---|
US (7) | US8591900B2 (es) |
EP (3) | EP3178851B1 (es) |
JP (2) | JP2013523130A (es) |
KR (1) | KR101760242B1 (es) |
CN (1) | CN102918063B (es) |
AP (1) | AP4082A (es) |
AR (1) | AR081750A1 (es) |
AU (1) | AU2011235214B2 (es) |
BR (1) | BR112012024713B1 (es) |
CA (1) | CA2794332C (es) |
CL (1) | CL2012002737A1 (es) |
CO (1) | CO6612271A2 (es) |
CY (2) | CY1120181T1 (es) |
DK (2) | DK2796467T3 (es) |
EA (1) | EA031872B1 (es) |
EC (1) | ECSP12012221A (es) |
ES (2) | ES2807217T3 (es) |
GE (1) | GEP20166486B (es) |
HR (2) | HRP20180542T1 (es) |
HU (2) | HUE049849T2 (es) |
IL (2) | IL221639A (es) |
LT (2) | LT2796467T (es) |
MA (1) | MA34091B1 (es) |
MX (2) | MX340140B (es) |
MY (2) | MY155950A (es) |
NO (1) | NO2796467T3 (es) |
NZ (1) | NZ602020A (es) |
PE (1) | PE20130159A1 (es) |
PL (2) | PL2796467T3 (es) |
PT (2) | PT2796467T (es) |
RS (2) | RS60612B1 (es) |
SG (1) | SG183947A1 (es) |
SI (2) | SI3178851T1 (es) |
TN (1) | TN2012000462A1 (es) |
TW (1) | TWI494126B (es) |
UA (1) | UA107827C2 (es) |
UY (1) | UY33306A (es) |
WO (1) | WO2011123489A2 (es) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9765150B2 (en) | 2011-10-13 | 2017-09-19 | Bristol-Myers Squibb Company | Antibody polypeptides that antagonize CD40L |
US11136406B2 (en) | 2011-04-21 | 2021-10-05 | Bristol-Myers Squibb Company | Methods of treating immune diseases by administering antibody polypeptides that antagonize CD40 |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA031872B1 (ru) * | 2010-03-31 | 2019-03-29 | Бёрингер Ингельхайм Интернациональ Гмбх | Гуманизированное антитело к cd40, его применение, фармацевтическая композиция, содержащая это антитело, и выделенный полинуклеотид, кодирующий его |
EP2625292B1 (en) | 2010-10-07 | 2018-12-05 | The General Hospital Corporation | Biomarkers of cancer |
US9987356B2 (en) | 2011-03-11 | 2018-06-05 | Beth Israel Deaconess Medical Center, Inc. | Anti-CD40 antibodies and methods of administering thereof |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11136406B2 (en) | 2011-04-21 | 2021-10-05 | Bristol-Myers Squibb Company | Methods of treating immune diseases by administering antibody polypeptides that antagonize CD40 |
US9765150B2 (en) | 2011-10-13 | 2017-09-19 | Bristol-Myers Squibb Company | Antibody polypeptides that antagonize CD40L |
US10196451B2 (en) | 2011-10-13 | 2019-02-05 | Bristol-Myers Squibb Company | Methods of treating immune diseases by administering antibody polypeptides that specifically bind CD40L |
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