CL2009001065A1 - Compuestos derivados de 4-pirimidinil-1,3-tiazol (o 1,3-oxazol) sulfonamidas sustituidas, inhibidores de quinasas raf; composicion farmaceutica; procedimiento de preparacion; y uso para tratar un neoplasma susceptible, seleccionado de adenocarcinoma de barret, carcinomas del tracto biliar y cancer de seno, entre otros. - Google Patents
Compuestos derivados de 4-pirimidinil-1,3-tiazol (o 1,3-oxazol) sulfonamidas sustituidas, inhibidores de quinasas raf; composicion farmaceutica; procedimiento de preparacion; y uso para tratar un neoplasma susceptible, seleccionado de adenocarcinoma de barret, carcinomas del tracto biliar y cancer de seno, entre otros.Info
- Publication number
- CL2009001065A1 CL2009001065A1 CL2009001065A CL2009001065A CL2009001065A1 CL 2009001065 A1 CL2009001065 A1 CL 2009001065A1 CL 2009001065 A CL2009001065 A CL 2009001065A CL 2009001065 A CL2009001065 A CL 2009001065A CL 2009001065 A1 CL2009001065 A1 CL 2009001065A1
- Authority
- CL
- Chile
- Prior art keywords
- pyrimidinyl
- sulfonamides
- barret
- carcinomas
- adenocarcinoma
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Compuestos derivados de 4-pirimidinil-1,3-tiazol sulfonamidas o 4-pirimidinil-1,3-oxazol sulfonamidas sustituidas; composición farmacéutica que los comprende; proceso para prepararlos; y su uso para tratar un neoplasma susceptible seleccionado de adenocarcinoma de barret, carcinomas del tracto biliar y cáncer de seno, entre otros.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5074408P | 2008-05-06 | 2008-05-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2009001065A1 true CL2009001065A1 (es) | 2010-12-31 |
Family
ID=41265326
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2009001065A CL2009001065A1 (es) | 2008-05-06 | 2009-05-04 | Compuestos derivados de 4-pirimidinil-1,3-tiazol (o 1,3-oxazol) sulfonamidas sustituidas, inhibidores de quinasas raf; composicion farmaceutica; procedimiento de preparacion; y uso para tratar un neoplasma susceptible, seleccionado de adenocarcinoma de barret, carcinomas del tracto biliar y cancer de seno, entre otros. |
Country Status (35)
Country | Link |
---|---|
US (6) | US8415345B2 (es) |
EP (2) | EP3106462A1 (es) |
JP (1) | JP5426664B2 (es) |
KR (1) | KR101628746B1 (es) |
CN (1) | CN102083312B (es) |
AR (1) | AR071617A1 (es) |
AU (1) | AU2009244491B2 (es) |
BR (1) | BRPI0912541B8 (es) |
CA (1) | CA2723396C (es) |
CL (1) | CL2009001065A1 (es) |
CO (1) | CO6321189A2 (es) |
CY (1) | CY1117615T1 (es) |
DK (1) | DK2282636T3 (es) |
DO (1) | DOP2010000326A (es) |
EA (1) | EA019349B1 (es) |
ES (1) | ES2576684T3 (es) |
HK (1) | HK1147907A1 (es) |
HR (1) | HRP20160447T1 (es) |
HU (1) | HUE028820T2 (es) |
IL (1) | IL209018A (es) |
JO (1) | JO3408B1 (es) |
MA (1) | MA32369B1 (es) |
MX (1) | MX2010012074A (es) |
MY (1) | MY155317A (es) |
NZ (1) | NZ588970A (es) |
PE (1) | PE20091952A1 (es) |
PL (1) | PL2282636T3 (es) |
RS (1) | RS54725B1 (es) |
SG (1) | SG190624A1 (es) |
SI (1) | SI2282636T1 (es) |
TW (1) | TWI432430B (es) |
UA (1) | UA103319C2 (es) |
UY (1) | UY31806A (es) |
WO (1) | WO2009137391A2 (es) |
ZA (1) | ZA201007960B (es) |
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