UY29360A1 - Nuevos derivados de pirazol, composiciones farmacéuticas que los contienen, procedimientos de preparación y aplicaciones. - Google Patents

Nuevos derivados de pirazol, composiciones farmacéuticas que los contienen, procedimientos de preparación y aplicaciones.

Info

Publication number
UY29360A1
UY29360A1 UY29360A UY29360A UY29360A1 UY 29360 A1 UY29360 A1 UY 29360A1 UY 29360 A UY29360 A UY 29360A UY 29360 A UY29360 A UY 29360A UY 29360 A1 UY29360 A1 UY 29360A1
Authority
UY
Uruguay
Prior art keywords
pharmaceutical compositions
pirazol
contain
applications
preparation procedures
Prior art date
Application number
UY29360A
Other languages
English (en)
Inventor
Audrey S Davies
Lamb Michelle
Lyne Paul
Wang Tao
Yu Dingwei
Mohr Peter
Wang Bin
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY29360A1 publication Critical patent/UY29360A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere compuestos novedosos que presentan la fórmula (I): y a sus composiciones farmacéuticas y métodos de utilización. Dichos compuestos novedosos proporcionan un tratamiento para el cáncer.
UY29360A 2005-02-04 2006-02-03 Nuevos derivados de pirazol, composiciones farmacéuticas que los contienen, procedimientos de preparación y aplicaciones. UY29360A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65005305P 2005-02-04 2005-02-04
US65332905P 2005-02-16 2005-02-16
US72163305P 2005-09-29 2005-09-29

Publications (1)

Publication Number Publication Date
UY29360A1 true UY29360A1 (es) 2006-10-02

Family

ID=36177856

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29360A UY29360A1 (es) 2005-02-04 2006-02-03 Nuevos derivados de pirazol, composiciones farmacéuticas que los contienen, procedimientos de preparación y aplicaciones.

Country Status (30)

Country Link
US (2) US8324252B2 (es)
EP (2) EP1846394B1 (es)
JP (1) JP5139084B2 (es)
KR (1) KR101302945B1 (es)
CN (1) CN101155800B (es)
AR (1) AR056184A1 (es)
AT (1) ATE530545T1 (es)
AU (1) AU2006210710B2 (es)
BR (1) BRPI0606793A8 (es)
CA (1) CA2595834C (es)
CY (2) CY1115078T1 (es)
DK (2) DK2383268T3 (es)
ES (2) ES2375735T3 (es)
HK (2) HK1114374A1 (es)
HR (1) HRP20110962T1 (es)
HU (1) HUE025671T2 (es)
IL (1) IL184674A (es)
ME (1) ME02645B (es)
MX (1) MX2007009437A (es)
MY (1) MY149512A (es)
NO (1) NO341112B1 (es)
NZ (1) NZ561145A (es)
PL (2) PL1846394T3 (es)
PT (2) PT2383268E (es)
RS (1) RS52061B (es)
SA (1) SA06270007B1 (es)
SI (2) SI1846394T1 (es)
TW (1) TWI370127B (es)
UY (1) UY29360A1 (es)
WO (1) WO2006082392A1 (es)

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JP5524491B2 (ja) * 2008-03-04 2014-06-18 石原産業株式会社 ３−アミノ−２−クロロ−６−トリフルオロメチルピリジンの製造方法
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EP3601267A1 (en) 2017-03-21 2020-02-05 Bayer Pharma Aktiengesellschaft 2-methyl-quinazolines
EP3781565A1 (en) 2018-04-18 2021-02-24 Bayer Pharma Aktiengesellschaft 2-methyl-aza-quinazolines
EA202192575A1 (ru) 2019-03-21 2022-01-14 Онксео Соединения dbait в сочетании с ингибиторами киназ для лечения рака
CN113727984B (zh) 2019-05-21 2024-03-15 浙江海正药业股份有限公司 大环类衍生物、及其制备方法和用途
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Also Published As

Publication number Publication date
JP2008528664A (ja) 2008-07-31
ES2375735T3 (es) 2012-03-05
BRPI0606793A8 (pt) 2018-03-13
SI1846394T1 (sl) 2012-06-29
CN101155800A (zh) 2008-04-02
PL2383268T3 (pl) 2016-02-29
KR101302945B1 (ko) 2013-09-06
MX2007009437A (es) 2007-08-16
ME02645B (me) 2012-04-30
ES2555063T3 (es) 2015-12-28
SA06270007B1 (ar) 2010-11-22
PL1846394T3 (pl) 2012-04-30
BRPI0606793A2 (pt) 2009-12-01
DK1846394T3 (da) 2012-01-16
EP1846394B1 (en) 2011-10-26
WO2006082392A1 (en) 2006-08-10
DK2383268T3 (en) 2015-09-14
NO20073791L (no) 2007-08-30
IL184674A0 (en) 2007-12-03
EP1846394A1 (en) 2007-10-24
HRP20110962T1 (hr) 2012-01-31
PT1846394E (pt) 2012-01-05
TWI370127B (en) 2012-08-11
AU2006210710A1 (en) 2006-08-10
AR056184A1 (es) 2007-09-26
ATE530545T1 (de) 2011-11-15
CN101155800B (zh) 2012-05-23
IL184674A (en) 2012-07-31
US20130090358A1 (en) 2013-04-11
CA2595834A1 (en) 2006-08-10
AU2006210710B2 (en) 2009-12-10
HK1114374A1 (en) 2008-10-31
CA2595834C (en) 2013-04-30
PT2383268E (pt) 2015-12-21
MY149512A (en) 2013-09-13
SI2383268T1 (sl) 2016-02-29
HUE025671T2 (en) 2016-04-28
HK1163677A1 (zh) 2012-09-14
RS52061B (en) 2012-04-30
NO341112B1 (no) 2017-08-28
CY1115078T1 (el) 2016-12-14
US20080139561A1 (en) 2008-06-12
KR20070107107A (ko) 2007-11-06
JP5139084B2 (ja) 2013-02-06
EP2383268B1 (en) 2015-09-02
EP2383268A1 (en) 2011-11-02
US8324252B2 (en) 2012-12-04
NZ561145A (en) 2011-02-25
US8835465B2 (en) 2014-09-16
CY1119077T1 (el) 2018-01-10

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