CA2716109C - Heteroaryl derivatives as cftr modulators - Google Patents

Heteroaryl derivatives as cftr modulators Download PDF

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Publication number
CA2716109C
CA2716109C CA2716109A CA2716109A CA2716109C CA 2716109 C CA2716109 C CA 2716109C CA 2716109 A CA2716109 A CA 2716109A CA 2716109 A CA2716109 A CA 2716109A CA 2716109 C CA2716109 C CA 2716109C
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compound
pharmaceutically acceptable
acceptable salt
disease
heteroaryl
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CA2716109A
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French (fr)
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CA2716109A1 (en
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Sara Hadida-Ruah
Mark Miller
Jinglan Zhou
Brian Bear
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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