CA2663083A1 - Modified human plasma polypeptide or fc scaffolds and their uses - Google Patents
Modified human plasma polypeptide or fc scaffolds and their uses Download PDFInfo
- Publication number
- CA2663083A1 CA2663083A1 CA002663083A CA2663083A CA2663083A1 CA 2663083 A1 CA2663083 A1 CA 2663083A1 CA 002663083 A CA002663083 A CA 002663083A CA 2663083 A CA2663083 A CA 2663083A CA 2663083 A1 CA2663083 A1 CA 2663083A1
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- polypeptide
- hpp
- amino acid
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Classifications
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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| US84321506P | 2006-09-08 | 2006-09-08 | |
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| US92848507P | 2007-05-08 | 2007-05-08 | |
| US60/928,485 | 2007-05-08 | ||
| PCT/US2007/019528 WO2008030558A2 (en) | 2006-09-08 | 2007-09-07 | Modified human plasma polypeptide or fc scaffolds and their uses |
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| CA2663083A1 true CA2663083A1 (en) | 2008-03-13 |
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| ATE534290T1 (de) | 2004-09-07 | 2011-12-15 | Velico Medical Inc | Apparat zur verlängerung der überlebensdauer von blutplättchen |
| EP1954304A4 (en) * | 2005-10-14 | 2010-03-10 | Zymequest Inc | COMPOSITIONS AND METHOD FOR EXTENDING THE LIFE OF PLATES |
| CA2630415A1 (en) * | 2005-10-20 | 2007-04-26 | The Scripps Research Institute | Fc labeling for immunostaining and immunotargeting |
| ES2507098T3 (es) | 2005-11-07 | 2014-10-14 | Indiana University Research And Technology Corporation | Análogos de glucagón que muestran solubilidad y estabilidad fisiológicas |
| CN101578102B (zh) * | 2007-01-05 | 2013-07-17 | 印第安纳大学研究及科技有限公司 | 在生理性pH缓冲液中显示增强的溶解性的胰高血糖素类似物 |
| CA2677932A1 (en) * | 2007-02-15 | 2008-08-21 | Indiana University Research And Technology Corporation | Glucagon/glp-1 receptor co-agonists |
| MX2010004298A (es) * | 2007-10-30 | 2010-05-03 | Univ Indiana Res & Tech Corp | Compuestos que exhiben actividad antagonista de glucagon y agonista de glp-1. |
| CN101983066B (zh) * | 2008-01-30 | 2016-06-29 | 印第安那大学科技研究公司 | 基于酯的胰岛素前药 |
| AU2009260301B2 (en) * | 2008-06-17 | 2015-09-03 | Indiana University Research And Technology Corporation | Glucagon analogs exhibiting enhanced solubility and stability in physiological pH buffers |
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| CA2729296A1 (en) * | 2008-06-17 | 2010-01-28 | Richard D. Dimarchi | Gip-based mixed agonists for treatment of metabolic disorders and obesity |
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| EP2376520B1 (en) | 2008-12-19 | 2014-02-12 | Indiana University Research&Technology Corporation | Insulin analogs |
| EP2376521B1 (en) | 2008-12-19 | 2016-04-13 | Indiana University Research and Technology Corporation | Amide-based insulin prodrugs |
| MX2011006527A (es) * | 2008-12-19 | 2011-08-17 | Univ Indiana Res & Tech Corp | Agentes medicinales unidos a dipeptido. |
| US8969288B2 (en) | 2008-12-19 | 2015-03-03 | Indiana University Research And Technology Corporation | Amide based glucagon and superfamily peptide prodrugs |
| DK2396347T3 (en) | 2009-02-11 | 2017-07-24 | Albumedix As | ALBUMIN VARIANTS AND CONJUGATES |
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| EP2443146B1 (en) | 2009-06-16 | 2016-10-05 | Indiana University Research And Technology Corporation | Gip receptor-active glucagon compounds |
| BR112012009450A2 (pt) | 2009-10-30 | 2017-05-23 | Novozymes Biopharma Dk As | variantes de albumina |
| US8703701B2 (en) | 2009-12-18 | 2014-04-22 | Indiana University Research And Technology Corporation | Glucagon/GLP-1 receptor co-agonists |
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2007
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- 2007-09-07 WO PCT/US2007/019528 patent/WO2008030558A2/en active Application Filing
- 2007-09-07 DK DK12196353.2T patent/DK2615108T3/en active
- 2007-09-07 JP JP2009527426A patent/JP5840345B2/ja not_active Expired - Fee Related
- 2007-09-07 CN CN201610346408.3A patent/CN106008699A/zh active Pending
- 2007-09-07 CN CN201410302933.6A patent/CN104193815A/zh active Pending
- 2007-09-07 EP EP07837882.5A patent/EP2069396B1/en active Active
- 2007-09-07 US US12/440,010 patent/US8618257B2/en active Active
- 2007-09-07 MX MX2009002523A patent/MX2009002523A/es active IP Right Grant
- 2007-09-07 KR KR1020097005245A patent/KR20090060294A/ko not_active Application Discontinuation
- 2007-09-07 CA CA002663083A patent/CA2663083A1/en not_active Abandoned
- 2007-09-07 EP EP12196353.2A patent/EP2615108B1/en active Active
- 2007-10-29 US US11/927,247 patent/US8053560B2/en not_active Expired - Fee Related
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- 2009-12-10 HK HK09111623.3A patent/HK1134302A1/zh not_active IP Right Cessation
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2011
- 2011-02-25 US US13/035,719 patent/US20110207914A1/en not_active Abandoned
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