CA2436832C - Crystal form of a cyclic depsipeptide having improved activity - Google Patents
Crystal form of a cyclic depsipeptide having improved activity Download PDFInfo
- Publication number
- CA2436832C CA2436832C CA2436832A CA2436832A CA2436832C CA 2436832 C CA2436832 C CA 2436832C CA 2436832 A CA2436832 A CA 2436832A CA 2436832 A CA2436832 A CA 2436832A CA 2436832 C CA2436832 C CA 2436832C
- Authority
- CA
- Canada
- Prior art keywords
- spp
- crystal form
- depsipeptide
- medicament
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/15—Depsipeptides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10104362.7 | 2001-02-01 | ||
| DE10104362A DE10104362A1 (de) | 2001-02-01 | 2001-02-01 | Kristallmodifikation eines cyclischen Depsipeptids mit besserer Wirksamkeit |
| PCT/EP2002/000541 WO2002066048A1 (de) | 2001-02-01 | 2002-01-21 | Kristallmodifikation eines cyclischen depsipeptids mit besserer wirksamkeit |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2436832A1 CA2436832A1 (en) | 2002-08-29 |
| CA2436832C true CA2436832C (en) | 2013-06-11 |
Family
ID=7672376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2436832A Expired - Lifetime CA2436832C (en) | 2001-02-01 | 2002-01-21 | Crystal form of a cyclic depsipeptide having improved activity |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US20040115483A1 (enExample) |
| EP (1) | EP1357932B1 (enExample) |
| JP (1) | JP2004525111A (enExample) |
| KR (2) | KR20030081378A (enExample) |
| CN (1) | CN1278735C (enExample) |
| AT (1) | ATE284703T1 (enExample) |
| AU (1) | AU2002226415B2 (enExample) |
| BR (1) | BRPI0206841B8 (enExample) |
| CA (1) | CA2436832C (enExample) |
| CR (1) | CR7039A (enExample) |
| CZ (1) | CZ299564B6 (enExample) |
| DE (2) | DE10104362A1 (enExample) |
| EE (1) | EE05490B1 (enExample) |
| ES (1) | ES2233805T3 (enExample) |
| HR (1) | HRP20030635A2 (enExample) |
| HU (1) | HU229229B1 (enExample) |
| IL (2) | IL157026A0 (enExample) |
| MX (1) | MXPA03006866A (enExample) |
| NO (1) | NO331289B1 (enExample) |
| NZ (1) | NZ527230A (enExample) |
| PL (1) | PL213106B1 (enExample) |
| PT (1) | PT1357932E (enExample) |
| RU (1) | RU2300390C2 (enExample) |
| SK (1) | SK286280B6 (enExample) |
| UA (1) | UA74623C2 (enExample) |
| WO (1) | WO2002066048A1 (enExample) |
| ZA (1) | ZA200305864B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080003546A1 (en) * | 2006-06-29 | 2008-01-03 | Dunbar Kimberly L | Animated digital charted yarncraft instruction |
| RS62130B1 (sr) | 2015-05-20 | 2021-08-31 | Boehringer Ingelheim Animal Health Usa Inc | Antihelmintička depsipeptidna jedinjenja |
| EP3397638B1 (en) | 2015-12-28 | 2023-08-23 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
| BR112019009977A2 (pt) | 2016-11-16 | 2019-08-27 | Boehringer Ingelheim Animal Health Usa Inc | compostos depsipeptídicos anti-helmínticos |
| CN114262303A (zh) * | 2022-01-04 | 2022-04-01 | 丽珠集团福州福兴医药有限公司 | 一种艾默德斯的单晶型ii及其制备方法 |
| CN114195732A (zh) * | 2022-01-04 | 2022-03-18 | 丽珠集团福州福兴医药有限公司 | 一种艾默德斯的单晶型iii及其制备方法 |
| CN115010680A (zh) * | 2022-07-13 | 2022-09-06 | 丽珠集团福州福兴医药有限公司 | 单晶型i的艾默德斯及其制备方法 |
| CN114989110A (zh) * | 2022-07-13 | 2022-09-02 | 丽珠集团福州福兴医药有限公司 | 单晶型ⅳ的艾默德斯及其制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2096907A (en) * | 1981-04-22 | 1982-10-27 | Exxon Research Engineering Co | Distillation column with steam stripping |
| DK0634408T3 (da) * | 1992-03-17 | 2002-04-22 | Fujisawa Pharmaceutical Co | Depsipeptidderivater, fremstilling og anvendelse deraf |
| DE4317458A1 (de) * | 1992-06-11 | 1993-12-16 | Bayer Ag | Verwendung von cyclischen Depsipeptiden mit 18 Ringatomen zur Bekämpfung von Endoparasiten, neue cyclische Depsipeptide mit 18 Ringatomen und Verfahren zu ihrer Herstellung |
| DE4400464A1 (de) * | 1994-01-11 | 1995-07-13 | Bayer Ag | Endoparasitizide Mittel |
| EP0872481B1 (en) * | 1995-06-30 | 2009-03-18 | Astellas Pharma Inc. | Depsipeptide derivative, process for production thereof, and novel intermediate therefor |
| DE69634961T2 (de) * | 1995-09-22 | 2006-04-20 | Bayer Ag | Neue zyklische depsipeptid pf1022 derivate |
| KR100551651B1 (ko) * | 1997-11-10 | 2006-02-13 | 아스텔라스세이야쿠 가부시키가이샤 | 뎁시펩티드 유도체의 신규 결정 및 그의 제조 방법 |
| DE10008128A1 (de) * | 2000-02-22 | 2001-08-23 | Bayer Ag | Endoparasitizide Mittel |
| DE10031044A1 (de) * | 2000-06-26 | 2002-01-03 | Bayer Ag | Endoparasitizide Mittel zur freiwilligen oralen Aufnahme durch Tiere |
-
2001
- 2001-02-01 DE DE10104362A patent/DE10104362A1/de not_active Withdrawn
-
2002
- 2002-01-21 AT AT02716073T patent/ATE284703T1/de active
- 2002-01-21 CA CA2436832A patent/CA2436832C/en not_active Expired - Lifetime
- 2002-01-21 BR BRPI0206841-9 patent/BRPI0206841B8/pt not_active IP Right Cessation
- 2002-01-21 HR HR20030635A patent/HRP20030635A2/hr not_active Application Discontinuation
- 2002-01-21 HU HU0302880A patent/HU229229B1/hu unknown
- 2002-01-21 EE EEP200300365A patent/EE05490B1/xx unknown
- 2002-01-21 IL IL15702602A patent/IL157026A0/xx unknown
- 2002-01-21 PT PT02716073T patent/PT1357932E/pt unknown
- 2002-01-21 CZ CZ20032063A patent/CZ299564B6/cs not_active IP Right Cessation
- 2002-01-21 PL PL362389A patent/PL213106B1/pl unknown
- 2002-01-21 JP JP2002565606A patent/JP2004525111A/ja active Pending
- 2002-01-21 KR KR10-2003-7009110A patent/KR20030081378A/ko not_active Ceased
- 2002-01-21 UA UA2003088108A patent/UA74623C2/uk unknown
- 2002-01-21 EP EP02716073A patent/EP1357932B1/de not_active Expired - Lifetime
- 2002-01-21 ES ES02716073T patent/ES2233805T3/es not_active Expired - Lifetime
- 2002-01-21 KR KR1020097006790A patent/KR20090041451A/ko not_active Ceased
- 2002-01-21 DE DE50201777T patent/DE50201777D1/de not_active Expired - Lifetime
- 2002-01-21 AU AU2002226415A patent/AU2002226415B2/en not_active Expired
- 2002-01-21 SK SK988-2003A patent/SK286280B6/sk not_active IP Right Cessation
- 2002-01-21 RU RU2003126589/15A patent/RU2300390C2/ru active
- 2002-01-21 CN CNB028044843A patent/CN1278735C/zh not_active Expired - Lifetime
- 2002-01-21 MX MXPA03006866A patent/MXPA03006866A/es active IP Right Grant
- 2002-01-21 NZ NZ527230A patent/NZ527230A/xx not_active IP Right Cessation
- 2002-01-21 WO PCT/EP2002/000541 patent/WO2002066048A1/de not_active Ceased
- 2002-01-21 US US10/470,853 patent/US20040115483A1/en not_active Abandoned
-
2003
- 2003-07-21 IL IL157026A patent/IL157026A/en unknown
- 2003-07-30 ZA ZA200305864A patent/ZA200305864B/en unknown
- 2003-07-30 CR CR7039A patent/CR7039A/es unknown
- 2003-07-30 NO NO20033413A patent/NO331289B1/no not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2222680C (en) | Endoparasiticidal agents | |
| HU218569B (hu) | Eljárás ciklusos depszipeptidek szulfonilezésére, az így előállított új vegyületek és parazitaellenes szerkénti alkalmazásuk | |
| US5036069A (en) | Anthelmintic active compound combinations | |
| HU226207B1 (en) | Endoparaziticide compositions | |
| KR100372348B1 (ko) | 내부기생충구제를위한곤충의니코틴효능성아세틸콜린수용체에대한길항물질및효능물질 | |
| AU2002226415B2 (en) | Crystal modification of a cyclic depsipeptide having improved strength | |
| MXPA96006179A (en) | Agonists and antagonists of the receptors of the nicotinic acid acetilcoline of insects for the control of endoparasi | |
| RU2250779C2 (ru) | Эндопаразитицидное средство | |
| HUP0102476A2 (hu) | Szubsztituált ciklooktadepszipeptidek | |
| WO2003082836A1 (en) | New dioxomorpholines for combating endoparasites | |
| MXPA00011972A (en) | Substituted cyclooctadepsipeptides |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20220121 |