EE05490B1 - Parendatud toimega tsklilise depsipeptiidi kristallivorm - Google Patents
Parendatud toimega tsklilise depsipeptiidi kristallivormInfo
- Publication number
- EE05490B1 EE05490B1 EEP200300365A EEP200300365A EE05490B1 EE 05490 B1 EE05490 B1 EE 05490B1 EE P200300365 A EEP200300365 A EE P200300365A EE P200300365 A EEP200300365 A EE P200300365A EE 05490 B1 EE05490 B1 EE 05490B1
- Authority
- EE
- Estonia
- Prior art keywords
- depsipeptide
- crystalline form
- improved activity
- formula
- activity
- Prior art date
Links
- 108010002156 Depsipeptides Proteins 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 244000079386 endoparasite Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/15—Depsipeptides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10104362A DE10104362A1 (de) | 2001-02-01 | 2001-02-01 | Kristallmodifikation eines cyclischen Depsipeptids mit besserer Wirksamkeit |
| PCT/EP2002/000541 WO2002066048A1 (de) | 2001-02-01 | 2002-01-21 | Kristallmodifikation eines cyclischen depsipeptids mit besserer wirksamkeit |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE200300365A EE200300365A (et) | 2003-10-15 |
| EE05490B1 true EE05490B1 (et) | 2011-12-15 |
Family
ID=7672376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200300365A EE05490B1 (et) | 2001-02-01 | 2002-01-21 | Parendatud toimega tsklilise depsipeptiidi kristallivorm |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US20040115483A1 (et) |
| EP (1) | EP1357932B1 (et) |
| JP (1) | JP2004525111A (et) |
| KR (2) | KR20090041451A (et) |
| CN (1) | CN1278735C (et) |
| AT (1) | ATE284703T1 (et) |
| AU (1) | AU2002226415B2 (et) |
| BR (1) | BRPI0206841B8 (et) |
| CA (1) | CA2436832C (et) |
| CR (1) | CR7039A (et) |
| CZ (1) | CZ299564B6 (et) |
| DE (2) | DE10104362A1 (et) |
| EE (1) | EE05490B1 (et) |
| ES (1) | ES2233805T3 (et) |
| HK (1) | HK1075013A1 (et) |
| HR (1) | HRP20030635A2 (et) |
| HU (1) | HU229229B1 (et) |
| IL (2) | IL157026A0 (et) |
| MX (1) | MXPA03006866A (et) |
| NO (1) | NO331289B1 (et) |
| NZ (1) | NZ527230A (et) |
| PL (1) | PL213106B1 (et) |
| PT (1) | PT1357932E (et) |
| RU (1) | RU2300390C2 (et) |
| SK (1) | SK286280B6 (et) |
| UA (1) | UA74623C2 (et) |
| WO (1) | WO2002066048A1 (et) |
| ZA (1) | ZA200305864B (et) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080003546A1 (en) * | 2006-06-29 | 2008-01-03 | Dunbar Kimberly L | Animated digital charted yarncraft instruction |
| SI3298027T1 (sl) | 2015-05-20 | 2021-08-31 | Boehringer Ingelheim Animal Health USA Inc. | Antihelmintične depsipeptidne spojine |
| WO2017116702A1 (en) | 2015-12-28 | 2017-07-06 | Merial, Inc. | Anthelmintic depsipeptide compounds |
| CN110167921A (zh) | 2016-11-16 | 2019-08-23 | 勃林格殷格翰动物保健美国公司 | 驱蠕虫缩肽化合物 |
| CN114195732A (zh) * | 2022-01-04 | 2022-03-18 | 丽珠集团福州福兴医药有限公司 | 一种艾默德斯的单晶型iii及其制备方法 |
| CN114262303A (zh) * | 2022-01-04 | 2022-04-01 | 丽珠集团福州福兴医药有限公司 | 一种艾默德斯的单晶型ii及其制备方法 |
| CN114989110A (zh) * | 2022-07-13 | 2022-09-02 | 丽珠集团福州福兴医药有限公司 | 单晶型ⅳ的艾默德斯及其制备方法 |
| CN115010680A (zh) * | 2022-07-13 | 2022-09-06 | 丽珠集团福州福兴医药有限公司 | 单晶型i的艾默德斯及其制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2096907A (en) * | 1981-04-22 | 1982-10-27 | Exxon Research Engineering Co | Distillation column with steam stripping |
| CA2132199C (en) * | 1992-03-17 | 2000-01-18 | Hitoshi Nishiyama | Depsipeptide derivative, production thereof and use thereof |
| DE4317458A1 (de) * | 1992-06-11 | 1993-12-16 | Bayer Ag | Verwendung von cyclischen Depsipeptiden mit 18 Ringatomen zur Bekämpfung von Endoparasiten, neue cyclische Depsipeptide mit 18 Ringatomen und Verfahren zu ihrer Herstellung |
| DE4400464A1 (de) * | 1994-01-11 | 1995-07-13 | Bayer Ag | Endoparasitizide Mittel |
| JP3985050B2 (ja) * | 1995-06-30 | 2007-10-03 | アステラス製薬株式会社 | デプシペプチド誘導体その製造法およびその新規中間体 |
| CZ295705B6 (cs) * | 1995-09-22 | 2005-10-12 | Bayer Aktiengesellschaft | Cyklodepsipeptidové deriváty sloučeniny PF1022 a farmaceutický prostředek s jejich obsahem |
| NZ504812A (en) * | 1997-11-10 | 2002-08-28 | Fujisawa Pharmaceutical Co | A crystal of a phenyl-morpholino substituted depsipeptide derivative |
| DE10008128A1 (de) * | 2000-02-22 | 2001-08-23 | Bayer Ag | Endoparasitizide Mittel |
| DE10031044A1 (de) * | 2000-06-26 | 2002-01-03 | Bayer Ag | Endoparasitizide Mittel zur freiwilligen oralen Aufnahme durch Tiere |
-
2001
- 2001-02-01 DE DE10104362A patent/DE10104362A1/de not_active Withdrawn
-
2002
- 2002-01-21 CA CA2436832A patent/CA2436832C/en not_active Expired - Lifetime
- 2002-01-21 KR KR1020097006790A patent/KR20090041451A/ko not_active Application Discontinuation
- 2002-01-21 AT AT02716073T patent/ATE284703T1/de active
- 2002-01-21 SK SK988-2003A patent/SK286280B6/sk not_active IP Right Cessation
- 2002-01-21 US US10/470,853 patent/US20040115483A1/en not_active Abandoned
- 2002-01-21 IL IL15702602A patent/IL157026A0/xx unknown
- 2002-01-21 BR BRPI0206841-9 patent/BRPI0206841B8/pt not_active IP Right Cessation
- 2002-01-21 RU RU2003126589/15A patent/RU2300390C2/ru active
- 2002-01-21 CN CNB028044843A patent/CN1278735C/zh not_active Expired - Lifetime
- 2002-01-21 JP JP2002565606A patent/JP2004525111A/ja active Pending
- 2002-01-21 EE EEP200300365A patent/EE05490B1/et unknown
- 2002-01-21 HU HU0302880A patent/HU229229B1/hu unknown
- 2002-01-21 PL PL362389A patent/PL213106B1/pl unknown
- 2002-01-21 DE DE50201777T patent/DE50201777D1/de not_active Expired - Lifetime
- 2002-01-21 PT PT02716073T patent/PT1357932E/pt unknown
- 2002-01-21 WO PCT/EP2002/000541 patent/WO2002066048A1/de active IP Right Grant
- 2002-01-21 EP EP02716073A patent/EP1357932B1/de not_active Expired - Lifetime
- 2002-01-21 UA UA2003088108A patent/UA74623C2/uk unknown
- 2002-01-21 AU AU2002226415A patent/AU2002226415B2/en not_active Expired
- 2002-01-21 ES ES02716073T patent/ES2233805T3/es not_active Expired - Lifetime
- 2002-01-21 KR KR10-2003-7009110A patent/KR20030081378A/ko not_active Application Discontinuation
- 2002-01-21 NZ NZ527230A patent/NZ527230A/xx not_active IP Right Cessation
- 2002-01-21 MX MXPA03006866A patent/MXPA03006866A/es active IP Right Grant
- 2002-01-21 CZ CZ20032063A patent/CZ299564B6/cs not_active IP Right Cessation
-
2003
- 2003-07-21 IL IL157026A patent/IL157026A/en unknown
- 2003-07-30 NO NO20033413A patent/NO331289B1/no not_active IP Right Cessation
- 2003-07-30 ZA ZA200305864A patent/ZA200305864B/en unknown
- 2003-07-30 CR CR7039A patent/CR7039A/es unknown
- 2003-08-11 HR HR20030635A patent/HRP20030635A2/hr not_active Application Discontinuation
-
2005
- 2005-08-24 HK HK05107422A patent/HK1075013A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB1A | Change in the ownership or in the address of the owner | ||
| GB1A | Change in the ownership or in the address of the owner |