CA2336139C - Large porous particles emitted from an inhaler - Google Patents
Large porous particles emitted from an inhaler Download PDFInfo
- Publication number
- CA2336139C CA2336139C CA002336139A CA2336139A CA2336139C CA 2336139 C CA2336139 C CA 2336139C CA 002336139 A CA002336139 A CA 002336139A CA 2336139 A CA2336139 A CA 2336139A CA 2336139 C CA2336139 C CA 2336139C
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- Prior art keywords
- particles
- dppc
- agent
- surfactant
- therapeutic
- Prior art date
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- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 description 1
- 229960001860 salicylate Drugs 0.000 description 1
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- 150000003384 small molecules Chemical class 0.000 description 1
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- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 description 1
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- NJGWOFRZMQRKHT-WGVNQGGSSA-N surfactin C Chemical compound CC(C)CCCCCCCCC[C@@H]1CC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O1 NJGWOFRZMQRKHT-WGVNQGGSSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Otolaryngology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9045498P | 1998-06-24 | 1998-06-24 | |
| US60/090,454 | 1998-06-24 | ||
| PCT/US1999/014074 WO1999066903A2 (en) | 1998-06-24 | 1999-06-22 | Large porous particles emitted from an inhaler |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2336139A1 CA2336139A1 (en) | 1999-12-29 |
| CA2336139C true CA2336139C (en) | 2008-10-14 |
Family
ID=22222836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002336139A Expired - Fee Related CA2336139C (en) | 1998-06-24 | 1999-06-22 | Large porous particles emitted from an inhaler |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1089712B1 (https=) |
| JP (1) | JP2002518432A (https=) |
| AT (1) | ATE238768T1 (https=) |
| AU (1) | AU747231B2 (https=) |
| CA (1) | CA2336139C (https=) |
| DE (1) | DE69907456T2 (https=) |
| ES (1) | ES2198922T3 (https=) |
| WO (1) | WO1999066903A2 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5174988A (en) * | 1989-07-27 | 1992-12-29 | Scientific Development & Research, Inc. | Phospholipid delivery system |
| PL319600A1 (en) * | 1994-09-29 | 1997-08-18 | Andaris Ltd | Spray-dried microparticles as therapeutic carriers |
| GB9606188D0 (en) * | 1996-03-23 | 1996-05-29 | Danbiosyst Uk | Pollysaccharide microspheres for the pulmonary delivery of drugs |
| US5874064A (en) * | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| DE69732306T2 (de) * | 1997-01-16 | 2006-01-12 | Massachusetts Institute Of Technology, Cambridge | Zubereitung von partikelhaltigen arzneimitteln zur inhalation |
-
1999
- 1999-06-22 CA CA002336139A patent/CA2336139C/en not_active Expired - Fee Related
- 1999-06-22 EP EP99930552A patent/EP1089712B1/en not_active Expired - Lifetime
- 1999-06-22 AT AT99930552T patent/ATE238768T1/de not_active IP Right Cessation
- 1999-06-22 DE DE69907456T patent/DE69907456T2/de not_active Expired - Fee Related
- 1999-06-22 AU AU47068/99A patent/AU747231B2/en not_active Ceased
- 1999-06-22 WO PCT/US1999/014074 patent/WO1999066903A2/en not_active Ceased
- 1999-06-22 JP JP2000555589A patent/JP2002518432A/ja active Pending
- 1999-06-22 ES ES99930552T patent/ES2198922T3/es not_active Expired - Lifetime
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|---|---|
| JP2002518432A (ja) | 2002-06-25 |
| EP1089712B1 (en) | 2003-05-02 |
| AU747231B2 (en) | 2002-05-09 |
| AU4706899A (en) | 2000-01-10 |
| DE69907456T2 (de) | 2004-03-25 |
| ES2198922T3 (es) | 2004-02-01 |
| WO1999066903A3 (en) | 2000-02-03 |
| CA2336139A1 (en) | 1999-12-29 |
| ATE238768T1 (de) | 2003-05-15 |
| WO1999066903A2 (en) | 1999-12-29 |
| DE69907456D1 (de) | 2003-06-05 |
| EP1089712A2 (en) | 2001-04-11 |
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