CA2212057C - Photochemically cross-linked polysaccharide derivatives as supports for the chromatographic separation of enantiomers - Google Patents

Photochemically cross-linked polysaccharide derivatives as supports for the chromatographic separation of enantiomers Download PDF

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Publication number
CA2212057C
CA2212057C CA002212057A CA2212057A CA2212057C CA 2212057 C CA2212057 C CA 2212057C CA 002212057 A CA002212057 A CA 002212057A CA 2212057 A CA2212057 A CA 2212057A CA 2212057 C CA2212057 C CA 2212057C
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CA
Canada
Prior art keywords
cellulose
compound
groups
formula
unsubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002212057A
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English (en)
French (fr)
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CA2212057A1 (en
Inventor
Eric Francotte
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
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Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of CA2212057A1 publication Critical patent/CA2212057A1/en
Application granted granted Critical
Publication of CA2212057C publication Critical patent/CA2212057C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/29—Chiral phases
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B01J20/3282—Crosslinked polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C08B15/005—Crosslinking of cellulose derivatives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C08B15/05—Derivatives containing elements other than carbon, hydrogen, oxygen, halogens or sulfur
    • C08B15/06—Derivatives containing elements other than carbon, hydrogen, oxygen, halogens or sulfur containing nitrogen, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B33/00—Preparation of derivatives of amylose
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
CA002212057A 1995-03-07 1996-02-24 Photochemically cross-linked polysaccharide derivatives as supports for the chromatographic separation of enantiomers Expired - Lifetime CA2212057C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH640/95 1995-03-07
CH64095 1995-03-07
PCT/EP1996/000773 WO1996027615A1 (en) 1995-03-07 1996-02-24 Photochemically cross-linked polysaccharide derivatives as supports for the chromatographic separation of enantiomers

Publications (2)

Publication Number Publication Date
CA2212057A1 CA2212057A1 (en) 1996-09-12
CA2212057C true CA2212057C (en) 2007-02-13

Family

ID=4191727

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002212057A Expired - Lifetime CA2212057C (en) 1995-03-07 1996-02-24 Photochemically cross-linked polysaccharide derivatives as supports for the chromatographic separation of enantiomers

Country Status (18)

Country Link
US (1) US6011149A (ko)
EP (1) EP0813546B1 (ko)
JP (2) JP4201832B2 (ko)
KR (1) KR19980702832A (ko)
CN (1) CN1177358A (ko)
AT (1) ATE220691T1 (ko)
AU (1) AU708454B2 (ko)
CA (1) CA2212057C (ko)
CY (1) CY2419B1 (ko)
CZ (1) CZ278797A3 (ko)
DE (1) DE69622381T2 (ko)
DK (1) DK0813546T3 (ko)
ES (1) ES2179935T3 (ko)
FI (1) FI116840B (ko)
HU (1) HUP9802744A3 (ko)
NO (1) NO974092D0 (ko)
PT (1) PT813546E (ko)
WO (1) WO1996027615A1 (ko)

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Publication number Priority date Publication date Assignee Title
US20080132695A1 (en) * 1995-07-21 2008-06-05 Eric Francotte Cross-linked Polysaccharide Derivatives
US6107492A (en) * 1998-05-08 2000-08-22 Ucb, S.A. Process for the preparation of levetiracetam
NL1015313C2 (nl) 2000-05-26 2001-11-27 Dsm Nv Werkwijze voor de bereiding van enantiomeer verrijkte esters en alcoholen.
WO2002103349A1 (fr) * 2001-06-15 2002-12-27 Daicel Chemical Industries, Ltd. Agent de separation pour isomere optique
FR2829947B1 (fr) * 2001-09-21 2004-10-15 Chiralsep Sarl Reseau polymere tridimensionnel reticule, son procede de preparation, materiau support comportant ce reseau et leurs utilisations
FR2834227A1 (fr) * 2001-12-27 2003-07-04 Chiralsep Sarl Materiaux supports optiquement actifs, leur procede de preparation et leurs utilisations
DE602004006975D1 (de) * 2003-03-27 2007-07-26 Chirosep Dreidimensionales vernetztes polymernetzwerk, verfahren zu dessen herstellung, dieses enthaltender trägermaterial und ihre verwendung
CN100387333C (zh) * 2003-12-05 2008-05-14 中国科学院大连化学物理研究所 一种自由基共聚法制备键合型多糖类手性固定相的方法
CN100386142C (zh) * 2003-12-05 2008-05-07 中国科学院大连化学物理研究所 一种合成键合型多糖类手性固定相的方法
CZ302504B6 (cs) 2009-12-11 2011-06-22 Contipro C A.S. Derivát kyseliny hyaluronové oxidovaný v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd, zpusob jeho prípravy a zpusob jeho modifikace
CZ302503B6 (cs) 2009-12-11 2011-06-22 Contipro C A.S. Zpusob prípravy derivátu kyseliny hyaluronové oxidovaného v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd a zpusob jeho modifikace
CN102423699B (zh) * 2011-09-02 2013-08-07 武汉工程大学 一种涂覆型多糖类手性固定相的制备方法
CZ2012136A3 (cs) 2012-02-28 2013-06-05 Contipro Biotech S.R.O. Deriváty na bázi kyseliny hyaluronové schopné tvorit hydrogely, zpusob jejich prípravy, hydrogely na bázi techto derivátu, zpusob jejich prípravy a pouzití
CZ304512B6 (cs) 2012-08-08 2014-06-11 Contipro Biotech S.R.O. Derivát kyseliny hyaluronové, způsob jeho přípravy, způsob jeho modifikace a použití
CZ304654B6 (cs) 2012-11-27 2014-08-20 Contipro Biotech S.R.O. Nanomicelární kompozice na bázi C6-C18-acylovaného hyaluronanu, způsob přípravy C6-C18-acylovaného hyaluronanu, způsob přípravy nanomicelární kompozice a stabilizované nanomicelární kompozice a použití
CZ2012844A3 (cs) 2012-11-27 2014-02-05 Contipro Biotech S.R.O. Fotoreaktivní derivát kyseliny hyaluronové, způsob jeho přípravy, 3D síťovaný derivát kyseliny hyaluronové, způsob jeho přípravy a použití
CZ305153B6 (cs) 2014-03-11 2015-05-20 Contipro Biotech S.R.O. Konjugáty oligomeru kyseliny hyaluronové nebo její soli, způsob jejich přípravy a použití
CZ2014451A3 (cs) 2014-06-30 2016-01-13 Contipro Pharma A.S. Protinádorová kompozice na bázi kyseliny hyaluronové a anorganických nanočástic, způsob její přípravy a použití
CZ309295B6 (cs) 2015-03-09 2022-08-10 Contipro A.S. Samonosný, biodegradabilní film na bázi hydrofobizované kyseliny hyaluronové, způsob jeho přípravy a použití
KR101956832B1 (ko) 2015-06-12 2019-03-12 주식회사 엘지화학 폴리카보네이트 수지 조성물 및 이로 이루어진 광학 성형품
CZ2015398A3 (cs) 2015-06-15 2017-02-08 Contipro A.S. Způsob síťování polysacharidů s využitím fotolabilních chránicích skupin
CZ306662B6 (cs) 2015-06-26 2017-04-26 Contipro A.S. Deriváty sulfatovaných polysacharidů, způsob jejich přípravy, způsob jejich modifikace a použití
WO2017142205A1 (ko) 2016-02-18 2017-08-24 주식회사 엘지화학 폴리카보네이트 수지 조성물 및 이를 이용한 광학 성형품
CZ308106B6 (cs) 2016-06-27 2020-01-08 Contipro A.S. Nenasycené deriváty polysacharidů, způsob jejich přípravy a jejich použití
KR102049577B1 (ko) 2016-10-31 2019-11-27 주식회사 엘지화학 폴리카보네이트 수지 조성물 및 이로 이루어진 광학 성형품
CN111909281B (zh) * 2020-08-31 2022-05-10 武汉工程大学 直链淀粉-2,3-二(芳香基氨基甲酸酯)-6-脱氧-6-芳香基脲的制备方法

Family Cites Families (8)

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Publication number Priority date Publication date Assignee Title
US3960685A (en) * 1973-11-12 1976-06-01 Sumitomo Chemical Company, Limited Photosensitive resin composition containing pullulan or esters thereof
DE2626795A1 (de) * 1975-06-18 1976-12-30 Ciba Geigy Ag Imidylverbindungen
US4079041A (en) * 1975-06-18 1978-03-14 Ciba-Geigy Corporation Crosslinkable polymeric compounds
CH599153A5 (ko) * 1975-06-18 1978-05-12 Ciba Geigy Ag
US4861872A (en) * 1986-03-20 1989-08-29 Daicel Chemical Industries, Ltd. Alkyl-phenylcarbamate derivative of polysaccharide
US4861629A (en) * 1987-12-23 1989-08-29 Hercules Incorporated Polyfunctional ethylenically unsaturated cellulosic polymer-based photocurable compositions
US5138006A (en) * 1991-02-11 1992-08-11 Eastman Kodak Company Radiation polymerizable starch ester-urethanes
JP2855307B2 (ja) * 1992-02-05 1999-02-10 生化学工業株式会社 光反応性グリコサミノグリカン、架橋グリコサミノグリカン及びそれらの製造方法

Also Published As

Publication number Publication date
CA2212057A1 (en) 1996-09-12
HUP9802744A2 (hu) 1999-03-29
DE69622381T2 (de) 2003-01-16
CN1177358A (zh) 1998-03-25
ES2179935T3 (es) 2003-02-01
AU4941496A (en) 1996-09-23
ATE220691T1 (de) 2002-08-15
EP0813546A1 (en) 1997-12-29
DE69622381D1 (de) 2002-08-22
JPH11509875A (ja) 1999-08-31
NO974092L (no) 1997-09-05
MX9706802A (es) 1997-11-29
FI116840B (fi) 2006-03-15
NO974092D0 (no) 1997-09-05
JP4836897B2 (ja) 2011-12-14
JP4201832B2 (ja) 2008-12-24
WO1996027615A1 (en) 1996-09-12
AU708454B2 (en) 1999-08-05
US6011149A (en) 2000-01-04
PT813546E (pt) 2002-11-29
CZ278797A3 (en) 1997-11-12
DK0813546T3 (da) 2002-11-04
FI973149A (fi) 1997-09-04
EP0813546B1 (en) 2002-07-17
FI973149A0 (fi) 1997-07-29
JP2008045131A (ja) 2008-02-28
HUP9802744A3 (en) 1999-04-28
KR19980702832A (ko) 1998-08-05
CY2419B1 (en) 2004-11-12

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