DE69622381T2 - Fotochemisch vernetzte polysaccharidderivate zur chromatographischen trennung von enantiomeren - Google Patents

Fotochemisch vernetzte polysaccharidderivate zur chromatographischen trennung von enantiomeren

Info

Publication number
DE69622381T2
DE69622381T2 DE69622381T DE69622381T DE69622381T2 DE 69622381 T2 DE69622381 T2 DE 69622381T2 DE 69622381 T DE69622381 T DE 69622381T DE 69622381 T DE69622381 T DE 69622381T DE 69622381 T2 DE69622381 T2 DE 69622381T2
Authority
DE
Germany
Prior art keywords
pct
enantiomers
chromatographic separation
date sep
polysaccharide derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69622381T
Other languages
English (en)
Other versions
DE69622381D1 (de
Inventor
Eric Francotte
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE69622381D1 publication Critical patent/DE69622381D1/de
Application granted granted Critical
Publication of DE69622381T2 publication Critical patent/DE69622381T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00Separation of optically-active compounds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/29Chiral phases
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204Inorganic carriers, supports or substrates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268Macromolecular compounds
    • B01J20/3272Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268Macromolecular compounds
    • B01J20/328Polymers on the carrier being further modified
    • B01J20/3282Crosslinked polymers
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C08B15/005Crosslinking of cellulose derivatives
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C08B15/05Derivatives containing elements other than carbon, hydrogen, oxygen, halogens or sulfur
    • C08B15/06Derivatives containing elements other than carbon, hydrogen, oxygen, halogens or sulfur containing nitrogen, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B33/00Preparation of derivatives of amylose
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54Sorbents specially adapted for analytical or investigative chromatography
DE69622381T 1995-03-07 1996-02-24 Fotochemisch vernetzte polysaccharidderivate zur chromatographischen trennung von enantiomeren Expired - Lifetime DE69622381T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH64095 1995-03-07
PCT/EP1996/000773 WO1996027615A1 (en) 1995-03-07 1996-02-24 Photochemically cross-linked polysaccharide derivatives as supports for the chromatographic separation of enantiomers

Publications (2)

Publication Number Publication Date
DE69622381D1 DE69622381D1 (de) 2002-08-22
DE69622381T2 true DE69622381T2 (de) 2003-01-16

Family

ID=4191727

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69622381T Expired - Lifetime DE69622381T2 (de) 1995-03-07 1996-02-24 Fotochemisch vernetzte polysaccharidderivate zur chromatographischen trennung von enantiomeren

Country Status (18)

Country Link
US (1) US6011149A (de)
EP (1) EP0813546B1 (de)
JP (2) JP4201832B2 (de)
KR (1) KR19980702832A (de)
CN (1) CN1177358A (de)
AT (1) ATE220691T1 (de)
AU (1) AU708454B2 (de)
CA (1) CA2212057C (de)
CY (1) CY2419B1 (de)
CZ (1) CZ278797A3 (de)
DE (1) DE69622381T2 (de)
DK (1) DK0813546T3 (de)
ES (1) ES2179935T3 (de)
FI (1) FI116840B (de)
HU (1) HUP9802744A3 (de)
NO (1) NO974092D0 (de)
PT (1) PT813546E (de)
WO (1) WO1996027615A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080132695A1 (en) * 1995-07-21 2008-06-05 Eric Francotte Cross-linked Polysaccharide Derivatives
US6107492A (en) * 1998-05-08 2000-08-22 Ucb, S.A. Process for the preparation of levetiracetam
NL1015313C2 (nl) 2000-05-26 2001-11-27 Dsm Nv Werkwijze voor de bereiding van enantiomeer verrijkte esters en alcoholen.
WO2002103349A1 (fr) * 2001-06-15 2002-12-27 Daicel Chemical Industries, Ltd. Agent de separation pour isomere optique
FR2829947B1 (fr) * 2001-09-21 2004-10-15 Chiralsep Sarl Reseau polymere tridimensionnel reticule, son procede de preparation, materiau support comportant ce reseau et leurs utilisations
FR2834227A1 (fr) 2001-12-27 2003-07-04 Chiralsep Sarl Materiaux supports optiquement actifs, leur procede de preparation et leurs utilisations
WO2004085485A1 (en) * 2003-03-27 2004-10-07 Chirosep Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof
CN100386142C (zh) * 2003-12-05 2008-05-07 中国科学院大连化学物理研究所 一种合成键合型多糖类手性固定相的方法
CN100387333C (zh) * 2003-12-05 2008-05-14 中国科学院大连化学物理研究所 一种自由基共聚法制备键合型多糖类手性固定相的方法
CZ302503B6 (cs) 2009-12-11 2011-06-22 Contipro C A.S. Zpusob prípravy derivátu kyseliny hyaluronové oxidovaného v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd a zpusob jeho modifikace
CZ302504B6 (cs) 2009-12-11 2011-06-22 Contipro C A.S. Derivát kyseliny hyaluronové oxidovaný v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd, zpusob jeho prípravy a zpusob jeho modifikace
CN102423699B (zh) * 2011-09-02 2013-08-07 武汉工程大学 一种涂覆型多糖类手性固定相的制备方法
CZ2012136A3 (cs) 2012-02-28 2013-06-05 Contipro Biotech S.R.O. Deriváty na bázi kyseliny hyaluronové schopné tvorit hydrogely, zpusob jejich prípravy, hydrogely na bázi techto derivátu, zpusob jejich prípravy a pouzití
CZ304512B6 (cs) 2012-08-08 2014-06-11 Contipro Biotech S.R.O. Derivát kyseliny hyaluronové, způsob jeho přípravy, způsob jeho modifikace a použití
CZ2012844A3 (cs) 2012-11-27 2014-02-05 Contipro Biotech S.R.O. Fotoreaktivní derivát kyseliny hyaluronové, způsob jeho přípravy, 3D síťovaný derivát kyseliny hyaluronové, způsob jeho přípravy a použití
CZ304654B6 (cs) 2012-11-27 2014-08-20 Contipro Biotech S.R.O. Nanomicelární kompozice na bázi C6-C18-acylovaného hyaluronanu, způsob přípravy C6-C18-acylovaného hyaluronanu, způsob přípravy nanomicelární kompozice a stabilizované nanomicelární kompozice a použití
CZ2014150A3 (cs) 2014-03-11 2015-05-20 Contipro Biotech S.R.O. Konjugáty oligomeru kyseliny hyaluronové nebo její soli, způsob jejich přípravy a použití
CZ2014451A3 (cs) 2014-06-30 2016-01-13 Contipro Pharma A.S. Protinádorová kompozice na bázi kyseliny hyaluronové a anorganických nanočástic, způsob její přípravy a použití
CZ309295B6 (cs) 2015-03-09 2022-08-10 Contipro A.S. Samonosný, biodegradabilní film na bázi hydrofobizované kyseliny hyaluronové, způsob jeho přípravy a použití
KR101956832B1 (ko) 2015-06-12 2019-03-12 주식회사 엘지화학 폴리카보네이트 수지 조성물 및 이로 이루어진 광학 성형품
CZ2015398A3 (cs) 2015-06-15 2017-02-08 Contipro A.S. Způsob síťování polysacharidů s využitím fotolabilních chránicích skupin
CZ306662B6 (cs) 2015-06-26 2017-04-26 Contipro A.S. Deriváty sulfatovaných polysacharidů, způsob jejich přípravy, způsob jejich modifikace a použití
CN107429055B (zh) 2016-02-18 2019-08-23 株式会社Lg化学 聚碳酸酯树脂组合物以及使用该组合物的光学模制品
CZ308106B6 (cs) 2016-06-27 2020-01-08 Contipro A.S. Nenasycené deriváty polysacharidů, způsob jejich přípravy a jejich použití
KR102049577B1 (ko) 2016-10-31 2019-11-27 주식회사 엘지화학 폴리카보네이트 수지 조성물 및 이로 이루어진 광학 성형품
CN111909281B (zh) * 2020-08-31 2022-05-10 武汉工程大学 直链淀粉-2,3-二(芳香基氨基甲酸酯)-6-脱氧-6-芳香基脲的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3960685A (en) * 1973-11-12 1976-06-01 Sumitomo Chemical Company, Limited Photosensitive resin composition containing pullulan or esters thereof
CH599153A5 (de) * 1975-06-18 1978-05-12 Ciba Geigy Ag
US4107174A (en) * 1975-06-18 1978-08-15 Ciba-Geigy Corporation Imidyl compounds
US4079041A (en) * 1975-06-18 1978-03-14 Ciba-Geigy Corporation Crosslinkable polymeric compounds
US4861872A (en) * 1986-03-20 1989-08-29 Daicel Chemical Industries, Ltd. Alkyl-phenylcarbamate derivative of polysaccharide
US4861629A (en) * 1987-12-23 1989-08-29 Hercules Incorporated Polyfunctional ethylenically unsaturated cellulosic polymer-based photocurable compositions
US5138006A (en) * 1991-02-11 1992-08-11 Eastman Kodak Company Radiation polymerizable starch ester-urethanes
JP2855307B2 (ja) * 1992-02-05 1999-02-10 生化学工業株式会社 光反応性グリコサミノグリカン、架橋グリコサミノグリカン及びそれらの製造方法

Also Published As

Publication number Publication date
AU708454B2 (en) 1999-08-05
EP0813546A1 (de) 1997-12-29
ATE220691T1 (de) 2002-08-15
FI116840B (fi) 2006-03-15
HUP9802744A2 (hu) 1999-03-29
DK0813546T3 (da) 2002-11-04
JPH11509875A (ja) 1999-08-31
WO1996027615A1 (en) 1996-09-12
KR19980702832A (ko) 1998-08-05
EP0813546B1 (de) 2002-07-17
FI973149A (fi) 1997-09-04
CA2212057A1 (en) 1996-09-12
ES2179935T3 (es) 2003-02-01
AU4941496A (en) 1996-09-23
CA2212057C (en) 2007-02-13
NO974092L (no) 1997-09-05
JP4836897B2 (ja) 2011-12-14
DE69622381D1 (de) 2002-08-22
CY2419B1 (en) 2004-11-12
NO974092D0 (no) 1997-09-05
FI973149A0 (fi) 1997-07-29
CN1177358A (zh) 1998-03-25
CZ278797A3 (en) 1997-11-12
MX9706802A (es) 1997-11-29
JP4201832B2 (ja) 2008-12-24
HUP9802744A3 (en) 1999-04-28
PT813546E (pt) 2002-11-29
US6011149A (en) 2000-01-04
JP2008045131A (ja) 2008-02-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN