CA1273629A - 7-amino-3-propenylcephalosporanic acid and esters thereof - Google Patents

7-amino-3-propenylcephalosporanic acid and esters thereof

Info

Publication number
CA1273629A
CA1273629A CA000507037A CA507037A CA1273629A CA 1273629 A CA1273629 A CA 1273629A CA 000507037 A CA000507037 A CA 000507037A CA 507037 A CA507037 A CA 507037A CA 1273629 A CA1273629 A CA 1273629A
Authority
CA
Canada
Prior art keywords
compound
amino
group
propen
cephem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000507037A
Other languages
English (en)
French (fr)
Inventor
Jun Okumura
Hideaki Hoshi
Shimpei Aburaki
Takayuki Naito
Yoshio Abe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Application granted granted Critical
Publication of CA1273629A publication Critical patent/CA1273629A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
CA000507037A 1985-04-22 1986-04-18 7-amino-3-propenylcephalosporanic acid and esters thereof Expired - Lifetime CA1273629A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72587185A 1985-04-22 1985-04-22
US725,871 1985-04-22

Publications (1)

Publication Number Publication Date
CA1273629A true CA1273629A (en) 1990-09-04

Family

ID=24916301

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000507037A Expired - Lifetime CA1273629A (en) 1985-04-22 1986-04-18 7-amino-3-propenylcephalosporanic acid and esters thereof

Country Status (38)

Country Link
JP (1) JPS61249989A (sv)
KR (1) KR860008189A (sv)
CN (1) CN1015714B (sv)
AR (1) AR242581A1 (sv)
AT (1) AT392072B (sv)
AU (1) AU589170B2 (sv)
BE (1) BE904646A (sv)
CA (1) CA1273629A (sv)
CH (1) CH671399A5 (sv)
CS (1) CS270435B2 (sv)
CY (1) CY1571A (sv)
DD (1) DD244557A5 (sv)
DE (1) DE3613365A1 (sv)
DK (1) DK163584C (sv)
EG (1) EG18001A (sv)
ES (1) ES8800236A1 (sv)
FI (1) FI84268C (sv)
FR (1) FR2580652B1 (sv)
GB (1) GB2173798B (sv)
GR (1) GR861065B (sv)
HK (1) HK106290A (sv)
HU (1) HU195223B (sv)
IE (1) IE59014B1 (sv)
IT (1) IT1228241B (sv)
LU (1) LU86402A1 (sv)
MY (1) MY100694A (sv)
NL (1) NL192205C (sv)
NO (1) NO164659C (sv)
NZ (1) NZ215717A (sv)
OA (1) OA08245A (sv)
PT (1) PT82436B (sv)
SE (1) SE500217C2 (sv)
SG (1) SG90890G (sv)
SU (1) SU1435155A3 (sv)
YU (1) YU43697B (sv)
ZA (1) ZA862985B (sv)
ZM (1) ZM4286A1 (sv)
ZW (1) ZW9086A1 (sv)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
US4870168A (en) * 1987-02-26 1989-09-26 Bristol-Myers Company 3-Unsaturated alkyl cephems from 3-triflyl cephems
DE3933934A1 (de) * 1989-10-03 1991-04-11 Bayer Ag Verfahren zur herstellung von 7-amino-3-((z)-1-propen-1-yl)-3-cephem-4-carbonsaeure
DE69231815T2 (de) * 1991-03-08 2001-09-27 Biochemie Gmbh Verfahren zur Herstellung von Cephalosporinen und Zwischenprodukte in diesem Verfahren
JP2825655B2 (ja) * 1992-02-05 1998-11-18 バイオケミ・ゲゼルシヤフト・エム・ベー・ハー ３−セフェム−４−カルボン酸誘導体の精製方法
AT399876B (de) * 1992-02-05 1995-08-25 Biochemie Gmbh Verfahren zur abreicherung von 7-amino-3-((e)-1- propen-1-yl)-3-cephem-4-carbonsäure
JPH07173168A (ja) * 1993-07-14 1995-07-11 Sumitomo Chem Co Ltd セフェム系化合物、その製法、およびそれのセフェム系抗生物質製造への利用
US20060173176A1 (en) * 2002-10-08 2006-08-03 Yatendra Kumar Process for the preparation of (z)-isomer enriched 7-amino-3-propen-1-yl-3-cephem-4-carboxylic acid
WO2005042543A1 (en) * 2003-10-30 2005-05-12 Cj Corporation Processes for the preparation of cephem derivatives
JP4046708B2 (ja) * 2004-06-04 2008-02-13 明治製菓株式会社 ３−アルケニルセフェム化合物の製造方法
EP1809638B1 (en) 2004-11-01 2010-02-17 Hetero Drugs Limited A novel process for preparation of cefprozil intermediate
CN103183686B (zh) * 2011-12-30 2016-06-29 浙江新和成股份有限公司 7β-氨基-7α-甲氧基-3-头孢烯化合物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3769277A (en) * 1970-01-23 1973-10-30 Glaxo Lab Ltd Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group
US4110534A (en) * 1970-01-23 1978-08-29 Glaxo Laboratories Limited Process for the preparation of 3-vinyl and substituted vinyl cephalosporins
GB1342241A (en) * 1970-01-23 1974-01-03 Glaxo Lab Ltd Cephalosporin compounds
US4065620A (en) * 1971-06-14 1977-12-27 Eli Lilly And Company 3-(Substituted) vinyl cephalosporins
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US4520022A (en) * 1983-01-28 1985-05-28 Bristol-Myers Company Substituted vinyl cephalosporins
AU566944B2 (en) * 1983-10-07 1987-11-05 Gist-Brocades N.V. Preparation of 3-cephem derivatives

Also Published As

Publication number Publication date
KR860008189A (ko) 1986-11-12
SE8601825D0 (sv) 1986-04-21
IE59014B1 (en) 1993-12-15
HUT41033A (en) 1987-03-30
IT8620162A0 (it) 1986-04-21
CY1571A (en) 1991-12-20
EG18001A (en) 1991-11-30
DD244557A5 (de) 1987-04-08
DK163584B (da) 1992-03-16
GB2173798B (en) 1988-11-30
BE904646A (fr) 1986-10-21
NO164659C (no) 1990-10-31
FI861634A0 (fi) 1986-04-17
CS270435B2 (en) 1990-06-13
PT82436B (pt) 1988-11-30
LU86402A1 (fr) 1986-11-05
DE3613365A1 (de) 1987-01-02
SE8601825L (sv) 1986-10-23
PT82436A (en) 1986-05-01
DE3613365C2 (sv) 1989-06-15
ZW9086A1 (en) 1986-12-03
NL192205B (nl) 1996-11-01
JPS61249989A (ja) 1986-11-07
IE861048L (en) 1986-10-22
NO861430L (no) 1986-10-23
NL192205C (nl) 1997-03-04
ES554215A0 (es) 1987-10-16
AR242581A1 (es) 1993-04-30
GR861065B (en) 1986-09-01
AU589170B2 (en) 1989-10-05
FI84268C (sv) 1991-11-11
NL8601011A (nl) 1986-11-17
SG90890G (en) 1991-01-18
DK182486A (da) 1986-10-23
YU65986A (en) 1987-12-31
HK106290A (en) 1990-12-28
DK163584C (da) 1992-08-10
JPH0327554B2 (sv) 1991-04-16
CN1015714B (zh) 1992-03-04
DK182486D0 (da) 1986-04-21
AT392072B (de) 1991-01-25
ZM4286A1 (en) 1989-03-27
CN86102630A (zh) 1987-02-04
FR2580652A1 (fr) 1986-10-24
MY100694A (en) 1991-01-17
IT1228241B (it) 1991-06-05
NO164659B (no) 1990-07-23
ATA106786A (de) 1990-07-15
NZ215717A (en) 1989-06-28
ES8800236A1 (es) 1987-10-16
FI861634A (fi) 1986-10-23
CH671399A5 (sv) 1989-08-31
YU43697B (en) 1989-10-31
FR2580652B1 (fr) 1989-01-06
CS287286A2 (en) 1989-11-14
FI84268B (fi) 1991-07-31
SU1435155A3 (ru) 1988-10-30
GB8609661D0 (en) 1986-05-29
HU195223B (en) 1988-04-28
AU5616886A (en) 1986-11-06
ZA862985B (en) 1986-12-30
SE500217C2 (sv) 1994-05-09
OA08245A (fr) 1987-10-30
GB2173798A (en) 1986-10-22

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Legal Events

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