ES8800236A1 - Un procedimiento para obtener acido-7-amino-3-propenilcefalosporanico y sus esteres. - Google Patents
Un procedimiento para obtener acido-7-amino-3-propenilcefalosporanico y sus esteres.Info
- Publication number
- ES8800236A1 ES8800236A1 ES554215A ES554215A ES8800236A1 ES 8800236 A1 ES8800236 A1 ES 8800236A1 ES 554215 A ES554215 A ES 554215A ES 554215 A ES554215 A ES 554215A ES 8800236 A1 ES8800236 A1 ES 8800236A1
- Authority
- ES
- Spain
- Prior art keywords
- acid derivatives
- hydrogen
- cephalosporanic acid
- intermediates
- cephem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YGBFLZPYDUKSPT-MRVPVSSYSA-N cephalosporanic acid Chemical class S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)C[C@H]21 YGBFLZPYDUKSPT-MRVPVSSYSA-N 0.000 title 1
- 229930186147 Cephalosporin Natural products 0.000 abstract 2
- 229940124587 cephalosporin Drugs 0.000 abstract 2
- 150000001780 cephalosporins Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- UBXPJNKEFJVBII-ZTHSNPKKSA-N (6R)-3-[(Z)-2-aminoprop-1-enyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical compound N\C(=C/C=1CS[C@H]2N(C=1C(=O)O)C(C2)=O)\C UBXPJNKEFJVBII-ZTHSNPKKSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72587185A | 1985-04-22 | 1985-04-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES554215A0 ES554215A0 (es) | 1987-10-16 |
ES8800236A1 true ES8800236A1 (es) | 1987-10-16 |
Family
ID=24916301
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES554215A Expired ES8800236A1 (es) | 1985-04-22 | 1986-04-21 | Un procedimiento para obtener acido-7-amino-3-propenilcefalosporanico y sus esteres. |
Country Status (38)
Country | Link |
---|---|
JP (1) | JPS61249989A (sv) |
KR (1) | KR860008189A (sv) |
CN (1) | CN1015714B (sv) |
AR (1) | AR242581A1 (sv) |
AT (1) | AT392072B (sv) |
AU (1) | AU589170B2 (sv) |
BE (1) | BE904646A (sv) |
CA (1) | CA1273629A (sv) |
CH (1) | CH671399A5 (sv) |
CS (1) | CS270435B2 (sv) |
CY (1) | CY1571A (sv) |
DD (1) | DD244557A5 (sv) |
DE (1) | DE3613365A1 (sv) |
DK (1) | DK163584C (sv) |
EG (1) | EG18001A (sv) |
ES (1) | ES8800236A1 (sv) |
FI (1) | FI84268C (sv) |
FR (1) | FR2580652B1 (sv) |
GB (1) | GB2173798B (sv) |
GR (1) | GR861065B (sv) |
HK (1) | HK106290A (sv) |
HU (1) | HU195223B (sv) |
IE (1) | IE59014B1 (sv) |
IT (1) | IT1228241B (sv) |
LU (1) | LU86402A1 (sv) |
MY (1) | MY100694A (sv) |
NL (1) | NL192205C (sv) |
NO (1) | NO164659C (sv) |
NZ (1) | NZ215717A (sv) |
OA (1) | OA08245A (sv) |
PT (1) | PT82436B (sv) |
SE (1) | SE500217C2 (sv) |
SG (1) | SG90890G (sv) |
SU (1) | SU1435155A3 (sv) |
YU (1) | YU43697B (sv) |
ZA (1) | ZA862985B (sv) |
ZM (1) | ZM4286A1 (sv) |
ZW (1) | ZW9086A1 (sv) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4708955A (en) * | 1985-06-24 | 1987-11-24 | Bristol-Myers Company | 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof |
US4870168A (en) * | 1987-02-26 | 1989-09-26 | Bristol-Myers Company | 3-Unsaturated alkyl cephems from 3-triflyl cephems |
DE3933934A1 (de) * | 1989-10-03 | 1991-04-11 | Bayer Ag | Verfahren zur herstellung von 7-amino-3-((z)-1-propen-1-yl)-3-cephem-4-carbonsaeure |
ES2157199T3 (es) * | 1991-03-08 | 2001-08-16 | Biochemie Gmbh | Nuevo procedimiento para la produccion de cefalosporinas y nuevos compuestos intermedios para este procedimiento. |
KR950700311A (ko) | 1992-02-05 | 1995-01-16 | 게오르게스 그렐리니, 한스 루돌프하우스 | 3-세펨-4-카복실산 유도체의 정제방법(Process for the purification of a 3-cephem-4-carboxylic acid derivatives) |
AT399876B (de) * | 1992-02-05 | 1995-08-25 | Biochemie Gmbh | Verfahren zur abreicherung von 7-amino-3-((e)-1- propen-1-yl)-3-cephem-4-carbonsäure |
JPH07173168A (ja) * | 1993-07-14 | 1995-07-11 | Sumitomo Chem Co Ltd | セフェム系化合物、その製法、およびそれのセフェム系抗生物質製造への利用 |
WO2004033464A1 (en) * | 2002-10-08 | 2004-04-22 | Ranbaxy Laboratories Limited | Process for the preparation of (z)-isomer enriched 7-amino-3-propen-1-yl-3-cephem-4- carboxylic acid |
EP1678186A4 (en) * | 2003-10-30 | 2007-04-25 | Cj Corp | PROCESS FOR THE PREPARATION OF CEPHEM DERIVATIVES |
JP4046708B2 (ja) * | 2004-06-04 | 2008-02-13 | 明治製菓株式会社 | 3−アルケニルセフェム化合物の製造方法 |
EP1809638B1 (en) | 2004-11-01 | 2010-02-17 | Hetero Drugs Limited | A novel process for preparation of cefprozil intermediate |
CN103183686B (zh) * | 2011-12-30 | 2016-06-29 | 浙江新和成股份有限公司 | 7β-氨基-7α-甲氧基-3-头孢烯化合物的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4110534A (en) * | 1970-01-23 | 1978-08-29 | Glaxo Laboratories Limited | Process for the preparation of 3-vinyl and substituted vinyl cephalosporins |
US3769277A (en) * | 1970-01-23 | 1973-10-30 | Glaxo Lab Ltd | Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group |
GB1342241A (en) * | 1970-01-23 | 1974-01-03 | Glaxo Lab Ltd | Cephalosporin compounds |
US4065620A (en) * | 1971-06-14 | 1977-12-27 | Eli Lilly And Company | 3-(Substituted) vinyl cephalosporins |
US4409214A (en) * | 1979-11-19 | 1983-10-11 | Fujisawa Pharmaceutical, Co., Ltd. | 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof |
US4520022A (en) * | 1983-01-28 | 1985-05-28 | Bristol-Myers Company | Substituted vinyl cephalosporins |
AU566944B2 (en) * | 1983-10-07 | 1987-11-05 | Gist-Brocades N.V. | Preparation of 3-cephem derivatives |
-
1986
- 1986-03-21 FR FR8604051A patent/FR2580652B1/fr not_active Expired
- 1986-04-07 NZ NZ215717A patent/NZ215717A/xx unknown
- 1986-04-11 NO NO861430A patent/NO164659C/no unknown
- 1986-04-16 AU AU56168/86A patent/AU589170B2/en not_active Expired
- 1986-04-16 SU SU864027263A patent/SU1435155A3/ru active
- 1986-04-17 FI FI861634A patent/FI84268C/sv not_active IP Right Cessation
- 1986-04-17 EG EG219/86A patent/EG18001A/xx active
- 1986-04-18 AR AR86303699A patent/AR242581A1/es active
- 1986-04-18 CA CA000507037A patent/CA1273629A/en not_active Expired - Lifetime
- 1986-04-21 OA OA58840D patent/OA08245A/xx unknown
- 1986-04-21 CN CN86102630A patent/CN1015714B/zh not_active Expired
- 1986-04-21 BE BE0/216572A patent/BE904646A/fr not_active IP Right Cessation
- 1986-04-21 DK DK182486A patent/DK163584C/da not_active IP Right Cessation
- 1986-04-21 LU LU86402A patent/LU86402A1/fr unknown
- 1986-04-21 IT IT8620162A patent/IT1228241B/it active
- 1986-04-21 DD DD86289446A patent/DD244557A5/de unknown
- 1986-04-21 IE IE104886A patent/IE59014B1/en not_active IP Right Cessation
- 1986-04-21 CH CH1601/86A patent/CH671399A5/de not_active IP Right Cessation
- 1986-04-21 PT PT82436A patent/PT82436B/pt unknown
- 1986-04-21 HU HU861664A patent/HU195223B/hu unknown
- 1986-04-21 ZM ZM42/86A patent/ZM4286A1/xx unknown
- 1986-04-21 DE DE19863613365 patent/DE3613365A1/de active Granted
- 1986-04-21 ES ES554215A patent/ES8800236A1/es not_active Expired
- 1986-04-21 CS CS862872A patent/CS270435B2/cs not_active IP Right Cessation
- 1986-04-21 ZA ZA862985A patent/ZA862985B/xx unknown
- 1986-04-21 NL NL8601011A patent/NL192205C/nl not_active IP Right Cessation
- 1986-04-21 GB GB08609661A patent/GB2173798B/en not_active Expired
- 1986-04-21 SE SE8601825A patent/SE500217C2/sv not_active IP Right Cessation
- 1986-04-21 ZW ZW90/86A patent/ZW9086A1/xx unknown
- 1986-04-22 JP JP61091419A patent/JPS61249989A/ja active Granted
- 1986-04-22 YU YU659/86A patent/YU43697B/xx unknown
- 1986-04-22 GR GR861065A patent/GR861065B/el unknown
- 1986-04-22 AT AT0106786A patent/AT392072B/de not_active IP Right Cessation
- 1986-04-22 KR KR1019860003085A patent/KR860008189A/ko not_active Application Discontinuation
-
1987
- 1987-09-29 MY MYPI87002270A patent/MY100694A/en unknown
-
1990
- 1990-11-09 SG SG908/90A patent/SG90890G/en unknown
- 1990-12-18 HK HK1062/90A patent/HK106290A/xx not_active IP Right Cessation
-
1991
- 1991-12-20 CY CY1571A patent/CY1571A/xx unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20070625 |