JPS6442490A - Substituted oxycarbonylaminocephem compound - Google Patents

Substituted oxycarbonylaminocephem compound

Info

Publication number
JPS6442490A
JPS6442490A JP20051387A JP20051387A JPS6442490A JP S6442490 A JPS6442490 A JP S6442490A JP 20051387 A JP20051387 A JP 20051387A JP 20051387 A JP20051387 A JP 20051387A JP S6442490 A JPS6442490 A JP S6442490A
Authority
JP
Japan
Prior art keywords
substituted
acid
compound
oxycarbonylaminocephem
oxycarbonylaminocepha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP20051387A
Other languages
Japanese (ja)
Other versions
JP2648862B2 (en
Inventor
Shoji Tsuji
Tetsuo Okada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Priority to JP62200513A priority Critical patent/JP2648862B2/en
Publication of JPS6442490A publication Critical patent/JPS6442490A/en
Application granted granted Critical
Publication of JP2648862B2 publication Critical patent/JP2648862B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound expressed by the formula (R<1> represents alkyl, aralkyl or aryl; R<2> represents H or carbamoyl which may be protected; R<3> represents H or ester). EXAMPLE:7-t-butoxycarbonylaminocepholosporanic acid. USE:An intermediate for synthesis of cephalosporin compounds useful as an antibacterial agent, etc. PREPARATION:(A) The corresponding 7-substituted-oxycarbonylaminocepha losporanic acid is hydrolyzed with alkanol-water-alkali metal hydroxide and (B) thus obtained corresponding 7-substituted-oxycarbonyl-amino-3- hydroxymethylcephem-4-carboxylic acid is carbamoylated. (C) The corresponding 7-substituted-oxycarbonylamino-3-carbamoyloxymethylcephem-4-carboxyic acid is then esterified to afford the aimed cephem compound.
JP62200513A 1987-08-10 1987-08-10 Preparation of substituted oxycarbonylaminocephem compounds Expired - Fee Related JP2648862B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62200513A JP2648862B2 (en) 1987-08-10 1987-08-10 Preparation of substituted oxycarbonylaminocephem compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62200513A JP2648862B2 (en) 1987-08-10 1987-08-10 Preparation of substituted oxycarbonylaminocephem compounds

Publications (2)

Publication Number Publication Date
JPS6442490A true JPS6442490A (en) 1989-02-14
JP2648862B2 JP2648862B2 (en) 1997-09-03

Family

ID=16425561

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62200513A Expired - Fee Related JP2648862B2 (en) 1987-08-10 1987-08-10 Preparation of substituted oxycarbonylaminocephem compounds

Country Status (1)

Country Link
JP (1) JP2648862B2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4862789A (en) * 1971-11-29 1973-09-01
JPS62149684A (en) * 1985-09-27 1987-07-03 Takeda Chem Ind Ltd Antibacterial compound

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4862789A (en) * 1971-11-29 1973-09-01
JPS62149684A (en) * 1985-09-27 1987-07-03 Takeda Chem Ind Ltd Antibacterial compound

Also Published As

Publication number Publication date
JP2648862B2 (en) 1997-09-03

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Legal Events

Date Code Title Description
LAPS Cancellation because of no payment of annual fees