BRPI0821859A2 - Composição para cuidado oral, uso de um aminoácido básico, em forma livre ou de sal, e, método para aumentar a distribuição de um agente antibacteriano em uma composição para cuidado oral - Google Patents

Composição para cuidado oral, uso de um aminoácido básico, em forma livre ou de sal, e, método para aumentar a distribuição de um agente antibacteriano em uma composição para cuidado oral

Info

Publication number
BRPI0821859A2
BRPI0821859A2 BRPI0821859-5A2A BRPI0821859A BRPI0821859A2 BR PI0821859 A2 BRPI0821859 A2 BR PI0821859A2 BR PI0821859 A BRPI0821859 A BR PI0821859A BR PI0821859 A2 BRPI0821859 A2 BR PI0821859A2
Authority
BR
Brazil
Prior art keywords
oral care
care composition
salt
distribution
increasing
Prior art date
Application number
BRPI0821859-5A2A
Other languages
English (en)
Inventor
Michael Prencipe
Ravi Subramanyam
Sarita V Mello
Donghui Wu
Suman K Chopra
Andre M Morgan
Diane Cummins
Richard J Sullivan
Ralph Peter Santarpia Iii
Lynette Zaidel
Qin Wang
Gary Edward Tambs
Virginia Monsul Barnes
Rajnish Kohli
Richard Scott Robinson
Sergio Leite
Eric A Simon
Original Assignee
Colgate Palmolive Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40056156&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0821859(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Colgate Palmolive Co filed Critical Colgate Palmolive Co
Publication of BRPI0821859A2 publication Critical patent/BRPI0821859A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • A61K8/21Fluorides; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24Phosphorous; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/28Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/54Polymers characterized by specific structures/properties
    • A61K2800/542Polymers characterized by specific structures/properties characterized by the charge
    • A61K2800/5424Polymers characterized by specific structures/properties characterized by the charge anionic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/596Mixtures of surface active compounds
BRPI0821859-5A2A 2008-02-08 2008-03-28 Composição para cuidado oral, uso de um aminoácido básico, em forma livre ou de sal, e, método para aumentar a distribuição de um agente antibacteriano em uma composição para cuidado oral BRPI0821859A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US2743208P 2008-02-08 2008-02-08
US2743108P 2008-02-08 2008-02-08
US2742008P 2008-02-08 2008-02-08
PCT/US2008/058704 WO2009099454A1 (en) 2008-02-08 2008-03-28 Oral care product and methods of use and manufacture thereof

Publications (1)

Publication Number Publication Date
BRPI0821859A2 true BRPI0821859A2 (pt) 2014-09-30

Family

ID=40056156

Family Applications (3)

Application Number Title Priority Date Filing Date
BRPI0821974-5A BRPI0821974B1 (pt) 2008-02-08 2008-03-28 Composição para cuidado oral, método para preparar uma composição para cuidado oral, uso da composição oral e uso de um sal de um aminoácido básico
BRPI0821859-5A2A BRPI0821859A2 (pt) 2008-02-08 2008-03-28 Composição para cuidado oral, uso de um aminoácido básico, em forma livre ou de sal, e, método para aumentar a distribuição de um agente antibacteriano em uma composição para cuidado oral
BRPI0822121-9A2A BRPI0822121A2 (pt) 2008-02-08 2008-03-28 Composição para cuidado oral, e uso da mesma

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BRPI0821974-5A BRPI0821974B1 (pt) 2008-02-08 2008-03-28 Composição para cuidado oral, método para preparar uma composição para cuidado oral, uso da composição oral e uso de um sal de um aminoácido básico

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0822121-9A2A BRPI0822121A2 (pt) 2008-02-08 2008-03-28 Composição para cuidado oral, e uso da mesma

Country Status (19)

Country Link
US (4) US9682026B2 (pt)
EP (5) EP2384740A3 (pt)
JP (4) JP5580747B2 (pt)
CN (6) CN101938978A (pt)
AR (3) AR065884A1 (pt)
AU (3) AU2008349850B2 (pt)
BR (3) BRPI0821974B1 (pt)
CA (4) CA2828861A1 (pt)
CL (3) CL2008000894A1 (pt)
CO (3) CO6382103A2 (pt)
MX (4) MX357344B (pt)
MY (3) MY149730A (pt)
PA (4) PA8774401A1 (pt)
PE (4) PE20091399A1 (pt)
RU (2) RU2619865C2 (pt)
SA (1) SA08290182B1 (pt)
TW (5) TWI426924B (pt)
WO (3) WO2009099455A1 (pt)
ZA (2) ZA201003675B (pt)

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11857588B2 (en) 2005-04-05 2024-01-02 Membrane Protective Technologies, Inc. Reproductive cell maintenance system
US9919014B2 (en) * 2005-04-05 2018-03-20 Membrane Protective Technologies, Inc. Reproductive cell maintenance system
CN101801521B (zh) 2007-05-14 2015-06-17 纽约州立大学研究基金会 生物膜中细菌细胞内的生理学分散响应诱导
EP2384740A3 (en) 2008-02-08 2016-05-18 Colgate-Palmolive Company Oral care product and methods of use and manufacture thereof
RU2476890C2 (ru) 2008-02-08 2013-02-27 Колгейт-Палмолив Компани Способы и системы для ухода за ротовой полостью
US8568697B2 (en) 2008-03-21 2013-10-29 Colgate-Palmolive Company High fluoride ion recovery compositions
US20090238769A1 (en) * 2008-03-21 2009-09-24 Colgate-Palmolive Company Compositions Comprising Nonionic And Zwittterionic Surfactants
AR080076A1 (es) 2010-01-29 2012-03-14 Colgate Palmolive Co Producto de cuidado oral para el cuidado de esmalte sensible
JP5769795B2 (ja) 2010-03-31 2015-08-26 コルゲート・パーモリブ・カンパニーColgate−Palmolive Company 口腔ケア組成物
RU2537035C2 (ru) 2010-03-31 2014-12-27 Колгейт-Палмолив Компани Композиция для ухода за полостью рта
MX2012012860A (es) * 2010-06-01 2012-11-29 Colgate Palmolive Co Composiciones para el cuidado oral resistentes al crecimiento microbiano.
CN105748305A (zh) * 2010-06-23 2016-07-13 高露洁-棕榄公司 治疗用口腔组合物
JP5723001B2 (ja) 2010-06-23 2015-05-27 コルゲート・パーモリブ・カンパニーColgate−Palmolive Company 治療用口腔用組成物
SG187733A1 (en) 2010-08-07 2013-03-28 Univ New York State Res Found Oral compositions comprising a zinc compound and an anti-microbial agent
AU2010359375B2 (en) * 2010-08-18 2014-01-30 Colgate-Palmolive Company Oral care product and methods of use and manufacture thereof
BR112013010519A2 (pt) * 2010-10-27 2016-07-05 Colgate Palmolive Co composição de higiene oral compreendendo arginina e carbonato de cálcio
CA2815636C (en) 2010-11-12 2016-12-06 Colgate-Palmolive Company Oral care product and methods of use and manufacture thereof
SG189862A1 (en) * 2010-11-12 2013-06-28 Colgate Palmolive Co Oral care product and methods of use and manufacture thereof
US9717929B2 (en) 2010-12-07 2017-08-01 Colgate-Palmolive Company Dentifrice compositions containing calcium silicate and a basic amino acid
RU2597841C2 (ru) * 2010-12-20 2016-09-20 Колгейт-Палмолив Компани Неводная композиция по уходу за полостью рта, содержащая активные агенты окклюзии зубов
SG190860A1 (en) 2010-12-20 2013-07-31 Colgate Palmolive Co Gelatin encapsulated oral care composition containing dental occlusion actives, hydrophobic viscosity modifier and oil carrier
WO2013019953A2 (en) * 2011-08-02 2013-02-07 The Procter & Gamble Company Water-soluble surfactant compositions having improved taste
AU2011383327B2 (en) * 2011-12-15 2015-05-14 Colgate-Palmolive Company Oral care compositions
CN107648070A (zh) 2011-12-15 2018-02-02 高露洁-棕榄公司 水性口腔护理组合物
TW201338791A (zh) 2011-12-19 2013-10-01 Colgate Palmolive Co 液體活化系統
CA2859164A1 (en) * 2011-12-21 2013-06-27 Colgate-Palmolive Company Oral care compositions
CN102846488A (zh) * 2012-09-17 2013-01-02 江苏隆力奇生物科技股份有限公司 一种牙齿美化液
MX351254B (es) * 2012-12-03 2017-10-06 Colgate Palmolive Co Composiciones y metodos para el tratamiento de la caries dental.
MX350570B (es) 2012-12-03 2017-09-11 Colgate Palmolive Co Composiciones para cuidado oral que comprenden carbonato de calcio y un sistema conservador basado en alcohol bencílico o ácido benzoico, y un alquilen glicol.
KR20150092759A (ko) * 2012-12-05 2015-08-13 콜게이트-파아므올리브캄파니 인산 아연 함유 조성물
KR20150092255A (ko) * 2012-12-05 2015-08-12 콜게이트-파아므올리브캄파니 플루오라이드-안정 아연을 함유하는 조성물
KR20150094676A (ko) * 2012-12-06 2015-08-19 콜게이트-파아므올리브캄파니 아연 함유 조성물용 계면활성제 시스템
RU2642620C2 (ru) 2012-12-18 2018-01-25 Колгейт-Палмолив Компани Стабильные композиции, содержащие ион металла
WO2014098828A1 (en) 2012-12-19 2014-06-26 Colgate-Palmolive Company Teeth whitening methods, visually perceptible signals and compositions therefor|comprising zinc amino acid halides
JP6007780B2 (ja) * 2012-12-20 2016-10-12 ライオン株式会社 口腔用組成物及び口腔バイオフィルム除去剤
JP2016503036A (ja) * 2012-12-24 2016-02-01 コルゲート・パーモリブ・カンパニーColgate−Palmolive Company オーラルケア組成物
JP6351985B2 (ja) * 2013-01-30 2018-07-04 株式会社 ソーシン 口腔用組成物
CN103304684B (zh) * 2013-06-28 2015-07-15 四川柯森油田化学有限公司 一种提取纯化透明质酸的生产方法
US10543163B2 (en) * 2013-12-03 2020-01-28 Colgate-Palmolive Company Oral care compositions
CN104721063B (zh) 2013-12-19 2018-05-08 高露洁-棕榄公司 包含氧化锌和柠檬酸锌的洁齿剂组合物
CN104721226B (zh) 2013-12-19 2019-12-24 高露洁-棕榄公司 口腔护理组合物
MX365970B (es) * 2013-12-27 2019-06-21 Colgate Palmolive Co Composiciones para cuidado oral prebioticas que contienen acidos carboxilicos.
JP6751349B2 (ja) * 2014-04-10 2020-09-02 ビーエーエスエフ ソシエタス・ヨーロピアBasf Se 口腔ケア組成物
RU2017104238A (ru) * 2014-07-11 2018-08-13 Конинклейке Филипс Н.В. Система для состава по уходу за полостью рта, обеспечивающая аморфный фосфат кальция
US9370476B2 (en) * 2014-09-29 2016-06-21 The Research Foundation For The State University Of New York Compositions and methods for altering human cutaneous microbiome to increase growth of Staphylococcus epidermidis and reduce Staphylococcus aureus proliferation
JP5764712B1 (ja) * 2014-12-16 2015-08-19 株式会社松風 歯質再生剤
MX2017007420A (es) 2014-12-18 2017-11-06 Colgate Palmolive Co Composiciones para el cuidado bucal con alto contenido de agua y micro resistencia.
US10123956B2 (en) 2014-12-23 2018-11-13 Colgate-Palmolive Company Oral care compositions
EP3217951B1 (en) * 2014-12-23 2019-04-03 Colgate-Palmolive Company Oral care composition
BR112017012807B1 (pt) 2014-12-26 2020-09-15 Colgate-Palmolive Company Composição para higiene bucal e uso de um complexo solúvel de polifosfato de zinco na preparação da mesma
JP2015221814A (ja) * 2015-07-10 2015-12-10 コルゲート・パーモリブ・カンパニーColgate−Palmolive Company オーラルケア製品およびその使用法および製造法
JP2016006102A (ja) * 2015-08-14 2016-01-14 コルゲート・パーモリブ・カンパニーColgate−Palmolive Company 口腔ケア製品およびその使用方法および製造方法
US10959922B2 (en) * 2015-09-28 2021-03-30 Evonik Operations Gmbh Silica-based antimicrobial oral compositions
BR112018008196B1 (pt) * 2015-11-13 2021-05-04 The Procter & Gamble Company composições dentifrícias com benefícios antitártaro e antibacterianos
CN113975184A (zh) * 2015-11-13 2022-01-28 宝洁公司 具有改善的消费者体验的洁齿剂组合物
AU2016381976B2 (en) * 2015-12-31 2019-12-19 Colgate-Palmolive Company Cleansing compositions
CN107969115B (zh) 2016-06-24 2021-12-24 高露洁-棕榄公司 口腔护理组合物及使用方法
CN114306100A (zh) * 2016-08-11 2022-04-12 高露洁-棕榄公司 口腔护理组合物
US10058493B2 (en) 2016-12-21 2018-08-28 Colgate-Palmolive Company Oral care compositions and methods of use
CA3046655A1 (en) * 2016-12-27 2018-07-05 Colgate-Palmolive Company Dual-phase mouthwashes comprising cpc, and a preservative system comprised of potassium sorbate, sodium benzoate and benzyl alcohol
WO2018166673A1 (en) * 2017-03-13 2018-09-20 Unilever Plc Oral care compositions
WO2018165707A1 (en) * 2017-03-14 2018-09-20 The University Of Melbourne Complexes for treating sensitivity
EP3727600B1 (en) * 2017-12-19 2023-09-20 Colgate-Palmolive Company Amino acid carbamate complexes
SE543703C2 (en) 2018-03-05 2021-06-15 Arevo Ab Separation of basic amino acids
WO2019183876A1 (en) 2018-03-29 2019-10-03 The Procter & Gamble Company Oral care compositions for promoting gum health
JP7058342B2 (ja) * 2018-03-29 2022-04-21 ザ プロクター アンド ギャンブル カンパニー 歯肉健康を促進するための口腔ケア組成物
CA3095054C (en) 2018-03-29 2023-05-02 The Procter & Gamble Company Oral care compositions comprising a stannous ion source and an amino acid for promoting gum health
JP7058343B2 (ja) 2018-03-29 2022-04-21 ザ プロクター アンド ギャンブル カンパニー 歯肉健康を促進するための口腔ケア組成物
GB201811061D0 (en) * 2018-07-05 2018-08-22 GlaxoSmithKline Consumer Healthcare UK IP Ltd Novel composition
GB201811065D0 (en) * 2018-07-05 2018-08-22 GlaxoSmithKline Consumer Healthcare UK IP Ltd Novel composition
CN109091401A (zh) * 2018-10-02 2018-12-28 张旱莲 一种抗牙本质过敏的组合物
CN109381350A (zh) * 2018-11-20 2019-02-26 湖北中医药大学 一种含虎杖牙膏及其制备方法
CN113015561A (zh) * 2018-11-27 2021-06-22 高露洁-棕榄公司 具有释放部件的口腔护理器具
CN113056309A (zh) * 2018-11-27 2021-06-29 高露洁-棕榄公司 具有释放组分的口腔护理器具
US11857653B2 (en) * 2018-12-17 2024-01-02 Johnson & Johnson Consumer Inc. Method of providing an oral care benefit using a poorly-soluble calcium compound and fluoride
MX2021007100A (es) 2018-12-20 2021-08-11 Colgate Palmolive Co Composicion para el cuidado oral que comprende zinc y un aminoacido para tratar los sintomas de un trastorno gastrico en la cavidad bucal.
US20220040072A1 (en) * 2018-12-26 2022-02-10 Colgate-Palmolive Company Reduction of Pathogenic Bacteria Using Arginine
EP3930672A1 (en) 2019-03-29 2022-01-05 Colgate-Palmolive Company Oral care product and methods of use and manufacture thereof
MX2021011553A (es) * 2019-03-29 2021-10-26 Colgate Palmolive Co Producto para el cuidado bucal y metodos para uso y fabricacion de este.
CN110226633A (zh) * 2019-05-17 2019-09-13 浙江国际海运职业技术学院 一种富硒牡蛎小分子蛋白肽固体饮料及其制备方法
CA3141204A1 (en) * 2019-06-28 2020-12-30 Colgate-Palmolive Company Oral care compositions and methods of use
BR112022004332A2 (pt) 2019-09-30 2022-05-31 Procter & Gamble Composições dentifrícias para o tratamento de biofilme dental
WO2021062607A1 (en) 2019-09-30 2021-04-08 The Procter & Gamble Company Oral care compositions comprising hops beta acid and amino acid
CA3155478A1 (en) 2019-09-30 2021-04-08 The Procter & Gamble Company Oral care compositions comprising hops beta acid and metal ion
CA3155865A1 (en) 2019-09-30 2021-04-08 The Procter & Gamble Company TOOTHPASTE COMPOSITIONS FOR TREATING DENTAL BIOFILM
EP4017457A1 (en) * 2019-11-15 2022-06-29 Colgate-Palmolive Company Oral care compositions
MX2022006600A (es) * 2019-12-06 2022-07-05 Colgate Palmolive Co Producto para el cuidado bucal y metodos de uso y fabricacion de este.
WO2021168684A1 (en) * 2020-02-26 2021-09-02 The Procter & Gamble Company Oral care compositions for gum health
MX2022011465A (es) * 2020-03-24 2022-10-07 Colgate Palmolive Co Metodos mejorados para la fabricacion de dentifrico con arginina.
WO2021195590A1 (en) 2020-03-27 2021-09-30 Colgate-Palmolive Company Oral care compositions and methods of use
WO2022026672A1 (en) * 2020-07-31 2022-02-03 Colgate-Palmolive Company Process for producing an oral care composition
KR102275526B1 (ko) * 2020-09-24 2021-07-08 김효선 구강 관리용 치약
WO2022251228A1 (en) 2021-05-25 2022-12-01 Colgate-Palmolive Company Oral care compositions
CN113546210A (zh) * 2021-07-23 2021-10-26 振德医疗用品股份有限公司 一种口腔正畸过程中预防龋病的粉末敷料及其制备方法
WO2023069123A1 (en) * 2021-10-20 2023-04-27 3M Innovative Properties Company Phosphate and arginine containing compositions and the delivery of such compositions for virulence suppression
CN113830398A (zh) * 2021-10-29 2021-12-24 南京鼓楼医院 一种便携式漱口套装
CN115463043A (zh) * 2022-08-25 2022-12-13 克劳丽化妆品股份有限公司 一种口腔护理组合物及漱口水

Family Cites Families (133)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US391177A (en) * 1888-10-16 Screw-press
US3538230A (en) * 1966-12-05 1970-11-03 Lever Brothers Ltd Oral compositions containing silica xerogels as cleaning and polishing agents
US3678154A (en) * 1968-07-01 1972-07-18 Procter & Gamble Oral compositions for calculus retardation
US3535421A (en) 1968-07-11 1970-10-20 Procter & Gamble Oral compositions for calculus retardation
US4152418A (en) 1970-04-01 1979-05-01 Lever Brothers Company Zinc and enzyme mouthwash and mouthwash concentrate for reducing dental plaque and calculus formation
US3696191A (en) 1970-11-10 1972-10-03 Monsanto Co Dental creams containing enzymes
US3943241A (en) 1971-08-30 1976-03-09 General Mills, Inc. Cariostatic composition
US3932608A (en) 1971-08-30 1976-01-13 General Mills, Inc. Food composition
US4058595A (en) 1971-10-13 1977-11-15 Colgate-Palmolive Company Stabilized toothpastes containing an enzyme
US3932605A (en) 1972-06-12 1976-01-13 Jaroslav Vit Dental treatment
US3988434A (en) 1972-08-07 1976-10-26 Schole Murray L Dental preparation
US3959458A (en) * 1973-02-09 1976-05-25 The Procter & Gamble Company Oral compositions for calculus retardation
US3937807A (en) 1973-03-06 1976-02-10 The Procter & Gamble Company Oral compositions for plaque, caries, and calculus retardation with reduced staining tendencies
US4025616A (en) 1973-03-06 1977-05-24 The Procter & Gamble Company Oral compositions for plaque, caries and calculus retardation with reduced staining tendencies
US3862307A (en) * 1973-04-09 1975-01-21 Procter & Gamble Dentifrices containing a cationic therapeutic agent and improved silica abrasive
US4100269A (en) 1973-06-28 1978-07-11 Lever Brothers Company Anticalculus dentifrice
US4022880A (en) 1973-09-26 1977-05-10 Lever Brothers Company Anticalculus composition
US3925543A (en) 1973-11-01 1975-12-09 Colgate Palmolive Co Antibacterial oral compositions containing preservative-antioxidants
US3991177A (en) 1973-11-27 1976-11-09 Colgate-Palmolive Company Oral compositions containing dextranase
CA1063357A (en) * 1974-05-21 1979-10-02 James J. Benedict Abrasive composition
US4011309A (en) 1975-01-20 1977-03-08 Marion Laboratories, Inc. Dentifrice composition and method for desensitizing sensitive teeth
US4051234A (en) 1975-06-06 1977-09-27 The Procter & Gamble Company Oral compositions for plaque, caries, and calculus retardation with reduced staining tendencies
US4064138A (en) * 1975-11-12 1977-12-20 General Mills, Inc. Amino acid derivatives
ZA773318B (en) 1976-06-18 1978-04-26 I Kleinberg Means and method for improving natural defenses against caries
USRE31181E (en) 1976-06-18 1983-03-15 Means and method for improving natural defenses against caries
US4042680A (en) 1976-08-02 1977-08-16 Indiana University Foundation Anticariogenic maloaluminate complexes
US4108981A (en) 1976-08-02 1978-08-22 Indiana University Foundation Alkaline oral compositions comprising aluminum and a carboxylic acid
US4108979A (en) 1976-08-02 1978-08-22 Indiana University Foundation Dentifrice preparations comprising aluminum and a compatible abrasive
US4146607A (en) 1977-11-07 1979-03-27 Lever Brothers Company Synergistic anti-plaque mixture with tetradecylamine plus aluminum and/or zinc
US4160821A (en) 1978-02-27 1979-07-10 Johnson & Johnson Treatment for gingivitis
US4213961A (en) 1978-03-23 1980-07-22 Beecham, Inc. Oral compositions
GB1573727A (en) 1978-05-19 1980-08-28 Colgate Palmolive Co Dentifrices
US4216961A (en) 1978-08-04 1980-08-12 Mcquillan Mary J Table baseball apparatus
US4183915A (en) * 1978-10-13 1980-01-15 Colgate-Palmolive Company Stable solution for dental remineralization
US4225579A (en) 1979-02-27 1980-09-30 Israel Kleinberg Means and method for improving defenses against caries
US4340583A (en) * 1979-05-23 1982-07-20 J. M. Huber Corporation High fluoride compatibility dentifrice abrasives and compositions
US4339432A (en) 1979-06-20 1982-07-13 Lever Brothers Company Oral mouthwash containing zinc and glycine
US4269822A (en) 1979-07-20 1981-05-26 Laclede Professional Products, Inc. Antiseptic dentifrice
JPS5846483B2 (ja) 1979-09-20 1983-10-17 ライオン株式会社 口腔用組成物
JPS5835965B2 (ja) 1979-07-31 1983-08-05 ライオン株式会社 口腔用組成物
US4355022A (en) 1981-07-01 1982-10-19 Interon, Inc. Method of dental treatment
US4532124A (en) 1981-08-19 1985-07-30 Development Finance Corporation Of New Zealand Dental rinse
US4375526A (en) * 1981-11-20 1983-03-01 Calgon Corporation Anionic polymers for reduction of viscosity of a magnesium hydroxide filter cake paste
JPS58118509A (ja) 1981-12-29 1983-07-14 Lion Corp 口腔用組成物
US4885155A (en) 1982-06-22 1989-12-05 The Procter & Gamble Company Anticalculus compositions using pyrophosphate salt
JPS6092208A (ja) * 1983-10-25 1985-05-23 Kao Corp 塩化ナトリウム含有歯磨組成物
US4725576A (en) 1983-12-29 1988-02-16 Research Foundation Of State University Of New York Fungicidal polypeptide compositions containing L-histidine and methods for use therefore
US4528181A (en) 1984-02-01 1985-07-09 Colgate-Palmolive Company Dentifrice containing dual sources of fluoride
US5334617A (en) 1984-03-19 1994-08-02 The Rockefeller University Amino acids useful as inhibitors of the advanced glycosylation of proteins
GB8411731D0 (en) 1984-05-09 1984-06-13 Unilever Plc Oral compositions
US5000939A (en) 1984-06-12 1991-03-19 Colgate-Palmolive Company Dentifrice containing stabilized enzyme
JPH0742219B2 (ja) 1984-07-26 1995-05-10 ライオン株式会社 口腔用組成物
US4538990A (en) 1984-09-24 1985-09-03 Medical College Of Ga. Research Institute, Inc. Method of decreasing the permeability of a dental cavity
US5192530A (en) * 1987-01-30 1993-03-09 Colgate-Palmolive Company Antibacterial antiplaque oral composition
US5192531A (en) * 1988-12-29 1993-03-09 Colgate-Palmolive Company Antibacterial antiplaque oral composition
US5032386A (en) * 1988-12-29 1991-07-16 Colgate-Palmolive Company Antiplaque antibacterial oral composition
US5188821A (en) 1987-01-30 1993-02-23 Colgate-Palmolive Company Antibacterial antiplaque oral composition mouthwash or liquid dentifrice
US5043154A (en) * 1987-01-30 1991-08-27 Colgate-Palmolive Co. Antibacterial, antiplaque, anticalculus oral composition
CH671879A5 (pt) * 1987-02-26 1989-10-13 Nestle Sa
US4866161A (en) 1987-08-24 1989-09-12 University Of South Alabama Inhibition of tartar deposition by polyanionic/hydrophobic peptides and derivatives thereof which have a clustered block copolymer structure
US5004597A (en) * 1987-09-14 1991-04-02 The Procter & Gamble Company Oral compositions comprising stannous flouride and stannous gluconate
GB8729564D0 (en) 1987-12-18 1988-02-03 Unilever Plc Oral compositions
US4842847A (en) 1987-12-21 1989-06-27 The B. F. Goodrich Company Dental calculus inhibiting compositions
US5438076A (en) 1988-05-03 1995-08-01 Perio Products, Ltd. Liquid polymer composition, and method of use
US4948580A (en) * 1988-12-08 1990-08-14 E. R. Squibb & Sons, Inc. Muco-bioadhesive composition
US5334375A (en) 1988-12-29 1994-08-02 Colgate Palmolive Company Antibacterial antiplaque oral composition
SU1754104A1 (ru) 1989-01-05 1992-08-15 Одесский научно-исследовательский институт стоматологии Зубной порошок
SE512333C2 (sv) * 1989-08-25 2000-02-28 Colgate Palmolive Co Antibakteriell oral komposition med plack- och tandstensbegränsande verkan
US4954137A (en) * 1989-12-19 1990-09-04 Shell Oil Company Inhibition of sulfide inclusion in slag
US5197531A (en) 1990-06-13 1993-03-30 Leybold Aktiengesellschaft Method of manufacturing directionally solidified castings
JP2806024B2 (ja) * 1990-09-19 1998-09-30 ライオン株式会社 口腔用組成物
US5096700A (en) 1990-09-28 1992-03-17 The Procter & Gamble Company Halogenated aminohexanoates and aminobutyrates antimicrobial agents
US5356615A (en) 1991-01-30 1994-10-18 Colgate Palmolive Company Antiplaque oral compositions
US5154815A (en) * 1991-10-23 1992-10-13 Xerox Corporation Method of forming integral electroplated filters on fluid handling devices such as ink jet printheads
US5370865A (en) 1992-05-15 1994-12-06 Kao Corporation Composition for use in oral cavity
JP2627709B2 (ja) * 1992-05-15 1997-07-09 花王株式会社 口腔用組成物
US5286480A (en) 1992-06-29 1994-02-15 The Procter & Gamble Company Use of N-acetylated amino acid complexes in oral care compositions
DE4306673A1 (de) * 1993-03-04 1994-09-08 Hoechst Ag Verfahren zur Herstellung eines für den Einsatz in Zahnpasten geeigneten Dicalciumphosphat-Dihydrats
JP3566374B2 (ja) * 1994-02-03 2004-09-15 花王株式会社 口腔用組成物
JP3803695B2 (ja) * 1994-11-28 2006-08-02 サンスター株式会社 抗菌製剤
JP3389719B2 (ja) * 1994-12-22 2003-03-24 ライオン株式会社 口腔用組成物
WO1997002802A1 (en) 1995-07-10 1997-01-30 Unilever N.V. Self-heating dentifrice
US5762911A (en) 1996-03-05 1998-06-09 The Research Foundation Of State University Of New York Anti-caries oral compositions
US6488961B1 (en) 1996-09-20 2002-12-03 Ethypharm, Inc. Effervescent granules and methods for their preparation
JPH10245328A (ja) * 1997-03-04 1998-09-14 Kao Corp 粉状歯磨組成物
US5906811A (en) 1997-06-27 1999-05-25 Thione International, Inc. Intra-oral antioxidant preparations
US6221341B1 (en) * 1997-11-19 2001-04-24 Oraceutical Llc Tooth whitening compositions
US5922346A (en) 1997-12-01 1999-07-13 Thione International, Inc. Antioxidant preparation
FI116642B (fi) 1998-02-09 2006-01-13 Nokia Corp Puheparametrien käsittelymenetelmä, puhekoodauksen käsittely-yksikkö ja verkkoelementti
JPH11246374A (ja) * 1998-02-25 1999-09-14 Lion Corp 口腔用組成物
US6805883B2 (en) * 1998-03-12 2004-10-19 Mars, Incorporated Food products containing polyphenol(s) and L-arginine to stimulate nitric oxide
AUPP494798A0 (en) * 1998-07-29 1998-08-20 Pacific Biolink Pty Limited Protective protein formulation
US5997301A (en) 1998-10-20 1999-12-07 Linden; Lars Ake Treatment of tooth surfaces and substances therefor
FR2785534A1 (fr) * 1998-11-09 2000-05-12 Rhodia Chimie Sa Composition dentifrice fluoree comprenant des particules abrasives de materiau calcique compatibles avec le fluor
JP2000229825A (ja) * 1999-02-05 2000-08-22 Lion Corp 口腔用組成物
US6436370B1 (en) 1999-06-23 2002-08-20 The Research Foundation Of State University Of New York Dental anti-hypersensitivity composition and method
JP3977553B2 (ja) * 1999-09-02 2007-09-19 花王株式会社 液状口腔用組成物
DE59911342D1 (de) * 1999-10-08 2005-01-27 Coty Bv Kosmetische wirkstoffzubereitung mit synergistisch erhöhtem radikalschutzfaktor
US6558654B2 (en) 2000-04-11 2003-05-06 Mclaughlin Gerald Composition and method for whitening teeth
US6290933B1 (en) 2000-05-09 2001-09-18 Colgate-Palmolive Company High cleaning dentifrice
US6500409B1 (en) 2000-05-10 2002-12-31 Colgate Palmolive Company Synergistic antiplaque/antigingivitis oral composition
US8283135B2 (en) * 2000-06-30 2012-10-09 The Procter & Gamble Company Oral care compositions containing combinations of anti-bacterial and host-response modulating agents
US6485950B1 (en) * 2000-07-14 2002-11-26 Council Of Scientific And Industrial Research Isozyme of autoclavable superoxide dismutase (SOD), a process for the identification and extraction of the SOD in cosmetic, food and pharmaceutical compositions
DE60037282T2 (de) * 2000-10-25 2008-10-16 The Procter & Gamble Company, Cincinnati Zahnpflegemittel
DE10130163B4 (de) 2000-11-21 2012-01-12 Siemens Ag Anordnung zur Verminderung kohlenstoffhaltiger Partikelemissionen von Dieselmotoren
US20020081360A1 (en) 2000-12-27 2002-06-27 Andreas Burgard Salts of L-amino acid having improved taste and their preparation
PL363310A1 (en) * 2001-04-24 2004-11-15 Specialty Minerals (Michigan) Inc. Fluoride compatible calcium carbonate
ATE525113T1 (de) * 2001-07-05 2011-10-15 Sunstar Inc Orales präparat
PL373913A1 (en) * 2001-10-02 2005-09-19 Unilever N.V. Oral composition comprising fine ground natural chalk
DE60138971D1 (de) * 2001-11-15 2009-07-23 Miret Lab Verwendung von kationischem tensid zur verstärkung der antimikrobiellen aktivität in deodorants und mundpflegemitteln
ATE388689T1 (de) 2002-04-30 2008-03-15 Cognis Ip Man Gmbh Verwendung von wirkstoffmischungen mit azelainsäure und glycyrrhetinsäure als anti- aknemittel
JP2004244404A (ja) * 2002-12-19 2004-09-02 Lion Corp 練歯磨組成物
US20040185027A1 (en) * 2003-02-21 2004-09-23 Reierson Robert Lee Anti-sensitivity, anti-caries, anti-staining, anti-plaque, ultra-mild oral hygiene agent
US20040220264A1 (en) * 2003-03-17 2004-11-04 Yu Ruey J Bioavailability and improved delivery of acidic pharmaceutical drugs
JP4852223B2 (ja) 2003-06-20 2012-01-11 花王株式会社 口腔細菌の共凝集抑制剤
JP4934266B2 (ja) 2003-07-09 2012-05-16 花王株式会社 口腔用組成物
DE10340542A1 (de) * 2003-09-01 2005-03-24 Henkel Kgaa Mund- und Zahnpflegemittel
JP5586816B2 (ja) 2004-03-15 2014-09-10 大正製薬株式会社 亜鉛化合物配合組成物
RU2287318C2 (ru) * 2004-05-28 2006-11-20 Сергей Павлович Соловьев Средство для ухода за кожей, волосами, ногтями, полостью рта человека, улучшающее их состояние и внешний вид
KR100993123B1 (ko) * 2005-07-12 2010-11-08 콜게이트-파아므올리브캄파니 활성 작용제를 분배하는 저장통을 가진 구강 건강관리 기구
US20070014740A1 (en) 2005-07-15 2007-01-18 Colgate-Palmolive Company Oral compositions having cationic active ingredients
GB0525369D0 (en) * 2005-12-14 2006-01-18 Ineos Silicas Ltd Silicas
US20070140990A1 (en) * 2005-12-21 2007-06-21 Nataly Fetissova Oral Compositions Comprising Propolis
US20070258916A1 (en) 2006-04-14 2007-11-08 Oregon Health & Science University Oral compositions for treating tooth hypersensitivity
US20070298069A1 (en) * 2006-06-26 2007-12-27 Boston Scientific Scimed, Inc. Medical devices for release of low solubility therapeutic agents
US9682256B2 (en) * 2006-07-14 2017-06-20 Colgate-Palmolive Company Methods of making compositions comprising films
CN100531884C (zh) * 2006-07-20 2009-08-26 中国科学院理化技术研究所 烷基芳苄基聚氧乙烯醚阴离子型表面活性剂及其制备方法与用途
TWI566782B (zh) 2008-02-08 2017-01-21 美國棕欖公司 口腔保健產品及其使用方法與製造
CN101938979B (zh) 2008-02-08 2014-11-26 高露洁-棕榄公司 口腔护理方案
MX337177B (es) 2008-02-08 2016-02-16 Colgate Palmolive Co Sales de arginina y sus usos para el tratamiento de enfermedades en la cavidad oral.
MX2010005542A (es) 2008-02-08 2010-06-22 Colgate Palmolive Co Producto para el cuidado oral y metodos de uso y fabricacion del mismo.
EP2384740A3 (en) 2008-02-08 2016-05-18 Colgate-Palmolive Company Oral care product and methods of use and manufacture thereof
US8281597B2 (en) 2008-12-31 2012-10-09 General Electric Company Cooled flameholder swirl cup

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