BRPI0115910B8 - medicamento compreendendo 5-[(r)-2-(5,6-dietil-indan-2ilamino)-1-hidróxi-etil]-8-hidróxi-1h-quinolin-2-ona e corticóides para o tratamento de doencas inflamatórias ou obstrutivas das vias aéreas - Google Patents

medicamento compreendendo 5-[(r)-2-(5,6-dietil-indan-2ilamino)-1-hidróxi-etil]-8-hidróxi-1h-quinolin-2-ona e corticóides para o tratamento de doencas inflamatórias ou obstrutivas das vias aéreas

Info

Publication number
BRPI0115910B8
BRPI0115910B8 BRPI0115910A BRPI0115910B8 BR PI0115910 B8 BRPI0115910 B8 BR PI0115910B8 BR PI0115910 A BRPI0115910 A BR PI0115910A BR PI0115910 B8 BRPI0115910 B8 BR PI0115910B8
Authority
BR
Brazil
Prior art keywords
hydroxy
treatment
2ylamino
indan
quinolin
Prior art date
Application number
Other languages
English (en)
Portuguese (pt)
Inventor
Cuenoud Bernard
Lowther Nicholas
Alec Fairhurst Robin
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR0115910A publication Critical patent/BR0115910A/pt
Publication of BRPI0115910B1 publication Critical patent/BRPI0115910B1/pt
Publication of BRPI0115910B8 publication Critical patent/BRPI0115910B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0115910 2000-12-04 2001-12-03 medicamento compreendendo 5-[(r)-2-(5,6-dietil-indan-2ilamino)-1-hidróxi-etil]-8-hidróxi-1h-quinolin-2-ona e corticóides para o tratamento de doencas inflamatórias ou obstrutivas das vias aéreas BRPI0115910B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0029562.6A GB0029562D0 (en) 2000-12-04 2000-12-04 Organic compounds
PCT/EP2001/014122 WO2002045703A2 (en) 2000-12-04 2001-12-03 Mixtures or organic compounds for the treatmentof airway diseases

Publications (3)

Publication Number Publication Date
BR0115910A BR0115910A (pt) 2004-01-20
BRPI0115910B1 BRPI0115910B1 (pt) 2019-12-31
BRPI0115910B8 true BRPI0115910B8 (pt) 2021-05-25

Family

ID=9904414

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0115910 BRPI0115910B8 (pt) 2000-12-04 2001-12-03 medicamento compreendendo 5-[(r)-2-(5,6-dietil-indan-2ilamino)-1-hidróxi-etil]-8-hidróxi-1h-quinolin-2-ona e corticóides para o tratamento de doencas inflamatórias ou obstrutivas das vias aéreas

Country Status (27)

Country Link
US (5) US6800643B2 (enExample)
EP (2) EP1341542B1 (enExample)
JP (2) JP2004514739A (enExample)
KR (1) KR100523541B1 (enExample)
CN (1) CN1212119C (enExample)
AT (1) ATE361077T1 (enExample)
AU (2) AU2002217082B2 (enExample)
BR (1) BRPI0115910B8 (enExample)
CA (1) CA2427282C (enExample)
CY (1) CY1106727T1 (enExample)
CZ (1) CZ304294B6 (enExample)
DE (1) DE60128258T2 (enExample)
DK (1) DK1341542T3 (enExample)
EC (1) ECSP034620A (enExample)
ES (1) ES2284732T3 (enExample)
GB (1) GB0029562D0 (enExample)
HU (1) HU229552B1 (enExample)
IL (2) IL155709A0 (enExample)
MX (1) MXPA03004976A (enExample)
NO (1) NO325692B1 (enExample)
NZ (1) NZ525731A (enExample)
PL (1) PL204002B1 (enExample)
PT (1) PT1341542E (enExample)
RU (1) RU2292890C2 (enExample)
SK (1) SK287331B6 (enExample)
WO (1) WO2002045703A2 (enExample)
ZA (1) ZA200303399B (enExample)

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US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
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CA2728523C (en) 2008-06-20 2020-03-10 Mannkind Corporation An interactive apparatus and method for real-time profiling of inhalation efforts
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
PT3111927T (pt) 2009-05-29 2020-03-03 Pearl Therapeutics Inc Composições para administração respiratória de agentes ativos e métodos e sistemas associados
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KR100940388B1 (ko) * 2009-07-01 2010-02-02 유병덕 스크류탈수기 및 이를 포함하는 유기성폐기물 건조장치
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
CN110237260A (zh) * 2010-07-16 2019-09-17 希普拉有限公司 包含r(+)布地奈德和一种或多种支气管扩张剂的药物组合物
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Also Published As

Publication number Publication date
US20040038951A1 (en) 2004-02-26
EP1341542B1 (en) 2007-05-02
US20120108555A1 (en) 2012-05-03
MXPA03004976A (es) 2003-09-05
HU229552B1 (en) 2014-01-28
US20100068288A1 (en) 2010-03-18
RU2292890C2 (ru) 2007-02-10
DE60128258T2 (de) 2007-12-27
HUP0302571A3 (en) 2005-05-30
AU2002217082B2 (en) 2005-04-07
CA2427282A1 (en) 2002-06-13
EP1772142A3 (en) 2011-09-14
RU2003119549A (ru) 2005-02-10
EP1341542A2 (en) 2003-09-10
GB0029562D0 (en) 2001-01-17
JP2007302684A (ja) 2007-11-22
KR100523541B1 (ko) 2005-10-25
HK1059564A1 (en) 2004-07-09
PL204002B1 (pl) 2009-12-31
CA2427282C (en) 2010-10-19
IL155709A (en) 2008-11-26
DK1341542T3 (da) 2007-09-03
CY1106727T1 (el) 2012-05-23
ATE361077T1 (de) 2007-05-15
AU1708202A (en) 2002-06-18
EP1772142A2 (en) 2007-04-11
IL155709A0 (en) 2003-11-23
NO20032510D0 (no) 2003-06-03
BR0115910A (pt) 2004-01-20
ZA200303399B (en) 2004-04-23
KR20030048065A (ko) 2003-06-18
US20060052352A1 (en) 2006-03-09
NO20032510L (no) 2003-06-03
NO325692B1 (no) 2008-07-07
US7622484B2 (en) 2009-11-24
HUP0302571A2 (hu) 2003-11-28
PT1341542E (pt) 2007-08-01
SK287331B6 (sk) 2010-07-07
ECSP034620A (es) 2003-06-25
CN1477963A (zh) 2004-02-25
BRPI0115910B1 (pt) 2019-12-31
DE60128258D1 (de) 2007-06-14
JP2004514739A (ja) 2004-05-20
WO2002045703A2 (en) 2002-06-13
CZ304294B6 (cs) 2014-02-19
US6800643B2 (en) 2004-10-05
CZ20031537A3 (cs) 2003-10-15
PL362443A1 (en) 2004-11-02
SK6502003A3 (en) 2003-12-02
ES2284732T3 (es) 2007-11-16
US20050009795A1 (en) 2005-01-13
NZ525731A (en) 2004-11-26
WO2002045703A3 (en) 2003-03-13
US7008951B2 (en) 2006-03-07
CN1212119C (zh) 2005-07-27

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