BR112015010948A2 - meios de cultura de células - Google Patents

meios de cultura de células

Info

Publication number
BR112015010948A2
BR112015010948A2 BR112015010948A BR112015010948A BR112015010948A2 BR 112015010948 A2 BR112015010948 A2 BR 112015010948A2 BR 112015010948 A BR112015010948 A BR 112015010948A BR 112015010948 A BR112015010948 A BR 112015010948A BR 112015010948 A2 BR112015010948 A2 BR 112015010948A2
Authority
BR
Brazil
Prior art keywords
cell culture
culture media
tyrosine
cysteine
inorganic
Prior art date
Application number
BR112015010948A
Other languages
English (en)
Other versions
BR112015010948B1 (pt
Inventor
Jasper Christian
Von Hagen Joerg
André Breuning Marcel
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Priority to BR122020000038-4A priority Critical patent/BR122020000038B1/pt
Publication of BR112015010948A2 publication Critical patent/BR112015010948A2/pt
Publication of BR112015010948B1 publication Critical patent/BR112015010948B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0025—Culture media for plant cell or plant tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C12N2500/33—Amino acids other than alpha-amino carboxylic acids, e.g. beta-amino acids, taurine

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

resumo patente de invenção: "meios de cultura de células". a presente invenção refere-se a meios de cultura de células que compreendem derivados de ésteres inorgânicos de tirosina e/ou de cisteína. a fraca solubilidade da tirosina e a estabilidade frequentemente não suficiente da cisteína em meios de cultura de células são superadas através da substituição das mesmas por um derivado de éster inorgânico, por exemplo, por um derivado fosforilado.
BR112015010948-9A 2012-11-14 2013-11-14 Processo em batelada alimentada para a cultura de células em um biorreator BR112015010948B1 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122020000038-4A BR122020000038B1 (pt) 2012-11-14 2013-11-14 Meio de cultura de células compreendendo o ácido (s)-2-amino-3 - sulfossulfanilpropanóico, processo para cultivar células e processo em batelada alimentada para a cultura de células em um biorreator

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12007711 2012-11-14
EP12007711.0 2012-11-14
PCT/EP2013/003441 WO2014075807A1 (en) 2012-11-14 2013-11-14 Cell culture med

Publications (2)

Publication Number Publication Date
BR112015010948A2 true BR112015010948A2 (pt) 2017-07-11
BR112015010948B1 BR112015010948B1 (pt) 2021-10-26

Family

ID=47189690

Family Applications (2)

Application Number Title Priority Date Filing Date
BR112015010948-9A BR112015010948B1 (pt) 2012-11-14 2013-11-14 Processo em batelada alimentada para a cultura de células em um biorreator
BR122020000038-4A BR122020000038B1 (pt) 2012-11-14 2013-11-14 Meio de cultura de células compreendendo o ácido (s)-2-amino-3 - sulfossulfanilpropanóico, processo para cultivar células e processo em batelada alimentada para a cultura de células em um biorreator

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR122020000038-4A BR122020000038B1 (pt) 2012-11-14 2013-11-14 Meio de cultura de células compreendendo o ácido (s)-2-amino-3 - sulfossulfanilpropanóico, processo para cultivar células e processo em batelada alimentada para a cultura de células em um biorreator

Country Status (13)

Country Link
US (2) US10030225B2 (pt)
EP (2) EP3401319B1 (pt)
JP (2) JP6433429B2 (pt)
KR (1) KR102170858B1 (pt)
CN (1) CN104812891B (pt)
AR (2) AR093460A1 (pt)
BR (2) BR112015010948B1 (pt)
CA (2) CA2891279C (pt)
DK (2) DK3401319T3 (pt)
ES (1) ES2827701T3 (pt)
MX (1) MX358095B (pt)
SG (2) SG11201503579RA (pt)
WO (1) WO2014075807A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR093460A1 (es) * 2012-11-14 2015-06-10 Merck Patent Ges Mit Beschränkter Haftung Medios de cultivo celular
CN106146360B (zh) * 2015-03-31 2020-05-15 深圳翰宇药业股份有限公司 一种制备酪氨酸-o-磺酸盐的方法
ES2838693T3 (es) * 2015-07-30 2021-07-02 Merck Patent Gmbh Método para aumentar el nivel de glutatión en células
CN107849527A (zh) * 2015-08-05 2018-03-27 默克专利股份公司 生产细胞培养基的方法
DK3430072T3 (da) * 2016-03-17 2020-08-31 Merck Patent Gmbh Fremgangsmåde til oprensning af poloxamerer
EP3448871B1 (en) * 2016-04-28 2023-10-11 Merck Patent GmbH Method for reducing the trisulfide level in proteins
WO2018018613A1 (zh) 2016-07-29 2018-02-01 广东东阳光药业有限公司 一种提高抗体纯度的细胞培养基和培养方法
WO2019004293A1 (ja) * 2017-06-27 2019-01-03 味の素株式会社 リボフラビン誘導体含有培地
CN110945118A (zh) * 2017-07-28 2020-03-31 日产化学株式会社 培养基添加用组合物及培养基添加用化合物以及使用了它们的细胞或组织的培养方法
US20210171901A1 (en) * 2017-11-16 2021-06-10 Life Technologies Corporation Streamlined methods for making liquid media
CN108823173A (zh) * 2018-07-24 2018-11-16 郑州伊美诺生物技术有限公司 用于杂交瘤细胞培养的补料培养基及其制备方法
CN109053797B (zh) * 2018-09-05 2021-06-29 成都百事兴科技实业有限公司 一种氧磷酸-l-酪氨酸的改进合成方法
CN112969783A (zh) 2018-11-12 2021-06-15 赢创运营有限公司 包含酮酸的培养基
CN111304144B (zh) * 2019-11-30 2023-04-07 河南普诺易生物制品研究院有限公司 一种昆虫细胞培养基及其制备方法
WO2023120637A1 (ja) * 2021-12-24 2023-06-29 味の素株式会社 動物細胞培養用の組成物
WO2023190692A1 (ja) * 2022-03-30 2023-10-05 富士フイルム株式会社 混合粉体の製造方法、混合粉体、粉体、及び、粉体培地
CN115305208A (zh) * 2022-09-16 2022-11-08 苏州星寰生物科技有限公司 一种米根霉固态发酵培养基及其制备方法

Family Cites Families (11)

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JPS55144896A (en) * 1979-04-24 1980-11-12 Takeda Chem Ind Ltd Preparation of cephalosporin antibiotic
WO1995022599A1 (fr) * 1994-02-18 1995-08-24 Teijin Limited Procede de mise en culture de cellules animales
DE10117834B4 (de) * 2001-04-03 2005-10-27 Eberhard-Karls-Universität Tübingen Universitätsklinikum Verwendung von Phosphotyrosin zum Schutz von biologischem Material sowie kosmetische Zusammensetzung und Kultivierungsmedium
JP4303595B2 (ja) 2001-12-21 2009-07-29 透 小池 アニオン性置換基を有する物質を捕捉可能な亜鉛錯体
GB0208041D0 (en) * 2002-04-08 2002-05-22 Lonza Biologics Plc Method of culturing animal cells
WO2006062238A1 (ja) * 2004-12-07 2006-06-15 Ajinomoto Co., Inc. アミノ酸の微粉末及びその懸濁液
TW201516149A (zh) 2006-09-13 2015-05-01 Abbvie Inc 細胞培養改良
KR20140130512A (ko) * 2008-03-06 2014-11-10 할로자임, 아이엔씨 가용성 히알루로니다아제의 대규모 제조
JP5359409B2 (ja) * 2009-03-12 2013-12-04 味の素株式会社 Ｌ−システイン生産菌及びｌ−システインの製造法
EP2414530A1 (en) * 2009-04-03 2012-02-08 DSM Sinochem Pharmaceuticals Netherlands B.V. Fermentation process
AR093460A1 (es) * 2012-11-14 2015-06-10 Merck Patent Ges Mit Beschränkter Haftung Medios de cultivo celular

Also Published As

Publication number Publication date
JP2015535423A (ja) 2015-12-14
CA3112061C (en) 2022-08-09
JP6433429B2 (ja) 2018-12-05
CN104812891B (zh) 2018-10-12
CA2891279A1 (en) 2014-05-22
DK3401319T3 (da) 2020-09-07
WO2014075807A1 (en) 2014-05-22
US10030225B2 (en) 2018-07-24
CA3112061A1 (en) 2014-05-22
MX2015006099A (es) 2015-08-06
EP2920296A1 (en) 2015-09-23
ES2827701T3 (es) 2021-05-24
SG11201503579RA (en) 2015-06-29
EP3401319A1 (en) 2018-11-14
AR117697A2 (es) 2021-08-25
US20150337258A1 (en) 2015-11-26
CN104812891A (zh) 2015-07-29
SG10201811616SA (en) 2019-02-27
JP2019030334A (ja) 2019-02-28
CA2891279C (en) 2022-01-25
EP3401319B1 (en) 2020-07-22
US20180230422A1 (en) 2018-08-16
MX358095B (es) 2018-08-06
AR093460A1 (es) 2015-06-10
KR102170858B1 (ko) 2020-10-28
US10619131B2 (en) 2020-04-14
KR20150085834A (ko) 2015-07-24
JP6650011B2 (ja) 2020-02-19
BR122020000038B1 (pt) 2021-11-03
DK2920296T3 (en) 2018-10-22
EP2920296B1 (en) 2018-07-18
BR112015010948B1 (pt) 2021-10-26

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/11/2013, OBSERVADAS AS CONDICOES LEGAIS.