AR117697A2 - Medios de cultivo celular - Google Patents

Medios de cultivo celular

Info

Publication number
AR117697A2
AR117697A2 ARP190103670A ARP190103670A AR117697A2 AR 117697 A2 AR117697 A2 AR 117697A2 AR P190103670 A ARP190103670 A AR P190103670A AR P190103670 A ARP190103670 A AR P190103670A AR 117697 A2 AR117697 A2 AR 117697A2
Authority
AR
Argentina
Prior art keywords
cell culture
culture media
tyrosine
cysteine
inorganic
Prior art date
Application number
ARP190103670A
Other languages
English (en)
Inventor
Jasper Christian Dr
Breuning Marcel Andr Dr
Von Hagen Joerg Dr
Original Assignee
Merck Patent Ges Mit Beschraenkter Haftung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Ges Mit Beschraenkter Haftung filed Critical Merck Patent Ges Mit Beschraenkter Haftung
Publication of AR117697A2 publication Critical patent/AR117697A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0025—Culture media for plant cell or plant tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C12N2500/33—Amino acids other than alpha-amino carboxylic acids, e.g. beta-amino acids, taurine

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente se refiere a medios de cultivo celular que comprenden derivados de éster inorgánicos de tirosina y/o cisteína. La pobre solubilidad de tirosina y la a veces no suficiente estabilidad de cisteína en medios de cultivo celular se supera sustituyéndolos con un derivado de éster inorgánico, por ejemplo, con un derivado fosforilado. Reivindicación 1: Medio de cultivo celular caracterizado porque comprende ácido (S)-2-amino-3-sulfosulfanil-propiónico o sus sales. Reivindicación 8: Proceso para cultivar células, caracterizado porque comprende a) proporcionar un biorreactor, b) mezclar las células por cultivar con un medio de cultivo celular de acuerdo con una o varias de las reivindicaciones 1 a 7, c) incubar la mezcla de la etapa b).
ARP190103670A 2012-11-14 2019-12-13 Medios de cultivo celular AR117697A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12007711 2012-11-14

Publications (1)

Publication Number Publication Date
AR117697A2 true AR117697A2 (es) 2021-08-25

Family

ID=47189690

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP130104164A AR093460A1 (es) 2012-11-14 2013-11-13 Medios de cultivo celular
ARP190103670A AR117697A2 (es) 2012-11-14 2019-12-13 Medios de cultivo celular

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP130104164A AR093460A1 (es) 2012-11-14 2013-11-13 Medios de cultivo celular

Country Status (13)

Country Link
US (2) US10030225B2 (es)
EP (2) EP3401319B1 (es)
JP (2) JP6433429B2 (es)
KR (1) KR102170858B1 (es)
CN (1) CN104812891B (es)
AR (2) AR093460A1 (es)
BR (2) BR122020000038B1 (es)
CA (2) CA3112061C (es)
DK (2) DK2920296T3 (es)
ES (1) ES2827701T3 (es)
MX (2) MX377520B (es)
SG (2) SG10201811616SA (es)
WO (1) WO2014075807A1 (es)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR093460A1 (es) * 2012-11-14 2015-06-10 Merck Patent Ges Mit Beschränkter Haftung Medios de cultivo celular
CN106146360B (zh) * 2015-03-31 2020-05-15 深圳翰宇药业股份有限公司 一种制备酪氨酸-o-磺酸盐的方法
JP6845218B2 (ja) * 2015-07-30 2021-03-17 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ 細胞におけるグルタチオンレベルを増加させる方法
DK3331986T3 (da) * 2015-08-05 2020-08-31 Merck Patent Gmbh Fremgangsmåde til fremstilling af celledyrkningsmedium
WO2017157505A1 (en) * 2016-03-17 2017-09-21 Merck Patent Gmbh Method for purifying poloxamers
ES2967868T3 (es) 2016-04-28 2024-05-06 Merck Patent Gmbh Método para reducir el nivel de trisulfuro en proteínas
WO2018018613A1 (zh) 2016-07-29 2018-02-01 广东东阳光药业有限公司 一种提高抗体纯度的细胞培养基和培养方法
CA3068685A1 (en) 2017-06-27 2019-01-03 Ajinomoto Co., Inc. Riboflavin derivative-containing medium
AU2018307555A1 (en) * 2017-07-28 2020-02-27 Nissan Chemical Corporation Additive composition for culture medium, additive compound for culture medium, and method for culture of cells or tissue using same
EP3710574A1 (en) 2017-11-16 2020-09-23 Life Technologies Corporation Streamlined methods for making liquid media
CN108823173A (zh) * 2018-07-24 2018-11-16 郑州伊美诺生物技术有限公司 用于杂交瘤细胞培养的补料培养基及其制备方法
CN109053797B (zh) * 2018-09-05 2021-06-29 成都百事兴科技实业有限公司 一种氧磷酸-l-酪氨酸的改进合成方法
EP3880800A1 (en) * 2018-11-12 2021-09-22 Evonik Operations GmbH Culture medium comprising keto acids
US20220220430A1 (en) * 2019-05-23 2022-07-14 Bristol-Myers Squibb Company Methods of monitoring cell culture media
CN114641562B (zh) * 2019-11-14 2025-07-08 默克专利股份公司 细胞培养基
CN111304144B (zh) * 2019-11-30 2023-04-07 河南普诺易生物制品研究院有限公司 一种昆虫细胞培养基及其制备方法
EP4077371B1 (en) * 2019-12-19 2024-01-10 Merck Patent GmbH Methods and compositions for modulating the glycosylation profile of proteins
EP4455263A4 (en) * 2021-12-24 2025-12-03 Ajinomoto Kk COMPOSITION FOR ANIMAL CELL CULTURE
WO2023190692A1 (ja) * 2022-03-30 2023-10-05 富士フイルム株式会社 混合粉体の製造方法、混合粉体、粉体、及び、粉体培地
CN118900910A (zh) * 2022-03-30 2024-11-05 富士胶片株式会社 混合粉体的制造方法、混合粉体、粉体及粉体培养基
CN115305208A (zh) * 2022-09-16 2022-11-08 苏州星寰生物科技有限公司 一种米根霉固态发酵培养基及其制备方法

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
JPS55144896A (en) * 1979-04-24 1980-11-12 Takeda Chem Ind Ltd Preparation of cephalosporin antibiotic
US5824552A (en) * 1994-02-18 1998-10-20 Teijin Limited Medium for culturing animal cells
DE10117834B4 (de) * 2001-04-03 2005-10-27 Eberhard-Karls-Universität Tübingen Universitätsklinikum Verwendung von Phosphotyrosin zum Schutz von biologischem Material sowie kosmetische Zusammensetzung und Kultivierungsmedium
JP4303595B2 (ja) 2001-12-21 2009-07-29 透 小池 アニオン性置換基を有する物質を捕捉可能な亜鉛錯体
GB0208041D0 (en) * 2002-04-08 2002-05-22 Lonza Biologics Plc Method of culturing animal cells
EP1839502A4 (en) 2004-12-07 2010-03-24 Ajinomoto Kk FINE AMINO ACID POWDER AND SUSPENSION THEREOF
BRPI0716762A2 (pt) 2006-09-13 2013-09-24 Abbott Lab melhorias da cultura celular
EP4269578B8 (en) * 2008-03-06 2024-07-17 Halozyme, Inc. Soluble hyaluronidase composition
JP5359409B2 (ja) * 2009-03-12 2013-12-04 味の素株式会社 Ｌ−システイン生産菌及びｌ−システインの製造法
EP2414530A1 (en) * 2009-04-03 2012-02-08 DSM Sinochem Pharmaceuticals Netherlands B.V. Fermentation process
AR093460A1 (es) * 2012-11-14 2015-06-10 Merck Patent Ges Mit Beschränkter Haftung Medios de cultivo celular

Also Published As

Publication number Publication date
AR093460A1 (es) 2015-06-10
JP2019030334A (ja) 2019-02-28
MX377520B (es) 2025-03-10
SG11201503579RA (en) 2015-06-29
DK2920296T3 (en) 2018-10-22
BR112015010948A2 (pt) 2017-07-11
WO2014075807A1 (en) 2014-05-22
US10619131B2 (en) 2020-04-14
KR102170858B1 (ko) 2020-10-28
CA2891279C (en) 2022-01-25
EP3401319A1 (en) 2018-11-14
JP6433429B2 (ja) 2018-12-05
DK3401319T3 (da) 2020-09-07
CA3112061C (en) 2022-08-09
MX2015006099A (es) 2015-08-06
BR122020000038B1 (pt) 2021-11-03
US20180230422A1 (en) 2018-08-16
BR112015010948B1 (pt) 2021-10-26
CA3112061A1 (en) 2014-05-22
CA2891279A1 (en) 2014-05-22
CN104812891B (zh) 2018-10-12
EP2920296A1 (en) 2015-09-23
JP2015535423A (ja) 2015-12-14
EP3401319B1 (en) 2020-07-22
ES2827701T3 (es) 2021-05-24
US20150337258A1 (en) 2015-11-26
JP6650011B2 (ja) 2020-02-19
EP2920296B1 (en) 2018-07-18
CN104812891A (zh) 2015-07-29
SG10201811616SA (en) 2019-02-27
MX358095B (es) 2018-08-06
KR20150085834A (ko) 2015-07-24
US10030225B2 (en) 2018-07-24

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