AR117697A2 - Medios de cultivo celular - Google Patents
Medios de cultivo celularInfo
- Publication number
- AR117697A2 AR117697A2 ARP190103670A ARP190103670A AR117697A2 AR 117697 A2 AR117697 A2 AR 117697A2 AR P190103670 A ARP190103670 A AR P190103670A AR P190103670 A ARP190103670 A AR P190103670A AR 117697 A2 AR117697 A2 AR 117697A2
- Authority
- AR
- Argentina
- Prior art keywords
- cell culture
- culture media
- tyrosine
- cysteine
- inorganic
- Prior art date
Links
- 230000001413 cellular effect Effects 0.000 title 1
- 239000001963 growth medium Substances 0.000 title 1
- 239000006143 cell culture medium Substances 0.000 abstract 4
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 abstract 2
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 2
- 235000018417 cysteine Nutrition 0.000 abstract 2
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 abstract 2
- NOKPBJYHPHHWAN-UWTATZPHSA-N (2s)-2-amino-3-sulfosulfanylpropanoic acid Chemical compound OC(=O)[C@H](N)CSS(O)(=O)=O NOKPBJYHPHHWAN-UWTATZPHSA-N 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- -1 cysteine ester Chemical class 0.000 abstract 1
- 150000002485 inorganic esters Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0025—Culture media for plant cell or plant tissue culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
- C12N2500/33—Amino acids other than alpha-amino carboxylic acids, e.g. beta-amino acids, taurine
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La presente se refiere a medios de cultivo celular que comprenden derivados de éster inorgánicos de tirosina y/o cisteína. La pobre solubilidad de tirosina y la a veces no suficiente estabilidad de cisteína en medios de cultivo celular se supera sustituyéndolos con un derivado de éster inorgánico, por ejemplo, con un derivado fosforilado. Reivindicación 1: Medio de cultivo celular caracterizado porque comprende ácido (S)-2-amino-3-sulfosulfanil-propiónico o sus sales. Reivindicación 8: Proceso para cultivar células, caracterizado porque comprende a) proporcionar un biorreactor, b) mezclar las células por cultivar con un medio de cultivo celular de acuerdo con una o varias de las reivindicaciones 1 a 7, c) incubar la mezcla de la etapa b).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12007711 | 2012-11-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR117697A2 true AR117697A2 (es) | 2021-08-25 |
Family
ID=47189690
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130104164A AR093460A1 (es) | 2012-11-14 | 2013-11-13 | Medios de cultivo celular |
| ARP190103670A AR117697A2 (es) | 2012-11-14 | 2019-12-13 | Medios de cultivo celular |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130104164A AR093460A1 (es) | 2012-11-14 | 2013-11-13 | Medios de cultivo celular |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10030225B2 (es) |
| EP (2) | EP2920296B1 (es) |
| JP (2) | JP6433429B2 (es) |
| KR (1) | KR102170858B1 (es) |
| CN (1) | CN104812891B (es) |
| AR (2) | AR093460A1 (es) |
| BR (2) | BR112015010948B1 (es) |
| CA (2) | CA3112061C (es) |
| DK (2) | DK3401319T3 (es) |
| ES (1) | ES2827701T3 (es) |
| MX (1) | MX358095B (es) |
| SG (2) | SG10201811616SA (es) |
| WO (1) | WO2014075807A1 (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR093460A1 (es) * | 2012-11-14 | 2015-06-10 | Merck Patent Ges Mit Beschränkter Haftung | Medios de cultivo celular |
| CN106146360B (zh) * | 2015-03-31 | 2020-05-15 | 深圳翰宇药业股份有限公司 | 一种制备酪氨酸-o-磺酸盐的方法 |
| EP3328410B1 (en) * | 2015-07-30 | 2020-09-23 | Merck Patent GmbH | Method for increasing the glutathione level in cells |
| EP3331986B1 (en) * | 2015-08-05 | 2020-07-01 | Merck Patent GmbH | Process for producing cell culture media |
| EP3430072B1 (en) * | 2016-03-17 | 2020-07-01 | Merck Patent GmbH | Method for purifying poloxamers |
| JP7253381B2 (ja) * | 2016-04-28 | 2023-04-06 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | タンパク質中のトリスルフィドレベルを減少させるための方法 |
| WO2018018613A1 (zh) | 2016-07-29 | 2018-02-01 | 广东东阳光药业有限公司 | 一种提高抗体纯度的细胞培养基和培养方法 |
| EP3647411A4 (en) * | 2017-06-27 | 2021-05-12 | Ajinomoto Co., Inc. | MEDIUM WITH RIBOFLAVIN DERIVATIVE |
| CA3071363A1 (en) * | 2017-07-28 | 2019-01-31 | Nissan Chemical Corporation | Additive composition for culture medium, additive compound for culture medium, and method for culture of cells or tissue using same |
| US20210171901A1 (en) * | 2017-11-16 | 2021-06-10 | Life Technologies Corporation | Streamlined methods for making liquid media |
| CN108823173A (zh) * | 2018-07-24 | 2018-11-16 | 郑州伊美诺生物技术有限公司 | 用于杂交瘤细胞培养的补料培养基及其制备方法 |
| CN109053797B (zh) * | 2018-09-05 | 2021-06-29 | 成都百事兴科技实业有限公司 | 一种氧磷酸-l-酪氨酸的改进合成方法 |
| WO2020099225A1 (en) | 2018-11-12 | 2020-05-22 | Evonik Operations Gmbh | Culture medium comprising keto acids |
| CN111304144B (zh) * | 2019-11-30 | 2023-04-07 | 河南普诺易生物制品研究院有限公司 | 一种昆虫细胞培养基及其制备方法 |
| WO2023120637A1 (ja) * | 2021-12-24 | 2023-06-29 | 味の素株式会社 | 動物細胞培養用の組成物 |
| WO2023190692A1 (ja) * | 2022-03-30 | 2023-10-05 | 富士フイルム株式会社 | 混合粉体の製造方法、混合粉体、粉体、及び、粉体培地 |
| CN115305208A (zh) * | 2022-09-16 | 2022-11-08 | 苏州星寰生物科技有限公司 | 一种米根霉固态发酵培养基及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55144896A (en) * | 1979-04-24 | 1980-11-12 | Takeda Chem Ind Ltd | Preparation of cephalosporin antibiotic |
| DK0756003T3 (da) * | 1994-02-18 | 2000-02-07 | Teijin Ltd | Fremgangsmåde til dyrkning af dyreceller |
| DE10117834B4 (de) * | 2001-04-03 | 2005-10-27 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Verwendung von Phosphotyrosin zum Schutz von biologischem Material sowie kosmetische Zusammensetzung und Kultivierungsmedium |
| JP4303595B2 (ja) | 2001-12-21 | 2009-07-29 | 透 小池 | アニオン性置換基を有する物質を捕捉可能な亜鉛錯体 |
| GB0208041D0 (en) | 2002-04-08 | 2002-05-22 | Lonza Biologics Plc | Method of culturing animal cells |
| WO2006062238A1 (ja) * | 2004-12-07 | 2006-06-15 | Ajinomoto Co., Inc. | アミノ酸の微粉末及びその懸濁液 |
| WO2008033517A2 (en) * | 2006-09-13 | 2008-03-20 | Abbott Laboratories | Cell culture improvements |
| US8187855B2 (en) * | 2008-03-06 | 2012-05-29 | Halozyme, Inc. | Large-scale production of soluble hyaluronidase |
| JP5359409B2 (ja) * | 2009-03-12 | 2013-12-04 | 味の素株式会社 | Ｌ−システイン生産菌及びｌ−システインの製造法 |
| CN102369290A (zh) * | 2009-04-03 | 2012-03-07 | 帝斯曼知识产权资产管理有限公司 | 发酵工艺 |
| AR093460A1 (es) * | 2012-11-14 | 2015-06-10 | Merck Patent Ges Mit Beschränkter Haftung | Medios de cultivo celular |
-
2013
- 2013-11-13 AR ARP130104164A patent/AR093460A1/es active IP Right Grant
- 2013-11-14 DK DK18178711.0T patent/DK3401319T3/da active
- 2013-11-14 JP JP2015542187A patent/JP6433429B2/ja active Active
- 2013-11-14 CA CA3112061A patent/CA3112061C/en active Active
- 2013-11-14 US US14/442,821 patent/US10030225B2/en active Active
- 2013-11-14 MX MX2015006099A patent/MX358095B/es active IP Right Grant
- 2013-11-14 BR BR112015010948-9A patent/BR112015010948B1/pt active IP Right Grant
- 2013-11-14 KR KR1020157015699A patent/KR102170858B1/ko active IP Right Grant
- 2013-11-14 EP EP13792261.3A patent/EP2920296B1/en active Active
- 2013-11-14 EP EP18178711.0A patent/EP3401319B1/en active Active
- 2013-11-14 WO PCT/EP2013/003441 patent/WO2014075807A1/en active Application Filing
- 2013-11-14 CN CN201380058205.9A patent/CN104812891B/zh active Active
- 2013-11-14 SG SG10201811616SA patent/SG10201811616SA/en unknown
- 2013-11-14 BR BR122020000038-4A patent/BR122020000038B1/pt active IP Right Grant
- 2013-11-14 CA CA2891279A patent/CA2891279C/en active Active
- 2013-11-14 ES ES18178711T patent/ES2827701T3/es active Active
- 2013-11-14 DK DK13792261.3T patent/DK2920296T3/en active
- 2013-11-14 SG SG11201503579RA patent/SG11201503579RA/en unknown
-
2018
- 2018-04-13 US US15/952,874 patent/US10619131B2/en active Active
- 2018-11-06 JP JP2018208858A patent/JP6650011B2/ja active Active
-
2019
- 2019-12-13 AR ARP190103670A patent/AR117697A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA3112061A1 (en) | 2014-05-22 |
| JP6650011B2 (ja) | 2020-02-19 |
| CA2891279A1 (en) | 2014-05-22 |
| US20150337258A1 (en) | 2015-11-26 |
| BR112015010948A2 (pt) | 2017-07-11 |
| KR102170858B1 (ko) | 2020-10-28 |
| SG10201811616SA (en) | 2019-02-27 |
| BR122020000038B1 (pt) | 2021-11-03 |
| MX358095B (es) | 2018-08-06 |
| JP2019030334A (ja) | 2019-02-28 |
| CA3112061C (en) | 2022-08-09 |
| SG11201503579RA (en) | 2015-06-29 |
| MX2015006099A (es) | 2015-08-06 |
| EP3401319A1 (en) | 2018-11-14 |
| EP3401319B1 (en) | 2020-07-22 |
| US10619131B2 (en) | 2020-04-14 |
| KR20150085834A (ko) | 2015-07-24 |
| CN104812891B (zh) | 2018-10-12 |
| US20180230422A1 (en) | 2018-08-16 |
| JP6433429B2 (ja) | 2018-12-05 |
| CA2891279C (en) | 2022-01-25 |
| BR112015010948B1 (pt) | 2021-10-26 |
| DK2920296T3 (en) | 2018-10-22 |
| EP2920296B1 (en) | 2018-07-18 |
| US10030225B2 (en) | 2018-07-24 |
| CN104812891A (zh) | 2015-07-29 |
| ES2827701T3 (es) | 2021-05-24 |
| JP2015535423A (ja) | 2015-12-14 |
| AR093460A1 (es) | 2015-06-10 |
| WO2014075807A1 (en) | 2014-05-22 |
| DK3401319T3 (da) | 2020-09-07 |
| EP2920296A1 (en) | 2015-09-23 |
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