BR0112361A - Métodos para tratamento de condições oculares mediadas por inflamação - Google Patents

Métodos para tratamento de condições oculares mediadas por inflamação

Info

Publication number
BR0112361A
BR0112361A BR0112361A BR0112361A BR0112361A BR 0112361 A BR0112361 A BR 0112361A BR 0112361 A BR0112361 A BR 0112361A BR 0112361 A BR0112361 A BR 0112361A BR 0112361 A BR0112361 A BR 0112361A
Authority
BR
Brazil
Prior art keywords
methods
eye conditions
treating inflammation
eye
mediated eye
Prior art date
Application number
BR0112361A
Other languages
English (en)
Inventor
Vernon G Wong
Mae W L Hu
Original Assignee
Oculex Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oculex Pharm Inc filed Critical Oculex Pharm Inc
Publication of BR0112361A publication Critical patent/BR0112361A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

"MéTODOS PARA TRATAMENTO DE CONDIçõES OCULARES MEDIADAS POR INFLAMAçãO". São descritos métodos para tratamento de condições oculares mediadas por inflamação, compreendendo: implantar no vítreo do olho de um indivíduo um implante biocorrosível compreendendo um agente antiinflamatório esteróide e um polímero biocorrosível, onde o implante distribui o agente para o vítreo em uma quantidade suficiente para obter uma concentração equivalente a pelo menos cerca de 0,05 <109>g/ml de dexametasona em cerca de 48 horas e mantém uma concentração equivalente a pelo menos cerca de 0,03 <109>g/ml de dexametasona por pelo menos cerca de três semanas.
BR0112361A 2000-07-05 2001-07-03 Métodos para tratamento de condições oculares mediadas por inflamação BR0112361A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21623600P 2000-07-05 2000-07-05
US09/693,008 US6726918B1 (en) 2000-07-05 2000-10-20 Methods for treating inflammation-mediated conditions of the eye
PCT/US2001/021173 WO2002002076A2 (en) 2000-07-05 2001-07-03 Methods for treating inflammation-mediated conditions of the eye

Publications (1)

Publication Number Publication Date
BR0112361A true BR0112361A (pt) 2003-05-20

Family

ID=26910814

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0112361A BR0112361A (pt) 2000-07-05 2001-07-03 Métodos para tratamento de condições oculares mediadas por inflamação

Country Status (13)

Country Link
US (8) US6726918B1 (pt)
EP (1) EP1296645B1 (pt)
JP (1) JP3628679B2 (pt)
AR (1) AR029567A1 (pt)
AT (1) ATE339185T1 (pt)
AU (2) AU7316601A (pt)
BR (1) BR0112361A (pt)
CA (1) CA2414680C (pt)
DE (1) DE60123055T2 (pt)
DK (2) DK1296645T3 (pt)
ES (3) ES2271049T3 (pt)
PT (2) PT3167872T (pt)
WO (1) WO2002002076A2 (pt)

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US8063031B2 (en) 2011-11-22
DK1296645T3 (da) 2007-01-15
US20120035146A1 (en) 2012-02-09
DE60123055D1 (de) 2006-10-26
US8242099B2 (en) 2012-08-14
US9775849B2 (en) 2017-10-03
ES2856846T3 (es) 2021-09-28
US20180021352A1 (en) 2018-01-25
US10206934B2 (en) 2019-02-19
US20120252771A1 (en) 2012-10-04
US6726918B1 (en) 2004-04-27
PT1296645E (pt) 2006-12-29
JP3628679B2 (ja) 2005-03-16
AU7316601A (en) 2002-01-14
EP1296645A2 (en) 2003-04-02
EP1296645B1 (en) 2006-09-13
WO2002002076A2 (en) 2002-01-10
US20040057979A1 (en) 2004-03-25
US20100099655A1 (en) 2010-04-22
DE60123055T2 (de) 2007-02-22
JP2004501954A (ja) 2004-01-22
CA2414680C (en) 2007-09-18
PT3167872T (pt) 2021-01-20
ES2271049T3 (es) 2007-04-16
US20150224119A1 (en) 2015-08-13
CA2414680A1 (en) 2002-01-10
US20130281417A1 (en) 2013-10-24
WO2002002076A3 (en) 2002-07-04
ES2618379T3 (es) 2017-06-21
AU2001273166B2 (en) 2005-10-27
DK3167872T3 (da) 2021-01-18
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AR029567A1 (es) 2003-07-02
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