DK0703786T3 - Anvendelse af nona- og dekapeptider til fremstilling af et lægemiddel til behandling af AIDS - Google Patents

Anvendelse af nona- og dekapeptider til fremstilling af et lægemiddel til behandling af AIDS

Info

Publication number
DK0703786T3
DK0703786T3 DK94913518T DK94913518T DK0703786T3 DK 0703786 T3 DK0703786 T3 DK 0703786T3 DK 94913518 T DK94913518 T DK 94913518T DK 94913518 T DK94913518 T DK 94913518T DK 0703786 T3 DK0703786 T3 DK 0703786T3
Authority
DK
Denmark
Prior art keywords
decapeptides
nona
aids
treatment
pct
Prior art date
Application number
DK94913518T
Other languages
English (en)
Inventor
Juergen Engel
Bernhard Kutscher
Michael Bernd
Ulf Niemeyer
Original Assignee
Zentaris Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Ag filed Critical Zentaris Ag
Application granted granted Critical
Publication of DK0703786T3 publication Critical patent/DK0703786T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A61K38/105—Bombesin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides
DK94913518T 1993-06-18 1994-04-02 Anvendelse af nona- og dekapeptider til fremstilling af et lægemiddel til behandling af AIDS DK0703786T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4320201A DE4320201A1 (de) 1993-06-18 1993-06-18 Verwendung von Cetrorelix und weiteren Nona- und Dekapeptiden zur Herstellung eines Arzneimittels zur Bekämpfung von Aids und zur Wachstumsstimulation
PCT/EP1994/001037 WO1995000168A1 (de) 1993-06-18 1994-04-02 Verwendung von nona- und dekapeptiden zur herstellung eines arzneimittels zur bekämpfung von aids

Publications (1)

Publication Number Publication Date
DK0703786T3 true DK0703786T3 (da) 2002-05-27

Family

ID=6490614

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94913518T DK0703786T3 (da) 1993-06-18 1994-04-02 Anvendelse af nona- og dekapeptider til fremstilling af et lægemiddel til behandling af AIDS

Country Status (24)

Country Link
US (1) US5985834A (da)
EP (1) EP0703786B1 (da)
JP (1) JPH08511784A (da)
KR (1) KR100352541B1 (da)
CN (1) CN1136915C (da)
AT (1) ATE213164T1 (da)
AU (1) AU688315B2 (da)
BR (1) BR9406893A (da)
CZ (1) CZ285997B6 (da)
DE (2) DE4320201A1 (da)
DK (1) DK0703786T3 (da)
ES (1) ES2172533T3 (da)
FI (1) FI113008B (da)
HU (1) HUT73673A (da)
IL (1) IL110045A (da)
NO (1) NO320945B1 (da)
PL (1) PL175580B1 (da)
PT (1) PT703786E (da)
RU (1) RU2154492C2 (da)
SG (1) SG52240A1 (da)
TW (1) TW370532B (da)
UA (1) UA41938C2 (da)
WO (1) WO1995000168A1 (da)
ZA (1) ZA944347B (da)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
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US5843901A (en) * 1995-06-07 1998-12-01 Advanced Research & Technology Institute LHRH antagonist peptides
US5932547A (en) 1996-07-03 1999-08-03 Alza Corporation Non-aqueous polar aprotic peptide formulations
US5916582A (en) * 1996-07-03 1999-06-29 Alza Corporation Aqueous formulations of peptides
US5981489A (en) * 1996-07-18 1999-11-09 Alza Corporation Non-aqueous protic peptide formulations
DE19728737C1 (de) * 1997-07-04 1999-02-11 Johannes Christian Groeninghen Verfahren zur Erkennung und Bestimmung von GnRH-Rezeptoren und die Verwendung von GnRH-Agonisten und GnRH-Antagonisten zur Behandlung eines Tumors ausgehend vom Hirn und/oder Nervensystem und/oder den Hirnhäuten
US8962558B2 (en) 1997-07-04 2015-02-24 Johannes C. van Groeninghen Methods for reducing GnRH-positive tumor cell proliferation using the GnRH antagonist IN3
MXPA02008870A (es) * 2000-03-14 2003-06-24 Zentaris Ag Novedosos antagonistas de lhrh, produccion de los mismos y sus uso como medicamentos.
DE10137174A1 (de) * 2001-07-31 2003-02-13 Zentaris Ag Verwendung von LHRH-Antagonisten in nichtkastrierenden Dosen zur Verbesserung der T-Zellen-vermittelten Immunität
US20040138138A1 (en) * 2001-08-02 2004-07-15 Jurgen Engel Use of LHRH-antagonists in doses that do not cause castration for the improvement of T-cell mediated immunity
IL147138A0 (en) * 2001-12-17 2002-08-14 Yeda Res & Dev Methods of and pharmaceutical compositions for modulating cell adhesion, migration and extravasation
GB0130219D0 (en) * 2001-12-18 2002-02-06 Pfizer Ltd Compounds for the treatment of sexual dysfunction
US7250514B1 (en) * 2002-10-21 2007-07-31 Takeda San Diego, Inc. Histone deacetylase inhibitors
CA2726247C (en) * 2008-05-29 2018-06-26 Isr Immune System Regulation Ab Method and means for treating viral disease, in particular hiv/aids
EP2682460B1 (en) 2008-07-07 2017-04-26 Oxford Nanopore Technologies Limited Enzyme-pore constructs
AU2009269792A1 (en) 2008-07-07 2010-01-14 Oxford Nanopore Technologies Limited Base-detecting pore
GB0820927D0 (en) 2008-11-14 2008-12-24 Isis Innovation Method
JP5843614B2 (ja) 2009-01-30 2016-01-13 オックスフォード ナノポア テクノロジーズ リミテッド 膜貫通配列決定における核酸構築物のためのアダプター
JP2012516145A (ja) * 2009-01-30 2012-07-19 オックスフォード ナノポア テクノロジーズ リミテッド ハイブリダイゼーションリンカー
GB0905140D0 (en) 2009-03-25 2009-05-06 Isis Innovation Method
BR112013020411B1 (pt) 2011-02-11 2021-09-08 Oxford Nanopore Technologies Limited Monômero de msp mutante, construto, polinucleotídeo, poro, kit e aparelho para caracterizar uma sequência de ácido nucleico alvo, e, método para caracterizar uma sequência de ácido nucleico alvo
JP6298404B2 (ja) 2011-07-25 2018-03-20 オックスフォード ナノポール テクノロジーズ リミテッド 膜貫通ポアを用いる二重鎖ポリヌクレオチド配列決定のためのヘアピンループ方法
BR112014025157B1 (pt) 2012-04-10 2022-02-08 Oxford Nanopore Technologies Limited Monômero de lisenina mutante, construto, poro, método para caracterizar um analito alvo, uso de um poro, e, kit
US11155860B2 (en) 2012-07-19 2021-10-26 Oxford Nanopore Technologies Ltd. SSB method
BR112015021788B1 (pt) 2013-03-08 2023-02-28 Oxford Nanopore Technologies Plc Métodos para mover uma ou mais helicases imobilizadas, para controlar o movimento de um polinucleotídeo alvo, para caracterizar um polinucleotídeo alvo e para controlar o carregamento de uma ou mais helicases em um polinucleotídeo alvo, uso de um poro de transmembrana e de um potencial aplicado e de um ou mais espaçadores, complexo, e, kit
GB201314695D0 (en) 2013-08-16 2013-10-02 Oxford Nanopore Tech Ltd Method
GB201313477D0 (en) 2013-07-29 2013-09-11 Univ Leuven Kath Nanopore biosensors for detection of proteins and nucleic acids
GB201403096D0 (en) 2014-02-21 2014-04-09 Oxford Nanopore Tech Ltd Sample preparation method
US10167503B2 (en) 2014-05-02 2019-01-01 Oxford Nanopore Technologies Ltd. Mutant pores
CN117164684A (zh) 2014-09-01 2023-12-05 弗拉芒区生物技术研究所 突变csgg孔
EP3204511B1 (en) 2014-10-07 2021-07-28 Oxford Nanopore Technologies Limited Mutant pores
GB201418159D0 (en) 2014-10-14 2014-11-26 Oxford Nanopore Tech Ltd Method
CN105837674A (zh) * 2016-03-08 2016-08-10 无限极（中国）有限公司 一种东方铃蟾多肽及其制备方法与应用
GB201609220D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
GB201807793D0 (en) 2018-05-14 2018-06-27 Oxford Nanopore Tech Ltd Method

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4677193A (en) * 1985-02-22 1987-06-30 The Salk Institute For Biological Studies Peptides containing an aliphatic-aromatic ketone side chain
US5073624A (en) * 1985-04-09 1991-12-17 Administrators Of The Tulane Educational Fund Therapeutic decapeptides
US4800191A (en) * 1987-07-17 1989-01-24 Schally Andrew Victor LHRH antagonists
AU618029B2 (en) * 1987-11-02 1991-12-12 Imperial Chemical Industries Plc Polypeptide compounds
WO1989009229A1 (en) * 1988-03-31 1989-10-05 Immunobiology Research Institute, Inc. Treatment of hiv viremic patients with thymopentin
HU208439B (en) * 1988-10-14 1993-10-28 Univ Tulane Process for producing pharmaceutical peptides
US5244883A (en) * 1990-11-29 1993-09-14 The Administrators Of The Tulane Educational Fund Nonapeptide bombesin antagonists
CH683149A5 (fr) * 1991-07-22 1994-01-31 Debio Rech Pharma Sa Procédé pour la préparation de microsphères en matériau polymère biodégradable.

Also Published As

Publication number Publication date
UA41938C2 (uk) 2001-10-15
WO1995000168A1 (de) 1995-01-05
EP0703786A1 (de) 1996-04-03
HUT73673A (en) 1996-09-30
PL175580B1 (pl) 1999-01-29
ATE213164T1 (de) 2002-02-15
ES2172533T3 (es) 2002-10-01
FI956014A0 (fi) 1995-12-14
KR100352541B1 (ko) 2002-12-26
PT703786E (pt) 2002-07-31
FI113008B (fi) 2004-02-27
DE4320201A1 (de) 1995-01-12
ZA944347B (en) 1995-02-15
US5985834A (en) 1999-11-16
IL110045A (en) 2000-06-01
CZ285997B6 (cs) 1999-12-15
AU6564794A (en) 1995-01-17
JPH08511784A (ja) 1996-12-10
RU2154492C2 (ru) 2000-08-20
FI956014A (fi) 1995-12-14
CN1125400A (zh) 1996-06-26
CZ308995A3 (en) 1996-03-13
NO320945B1 (no) 2006-02-20
NO954996L (no) 1995-12-08
TW370532B (en) 1999-09-21
IL110045A0 (en) 1994-10-07
NO954996D0 (no) 1995-12-08
EP0703786B1 (de) 2002-02-13
SG52240A1 (en) 1998-09-28
DE59410052D1 (de) 2002-03-21
HU9503605D0 (en) 1996-02-28
KR960703015A (ko) 1996-06-19
PL312219A1 (en) 1996-04-01
BR9406893A (pt) 1996-09-10
CN1136915C (zh) 2004-02-04
AU688315B2 (en) 1998-03-12

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