MXPA02008870A - Novedosos antagonistas de lhrh, produccion de los mismos y sus uso como medicamentos. - Google Patents
Novedosos antagonistas de lhrh, produccion de los mismos y sus uso como medicamentos.Info
- Publication number
- MXPA02008870A MXPA02008870A MXPA02008870A MXPA02008870A MXPA02008870A MX PA02008870 A MXPA02008870 A MX PA02008870A MX PA02008870 A MXPA02008870 A MX PA02008870A MX PA02008870 A MXPA02008870 A MX PA02008870A MX PA02008870 A MXPA02008870 A MX PA02008870A
- Authority
- MX
- Mexico
- Prior art keywords
- medicament
- production
- lhrh antagonists
- peptides
- novel lhrh
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Genetics & Genomics (AREA)
- Reproductive Health (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La invencion se refiere a péptidos que comprenden un componente aminoácido N-metilado y cuya solubilidad en agua es mejor. Los medicamentos que contienen los peptidos de conformidad con la invencion se pueden usar para el tratamiento de tumores dependientes de las hormonas y de las enfermedades no malignas en que influyen las hormonas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/525,007 US6627609B1 (en) | 1999-03-17 | 2000-03-14 | LHRH antagonists having improved solubility properties |
PCT/EP2001/002719 WO2001068676A2 (de) | 2000-03-14 | 2001-03-12 | Lh-rh-antagonisten, deren herstellung und verwendung als arzeimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA02008870A true MXPA02008870A (es) | 2003-06-24 |
Family
ID=24091545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA02008870A MXPA02008870A (es) | 2000-03-14 | 2001-03-12 | Novedosos antagonistas de lhrh, produccion de los mismos y sus uso como medicamentos. |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP1268522B1 (es) |
JP (1) | JP3805679B2 (es) |
KR (1) | KR100607396B1 (es) |
CN (2) | CN100500692C (es) |
AT (1) | ATE408619T1 (es) |
AU (2) | AU2001260110B2 (es) |
BG (1) | BG107121A (es) |
BR (1) | BR0109279A (es) |
CA (1) | CA2402193C (es) |
DE (1) | DE50114335D1 (es) |
DK (1) | DK1268522T3 (es) |
ES (1) | ES2312435T3 (es) |
HR (1) | HRP20020810A2 (es) |
HU (1) | HUP0300222A3 (es) |
IL (1) | IL151647A0 (es) |
MX (1) | MXPA02008870A (es) |
NO (1) | NO20024363L (es) |
NZ (1) | NZ521273A (es) |
PL (1) | PL357999A1 (es) |
PT (1) | PT1268522E (es) |
RU (1) | RU2248982C9 (es) |
SK (1) | SK14332002A3 (es) |
UA (1) | UA79070C2 (es) |
WO (1) | WO2001068676A2 (es) |
ZA (1) | ZA200207248B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100340572C (zh) * | 2004-12-01 | 2007-10-03 | 中国人民解放军军事医学科学院毒物药物研究所 | 新的lhrh拮抗剂 |
CN101037472B (zh) * | 2006-03-14 | 2013-03-27 | 中国人民解放军军事医学科学院毒物药物研究所 | 具有低组胺释放作用的促黄体生成素释放激素拮抗剂 |
KR101863136B1 (ko) | 2008-01-24 | 2018-05-31 | 에스퍼란스 파마슈티컬스, 인코포레이티드 | 용해 도메인 융합 구성물 및 이를 제조하고 사용하는 방법 |
CN101597321B (zh) * | 2008-06-03 | 2013-04-24 | 中国人民解放军军事医学科学院毒物药物研究所 | 长效低组胺释放副作用的lhrh拮抗剂 |
WO2010142060A1 (zh) * | 2009-06-11 | 2010-12-16 | 中国人民解放军军事医学科学院毒物药物研究所 | 长效低组胺释放副作用的lhrh拮抗剂 |
AU2013337926B2 (en) | 2012-10-30 | 2017-12-21 | Esperance Pharmaceuticals, Inc. | Antibody/drug conjugates and methods of use |
CN104418936B (zh) * | 2013-08-20 | 2018-06-05 | 中国人民解放军军事医学科学院毒物药物研究所 | Lhrh拮抗剂衍生物及其药物用途 |
FR3024612B1 (fr) * | 2014-08-04 | 2018-03-09 | Alstom Transp Tech | Module d'alimentation electrique d'un bloc moteur, systeme de traction et vehicule electrique associe |
RU2585367C1 (ru) * | 2014-11-05 | 2016-05-27 | Наталья Владимировна Спиридонова | Способ лечения бесплодия у женщин с миомой матки |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5300492A (en) | 1988-02-10 | 1994-04-05 | Tap Pharmaceuticals | LHRH analogs |
US5140009A (en) | 1988-02-10 | 1992-08-18 | Tap Pharmaceuticals, Inc. | Octapeptide LHRH antagonists |
US5110904A (en) * | 1989-08-07 | 1992-05-05 | Abbott Laboratories | Lhrh analogs |
IL101074A (en) | 1991-03-14 | 1997-09-30 | Salk Inst For Biological Studi | GnRH ANALOGS AND THEIR PREPARATION |
DK0593491T3 (da) | 1991-04-25 | 1997-03-17 | Romano Deghenghi | Luteiniseringshormonfrigørende hormonantagonistpeptider |
EP0673254A4 (en) | 1992-12-04 | 1998-11-18 | Abbott Lab | HORMONE ANTAGONISTS RELEASING LUTEINIZING HORMONE (LHRH) OF MODIFIED DECAPEPTIDES IN POSITION 6. |
CA2136079A1 (en) | 1992-12-18 | 1994-07-07 | Fortuna Haviv | Lhrh antagonists having modified aminoacyl residues at positions 5 and 6 |
IL108509A0 (en) | 1993-02-22 | 1994-05-30 | Salk Inst For Biological Studi | GnRH antagonist peptides |
DE4320201A1 (de) * | 1993-06-18 | 1995-01-12 | Asta Medica Ag | Verwendung von Cetrorelix und weiteren Nona- und Dekapeptiden zur Herstellung eines Arzneimittels zur Bekämpfung von Aids und zur Wachstumsstimulation |
DE19544212A1 (de) * | 1995-11-28 | 1997-06-05 | Asta Medica Ag | Neue LH-RH-Antagonisten mit verbesserter Wirkung |
DE19911771B4 (de) | 1999-03-17 | 2006-03-30 | Zentaris Gmbh | LHRH-Antagonist, Verfahren zu seiner Herstellung und seiner Verwendung |
-
2001
- 2001-03-12 KR KR1020027012059A patent/KR100607396B1/ko active IP Right Grant
- 2001-03-12 NZ NZ521273A patent/NZ521273A/en unknown
- 2001-03-12 AT AT01933682T patent/ATE408619T1/de not_active IP Right Cessation
- 2001-03-12 MX MXPA02008870A patent/MXPA02008870A/es active IP Right Grant
- 2001-03-12 JP JP2001567766A patent/JP3805679B2/ja not_active Expired - Lifetime
- 2001-03-12 DE DE50114335T patent/DE50114335D1/de not_active Expired - Fee Related
- 2001-03-12 DK DK01933682T patent/DK1268522T3/da active
- 2001-03-12 IL IL15164701A patent/IL151647A0/xx unknown
- 2001-03-12 BR BR0109279-0A patent/BR0109279A/pt not_active IP Right Cessation
- 2001-03-12 CN CNB2006100817821A patent/CN100500692C/zh not_active Expired - Fee Related
- 2001-03-12 EP EP01933682A patent/EP1268522B1/de not_active Expired - Lifetime
- 2001-03-12 AU AU2001260110A patent/AU2001260110B2/en not_active Ceased
- 2001-03-12 CN CN01807543A patent/CN1443195A/zh active Pending
- 2001-03-12 RU RU2002127786/04A patent/RU2248982C9/ru active
- 2001-03-12 PT PT01933682T patent/PT1268522E/pt unknown
- 2001-03-12 WO PCT/EP2001/002719 patent/WO2001068676A2/de active IP Right Grant
- 2001-03-12 SK SK1433-2002A patent/SK14332002A3/sk not_active Application Discontinuation
- 2001-03-12 ES ES01933682T patent/ES2312435T3/es not_active Expired - Lifetime
- 2001-03-12 HU HU0300222A patent/HUP0300222A3/hu unknown
- 2001-03-12 CA CA2402193A patent/CA2402193C/en not_active Expired - Lifetime
- 2001-03-12 PL PL01357999A patent/PL357999A1/xx unknown
- 2001-03-12 AU AU6011001A patent/AU6011001A/xx active Pending
- 2001-12-03 UA UA2002108075A patent/UA79070C2/uk unknown
-
2002
- 2002-09-10 ZA ZA200207248A patent/ZA200207248B/en unknown
- 2002-09-12 NO NO20024363A patent/NO20024363L/no not_active Application Discontinuation
- 2002-09-18 BG BG107121A patent/BG107121A/bg unknown
- 2002-10-10 HR HRP20020810 patent/HRP20020810A2/hr not_active Application Discontinuation
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Legal Events
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HC | Change of company name or juridical status | ||
FG | Grant or registration |