ATE413179T1 - Therapeutische verwendungen von steroiden bei blutzellmangelzustaenden - Google Patents
Therapeutische verwendungen von steroiden bei blutzellmangelzustaendenInfo
- Publication number
- ATE413179T1 ATE413179T1 AT00970511T AT00970511T ATE413179T1 AT E413179 T1 ATE413179 T1 AT E413179T1 AT 00970511 T AT00970511 T AT 00970511T AT 00970511 T AT00970511 T AT 00970511T AT E413179 T1 ATE413179 T1 AT E413179T1
- Authority
- AT
- Austria
- Prior art keywords
- steroids
- blood cell
- therapeutic uses
- cell deficiency
- deficiency conditions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0025—Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J17/005—Glycosides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
- C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
- C07J73/003—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by oxygen as hetero atom
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16145399P | 1999-10-25 | 1999-10-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE413179T1 true ATE413179T1 (de) | 2008-11-15 |
Family
ID=22581233
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00970511T ATE413179T1 (de) | 1999-10-25 | 2000-09-28 | Therapeutische verwendungen von steroiden bei blutzellmangelzustaenden |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1223941B1 (de) |
JP (1) | JP2003512474A (de) |
AT (1) | ATE413179T1 (de) |
AU (3) | AU782736B2 (de) |
CA (1) | CA2388939C (de) |
DE (1) | DE60040753D1 (de) |
WO (1) | WO2001030802A2 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060079492A1 (en) | 1999-10-25 | 2006-04-13 | Ahlem Clarence N | Compositions and treatment methods |
US20070129282A1 (en) | 1998-11-24 | 2007-06-07 | Ahlem Clarence N | Pharmaceutical treatments and compositions |
US6667299B1 (en) | 2000-03-16 | 2003-12-23 | Hollis-Eden Pharmaceuticals, Inc. | Pharmaceutical compositions and treatment methods |
DK1955700T3 (da) | 1999-09-30 | 2011-05-23 | Harbor Biosciences Inc | Terapeutisk behandling af androgenreceptor-betingede lidelser |
EP2135611A1 (de) * | 2001-03-01 | 2009-12-23 | Hollis-Eden Pharmaceuticals Inc. | Pregn-5-en-20-yn-3,7,17-triol Derivate zur therapeutischen Verwendung |
US20050101581A1 (en) | 2002-08-28 | 2005-05-12 | Reading Christopher L. | Therapeutic treatment methods 2 |
AU2003278744B2 (en) * | 2002-08-28 | 2010-07-29 | Harbor Biosciences, Inc. | Therapeutic treatment methods |
US8569275B2 (en) | 2002-08-28 | 2013-10-29 | Harbor Therapeutics, Inc. | Steroids having 7-oxgen and 17-heteroaryl substitution |
US20040242618A1 (en) | 2003-04-01 | 2004-12-02 | Lardy Henry A. | Antiandrogens with marginal agonist activity and methods of use |
US7910755B2 (en) | 2004-09-29 | 2011-03-22 | Harbor Biosciences, Inc. | Stem cell expansion and uses |
US20070014719A1 (en) * | 2004-09-29 | 2007-01-18 | Reading Christopher L | Steroid analogs and characterization and treatment methods |
JP4839021B2 (ja) * | 2005-06-10 | 2011-12-14 | 国立大学法人 岡山大学 | 白血球及び/又は造血幹・前駆細胞動員剤 |
US8486926B2 (en) | 2006-11-17 | 2013-07-16 | Harbor Therapeutics, Inc. | Steroid tetrol solid state forms |
US8354396B2 (en) | 2006-11-17 | 2013-01-15 | Harbor Therapeutics, Inc. | Drug identification and treatment method |
US8217025B2 (en) | 2006-11-17 | 2012-07-10 | Harbor Therapeutics, Inc. | Drug screening and treatment methods |
JP2011527986A (ja) | 2008-04-03 | 2011-11-10 | ハーバー バイオサイエンシーズ,インコーポレイテッド | 医薬の固体状態形態 |
US8309746B2 (en) | 2008-06-06 | 2012-11-13 | Harbor Therapeutics, Inc | Methods for preparing 17-alkynyl-7-hydroxy steroids and related compounds |
WO2010024930A2 (en) | 2008-08-28 | 2010-03-04 | President And Fellows Of Harvard College | Cortistatin analogues and syntheses therof |
KR102100307B1 (ko) * | 2012-03-21 | 2020-04-14 | 다나-파버 캔서 인스티튜트 인크. | 인간 림프 기관-유래 억제성 기질 세포의 분리 및 용도 |
EA201891279A1 (ru) | 2013-12-24 | 2019-01-31 | Президент Энд Феллоус Оф Гарвард Колледж | Аналоги кортистатина, их синтез и применения |
EP3294298A4 (de) | 2015-05-08 | 2018-10-17 | President and Fellows of Harvard College | Cortistatin-analoga, synthese und verwendungen |
EP3316889A4 (de) | 2015-07-01 | 2018-11-14 | President and Fellows of Harvard College | Cortistatin-analoga sowie synthese und verwendungen davon |
US10836788B2 (en) | 2019-02-05 | 2020-11-17 | SD Chem, Inc. | Aqueous suspension compositions, formulations, and water dispersible dry compositions comprising 16alpha-bromo-3beta-hydroxy-5alpha-androstan-17-ketone and hydrates, derivatives, and analogs thereof |
US10857163B1 (en) | 2019-09-30 | 2020-12-08 | Athenen Therapeutics, Inc. | Compositions that preferentially potentiate subtypes of GABAA receptors and methods of use thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL99772C (de) * | ||||
US4602008A (en) * | 1984-12-14 | 1986-07-22 | Progenics, Inc. | Alkylated etiocholanolones and use as an anti-diabetic, anti-obesity and erythropoietic agent |
FR2696934B1 (fr) * | 1992-10-20 | 1995-06-02 | Conservatoire Nal Arts Metiers | Dérivés de stéroïdes naturels 3B hydroxyles ayant des propriétés de déclenchement et de stimulation de l'immunité, composition les contenant et procédé pour les obtenir. |
EP0801557B1 (de) * | 1995-10-12 | 2003-07-02 | Supergen, Inc. | Liposomformulierung von 5-beta steroiden |
AU718232B2 (en) * | 1995-11-13 | 2000-04-13 | Supergen, Inc. | Improved formulation for administration of steroid compounds |
GB9708716D0 (en) * | 1997-04-29 | 1997-06-18 | Imperial College | Chronic heart failure |
WO1999044616A1 (en) * | 1998-03-06 | 1999-09-10 | Brigham Young University | Steroid derived antibiotics |
-
2000
- 2000-09-28 EP EP00970511A patent/EP1223941B1/de not_active Expired - Lifetime
- 2000-09-28 AT AT00970511T patent/ATE413179T1/de not_active IP Right Cessation
- 2000-09-28 JP JP2001533153A patent/JP2003512474A/ja active Pending
- 2000-09-28 CA CA002388939A patent/CA2388939C/en not_active Expired - Fee Related
- 2000-09-28 DE DE60040753T patent/DE60040753D1/de not_active Expired - Lifetime
- 2000-09-28 WO PCT/US2000/026771 patent/WO2001030802A2/en active IP Right Grant
- 2000-09-28 AU AU79880/00A patent/AU782736B2/en not_active Ceased
-
2005
- 2005-11-23 AU AU2005237117A patent/AU2005237117B2/en not_active Ceased
-
2008
- 2008-12-04 AU AU2008255138A patent/AU2008255138B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
AU2005237117B2 (en) | 2008-09-04 |
CA2388939A1 (en) | 2001-05-03 |
WO2001030802A2 (en) | 2001-05-03 |
EP1223941A2 (de) | 2002-07-24 |
AU2005237117A1 (en) | 2005-12-15 |
AU782736B2 (en) | 2005-08-25 |
DE60040753D1 (de) | 2008-12-18 |
AU2008255138A1 (en) | 2009-01-08 |
AU2008255138A8 (en) | 2011-10-20 |
AU2008255138A2 (en) | 2009-01-15 |
AU7988000A (en) | 2001-05-08 |
WO2001030802A3 (en) | 2002-02-14 |
AU2008255138B2 (en) | 2011-02-24 |
CA2388939C (en) | 2009-06-09 |
EP1223941B1 (de) | 2008-11-05 |
JP2003512474A (ja) | 2003-04-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |