BG64560B1 - Бензазепинови производни, лекарствени средства, които ги съдържат, и тяхното приложение за получаването на лекарства - Google Patents

Бензазепинови производни, лекарствени средства, които ги съдържат, и тяхното приложение за получаването на лекарства Download PDF

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Publication number
BG64560B1
BG64560B1 BG102836A BG10283698A BG64560B1 BG 64560 B1 BG64560 B1 BG 64560B1 BG 102836 A BG102836 A BG 102836A BG 10283698 A BG10283698 A BG 10283698A BG 64560 B1 BG64560 B1 BG 64560B1
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BG
Bulgaria
Prior art keywords
alkyl
group
hydrogen
substituted
dream
Prior art date
Application number
BG102836A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG102836A (en
Inventor
Laszlo Czollner
Johannes Froehlich
Ulrich Jordis
Kuenburg Bernhard
Original Assignee
Sanochemia Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanochemia Ltd. filed Critical Sanochemia Ltd.
Publication of BG102836A publication Critical patent/BG102836A/xx
Publication of BG64560B1 publication Critical patent/BG64560B1/bg

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG102836A 1996-04-19 1998-10-12 Бензазепинови производни, лекарствени средства, които ги съдържат, и тяхното приложение за получаването на лекарства BG64560B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0071696A AT403803B (de) 1996-04-19 1996-04-19 Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln

Publications (2)

Publication Number Publication Date
BG102836A BG102836A (en) 1999-09-30
BG64560B1 true BG64560B1 (bg) 2005-07-29

Family

ID=3497932

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102836A BG64560B1 (bg) 1996-04-19 1998-10-12 Бензазепинови производни, лекарствени средства, които ги съдържат, и тяхното приложение за получаването на лекарства

Country Status (12)

Country Link
US (2) US6638925B2 (fr)
EP (2) EP1757608A1 (fr)
AT (1) AT403803B (fr)
AU (1) AU2498597A (fr)
BG (1) BG64560B1 (fr)
CZ (1) CZ300211B6 (fr)
IS (1) IS4839A (fr)
NO (1) NO324211B1 (fr)
PL (2) PL189834B1 (fr)
RO (1) RO120136B1 (fr)
TW (1) TWI224595B (fr)
WO (1) WO1997040049A1 (fr)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
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US7214686B2 (en) * 1997-06-30 2007-05-08 Targacept, Inc. Pharmaceutical compositions and methods for effecting dopamine release
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US7459469B2 (en) * 2004-11-10 2008-12-02 Targacept, Inc. Hydroxybenzoate salts of metanicotine compounds
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CL2007002684A1 (es) * 2006-09-15 2008-06-27 Astrazeneca Ab Targacept Inc Combinacion que comprende un antipsicotico y (2s)-(4e)-n-metil-5-[3-(5-isopropoxipiridin)il]-4-penten-2-amina; composicion farmaceutica que la comprende; kit farmaceutico; y uso para tratar perjuicio cognitivo y/o trastorno psicoticos.
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JP5504253B2 (ja) 2008-04-14 2014-05-28 ニューロダイン ライフ サイエンス インコーポレイテッド ヒトの脳疾患の治療のためのプロドラッグとしてのガランタミン誘導体
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CN103180277A (zh) 2010-05-20 2013-06-26 塔格塞普特股份有限公司 制备芳基取代的烯属胺的新方法
WO2013160728A1 (fr) 2012-04-26 2013-10-31 Alma Mater Studiorum - Universita' Di Bologna Composés à double ciblage pour le traitement de la maladie d'alzheimer
CN104447767B (zh) * 2013-09-24 2018-08-03 连云港金康医药科技有限公司 氮杂双环[3,2,1]辛烷衍生物及其应用
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Citations (2)

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Publication number Priority date Publication date Assignee Title
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WO2000032199A1 (fr) 1998-12-01 2000-06-08 Sanochemia Pharmazeutika Aktiengesellschaft Utilisation de galanthamine et de derives de galanthamine en cas de lesions cerebrales fonctionnelles aigues
AT414125B (de) 2003-09-29 2006-09-15 Sanochemia Pharmazeutika Ag Neue derivate des 4a,5,9,10,11,12-hexahydro- benzofuro(3a,3,2)(2) benzazepin, verfahren zu deren herstellung sowie deren verwendung zur herstellung von arzneimitteln

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Also Published As

Publication number Publication date
US20040067974A1 (en) 2004-04-08
CZ300211B6 (cs) 2009-03-18
PL189834B1 (pl) 2005-09-30
RO120136B1 (ro) 2005-09-30
NO984852D0 (no) 1998-10-16
US20030092700A1 (en) 2003-05-15
US7101890B2 (en) 2006-09-05
NO324211B1 (no) 2007-09-10
EP0897387A1 (fr) 1999-02-24
AT403803B (de) 1998-05-25
BG102836A (en) 1999-09-30
WO1997040049A1 (fr) 1997-10-30
ATA71696A (de) 1997-10-15
NO984852L (no) 1998-11-16
IS4839A (is) 1998-08-28
AU2498597A (en) 1997-11-12
CZ332498A3 (cs) 1999-05-12
PL190032B1 (pl) 2005-10-31
PL329411A1 (en) 1999-03-29
US6638925B2 (en) 2003-10-28
EP1757608A1 (fr) 2007-02-28
TWI224595B (en) 2004-12-01

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