BG106110A - Метод за лечение на рефракторни тумори при човекас рецепторни антагонисти на епидермалния растеженфактор - Google Patents
Метод за лечение на рефракторни тумори при човекас рецепторни антагонисти на епидермалния растеженфактор Download PDFInfo
- Publication number
- BG106110A BG106110A BG106110A BG10611001A BG106110A BG 106110 A BG106110 A BG 106110A BG 106110 A BG106110 A BG 106110A BG 10611001 A BG10611001 A BG 10611001A BG 106110 A BG106110 A BG 106110A
- Authority
- BG
- Bulgaria
- Prior art keywords
- antagonist
- egfr
- radiation
- tumors
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31228499A | 1999-05-14 | 1999-05-14 | |
US37402899A | 1999-08-13 | 1999-08-13 | |
PCT/US2000/011756 WO2000069459A1 (en) | 1999-05-14 | 2000-05-01 | Treatment of refractory human tumors with epidermal growth factor receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
BG106110A true BG106110A (bg) | 2002-04-30 |
Family
ID=26978320
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG106110A BG106110A (bg) | 1999-05-14 | 2001-11-14 | Метод за лечение на рефракторни тумори при човекас рецепторни антагонисти на епидермалния растеженфактор |
Country Status (20)
Country | Link |
---|---|
US (3) | US20020012663A1 (no) |
EP (2) | EP2042194A3 (no) |
JP (2) | JP2003520195A (no) |
KR (1) | KR20020000223A (no) |
CN (1) | CN1200734C (no) |
AU (1) | AU782994C (no) |
BG (1) | BG106110A (no) |
BR (1) | BR0010524A (no) |
CA (1) | CA2373815A1 (no) |
CZ (1) | CZ20014083A3 (no) |
EE (1) | EE200100603A (no) |
HK (1) | HK1047236A1 (no) |
HU (1) | HUP0201480A3 (no) |
IL (1) | IL146480A0 (no) |
MX (1) | MXPA01011632A (no) |
NO (1) | NO20015546L (no) |
PL (1) | PL365999A1 (no) |
RU (1) | RU2294761C2 (no) |
SK (1) | SK16522001A3 (no) |
WO (1) | WO2000069459A1 (no) |
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CA2373815A1 (en) * | 1999-05-14 | 2000-11-23 | Imclone Systems Incorporated | Treatment of refractory human tumors with epidermal growth factor receptor antagonists |
US7740841B1 (en) * | 2000-01-28 | 2010-06-22 | Sunnybrook Health Science Center | Therapeutic method for reducing angiogenesis |
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US20020151508A1 (en) * | 2001-02-09 | 2002-10-17 | Schering Corporation | Methods for treating proliferative diseases |
EP1236474A1 (en) * | 2001-02-26 | 2002-09-04 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Negative regulation of epidermal growth factor receptor activity by Mig-6 |
US20080008704A1 (en) * | 2001-03-16 | 2008-01-10 | Mark Rubin | Methods of treating colorectal cancer with anti-epidermal growth factor antibodies |
US7498029B2 (en) | 2001-05-01 | 2009-03-03 | The General Hospital Corporation | Photoimmunotherapies for cancer using combination therapies |
CN1507355A (zh) * | 2001-05-08 | 2004-06-23 | Ĭ��ר������˾ | 使用抗egfr抗体和抗激素剂的联合疗法 |
PT1392359E (pt) | 2001-05-11 | 2010-01-27 | Ludwig Inst For Cancer Res Ltd | Proteínas de ligação específica e suas utilizações |
US20100056762A1 (en) | 2001-05-11 | 2010-03-04 | Old Lloyd J | Specific binding proteins and uses thereof |
KR100719624B1 (ko) * | 2001-05-18 | 2007-05-21 | 석정철 | 시각장애인을 위한 접착형 점자유도블록 및점자유도블록의 접착방법 |
WO2004058821A2 (en) * | 2002-12-27 | 2004-07-15 | Domantis Limited | Dual specific single domain antibodies specific for a ligand and for the receptor of the ligand |
JP4303105B2 (ja) * | 2001-06-28 | 2009-07-29 | ドマンティス リミテッド | 二重特異性リガンドとその利用 |
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CA2477932A1 (en) * | 2002-03-08 | 2003-09-18 | Axel Ullrich | Use of egfr transactivation inhibitors in human cancer |
US9321832B2 (en) * | 2002-06-28 | 2016-04-26 | Domantis Limited | Ligand |
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US20040147428A1 (en) * | 2002-11-15 | 2004-07-29 | Pluenneke John D. | Methods of treatment using an inhibitor of epidermal growth factor receptor |
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-
2000
- 2000-05-01 CA CA002373815A patent/CA2373815A1/en not_active Abandoned
- 2000-05-01 IL IL14648000A patent/IL146480A0/xx unknown
- 2000-05-01 EP EP08015392A patent/EP2042194A3/en not_active Withdrawn
- 2000-05-01 RU RU2001130771/14A patent/RU2294761C2/ru active
- 2000-05-01 HU HU0201480A patent/HUP0201480A3/hu unknown
- 2000-05-01 EE EEP200100603A patent/EE200100603A/xx unknown
- 2000-05-01 CN CNB008103216A patent/CN1200734C/zh not_active Expired - Fee Related
- 2000-05-01 AU AU46871/00A patent/AU782994C/en not_active Ceased
- 2000-05-01 JP JP2000617919A patent/JP2003520195A/ja active Pending
- 2000-05-01 SK SK1652-2001A patent/SK16522001A3/sk unknown
- 2000-05-01 EP EP00928671A patent/EP1218032A4/en not_active Withdrawn
- 2000-05-01 MX MXPA01011632A patent/MXPA01011632A/es not_active Application Discontinuation
- 2000-05-01 PL PL00365999A patent/PL365999A1/xx not_active IP Right Cessation
- 2000-05-01 CZ CZ20014083A patent/CZ20014083A3/cs unknown
- 2000-05-01 BR BR0010524-4A patent/BR0010524A/pt not_active IP Right Cessation
- 2000-05-01 KR KR1020017014494A patent/KR20020000223A/ko not_active Application Discontinuation
- 2000-05-01 WO PCT/US2000/011756 patent/WO2000069459A1/en active IP Right Grant
-
2001
- 2001-04-24 US US09/840,146 patent/US20020012663A1/en not_active Abandoned
- 2001-11-13 NO NO20015546A patent/NO20015546L/no not_active Application Discontinuation
- 2001-11-14 BG BG106110A patent/BG106110A/bg unknown
- 2001-11-30 US US09/996,954 patent/US20030157104A1/en not_active Abandoned
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2002
- 2002-12-03 HK HK02108768.1A patent/HK1047236A1/zh unknown
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2004
- 2004-12-20 US US11/018,950 patent/US20050112120A1/en not_active Abandoned
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2008
- 2008-09-24 JP JP2008244928A patent/JP2009120583A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP1218032A4 (en) | 2005-05-25 |
AU4687100A (en) | 2000-12-05 |
RU2294761C2 (ru) | 2007-03-10 |
JP2009120583A (ja) | 2009-06-04 |
EE200100603A (et) | 2003-02-17 |
CZ20014083A3 (cs) | 2002-08-14 |
SK16522001A3 (sk) | 2002-10-08 |
HUP0201480A3 (en) | 2009-03-30 |
KR20020000223A (ko) | 2002-01-05 |
EP2042194A2 (en) | 2009-04-01 |
US20020012663A1 (en) | 2002-01-31 |
AU782994B2 (en) | 2005-09-15 |
PL365999A1 (en) | 2005-01-24 |
EP1218032A1 (en) | 2002-07-03 |
AU782994C (en) | 2006-08-24 |
MXPA01011632A (es) | 2002-11-07 |
US20030157104A1 (en) | 2003-08-21 |
WO2000069459A1 (en) | 2000-11-23 |
CN1200734C (zh) | 2005-05-11 |
IL146480A0 (en) | 2002-07-25 |
US20050112120A1 (en) | 2005-05-26 |
BR0010524A (pt) | 2002-05-28 |
CA2373815A1 (en) | 2000-11-23 |
JP2003520195A (ja) | 2003-07-02 |
HUP0201480A2 (en) | 2002-08-28 |
NO20015546L (no) | 2002-01-14 |
HK1047236A1 (zh) | 2003-02-14 |
EP2042194A3 (en) | 2009-04-22 |
NO20015546D0 (no) | 2001-11-13 |
CN1361700A (zh) | 2002-07-31 |
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