BG106003A - Нови n-цианометиламиди и състави като протеазни инхибитори - Google Patents
Нови n-цианометиламиди и състави като протеазни инхибиториInfo
- Publication number
- BG106003A BG106003A BG106003A BG10600301A BG106003A BG 106003 A BG106003 A BG 106003A BG 106003 A BG106003 A BG 106003A BG 10600301 A BG10600301 A BG 10600301A BG 106003 A BG106003 A BG 106003A
- Authority
- BG
- Bulgaria
- Prior art keywords
- cyanomethylamides
- compositions
- new
- protease inhibitors
- inhibitors
- Prior art date
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
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Abstract
Съединенията са цистеинпротеазни инхибитори, по-специално N-цианометиламиди с формула@@в която заместителите имат значенията, посочени в описанието. Изобретението се отнася и до техните фармацевтичноприемливи соли и N-оксиди, до използването им катотерапевтични средства и до методи за тяхното получаване.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12442099P | 1999-03-15 | 1999-03-15 | |
PCT/US2000/006747 WO2000055125A2 (en) | 1999-03-15 | 2000-03-15 | N-cyanomethyl amides as protease inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
BG106003A true BG106003A (bg) | 2002-06-28 |
Family
ID=22414780
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG106003A BG106003A (bg) | 1999-03-15 | 2001-10-10 | Нови n-цианометиламиди и състави като протеазни инхибитори |
BG106013A BG106013A (bg) | 1999-03-15 | 2001-10-12 | Нови съединения и състави като протеазни инхибитори |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG106013A BG106013A (bg) | 1999-03-15 | 2001-10-12 | Нови съединения и състави като протеазни инхибитори |
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US (7) | US6455502B1 (bg) |
EP (2) | EP1161415B1 (bg) |
JP (2) | JP2002539191A (bg) |
KR (2) | KR20010111277A (bg) |
CN (2) | CN1362947A (bg) |
AT (2) | ATE259782T1 (bg) |
AU (2) | AU774827B2 (bg) |
BG (2) | BG106003A (bg) |
BR (2) | BR0009043A (bg) |
CA (2) | CA2368122A1 (bg) |
CZ (2) | CZ20013217A3 (bg) |
DE (2) | DE60008369T2 (bg) |
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ES (2) | ES2245303T3 (bg) |
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HR (2) | HRP20010738B1 (bg) |
HU (2) | HUP0200347A3 (bg) |
IL (3) | IL145429A0 (bg) |
IS (1) | IS6069A (bg) |
NO (2) | NO20014484L (bg) |
NZ (1) | NZ514234A (bg) |
PL (2) | PL350453A1 (bg) |
PT (1) | PT1178958E (bg) |
SK (2) | SK12882001A3 (bg) |
TR (3) | TR200201874T2 (bg) |
TW (1) | TWI290132B (bg) |
UA (1) | UA76088C2 (bg) |
WO (2) | WO2000055126A2 (bg) |
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