BE905890A - Anticorps monoclonaux a reaction croisee et protection croisee vis-a-vis des serotypes de p.aeruginosa. - Google Patents

Anticorps monoclonaux a reaction croisee et protection croisee vis-a-vis des serotypes de p.aeruginosa.

Info

Publication number
BE905890A
BE905890A BE0/217509A BE217509A BE905890A BE 905890 A BE905890 A BE 905890A BE 0/217509 A BE0/217509 A BE 0/217509A BE 217509 A BE217509 A BE 217509A BE 905890 A BE905890 A BE 905890A
Authority
BE
Belgium
Prior art keywords
monoclonal antibodies
cross
protection against
aeruginosa serotypes
reaction
Prior art date
Application number
BE0/217509A
Other languages
English (en)
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of BE905890A publication Critical patent/BE905890A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

On a produit des lignées de cellules secrétant des anticorps monoclonaux humains capables de se lier aux molécules de lipopolysaccharide de sérotypes IATS choisis de Pseudomanas aeruginosa. Sont aussi comprises des compositions pharmaceutiques contenant ces anticorps, en combinaison avec d'autres anticorps monoclonaux, des fractions de plasma sanguin et des agents antimicrobiens, ainsi que l'utilisation prophylactactique et thérapeutique de ces compositions dans le traitement des infections.
BE0/217509A 1985-12-10 1986-12-10 Anticorps monoclonaux a reaction croisee et protection croisee vis-a-vis des serotypes de p.aeruginosa. BE905890A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80739485A 1985-12-10 1985-12-10
US93117986A 1986-11-24 1986-11-24

Publications (1)

Publication Number Publication Date
BE905890A true BE905890A (fr) 1987-06-10

Family

ID=27123006

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/217509A BE905890A (fr) 1985-12-10 1986-12-10 Anticorps monoclonaux a reaction croisee et protection croisee vis-a-vis des serotypes de p.aeruginosa.

Country Status (21)

Country Link
US (4) US5378812A (fr)
JP (1) JPH07116237B2 (fr)
KR (1) KR910008361B1 (fr)
CN (1) CN86108380A (fr)
AT (1) AT400441B (fr)
BE (1) BE905890A (fr)
CH (1) CH677362A5 (fr)
DE (1) DE3642095C2 (fr)
DK (1) DK594586A (fr)
FI (1) FI86377C (fr)
FR (1) FR2593826B1 (fr)
GB (1) GB2185266B (fr)
HU (1) HUT41836A (fr)
IE (1) IE59741B1 (fr)
IT (1) IT1199735B (fr)
LU (1) LU86711A1 (fr)
NL (1) NL8603132A (fr)
NO (1) NO178718C (fr)
NZ (1) NZ218499A (fr)
PT (1) PT83894B (fr)
SE (1) SE468831B (fr)

Families Citing this family (25)

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Publication number Priority date Publication date Assignee Title
IL81370A (en) * 1986-02-07 1991-06-30 Genetic Systems Corp Pharmaceutical and diagnostic compositions comprising a plurality of human monoclonal antibodies for the treatment of bacterial diseases,methods for the preparation of the compositions and antibodies and kits containing said compositions
AU615162B2 (en) * 1986-07-03 1991-09-26 Genetic Systems Corporation Monoclonal antibodies to pseudomonas aeruginosa flagella
EP0256713A3 (fr) * 1986-08-06 1989-02-15 Merck & Co. Inc. Anticorps humains thérapeutiques anti-pseudomonas aeruginosa
EP0327648B1 (fr) * 1986-12-15 1993-06-09 MITSUI TOATSU CHEMICALS, Inc. Anticorps monoclonal humain et medicament pour la prophylaxie et le traitement de maladies infectieuses comprenant ledit anticorps en tant qu'ingredient efficace
US5521085A (en) * 1986-12-15 1996-05-28 Mitsui Toatsu Chemicals, Inc. Transformed cell lines producing human monoclonal antibodies specific for Pseudomonas aeruginosa serotypes
JPH01197500A (ja) * 1988-01-29 1989-08-09 Sumitomo Chem Co Ltd ヒトモノクローナル抗体
GB2218703B (en) * 1988-05-10 1992-10-28 Sumitomo Chemical Co Human monoclonal antibody to p.aeruginosa: its production and use
CA1341375C (fr) * 1988-10-12 2002-07-09 Baxter International Inc. Compositions pour le traitement et la prevention d'infections dues a des bacteries gram negatif, ainsi que leurs methodes d'utilisation
EP0382031A3 (fr) * 1989-02-10 1991-06-26 Miles Inc. Anticorps monoclonaux dans une préparation de globuline d'immunsérum
US4994269A (en) * 1989-03-17 1991-02-19 Miles Inc. Topical use of antibodies for prevention or treatment of pseudomonas infections
AU619672B2 (en) * 1989-03-20 1992-01-30 Mitsui Toatsu Chemicals Inc. Human monoclonal antibody reactive with pseudomonas aeruginosa, cell which produces the antibody, method of production, and pharmaceutical preparation
JPH02283294A (ja) * 1989-04-24 1990-11-20 Sumitomo Chem Co Ltd ヒトモノクローナル抗体
AU5675790A (en) * 1989-05-09 1990-11-29 Cetus Corporation Human monoclonal antibodies to sero-specific determinants of gram-negative bacteria
US5858728A (en) * 1991-03-13 1999-01-12 Common Services Agency Monoclonal antibody against LPS core
US20030096315A1 (en) 2000-05-03 2003-05-22 Sanders Mitchell C. Device for detecting bacterial contamination and method of use
US9017963B2 (en) * 2002-01-31 2015-04-28 Woundchek Laboratories (Us), Inc. Method for detecting microorganisms
CA2493863A1 (fr) * 2002-05-29 2003-12-11 Harvey B. Pollard Ensembles permettant d'identifier des biomarqueurs proteomiques et genomiques pour la fibrose kystique
WO2004047778A1 (fr) 2002-11-26 2004-06-10 Uc Tech Materiaux et procedes pour la prevention et le traitement de troubles epitheliaux a mediation microbienne
CA2514938A1 (fr) * 2003-01-31 2004-10-14 Ethicon, Inc. Methode de detection d'escherichia coli
DE602004011105T2 (de) * 2003-11-03 2008-12-18 Ethicon, Inc. Verfahren, peptide und biosensoren mit eignung zum nachweis eines breiten spektrums von bakterien
EP1690875A1 (fr) * 2005-02-14 2006-08-16 Kenta Biotech AG Anticorps monoclonal humain specifique pour lipoplysaccharides (LPS) de la Pseudomonas aeruginosa serotype IATS O11
MX2008013895A (es) * 2006-05-01 2009-01-29 Bioness Neuromodulation Ltd Sistemas de estimulacion electrica funcionales mejorados.
JP2012516897A (ja) * 2009-02-04 2012-07-26 カロバイオス ファーマシューティカルズ インコーポレイティッド シュードモナス・エルギノーサ（ＰｓｅｕｄｏｍｏｎａｓＡｅｒｕｇｉｎｏｓａ）感染の治療のための抗生物質と抗体療法との組み合わせ
KR20120128688A (ko) * 2010-02-18 2012-11-27 심포젠 에이/에스 녹농균의 혈청형 ｉ 지질다당류에 대한 항체
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH652145A5 (de) * 1982-01-22 1985-10-31 Sandoz Ag Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.
US4464465A (en) * 1982-04-05 1984-08-07 Genetic Systems Corporation Cell-driven viral transfer in eukaryotes
JPS59137497A (ja) * 1983-01-20 1984-08-07 ザ・リ−ジエンツ・オブ・ザ・ユニバ−シテイ・オブ・カリフオルニア 抗原特異的免疫グロブリン生産性ヒト／ヒトハイブリド−マ及びその生産する抗体
JPS58216125A (ja) * 1982-06-09 1983-12-15 Asahi Chem Ind Co Ltd ヒト抗体の産生方法
JPS5929622A (ja) * 1982-08-10 1984-02-16 Meiji Seika Kaisha Ltd モノクロ−ナル抗体、その製造法およびその用途
DE3484773D1 (de) * 1983-05-06 1991-08-08 Velos Group Mit endotoxinkern reaktionsfaehige monoklonale antikoerper.
US4587121A (en) * 1983-06-14 1986-05-06 Miles Laboratories, Inc. High titer Pseudomonas immune serum globulin
US5179018A (en) * 1983-10-14 1993-01-12 Centocor, Inc. Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria
EP0168422A1 (fr) * 1983-12-12 1986-01-22 Meru, Inc. Procede et substances permettant l'identification de micro-organismes produisant du lipopolysaccharide
US4683196A (en) * 1983-12-12 1987-07-28 Meru, Inc. Method and materials for the identification of lipopolysaccharide producing microorganisms
JP2565303B2 (ja) * 1984-05-25 1996-12-18 三井東圧化学株式会社 緑膿菌感染症の予防治療剤
JPS60248625A (ja) * 1984-05-25 1985-12-09 Mitsui Toatsu Chem Inc 抗緑膿菌モノクロ−ナル抗体、その製法ならびに用途
US4834975A (en) * 1984-05-25 1989-05-30 Genetics Corporation Human monoclonal antibodies to serotypic lipopolysaccharide determinants on gram-negative bacteria and their production
DE3426903A1 (de) * 1984-07-20 1986-01-23 Biotest Pharma GmbH, 6000 Frankfurt Eine immunglobulinpraeparation in kombination mit einer anderen pharmakologisch wirksamen praeparation zur verwendung bei der behandlung von krankheiten
AU597877B2 (en) * 1984-12-26 1990-06-14 Teijin Limited Anti-pseudomonas aeruginosa human monoclonal antibody
US4677070A (en) * 1985-04-26 1987-06-30 Cetus Corporation Pseudomonas aeruginosa exotoxin A antibodies, their preparation and use
JPS6229175A (ja) * 1985-07-29 1987-02-07 Nippon Telegr & Teleph Corp <Ntt> 電界効果型トランジスタの製造方法
US4772464A (en) * 1985-08-01 1988-09-20 Miles Laboratories, Inc. Protective antibodies to serotypic determinants of flagellar antigens
DE3689713T2 (de) * 1985-08-01 1994-07-07 Miles Inc Schützende Antikörper gegen serotypische Determinanten von flagellären Antigenen.
US4777136A (en) * 1985-09-27 1988-10-11 The Regents Of The University Of California Monoclonal antibody reactive with Pseudomonas Aeruginosa
US4970070A (en) * 1986-02-07 1990-11-13 Genetic Systems Corporation Protective monoclonal antibody compositions for infections due to group B streptococcus
AU615162B2 (en) * 1986-07-03 1991-09-26 Genetic Systems Corporation Monoclonal antibodies to pseudomonas aeruginosa flagella
EP0256713A3 (fr) * 1986-08-06 1989-02-15 Merck & Co. Inc. Anticorps humains thérapeutiques anti-pseudomonas aeruginosa

Also Published As

Publication number Publication date
DE3642095A1 (de) 1987-07-02
CN86108380A (zh) 1987-10-28
NO864971L (no) 1987-06-11
US5628996A (en) 1997-05-13
HUT41836A (en) 1987-05-28
FI865027A0 (fi) 1986-12-10
KR910008361B1 (ko) 1991-10-12
DK594586A (da) 1987-06-11
SE8605295D0 (sv) 1986-12-10
GB2185266B (en) 1990-09-05
SE468831B (sv) 1993-03-29
FI865027A (fi) 1987-06-11
JPS62187417A (ja) 1987-08-15
NL8603132A (nl) 1987-07-01
FR2593826B1 (fr) 1990-11-16
GB8629540D0 (en) 1987-01-21
LU86711A1 (fr) 1988-07-14
US5662905A (en) 1997-09-02
NO864971D0 (no) 1986-12-10
US5627067A (en) 1997-05-06
FR2593826A1 (fr) 1987-08-07
KR870005648A (ko) 1987-07-06
GB2185266A (en) 1987-07-15
NO178718B (no) 1996-02-12
ATA328286A (de) 1995-05-15
CH677362A5 (fr) 1991-05-15
US5378812A (en) 1995-01-03
DK594586D0 (da) 1986-12-10
NO178718C (no) 1996-05-22
IT1199735B (it) 1988-12-30
PT83894B (pt) 1989-07-31
NZ218499A (en) 1990-04-26
PT83894A (en) 1987-01-01
IT8622630A0 (it) 1986-12-10
SE8605295L (sv) 1987-06-11
AT400441B (de) 1995-12-27
IE59741B1 (en) 1994-03-23
JPH07116237B2 (ja) 1995-12-13
FI86377B (fi) 1992-05-15
IE863230L (en) 1987-06-10
DE3642095C2 (de) 1998-10-01
FI86377C (fi) 1992-08-25

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: GENETIC SYSTEMS CORP.

Effective date: 20001231