BE866697A - Liposomes et procedes pour les produire - Google Patents

Liposomes et procedes pour les produire

Info

Publication number
BE866697A
BE866697A BE187387A BE187387A BE866697A BE 866697 A BE866697 A BE 866697A BE 187387 A BE187387 A BE 187387A BE 187387 A BE187387 A BE 187387A BE 866697 A BE866697 A BE 866697A
Authority
BE
Belgium
Prior art keywords
liposomes
producing
methods
Prior art date
Application number
BE187387A
Other languages
English (en)
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of BE866697A publication Critical patent/BE866697A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
BE187387A 1977-05-10 1978-05-03 Liposomes et procedes pour les produire BE866697A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB19510/77A GB1575343A (en) 1977-05-10 1977-05-10 Method for preparing liposome compositions containing biologically active compounds

Publications (1)

Publication Number Publication Date
BE866697A true BE866697A (fr) 1978-11-03

Family

ID=10130587

Family Applications (1)

Application Number Title Priority Date Filing Date
BE187387A BE866697A (fr) 1977-05-10 1978-05-03 Liposomes et procedes pour les produire

Country Status (19)

Country Link
US (2) US4311712A (fr)
JP (1) JPS53142514A (fr)
AU (1) AU514644B2 (fr)
BE (1) BE866697A (fr)
CA (1) CA1114758A (fr)
CH (2) CH652615A5 (fr)
DE (1) DE2818655A1 (fr)
DK (2) DK156765C (fr)
FI (1) FI63856C (fr)
FR (1) FR2390159A1 (fr)
GB (1) GB1575343A (fr)
IE (1) IE46571B1 (fr)
IL (2) IL54270A (fr)
IT (1) IT1094811B (fr)
NL (1) NL7805005A (fr)
NO (3) NO150184C (fr)
NZ (1) NZ186696A (fr)
SE (3) SE440725B (fr)
ZA (1) ZA781416B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2441385A1 (fr) * 1978-11-17 1980-06-13 Serono Ist Farm Procede de preparation extemporanee de liposomes et liposomes ainsi obtenus

Families Citing this family (121)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH621479A5 (fr) * 1977-08-05 1981-02-13 Battelle Memorial Institute
IT1110989B (it) * 1979-01-19 1986-01-13 Erba Farmitalia Forme farmaceutiche costitutite da liposomi e procedimenti relativi
FR2416008A1 (fr) * 1978-02-02 1979-08-31 Oreal Lyophilisats de liposomes
JPS55118415A (en) * 1979-02-28 1980-09-11 Pii Papahadojiyopo Dometoriosu Method of encapsulating biologically active substance in lipoid cell
DE2914789A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Injizierbare arzneimittel mit entzuendungshemmender wirkung
DE2914788A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Parenteral applizierbare, stabile arzneimittelloesungen mit entzuendungshemmender wirkung
JPS55153713A (en) * 1979-05-02 1980-11-29 Kureha Chem Ind Co Ltd Pharmaceutical preparation of ribosome containing active substance
CA1173360A (fr) * 1979-06-22 1984-08-28 Jurg Schrank Produits pharmaceutiques
US4310505A (en) * 1979-11-08 1982-01-12 California Institute Of Technology Lipid vesicles bearing carbohydrate surfaces as lymphatic directed vehicles for therapeutic and diagnostic substances
HU184141B (en) * 1979-12-27 1984-07-30 Human Oltoanyagtermelo Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof
JPS5775916A (en) * 1980-10-29 1982-05-12 Nippon Chemiphar Co Ltd Coenzyme q pharmaceutical and its preparation
JPS57146710A (en) * 1981-03-07 1982-09-10 Kunio Yagi Blood brain-barrier permeating ribosome-like microcapsule
US4397846A (en) * 1981-05-15 1983-08-09 Murray Weiner Storage-stable lipid vesicles and method of preparation
JPS58128318A (ja) * 1982-01-22 1983-07-30 フアイソンズ・ピ−エルシ− 薬学的組成物
JPS58222014A (ja) * 1982-06-18 1983-12-23 Taisho Pharmaceut Co Ltd プロスタグランジンｅ↓１脂肪乳剤
US4588578A (en) * 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
GB8322178D0 (en) * 1983-08-17 1983-09-21 Sterwin Ag Preparing aerosol compositions
US4744989A (en) * 1984-02-08 1988-05-17 E. R. Squibb & Sons, Inc. Method of preparing liposomes and products produced thereby
US5141674A (en) * 1984-03-08 1992-08-25 Phares Pharmaceutical Research N.V. Methods of preparing pro-liposome dispersions and aerosols
JPS60208910A (ja) * 1984-03-31 1985-10-21 Green Cross Corp:The 水難溶性薬物・リン脂質複合体の製造方法
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters
US5736155A (en) * 1984-08-08 1998-04-07 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
US5077056A (en) * 1984-08-08 1991-12-31 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
DE3582905D1 (de) * 1984-08-10 1991-06-27 Syntex Inc Stabile liposome mit wasserloeslichen arzneimitteln.
JPS6150912A (ja) * 1984-08-16 1986-03-13 Shionogi & Co Ltd リポソ−ム製剤の製造法
JPS61100518A (ja) * 1984-10-22 1986-05-19 Ono Pharmaceut Co Ltd ジミリストイルホスフアチジルコリンを主成分とする凍結乾燥されたリポゾ−ム製剤
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US4830858A (en) * 1985-02-11 1989-05-16 E. R. Squibb & Sons, Inc. Spray-drying method for preparing liposomes and products produced thereby
US5409704A (en) * 1985-06-26 1995-04-25 The Liposome Company, Inc. Liposomes comprising aminoglycoside phosphates and methods of production and use
FR2591105B1 (fr) * 1985-12-11 1989-03-24 Moet Hennessy Rech Composition pharmaceutique, notamment dermatologique, ou cosmetique, a base de phases lamellaires lipidiques hydratees ou de liposomes contenant un retinoide ou un analogue structural dudit retinoide tel qu'un carotenoide.
US5068198A (en) * 1986-03-26 1991-11-26 Syntex (U.S.A.) Inc. Liquid single reagent for assays involving confining gels
SE8601457D0 (sv) * 1986-04-01 1986-04-01 Draco Ab Compositions of liposomes and b?712-receptor active substances for inhalation
FR2597345B1 (fr) * 1986-04-22 1990-08-03 Oreal Composition cosmetique ou pharmaceutique a base d'une dispersion aqueuse de spherules lipidiques.
SE8603812D0 (sv) * 1986-09-12 1986-09-12 Draco Ab Administration of liposomes to mammals
US4891324A (en) * 1987-01-07 1990-01-02 Syntex (U.S.A.) Inc. Particle with luminescer for assays
US5089181A (en) * 1987-02-24 1992-02-18 Vestar, Inc. Method of dehydrating vesicle preparations for long term storage
US5811119A (en) * 1987-05-19 1998-09-22 Board Of Regents, The University Of Texas Formulation and use of carotenoids in treatment of cancer
US5262168A (en) * 1987-05-22 1993-11-16 The Liposome Company, Inc. Prostaglandin-lipid formulations
US5925375A (en) * 1987-05-22 1999-07-20 The Liposome Company, Inc. Therapeutic use of multilamellar liposomal prostaglandin formulations
AU617678B2 (en) * 1987-05-22 1991-12-05 Liposome Company, Inc., The Prostaglandin-lipid formulations
US4963362A (en) * 1987-08-07 1990-10-16 Regents Of The University Of Minnesota Freeze-dried liposome mixture containing cyclosporin
US5178875A (en) * 1991-01-14 1993-01-12 The Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
US5830498A (en) * 1987-10-16 1998-11-03 Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
US4950432A (en) * 1987-10-16 1990-08-21 Board Of Regents, The University Of Texas System Polyene microlide pre-liposomal powders
US4981690A (en) * 1987-10-27 1991-01-01 Board Of Regents, The University Of Texas System Liposome-incorporated mepartricin
JPH0610131B2 (ja) * 1987-10-30 1994-02-09 テルモ株式会社 リポソームの製法
EP0397774A1 (fr) * 1988-02-04 1990-11-22 Board Of Regents, The University Of Texas System Formulation et utilisation de retinoides dans le traitement du cancer et d'autres maladies
US5096629A (en) * 1988-08-29 1992-03-17 501 Nippon Fine Chemical Co., Ltd. Method for preparing lipid powder for use in preparing liposomes and method for preparing liposomes
WO1990004412A1 (fr) * 1988-10-27 1990-05-03 Regents Of The University Of Minnesota Immunoadjuvants liposomiques contenant de l'il-2
US5174988A (en) * 1989-07-27 1992-12-29 Scientific Development & Research, Inc. Phospholipid delivery system
IN172208B (fr) * 1990-04-02 1993-05-01 Sint Sa
US20040208826A1 (en) * 1990-04-02 2004-10-21 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US7083778B2 (en) * 1991-05-03 2006-08-01 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US20010024638A1 (en) * 1992-11-02 2001-09-27 Michel Schneider Stable microbubble suspensions as enhancement agents for ultrasound echography and dry formulations thereof
US6613306B1 (en) 1990-04-02 2003-09-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
USRE39146E1 (en) 1990-04-02 2006-06-27 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US6989141B2 (en) * 1990-05-18 2006-01-24 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5578292A (en) 1991-11-20 1996-11-26 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US5445813A (en) * 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
US20030194376A1 (en) * 1990-05-18 2003-10-16 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
ES2089227T3 (es) * 1990-07-31 1996-10-01 Liposome Co Inc Acumulacion de aminoacidos y peptidos en el interior de liposomas.
US5340716A (en) * 1991-06-20 1994-08-23 Snytex (U.S.A.) Inc. Assay method utilizing photoactivated chemiluminescent label
US6251581B1 (en) 1991-05-22 2001-06-26 Dade Behring Marburg Gmbh Assay method utilizing induced luminescence
US5885260A (en) 1991-05-30 1999-03-23 Mehl, Sr.; Thomas L. Freeze-dried liposome delivery system for application of skin treatment agents
EP0660714B1 (fr) * 1991-06-18 2003-07-02 ImaRx Pharmaceutical Corp. Nouveaux systemes d'apport de medicaments aux liposomes
FR2681781A1 (fr) * 1991-09-30 1993-04-02 Oreal Composition cosmetique anhydre de maquillage comprenant une phase grasse et procede de traitement cosmetique utilisant cette composition.
AU3423493A (en) * 1991-12-31 1993-07-28 Zymogenetics Inc. Methods and compositions for reducing blood loss
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them
USRE37224E1 (en) * 1992-06-05 2001-06-12 Dalhousie University Method to prevent fertilization in mammals by administering a single dose of zona pellucida derived antigens, liposome and adjuvant
US5736141A (en) * 1992-06-05 1998-04-07 Dalhousie University Method to prevent fertilization in mammals by administering a single dose of zona pellucida derived antigens, liposome and Freund's adjuvant
CA2141451C (fr) * 1992-07-31 2003-10-07 John S. Pease Matrices chimioluminescentes pouvant etre photoactivees
DE4309579C3 (de) * 1993-03-24 2000-01-27 Sanol Arznei Schwarz Gmbh Pharmazeutische Zusammensetzung in Form einer Packung
DE69409361T2 (de) 1993-11-05 1998-11-12 Amgen Inc Herstellung von liposomen und verfahren zur substanzverkapselung
RU2138293C1 (ru) * 1993-12-15 1999-09-27 Бракко Рисерч С.А. Контрастные вещества для ультразвуковой эхографии, контрастные средства, содержащие эти вещества, и способы их приготовления
IT1269569B (it) * 1994-04-22 1997-04-08 Ugo Citernesi Procedimento per la preparazione di complessi fra fosfolipidi e principi attivi utili per la produzione di liposomi e principi attivi e liposomi ottenuti con il procedimento
US6156337A (en) * 1994-07-08 2000-12-05 Opperbas Holding B.V. Method for high loading of vesicles with biopolymeric substances
IL115099A (en) * 1994-10-14 1999-04-11 Upjohn Co Lyophilizate of phospholipid complex of water insoluble camptothecins
US5990077A (en) 1995-04-14 1999-11-23 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
US6184201B1 (en) 1995-04-14 2001-02-06 Nps Allelix Corp. Intestinotrophic glucagon-like peptide-2 analogs
US5834428A (en) * 1995-04-14 1998-11-10 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
US5902604A (en) 1995-06-06 1999-05-11 Board Of Regents, The University Of Texas System Submicron liposome suspensions obtained from preliposome lyophilizates
NZ332281A (en) 1996-04-12 2000-03-27 Allelix Biopharma Glucagon-like peptide-2 (GLP-2) analogs for the treatment of bowl disorders resistant to dipeptidyl peptidase IV (DPP-IV) digestion
US6111081A (en) * 1996-05-31 2000-08-29 Baylor College Of Medicine Lactoferrin variants and uses thereof
EP0936860B1 (fr) * 1996-10-25 2002-02-20 Monsanto Technology LLC Composition permettant de traiter des vegetaux avec des substances chimiques exogenes et technique afferente
CA2269726A1 (fr) 1996-10-25 1998-04-30 Monsanto Company Composition et procede utilises pour traiter des plantes au moyen de produits chimiques exogenes
US6037125A (en) * 1996-11-05 2000-03-14 Lexicon Genetics Incorporated Disruption of the mammalian RAD51 protein and disruption of proteins that associate with mammalian RAD51 for hindering cell proliferation and/or viability of proliferating cells
CA2236519C (fr) 1997-05-02 2011-09-13 1149336 Ontario Inc. Methodes pour ameliorer le fonctionnement du gros intestin
SK7092003A3 (en) * 2000-11-09 2004-06-08 Neopharm Inc SN-38 lipid complexes and methods of use
AU3169702A (en) * 2000-12-07 2002-06-18 Yamanouchi Europ Bv Composition for treatment of inflammatory disorders
WO2003030864A1 (fr) * 2001-05-29 2003-04-17 Neopharm, Inc. Formulation liposomale d'irinotecan
US6939564B2 (en) * 2001-06-08 2005-09-06 Labopharm, Inc. Water-soluble stabilized self-assembled polyelectrolytes
US6780324B2 (en) * 2002-03-18 2004-08-24 Labopharm, Inc. Preparation of sterile stabilized nanodispersions
US20040082521A1 (en) * 2002-03-29 2004-04-29 Azaya Therapeutics Inc. Novel formulations of digitalis glycosides for treating cell-proliferative and other diseases
US20030212046A1 (en) * 2002-05-07 2003-11-13 Kapac, Llc Methods and formulations for enhancing the absorption and gastro-intestinal bioavailability of hydrophobic drugs
US20060093661A1 (en) * 2002-05-07 2006-05-04 Kapac, Llc Methods and formulations for enhancing the absorption and gastro-intestinal bioavailability of hydrophobic drugs
US20050152962A1 (en) * 2002-06-12 2005-07-14 Metselaar Josbert M. Composition for treatment of inflammatory disorders
US20060030578A1 (en) * 2002-08-20 2006-02-09 Neopharm, Inc. Pharmaceutically active lipid based formulation of irinotecan
WO2004035032A2 (fr) * 2002-08-20 2004-04-29 Neopharm, Inc. Formulation de sn-38 a base de lipides pharmaceutiquement actifs
EP1393720A1 (fr) * 2002-08-27 2004-03-03 Universiteit Utrecht Vesicules encapsulant des corticosteroides pour le traitement du cancer
KR100651728B1 (ko) * 2004-11-10 2006-12-06 한국전자통신연구원 정착기를 갖는 전자 소자용 화합물 및 이를 포함하는 전자소자와 이들의 제조 방법
US20060198891A1 (en) 2004-11-29 2006-09-07 Francois Ravenelle Solid formulations of liquid biologically active agents
US20080045575A1 (en) * 2004-12-29 2008-02-21 Van Dyke Thomas E Delivery of H2 Antagonists
ATE454134T1 (de) 2005-04-13 2010-01-15 Abbott Gmbh & Co Kg Verfahren zur schonenden herstellung hochfeiner partikelsuspensionen und hochfeiner partikel sowie deren verwendung
DE102005017777A1 (de) * 2005-04-13 2006-10-19 Pharmasol Gmbh Verfahren zur schonenden Herstellung von hochfeinen Partikelsuspensionen
MX2009003092A (es) * 2006-09-22 2009-05-08 Labopharm Inc Composiciones y metodos para suministro de farmaco dirigido a ph.
US7960336B2 (en) 2007-08-03 2011-06-14 Pharmain Corporation Composition for long-acting peptide analogs
US9168288B2 (en) 2010-04-09 2015-10-27 Mount Sinai Hospital Methods for treating disorders of the gastrointestinal tract using a GLP-1 agonist
AU2011353698B2 (en) 2011-01-05 2017-05-11 Livon Laboratories Methods of making liposomes, liposome compositions made by the methods, and methods of using the same
EP4219534A3 (fr) 2013-07-08 2023-09-27 The University of Utah Research Foundation Procédés de traitement et de prophylatise contre les troubles inflammatoires
US10772926B2 (en) 2016-12-16 2020-09-15 Nutragen Health Innovations, Inc. Natural drugs for the treatment of inflammation and melanoma
WO2018204918A1 (fr) 2017-05-05 2018-11-08 Ardelyx, Inc. Traitement de troubles hépatiques
JP2021518401A (ja) 2018-03-21 2021-08-02 コロラド ステート ユニバーシティー リサーチ ファウンデーション がんワクチン組成物及びその使用方法
RU2740553C2 (ru) * 2019-01-30 2021-01-15 Анастасия Андреевна Карбаинова Способ получения липосомальной формы бетулина, обладающей гепатопротекторной активностью
LT6699B (lt) 2019-07-15 2020-02-10 UAB "Valentis" Proliposomų gamybos būdas, naudojant ne daugiau kaip 5 % etanolio, ir jų panaudojimas lipofilinių medžiagų kapsuliavimui
EP4114456A1 (fr) 2020-03-06 2023-01-11 The Colorado State University Research Foundation Production de vaccins comprenant des particules virales de sras-cov-2 inactivées
AU2021314955A1 (en) 2020-07-28 2023-03-30 Jazz Pharmaceuticals Ireland Limited Fused bicyclic Raf inhibitors and methods for use thereof
CN116348465A (zh) 2020-07-28 2023-06-27 爵士制药爱尔兰有限公司 稠合双环raf抑制剂的手性合成
EP4312536A1 (fr) 2021-04-01 2024-02-07 Vestaron Corporation Formulations de liposomes destinées à l'administration de pesticides et leurs procédés de production et d'utilisation
WO2023096858A1 (fr) 2021-11-23 2023-06-01 Senda Biosciences, Inc. Composition lipidique dérivée de bactéries et son utilisation

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3549382A (en) * 1968-05-15 1970-12-22 Francis Frederick Hansen Method of preparing powdered monoglyceride material
FR2081586A2 (en) * 1970-01-24 1971-12-10 Orsymonde Dehydrated pharmaceutical comps by - lyophilisation
US3597455A (en) * 1969-05-29 1971-08-03 Squibb & Sons Inc Process for manufacture of sterile lecithin
FR2101044A2 (en) * 1969-11-26 1972-03-31 Orsymonde Freeze-dried oil - in - water emulsions - for treatment of mouth , teeth, hair and scalp
CH558659A (fr) * 1969-11-26 1975-02-14 Orsymonde Procede pour la preparation d'une composition lyophilisee a usage hygienique.
DE2249552A1 (de) * 1971-10-12 1973-05-30 Inchema S A Verfahren zur inkapsulation von insbesondere wasserloeslichen verbindungen
BE795516A (fr) * 1972-02-17 1973-08-16 Ciba Geigy Preparations de peptides huileuses et injectables et procede pour leur preparation
CH588887A5 (fr) * 1974-07-19 1977-06-15 Battelle Memorial Institute
US3957971A (en) * 1974-07-29 1976-05-18 Lever Brothers Company Moisturizing units and moisturizing compositions containing the same
JPS5126213A (ja) * 1974-08-21 1976-03-04 Tanabe Seiyaku Co Johoseibiryushiseizaino seiho
JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
FR2315991A1 (fr) * 1975-06-30 1977-01-28 Oreal Procede de fabrication de dispersions aqueuses de spherules lipidiques et nouvelles compositions correspondantes
DK141082B (da) * 1976-01-13 1980-01-14 Battelle Memorial Institute Fremgangsmåde til fremstilling af liposomer indeholdende biologisk aktivt stof dispergeret i et vandigt medium.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2441385A1 (fr) * 1978-11-17 1980-06-13 Serono Ist Farm Procede de preparation extemporanee de liposomes et liposomes ainsi obtenus

Also Published As

Publication number Publication date
IT1094811B (it) 1985-08-10
NO153121B (no) 1985-10-14
SE440725B (sv) 1985-08-19
DE2818655C2 (fr) 1987-05-14
IT7823207A0 (it) 1978-05-10
NZ186696A (en) 1980-10-08
DE2818655A1 (de) 1978-11-23
IE780464L (en) 1978-11-10
CA1114758A (fr) 1981-12-22
DK122388A (da) 1988-03-07
NO840064L (no) 1978-11-13
US4370349A (en) 1983-01-25
NL7805005A (nl) 1978-11-14
GB1575343A (en) 1980-09-17
SE453962B (sv) 1988-03-21
DK206578A (da) 1978-11-11
DK122388D0 (da) 1988-03-07
AU3423578A (en) 1979-09-20
ZA781416B (en) 1979-03-28
US4311712A (en) 1982-01-19
AU514644B2 (en) 1981-02-19
DK156765B (da) 1989-10-02
CH650944A5 (de) 1985-08-30
FI63856C (fi) 1983-09-12
IL54270A (en) 1981-06-29
FR2390159A1 (fr) 1978-12-08
SE7805276L (sv) 1978-11-11
IL61475A0 (en) 1980-12-31
DK156765C (da) 1990-02-19
JPS6252724B2 (fr) 1987-11-06
IL54270A0 (en) 1978-06-15
JPS53142514A (en) 1978-12-12
CH652615A5 (de) 1985-11-29
NO780838L (no) 1978-11-13
NO834219L (no) 1978-11-13
SE8201350L (sv) 1982-03-04
NO153121C (no) 1986-01-22
FI63856B (fi) 1983-05-31
NO150184B (no) 1984-05-28
FR2390159B1 (fr) 1983-01-14
IE46571B1 (en) 1983-07-27
NO150184C (no) 1984-09-05
SE454049B (sv) 1988-03-28
SE8201351L (sv) 1982-03-04
FI781012A (fi) 1978-11-11

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