AU758475B2 - Biodegradable low molecular weight triblock polyester polyethylene glycol copolymers having reverse thermal gelation properties - Google Patents

Biodegradable low molecular weight triblock polyester polyethylene glycol copolymers having reverse thermal gelation properties Download PDF

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Publication number
AU758475B2
AU758475B2 AU10983/00A AU1098300A AU758475B2 AU 758475 B2 AU758475 B2 AU 758475B2 AU 10983/00 A AU10983/00 A AU 10983/00A AU 1098300 A AU1098300 A AU 1098300A AU 758475 B2 AU758475 B2 AU 758475B2
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AU
Australia
Prior art keywords
drug
polymer
lactide
block
biodegradable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU10983/00A
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English (en)
Other versions
AU1098300A (en
Inventor
Byeongmoon Jeong
Ramesh C. Rathi
Gaylen M. Zentner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
MacroMed Inc
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Filing date
Publication date
Priority claimed from US09/164,865 external-priority patent/US6117949A/en
Application filed by MacroMed Inc filed Critical MacroMed Inc
Publication of AU1098300A publication Critical patent/AU1098300A/en
Application granted granted Critical
Publication of AU758475B2 publication Critical patent/AU758475B2/en
Assigned to BTG INTERNATIONAL LIMITED reassignment BTG INTERNATIONAL LIMITED Alteration of Name(s) in Register under S187 Assignors: MACROMED, INC.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/91—Polymers modified by chemical after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66—Polyesters containing oxygen in the form of ether groups
    • C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AU10983/00A 1998-10-01 1999-09-30 Biodegradable low molecular weight triblock polyester polyethylene glycol copolymers having reverse thermal gelation properties Ceased AU758475B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/164,865 US6117949A (en) 1998-10-01 1998-10-01 Biodegradable low molecular weight triblock poly (lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
US09/164865 1998-10-01
US09/396,589 US6201072B1 (en) 1997-10-03 1999-09-15 Biodegradable low molecular weight triblock poly(lactide-co- glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
US09/396589 1999-09-15
PCT/US1999/022755 WO2000018821A1 (en) 1998-10-01 1999-09-30 Biodegradable low molecular weight triblock polyester polyethylene glycol copolymers having reverse thermal gelation properties

Publications (2)

Publication Number Publication Date
AU1098300A AU1098300A (en) 2000-04-17
AU758475B2 true AU758475B2 (en) 2003-03-20

Family

ID=26860925

Family Applications (1)

Application Number Title Priority Date Filing Date
AU10983/00A Ceased AU758475B2 (en) 1998-10-01 1999-09-30 Biodegradable low molecular weight triblock polyester polyethylene glycol copolymers having reverse thermal gelation properties

Country Status (19)

Country Link
US (1) US6201072B1 (enExample)
EP (1) EP1141079B1 (enExample)
JP (1) JP4628545B2 (enExample)
KR (1) KR100558025B1 (enExample)
CN (1) CN1161396C (enExample)
AT (1) ATE378365T1 (enExample)
AU (1) AU758475B2 (enExample)
BR (1) BR9914258B1 (enExample)
CA (1) CA2345659C (enExample)
CY (1) CY1107888T1 (enExample)
DK (1) DK1141079T3 (enExample)
ES (1) ES2301250T3 (enExample)
IL (1) IL142313A0 (enExample)
NO (1) NO332941B1 (enExample)
NZ (1) NZ510832A (enExample)
PL (1) PL205127B1 (enExample)
RU (1) RU2232779C2 (enExample)
TR (1) TR200100900T2 (enExample)
WO (1) WO2000018821A1 (enExample)

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TR200100900T2 (tr) 2001-10-22
KR20010083880A (ko) 2001-09-03
ES2301250T3 (es) 2008-06-16
WO2000018821A1 (en) 2000-04-06
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EP1141079A1 (en) 2001-10-10
JP4628545B2 (ja) 2011-02-09
ATE378365T1 (de) 2007-11-15
CN1161396C (zh) 2004-08-11
BR9914258B1 (pt) 2014-07-15
US6201072B1 (en) 2001-03-13
IL142313A0 (en) 2002-03-10
EP1141079A4 (en) 2004-03-24
NO332941B1 (no) 2013-02-04
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DK1141079T3 (da) 2008-03-25
NO20011639D0 (no) 2001-03-30

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