AU611938B2 - Thiazolidinedione derivatives - Google Patents

Thiazolidinedione derivatives Download PDF

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Publication number
AU611938B2
AU611938B2 AU21738/88A AU2173888A AU611938B2 AU 611938 B2 AU611938 B2 AU 611938B2 AU 21738/88 A AU21738/88 A AU 21738/88A AU 2173888 A AU2173888 A AU 2173888A AU 611938 B2 AU611938 B2 AU 611938B2
Authority
AU
Australia
Prior art keywords
amino
formula
methyl
thiazolidinedione
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired, expires
Application number
AU21738/88A
Other languages
English (en)
Other versions
AU2173888A (en
Inventor
Richard Mark Hindley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27263577&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU611938(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB878720825A external-priority patent/GB8720825D0/en
Priority claimed from GB878727987A external-priority patent/GB8727987D0/en
Priority claimed from GB888802454A external-priority patent/GB8802454D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of AU2173888A publication Critical patent/AU2173888A/en
Application granted granted Critical
Publication of AU611938B2 publication Critical patent/AU611938B2/en
Adjusted expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
AU21738/88A 1987-09-04 1988-09-02 Thiazolidinedione derivatives Expired AU611938B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB878720825A GB8720825D0 (en) 1987-09-04 1987-09-04 Compounds
GB878727987A GB8727987D0 (en) 1987-11-30 1987-11-30 Novel compounds
GB8720825 1988-02-04
GB8802454 1988-02-04
GB888802454A GB8802454D0 (en) 1988-02-04 1988-02-04 Compounds
GB8727987 1988-02-04

Publications (2)

Publication Number Publication Date
AU2173888A AU2173888A (en) 1989-03-09
AU611938B2 true AU611938B2 (en) 1991-06-27

Family

ID=27263577

Family Applications (1)

Application Number Title Priority Date Filing Date
AU21738/88A Expired AU611938B2 (en) 1987-09-04 1988-09-02 Thiazolidinedione derivatives

Country Status (18)

Country Link
US (1) US5002953A (instruction)
EP (2) EP0306228B1 (instruction)
JP (6) JP2614497B2 (instruction)
KR (1) KR0164207B1 (instruction)
AT (1) ATE186724T1 (instruction)
AU (1) AU611938B2 (instruction)
CA (1) CA1328452C (instruction)
CZ (1) CZ391691A3 (instruction)
DE (2) DE10199003I1 (instruction)
DK (2) DK175176B1 (instruction)
ES (1) ES2137915T3 (instruction)
GR (1) GR3031873T3 (instruction)
IE (1) IE20000683A1 (instruction)
LU (1) LU90711I2 (instruction)
NL (1) NL300034I2 (instruction)
NZ (1) NZ226027A (instruction)
PT (1) PT88410B (instruction)
SG (1) SG59988A1 (instruction)

Families Citing this family (274)

* Cited by examiner, † Cited by third party
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EP3568134A1 (en) 2017-01-16 2019-11-20 Institut National de la Sante et de la Recherche Medicale (INSERM) Methods and pharmaceutical compositions for reducing cd95- mediated cell motility
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DE10199003I2 (instruction) 2003-09-18
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NZ226027A (en) 1992-03-26
CA1328452C (en) 1994-04-12
DE10199003I1 (de) 2003-06-12
HK1011029A1 (en) 1999-07-02
NL300034I2 (nl) 2001-05-01
JPH09183726A (ja) 1997-07-15
PT88410A (pt) 1989-07-31
US5002953A (en) 1991-03-26
JP2614497B2 (ja) 1997-05-28
DE3856378D1 (de) 1999-12-23
DK175176B1 (da) 2004-06-21
JPH09183771A (ja) 1997-07-15
LU90711I2 (fr) 2001-03-05
JP2837139B2 (ja) 1998-12-14
KR0164207B1 (ko) 1999-01-15
PT88410B (pt) 1992-10-30
EP0842925A1 (en) 1998-05-20
JP2817840B2 (ja) 1998-10-30
DK200001556A (da) 2000-10-18
GR3031873T3 (en) 2000-02-29
JPH10194970A (ja) 1998-07-28
IE20000683A1 (en) 2002-07-24
SG59988A1 (en) 1999-02-22
CZ391691A3 (en) 1993-03-17
JPH01131169A (ja) 1989-05-24
DE3856378T2 (de) 2000-05-11
JPH09183772A (ja) 1997-07-15
DK490288D0 (da) 1988-09-02
EP0306228B1 (en) 1999-11-17
AU2173888A (en) 1989-03-09
EP0306228A1 (en) 1989-03-08
ATE186724T1 (de) 1999-12-15
ES2137915T3 (es) 2000-01-01
DK490288A (da) 1989-03-05
JPH10194971A (ja) 1998-07-28

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