AU2021214911A1 - Methods for treating SARS CoV-2 infections - Google Patents

Methods for treating SARS CoV-2 infections Download PDF

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Publication number
AU2021214911A1
AU2021214911A1 AU2021214911A AU2021214911A AU2021214911A1 AU 2021214911 A1 AU2021214911 A1 AU 2021214911A1 AU 2021214911 A AU2021214911 A AU 2021214911A AU 2021214911 A AU2021214911 A AU 2021214911A AU 2021214911 A1 AU2021214911 A1 AU 2021214911A1
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AU
Australia
Prior art keywords
additional therapeutic
therapeutic agent
alkyl
formula
group
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Abandoned
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AU2021214911A
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English (en)
Inventor
Tomas Cihlar
Anuoluwapo OSINUSI
Danielle L. PORTER
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Gilead Sciences Inc
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Gilead Sciences Inc
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Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of AU2021214911A1 publication Critical patent/AU2021214911A1/en
Priority to AU2024205205A priority Critical patent/AU2024205205A1/en
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2021214911A 2020-01-27 2021-01-26 Methods for treating SARS CoV-2 infections Abandoned AU2021214911A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2024205205A AU2024205205A1 (en) 2020-01-27 2024-07-30 Methods for treating SARS CoV-2 infections

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202062966440P 2020-01-27 2020-01-27
US62/966,440 2020-01-27
US202062976671P 2020-02-14 2020-02-14
US62/976,671 2020-02-14
US202062985194P 2020-03-04 2020-03-04
US62/985,194 2020-03-04
US202063031373P 2020-05-28 2020-05-28
US63/031,373 2020-05-28
PCT/US2021/015027 WO2021154687A1 (en) 2020-01-27 2021-01-26 Methods for treating sars cov-2 infections

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2024205205A Division AU2024205205A1 (en) 2020-01-27 2024-07-30 Methods for treating SARS CoV-2 infections

Publications (1)

Publication Number Publication Date
AU2021214911A1 true AU2021214911A1 (en) 2022-07-21

Family

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AU2021214911A Abandoned AU2021214911A1 (en) 2020-01-27 2021-01-26 Methods for treating SARS CoV-2 infections
AU2024205205A Pending AU2024205205A1 (en) 2020-01-27 2024-07-30 Methods for treating SARS CoV-2 infections

Family Applications After (1)

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AU2024205205A Pending AU2024205205A1 (en) 2020-01-27 2024-07-30 Methods for treating SARS CoV-2 infections

Country Status (9)

Country Link
US (2) US11660307B2 (https=)
EP (2) EP4096678A1 (https=)
JP (2) JP2023512656A (https=)
KR (1) KR20220132608A (https=)
CN (3) CN118766947A (https=)
AU (2) AU2021214911A1 (https=)
CA (1) CA3163424A1 (https=)
TW (2) TWI789695B (https=)
WO (1) WO2021154687A1 (https=)

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WO2021154687A1 (en) 2021-08-05
CN118766947A (zh) 2024-10-15
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AU2024205205A1 (en) 2024-08-15
US11660307B2 (en) 2023-05-30
JP2026004417A (ja) 2026-01-14
EP4096678A1 (en) 2022-12-07
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TW202140046A (zh) 2021-11-01
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