SI1954264T1 - Postopek priprave intermediatov epoksibutanola - Google Patents
Postopek priprave intermediatov epoksibutanolaInfo
- Publication number
- SI1954264T1 SI1954264T1 SI200630502T SI200630502T SI1954264T1 SI 1954264 T1 SI1954264 T1 SI 1954264T1 SI 200630502 T SI200630502 T SI 200630502T SI 200630502 T SI200630502 T SI 200630502T SI 1954264 T1 SI1954264 T1 SI 1954264T1
- Authority
- SI
- Slovenia
- Prior art keywords
- manufacture
- formula
- epoxybutanol
- intermediates
- ethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/08—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05026163 | 2005-12-01 | ||
EP06804890A EP1954264B1 (en) | 2005-12-01 | 2006-11-29 | Process for the manufacture of epoxybutanol intermediates |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1954264T1 true SI1954264T1 (sl) | 2010-01-29 |
Family
ID=36178579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200630502T SI1954264T1 (sl) | 2005-12-01 | 2006-11-29 | Postopek priprave intermediatov epoksibutanola |
Country Status (19)
Country | Link |
---|---|
US (2) | US7816537B2 (sl) |
EP (2) | EP1954264B1 (sl) |
JP (1) | JP5329969B2 (sl) |
KR (1) | KR101191682B1 (sl) |
CN (1) | CN101321522B (sl) |
AT (1) | ATE444747T1 (sl) |
AU (2) | AU2006319657B2 (sl) |
BR (1) | BRPI0619120B1 (sl) |
CA (2) | CA2711852C (sl) |
CY (1) | CY1110588T1 (sl) |
DE (1) | DE602006009698D1 (sl) |
DK (1) | DK1954264T3 (sl) |
ES (1) | ES2333258T3 (sl) |
HR (1) | HRP20090675T1 (sl) |
PL (1) | PL1954264T3 (sl) |
PT (1) | PT1954264E (sl) |
SI (1) | SI1954264T1 (sl) |
WO (1) | WO2007062542A2 (sl) |
ZA (1) | ZA200804218B (sl) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2480559E (pt) | 2009-09-21 | 2013-10-02 | Gilead Sciences Inc | Processos e intermediários para a preparação de análogos de 1'-ciano-carbanucleósido |
UA111163C2 (uk) | 2010-07-22 | 2016-04-11 | Гайлід Сайєнсіз, Інк. | Способи й сполуки для лікування вірусних інфекцій paramyxoviridae |
SI2882723T1 (sl) | 2012-08-07 | 2017-04-26 | Basilea Pharmaceutica Ag | Postopek izdelave izavukonazola ali ravukonazola |
WO2015150947A1 (en) | 2014-03-29 | 2015-10-08 | Wockhardt Limited | A process for the preparation of isavuconazole and its intermediates |
TWI740546B (zh) | 2014-10-29 | 2021-09-21 | 美商基利科學股份有限公司 | 製備核糖苷的方法 |
EP3785717B1 (en) | 2015-09-16 | 2022-01-05 | Gilead Sciences, Inc. | Methods for treating coronaviridae infections |
CN105367528A (zh) * | 2015-11-10 | 2016-03-02 | 南通诺泰生物医药技术有限公司 | 一种三唑类药物中间体(d)-1-(1-环烷仲胺基)-2-(2-四氢吡喃基)氧-1-丙酮类化合物及合成方法 |
ES2961460T3 (es) | 2017-03-14 | 2024-03-12 | Gilead Sciences Inc | Métodos para tratar las infecciones por coronavirus felinas |
WO2018204198A1 (en) | 2017-05-01 | 2018-11-08 | Gilead Sciences, Inc. | Crystalline forms of (s) 2 ethylbutyl 2 (((s) (((2r,3s,4r,5r) 5 (4 aminopyrrolo[2,1-f] [1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2 yl)methoxy)(phenoxy) phosphoryl)amino)propanoate |
US10675296B2 (en) | 2017-07-11 | 2020-06-09 | Gilead Sciences, Inc. | Compositions comprising an RNA polymerase inhibitor and cyclodextrin for treating viral infections |
ES2915582T3 (es) | 2017-08-10 | 2022-06-23 | Sumitomo Chemical Co | Método para producir un compuesto de alcohol epoxi |
US11660307B2 (en) | 2020-01-27 | 2023-05-30 | Gilead Sciences, Inc. | Methods for treating SARS CoV-2 infections |
WO2021183750A2 (en) | 2020-03-12 | 2021-09-16 | Gilead Sciences, Inc. | Methods of preparing 1'-cyano nucleosides |
WO2021207049A1 (en) | 2020-04-06 | 2021-10-14 | Gilead Sciences, Inc. | Inhalation formulations of 1'-cyano substituted carbanucleoside analogs |
EP4157272A1 (en) | 2020-05-29 | 2023-04-05 | Gilead Sciences, Inc. | Remdesivir treatment methods |
MX2022016405A (es) | 2020-06-24 | 2023-01-30 | Gilead Sciences Inc | Análogos de nucleósido de 1¿-ciano y usos de estos. |
JP2023540225A (ja) | 2020-08-27 | 2023-09-22 | ギリアード サイエンシーズ, インコーポレイテッド | ウイルス感染症の治療のための化合物及び方法 |
TW202400185A (zh) | 2022-03-02 | 2024-01-01 | 美商基利科學股份有限公司 | 用於治療病毒感染的化合物及方法 |
CN115536643A (zh) * | 2022-12-05 | 2022-12-30 | 南京桦冠生物技术有限公司 | 一种艾沙康唑类药物关键中间体的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3452213B2 (ja) * | 1994-07-05 | 2003-09-29 | エーザイ株式会社 | 抗真菌剤及びその製造方法 |
WO1999045008A1 (en) * | 1998-03-06 | 1999-09-10 | F. Hoffmann-La Roche Ag | 3-[4-(4-cyanophenyl)thiazol-2-y)]-1-(1h-1,2,4-triazol-1-yl)-butan-2-ol derivatives having antifungal activity |
US6133485A (en) | 1998-04-15 | 2000-10-17 | Synphar Laboratories, Inc. | Asymmetric synthesis of 2-(2,4-difluorophenyl)-1-heterocycl-1-yl butan-2,3-diols |
US6391903B1 (en) | 1999-09-09 | 2002-05-21 | Sankyo Company, Limited | Triazole derivatives having antifungal activity |
US6884892B2 (en) | 2002-06-20 | 2005-04-26 | Sumitomo Chemical Company, Limited | Production methods of epoxytriazole derivative and intermediate therefor |
JP4627413B2 (ja) * | 2003-05-06 | 2011-02-09 | 三井化学株式会社 | 1−アゾール−2−フェニル−2、3−プロパンジオール誘導体の製造法 |
-
2006
- 2006-11-29 KR KR1020087015976A patent/KR101191682B1/ko active IP Right Grant
- 2006-11-29 PT PT06804890T patent/PT1954264E/pt unknown
- 2006-11-29 DE DE602006009698T patent/DE602006009698D1/de active Active
- 2006-11-29 JP JP2008542575A patent/JP5329969B2/ja active Active
- 2006-11-29 WO PCT/CH2006/000671 patent/WO2007062542A2/en active Application Filing
- 2006-11-29 BR BRPI0619120-7A patent/BRPI0619120B1/pt active IP Right Grant
- 2006-11-29 CA CA2711852A patent/CA2711852C/en active Active
- 2006-11-29 CA CA2629092A patent/CA2629092C/en active Active
- 2006-11-29 ES ES06804890T patent/ES2333258T3/es active Active
- 2006-11-29 EP EP06804890A patent/EP1954264B1/en active Active
- 2006-11-29 PL PL06804890T patent/PL1954264T3/pl unknown
- 2006-11-29 AT AT06804890T patent/ATE444747T1/de active
- 2006-11-29 US US12/085,617 patent/US7816537B2/en active Active
- 2006-11-29 SI SI200630502T patent/SI1954264T1/sl unknown
- 2006-11-29 CN CN2006800449743A patent/CN101321522B/zh active Active
- 2006-11-29 EP EP09168177A patent/EP2133345A1/en not_active Withdrawn
- 2006-11-29 AU AU2006319657A patent/AU2006319657B2/en active Active
- 2006-11-29 DK DK06804890T patent/DK1954264T3/da active
-
2008
- 2008-05-15 ZA ZA200804218A patent/ZA200804218B/xx unknown
-
2009
- 2009-12-17 HR HR20090675T patent/HRP20090675T1/hr unknown
- 2009-12-29 CY CY20091101343T patent/CY1110588T1/el unknown
-
2010
- 2010-07-23 AU AU2010203301A patent/AU2010203301B2/en active Active
- 2010-08-31 US US12/872,599 patent/US8076494B2/en active Active
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