AU2012240110B2 - Method for the generation of compact tale-nucleases and uses thereof - Google Patents
Method for the generation of compact tale-nucleases and uses thereof Download PDFInfo
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- AU2012240110B2 AU2012240110B2 AU2012240110A AU2012240110A AU2012240110B2 AU 2012240110 B2 AU2012240110 B2 AU 2012240110B2 AU 2012240110 A AU2012240110 A AU 2012240110A AU 2012240110 A AU2012240110 A AU 2012240110A AU 2012240110 B2 AU2012240110 B2 AU 2012240110B2
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Priority Applications (1)
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| AU2017248447A AU2017248447B2 (en) | 2011-04-05 | 2017-10-17 | Method for the generation of compact tale-nucleases and uses thereof |
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| US9023594B2 (en) | 2008-09-05 | 2015-05-05 | President And Fellows Of Harvard College | Continuous directed evolution of proteins and nucleic acids |
| US20110201118A1 (en) * | 2010-06-14 | 2011-08-18 | Iowa State University Research Foundation, Inc. | Nuclease activity of tal effector and foki fusion protein |
| AU2011348204B2 (en) | 2010-12-22 | 2017-03-02 | President And Fellows Of Harvard College | Continuous directed evolution |
| EP2732038B1 (en) | 2011-07-15 | 2018-09-05 | The General Hospital Corporation | Methods of transcription activator like effector assembly |
| JP6261500B2 (ja) | 2011-07-22 | 2018-01-17 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ヌクレアーゼ切断特異性の評価および改善 |
| EP2758537A4 (en) * | 2011-09-23 | 2015-08-12 | Univ Iowa State Res Found | MONOERARY TECHNIQUE OF TAL NUCLEASE OR ZINC FINGERUCLEASE FOR DNA MODIFICATION |
| US20130210151A1 (en) | 2011-11-07 | 2013-08-15 | University Of Western Ontario | Endonuclease for genome editing |
| CA2854819C (en) | 2011-11-16 | 2022-07-19 | Sangamo Biosciences, Inc. | Modified dna-binding proteins and uses thereof |
| US9688997B2 (en) | 2011-12-29 | 2017-06-27 | Iowa State University Research Foundation, Inc. | Genetically modified plants with resistance to Xanthomonas and other bacterial plant pathogens |
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US11778993B2 (en) * | 2012-03-15 | 2023-10-10 | Cellectis, S.A. | Repeat variable diresidues for targeting nucleotides |
| ES2828663T3 (es) * | 2012-04-18 | 2021-05-27 | Univ Leland Stanford Junior | Dirección genética no disruptiva |
| US11518997B2 (en) | 2012-04-23 | 2022-12-06 | BASF Agricultural Solutions Seed US LLC | Targeted genome engineering in plants |
| CN111676196A (zh) | 2012-05-25 | 2020-09-18 | 塞勒克提斯公司 | 工程化异体和免疫抑制耐受性t细胞的方法 |
| US20150017136A1 (en) | 2013-07-15 | 2015-01-15 | Cellectis | Methods for engineering allogeneic and highly active t cell for immunotherapy |
| US9890364B2 (en) | 2012-05-29 | 2018-02-13 | The General Hospital Corporation | TAL-Tet1 fusion proteins and methods of use thereof |
| EP2855671B1 (en) | 2012-06-05 | 2019-02-20 | Cellectis | Transcription activator-like effector (tale) fusion protein |
| EP2861737B1 (en) | 2012-06-19 | 2019-04-17 | Regents Of The University Of Minnesota | Gene targeting in plants using dna viruses |
| US9091827B2 (en) | 2012-07-09 | 2015-07-28 | Luxtera, Inc. | Method and system for grating couplers incorporating perturbed waveguides |
| DK2893004T3 (en) | 2012-09-04 | 2019-02-04 | Cellectis | MULTI-CHAIN CHEMICAL ANTIGEN RECEPTOR AND APPLICATIONS THEREOF |
| CN103668470B (zh) * | 2012-09-12 | 2015-07-29 | 上海斯丹赛生物技术有限公司 | 一种dna文库及构建转录激活子样效应因子核酸酶质粒的方法 |
| EP2906602B1 (en) | 2012-10-12 | 2019-01-16 | The General Hospital Corporation | Transcription activator-like effector (tale) - lysine-specific demethylase 1 (lsd1) fusion proteins |
| WO2014065596A1 (en) | 2012-10-23 | 2014-05-01 | Toolgen Incorporated | Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof |
| BR112015009812A2 (pt) | 2012-10-31 | 2017-08-22 | Cellectis | Método para a inserção genética específica em um genoma de planta, célula de planta transformada e seu uso, planta resistente a herbicidas, kit, vetor, e célula hospedeira |
| BR122019025681B1 (pt) * | 2012-11-01 | 2023-04-18 | Factor Bioscience Inc | Método para inserir uma sequência de ácido nucleico em uma localização segura de um genoma de uma célula |
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| IN2015DN04148A (OSRAM) | 2012-11-16 | 2015-10-16 | Total Marketing Services | |
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| JP6346266B2 (ja) * | 2013-03-21 | 2018-06-20 | サンガモ セラピューティクス， インコーポレイテッド | 操作されたジンクフィンガータンパク質ヌクレアーゼを使用するｔ細胞受容体遺伝子の標的化された破壊 |
| US20160053274A1 (en) | 2013-04-02 | 2016-02-25 | Bayer Cropscience Nv | Targeted genome engineering in eukaryotes |
| WO2014169810A1 (zh) * | 2013-04-16 | 2014-10-23 | 深圳华大基因科技服务有限公司 | 分离的寡核苷酸及其用途 |
| AU2014266833B2 (en) | 2013-05-13 | 2020-07-02 | Cellectis | Methods for engineering highly active T cell for immunotherapy |
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| CN105916983A (zh) * | 2013-10-25 | 2016-08-31 | 塞勒克提斯公司 | 用于高效且特异性靶向包含高度重复基序的dna序列的稀有切割核酸内切酶的设计 |
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