AU2012229300B2 - Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione - Google Patents

Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione Download PDF

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AU2012229300B2
AU2012229300B2 AU2012229300A AU2012229300A AU2012229300B2 AU 2012229300 B2 AU2012229300 B2 AU 2012229300B2 AU 2012229300 A AU2012229300 A AU 2012229300A AU 2012229300 A AU2012229300 A AU 2012229300A AU 2012229300 B2 AU2012229300 B2 AU 2012229300B2
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lymphoma
compound
cell
patient
quinazolin
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AU2012229300A1 (en
Inventor
Rajesh Chopra
Anita GANDHI
Hon-Wah Man
George W. Muller
Peter H. Schafer
Ling-hua ZHANG
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Celgene Corp
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Celgene Corp
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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AU2012229300A 2011-03-11 2012-03-09 Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione Ceased AU2012229300B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2017204402A AU2017204402A1 (en) 2011-03-11 2017-06-28 Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione

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US201161451995P 2011-03-11 2011-03-11
US61/451,995 2011-03-11
US201161480272P 2011-04-28 2011-04-28
US61/480,272 2011-04-28
PCT/US2012/028498 WO2012125459A1 (en) 2011-03-11 2012-03-09 Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione

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AU2017204402A Division AU2017204402A1 (en) 2011-03-11 2017-06-28 Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione

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AU2012229300A1 AU2012229300A1 (en) 2013-09-12
AU2012229300B2 true AU2012229300B2 (en) 2017-04-20

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AU2012229316A Ceased AU2012229316B2 (en) 2011-03-11 2012-03-09 Use of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2-6-dione in treatment of immune-related and inflammatory diseases
AU2012229300A Ceased AU2012229300B2 (en) 2011-03-11 2012-03-09 Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione
AU2017204402A Abandoned AU2017204402A1 (en) 2011-03-11 2017-06-28 Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione
AU2017210633A Abandoned AU2017210633A1 (en) 2011-03-11 2017-08-04 Use of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4h)-yl)piperidine-2-6-dione in treatment of immune-related and inflammatory diseases

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AU2012229316A Ceased AU2012229316B2 (en) 2011-03-11 2012-03-09 Use of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2-6-dione in treatment of immune-related and inflammatory diseases

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AU2017204402A Abandoned AU2017204402A1 (en) 2011-03-11 2017-06-28 Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione
AU2017210633A Abandoned AU2017210633A1 (en) 2011-03-11 2017-08-04 Use of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4h)-yl)piperidine-2-6-dione in treatment of immune-related and inflammatory diseases

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US20120134969A1 (en) 2009-05-25 2012-05-31 Hiroshi Handa Pharmaceutical composition containing nuclear factor involved in proliferation and differentiation of central neuronal cells
EA026100B1 (ru) 2011-03-11 2017-03-31 Селджин Корпорейшн Твердые формы 3-(5-амино-2-метил-4-оксо-4н-хиназолин-3-ил)пиперидин-2,6-диона и их фармацевтические композиции и применение
AU2012236655B2 (en) 2011-03-28 2016-09-22 Deuterx, Llc, 2',6'-dioxo-3'-deutero-piperdin-3-yl-isoindoline compounds
CN103688176A (zh) * 2011-04-29 2014-03-26 细胞基因公司 利用cereblon作为预报因子治疗癌和炎性疾病的方法
ES2872967T3 (es) 2012-06-29 2021-11-03 Celgene Corp Métodos para determinar la eficacia de fármacos usando IKZF3 (AIOLOS)
EP2882442B1 (en) * 2012-08-09 2021-06-09 Celgene Corporation Methods of treating cancer using 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
US9587281B2 (en) 2012-08-14 2017-03-07 Celgene Corporation Cereblon isoforms and their use as biomarkers for therapeutic treatment
US9682952B2 (en) 2012-09-04 2017-06-20 Celgene Corporation Isotopologues of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl) piperidine-2-6-dione and methods of preparation thereof
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