AU2008229076B2 - Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors - Google Patents
Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors Download PDFInfo
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- AU2008229076B2 AU2008229076B2 AU2008229076A AU2008229076A AU2008229076B2 AU 2008229076 B2 AU2008229076 B2 AU 2008229076B2 AU 2008229076 A AU2008229076 A AU 2008229076A AU 2008229076 A AU2008229076 A AU 2008229076A AU 2008229076 B2 AU2008229076 B2 AU 2008229076B2
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- C—CHEMISTRY; METALLURGY
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D3/00—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
- B01D3/001—Processes specially adapted for distillation or rectification of fermented solutions
- B01D3/002—Processes specially adapted for distillation or rectification of fermented solutions by continuous methods
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
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- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/52—Propionic acid; Butyric acids
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- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01061—4-Hydroxybutyrate dehydrogenase (1.1.1.61)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01016—Succinate-semialdehyde dehydrogenase [NAD(P)+] (1.2.1.16)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01076—Succinate-semialdehyde dehydrogenase (acetylating) (1.2.1.76)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01071—2-Oxoglutarate decarboxylase (4.1.1.71)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y602/00—Ligases forming carbon-sulfur bonds (6.2)
- C12Y602/01—Acid-Thiol Ligases (6.2.1)
- C12Y602/01004—Succinate-CoA ligase (GDP-forming) (6.2.1.4)
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2013204038A AU2013204038B2 (en) | 2007-03-16 | 2013-04-11 | Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors |
| AU2013204409A AU2013204409A1 (en) | 2007-03-16 | 2013-04-12 | Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91846307P | 2007-03-16 | 2007-03-16 | |
| US60/918,463 | 2007-03-16 | ||
| PCT/US2008/057168 WO2008115840A2 (en) | 2007-03-16 | 2008-03-14 | Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2013204038A Division AU2013204038B2 (en) | 2007-03-16 | 2013-04-11 | Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors |
| AU2013204409A Division AU2013204409A1 (en) | 2007-03-16 | 2013-04-12 | Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2008229076A1 AU2008229076A1 (en) | 2008-09-25 |
| AU2008229076B2 true AU2008229076B2 (en) | 2014-05-15 |
Family
ID=39766721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2008229076A Active AU2008229076B2 (en) | 2007-03-16 | 2008-03-14 | Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors |
Country Status (13)
| Country | Link |
|---|---|
| US (10) | US8067214B2 (https=) |
| EP (4) | EP2821494B1 (https=) |
| JP (6) | JP5551448B2 (https=) |
| CN (2) | CN101668861A (https=) |
| AU (1) | AU2008229076B2 (https=) |
| BR (2) | BRPI0823327A2 (https=) |
| CA (1) | CA2678946C (https=) |
| ES (2) | ES2625439T3 (https=) |
| HU (1) | HUE032465T2 (https=) |
| LT (1) | LT2821494T (https=) |
| PL (2) | PL2821494T3 (https=) |
| TW (2) | TWI568847B (https=) |
| WO (1) | WO2008115840A2 (https=) |
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| US7947483B2 (en) * | 2007-08-10 | 2011-05-24 | Genomatica, Inc. | Methods and organisms for the growth-coupled production of 1,4-butanediol |
| US8026386B2 (en) * | 2007-08-10 | 2011-09-27 | Genomatica, Inc. | Methods for the synthesis of olefins and derivatives |
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| ES2656790T3 (es) * | 2008-03-27 | 2018-02-28 | Genomatica, Inc. | Microorganismos para la producción de ácido adípico y otros compuestos |
| WO2009135074A2 (en) | 2008-05-01 | 2009-11-05 | Genomatica, Inc. | Microorganisms for the production of methacrylic acid |
| BRPI0913901A2 (pt) | 2008-06-17 | 2016-12-13 | Genomatica Inc | micro-organismos e métodos para a biossíntese de fumarato, malato e acrilato |
| WO2010006076A2 (en) * | 2008-07-08 | 2010-01-14 | Opx Biotechnologies Inc. | Methods, compositions and systems for biosynthetic bio production of 1,4-butanediol |
| US20100021978A1 (en) * | 2008-07-23 | 2010-01-28 | Genomatica, Inc. | Methods and organisms for production of 3-hydroxypropionic acid |
| EP3514242A3 (en) * | 2008-09-10 | 2019-08-28 | Genomatica, Inc. | Microrganisms for the production of 1,4-butanediol |
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| EP2373781A4 (en) * | 2008-12-16 | 2012-10-10 | Genomatica Inc | MICRO-ORGANISMS AND METHODS OF CONVERTING SYNGAS AND OTHER CARBON RESOURCES IN USEFUL PRODUCTS |
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| MY176050A (en) | 2009-04-30 | 2020-07-22 | Genomatica Inc | Organisms for the production of 1,3-butanediol |
| BRPI1013505A2 (pt) | 2009-04-30 | 2018-02-14 | Genomatica Inc | organismos para a produção de isopropanol, n-butanol, e isobutanol |
| AU2013202628B2 (en) * | 2009-04-30 | 2016-03-10 | Genomatica, Inc. | Organisms for the production of 1,3-butanediol |
| EP2427544B1 (en) | 2009-05-07 | 2019-07-17 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid |
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| EP2440669A4 (en) * | 2009-06-10 | 2013-08-28 | Genomatica Inc | MICROOGANISMS AND PROCEDURES FOR THE CARBON EFFECTIVE BIOSYNTHESIS MEK AND 2-BUTANOL |
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| KR20120083908A (ko) * | 2009-10-13 | 2012-07-26 | 게노마티카 인코포레이티드 | 1,4-부탄다이올, 4-하이드록시부탄알, 4-하이드록시부티릴-coa, 푸트레신 및 관련 화합물의 제조를 위한 미생물 및 관련 방법 |
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