AU2002227984B8 - Novel sulfamides and their use as endothelin receptor antagonists - Google Patents

Novel sulfamides and their use as endothelin receptor antagonists Download PDF

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Publication number
AU2002227984B8
AU2002227984B8 AU2002227984A AU2002227984A AU2002227984B8 AU 2002227984 B8 AU2002227984 B8 AU 2002227984B8 AU 2002227984 A AU2002227984 A AU 2002227984A AU 2002227984 A AU2002227984 A AU 2002227984A AU 2002227984 B8 AU2002227984 B8 AU 2002227984B8
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acid
yloxy
phenyl
ethoxy
bromo
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AU2002227984A1 (en
AU2002227984B2 (en
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Martin Bolli
Christoph Boss
Martine Clozel
Walter Fischli
Thomas Weller
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Actelion Pharmaceuticals Ltd
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Actelion Pharmaceuticals Ltd
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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
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    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
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    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
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  • Organic Chemistry (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
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  • Communicable Diseases (AREA)
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  • Psychiatry (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
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AU2002227984A 2000-12-18 2001-12-04 Novel sulfamides and their use as endothelin receptor antagonists Active 2026-12-04 AU2002227984B8 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EPPCT/EP00/12890 2000-12-18
EP0012890 2000-12-18
PCT/EP2001/014182 WO2002053557A1 (en) 2000-12-18 2001-12-04 Novel sulfamides and their use as endothelin receptor antagonists

Publications (3)

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AU2002227984A1 AU2002227984A1 (en) 2002-07-16
AU2002227984B2 AU2002227984B2 (en) 2006-12-07
AU2002227984B8 true AU2002227984B8 (en) 2007-01-04

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AU2002227984A Active 2026-12-04 AU2002227984B8 (en) 2000-12-18 2001-12-04 Novel sulfamides and their use as endothelin receptor antagonists

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US (2) US7094781B2 (OSRAM)
EP (2) EP1693372A1 (OSRAM)
JP (1) JP4245130B2 (OSRAM)
KR (1) KR100819668B1 (OSRAM)
CN (1) CN100432070C (OSRAM)
AR (1) AR035610A1 (OSRAM)
AT (1) ATE323079T1 (OSRAM)
AU (1) AU2002227984B8 (OSRAM)
BE (1) BE2014C019I2 (OSRAM)
BR (1) BRPI0116237B8 (OSRAM)
CA (1) CA2431675C (OSRAM)
CY (2) CY1105060T1 (OSRAM)
DE (1) DE60118782T2 (OSRAM)
DK (1) DK1345920T3 (OSRAM)
ES (1) ES2260318T3 (OSRAM)
FR (1) FR14C0017I2 (OSRAM)
HU (1) HU229403B1 (OSRAM)
IL (2) IL155805A0 (OSRAM)
LU (1) LU92381I2 (OSRAM)
MX (1) MXPA03004780A (OSRAM)
MY (1) MY129150A (OSRAM)
NL (1) NL300672I2 (OSRAM)
NO (2) NO324952B1 (OSRAM)
NZ (1) NZ525614A (OSRAM)
PT (1) PT1345920E (OSRAM)
WO (1) WO2002053557A1 (OSRAM)
ZA (1) ZA200303695B (OSRAM)

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DE60236322D1 (de) * 2001-12-07 2010-06-17 Vertex Pharma Verbindungen auf pyrimidin-basis als gsk-3-hemmer
WO2004050640A1 (en) * 2002-12-02 2004-06-17 Actelion Pharmaceuticals Ltd Pyrimidine-sulfamides and their use as endothelian receptor antagonist
BR122018003623B8 (pt) 2004-03-05 2021-07-27 Hoffmann La Roche diaminopirimidinas, seus usos, e composição farmacêutica
UA90269C2 (ru) 2004-04-02 2010-04-26 Мицубиси Танабе Фарма Корпорейшн Тетрагидрохинолиновые производные и способ их получения
TW200628467A (en) 2004-11-11 2006-08-16 Actelion Pharmaceuticals Ltd Novel sulfamides
BRPI0614696A2 (pt) 2005-07-29 2011-04-12 Tibotec Pharm Ltd inibidores macrocìclicos de vìrus da hepatite c
AR055361A1 (es) 2005-07-29 2007-08-22 Medivir Ab Inhibidores macrociclicos del virus de la hepatitis c
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CN101253159B (zh) 2005-09-01 2011-12-07 弗·哈夫曼-拉罗切有限公司 作为p2x3和p2x2/3调节剂的二氨基嘧啶类化合物
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NZ567188A (en) 2005-09-12 2011-04-29 Actelion Pharmaceuticals Ltd Stable pharmaceutical composition comprising a pyrimidine-sulfamide
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MX2010001837A (es) 2007-08-17 2010-03-10 Actelion Pharmaceuticals Ltd Derivados de 4-pirimidinasulfamida.
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RU2494736C2 (ru) 2008-02-20 2013-10-10 Актелион Фармасьютиклз Лтд Комбинация, включающая паклитаксел, для лечения рака яичников
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WO2010113498A1 (ja) 2009-03-31 2010-10-07 興和株式会社 テトラヒドロキノリン化合物を有効成分とする貧血の予防及び／又は治療剤
TWI483938B (zh) 2009-08-10 2015-05-11 Univ Texas 以內皮素受體抑制劑處理星狀腫瘤細胞
CA2771190C (en) 2009-08-17 2020-01-21 Memorial Sloan-Kettering Cancer Center Heat shock protein binding compounds, compositions, and methods for making and using same
WO2011078143A1 (ja) * 2009-12-22 2011-06-30 塩野義製薬株式会社 ピリミジン誘導体およびそれらを含有する医薬組成物
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