ATE548657T1 - Prozedur zur strukturellen charakterisierung rekombinanter polyclonaler proteine oder einer polyclonalen zelllinie - Google Patents
Prozedur zur strukturellen charakterisierung rekombinanter polyclonaler proteine oder einer polyclonalen zelllinieInfo
- Publication number
- ATE548657T1 ATE548657T1 AT09151073T AT09151073T ATE548657T1 AT E548657 T1 ATE548657 T1 AT E548657T1 AT 09151073 T AT09151073 T AT 09151073T AT 09151073 T AT09151073 T AT 09151073T AT E548657 T1 ATE548657 T1 AT E548657T1
- Authority
- AT
- Austria
- Prior art keywords
- polyclonal
- cell line
- structural characterization
- procedure
- recombinant
- Prior art date
Links
- 238000012512 characterization method Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 238000012252 genetic analysis Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000012514 protein characterization Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Document Processing Apparatus (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200401133 | 2004-07-20 | ||
| DKPA200401991 | 2004-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE548657T1 true ATE548657T1 (de) | 2012-03-15 |
Family
ID=35427551
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05760790T ATE443870T1 (de) | 2004-07-20 | 2005-07-20 | Verfahren zur charakterisierung einer polyklonalen zellinie |
| AT09151073T ATE548657T1 (de) | 2004-07-20 | 2005-07-20 | Prozedur zur strukturellen charakterisierung rekombinanter polyclonaler proteine oder einer polyclonalen zelllinie |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05760790T ATE443870T1 (de) | 2004-07-20 | 2005-07-20 | Verfahren zur charakterisierung einer polyklonalen zellinie |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US8288109B2 (de) |
| EP (2) | EP2053408B1 (de) |
| JP (1) | JP4870667B2 (de) |
| KR (1) | KR101319848B1 (de) |
| AT (2) | ATE443870T1 (de) |
| AU (1) | AU2005263334C1 (de) |
| BR (1) | BRPI0513714A (de) |
| CA (1) | CA2574146C (de) |
| DE (1) | DE602005016818D1 (de) |
| DK (2) | DK1787126T3 (de) |
| ES (2) | ES2381531T3 (de) |
| IL (2) | IL180169A (de) |
| MX (1) | MX2007000551A (de) |
| NO (1) | NO20070931L (de) |
| NZ (1) | NZ552264A (de) |
| PL (2) | PL1787126T3 (de) |
| RU (1) | RU2426795C2 (de) |
| WO (1) | WO2006007853A2 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2512647C (en) | 2003-01-07 | 2013-10-08 | Symphogen A/S | Method for manufacturing recombinant polyclonal proteins |
| TWI333977B (en) | 2003-09-18 | 2010-12-01 | Symphogen As | Method for linking sequences of interest |
| NZ552265A (en) | 2004-07-20 | 2009-04-30 | Symphogen As | Anti-rhesus D recombinant polyclonal antibody and methods of manufacture |
| ATE443870T1 (de) | 2004-07-20 | 2009-10-15 | Symphogen As | Verfahren zur charakterisierung einer polyklonalen zellinie |
| US7850965B2 (en) | 2005-12-05 | 2010-12-14 | Symphogen A/S | Anti-orthopoxvirus recombinant polyclonal antibody |
| US8338376B2 (en) | 2006-10-20 | 2012-12-25 | Biogen Idec Ma Inc. | Compositions comprising variant LT-B-R-IG fusion proteins |
| NZ597466A (en) * | 2007-03-01 | 2013-08-30 | Symphogen As | Recombinant anti-epidermal growth factor receptor antibody compositions |
| PL2121920T3 (pl) * | 2007-03-01 | 2012-01-31 | Symphogen As | Sposób klonowania pokrewnych przeciwciał |
| BRPI0808673A2 (pt) | 2007-03-06 | 2014-08-12 | Symphogen A/S | Anticorpos recombinantes para tratamento de infecções com vírus sinciciais respiratórios. |
| CA2680792A1 (en) * | 2007-03-15 | 2008-09-18 | Biogen Idec Ma Inc. | Treatment of autoimmune disorders |
| JP2008289483A (ja) * | 2007-05-25 | 2008-12-04 | Symphogen As | 真核生物系において発現可能な形質転換体のスクリーニング |
| CA2683800C (en) | 2007-05-25 | 2015-03-17 | Symphogen A/S | Method for manufacturing a recombinant polyclonal protein |
| BRPI0817079A2 (pt) * | 2007-09-07 | 2016-10-11 | Symphogen As | processos para fabricação recombinante de anticorpos anti-rsv |
| AU2008328370A1 (en) * | 2007-11-22 | 2009-05-28 | Symphogen A/S | A method for characterization of a recombinant polyclonal protein |
| CN102007146A (zh) * | 2008-04-23 | 2011-04-06 | 西福根有限公司 | 用于制备多克隆蛋白质的方法 |
| AU2009287165A1 (en) * | 2008-08-29 | 2010-03-04 | Symphogen A/S | Method for cloning avian-derived antibodies |
| BRPI0918768B1 (pt) | 2008-08-29 | 2022-08-30 | Symphogen A/S | Composições de anticorpo recombinante de antireceptor do fator de crescimento epidérmico |
| US8821879B2 (en) | 2009-09-04 | 2014-09-02 | Xoma Technology Ltd. | Anti-botulism antibody coformulations |
| MX2012003538A (es) * | 2009-10-09 | 2012-08-03 | Symphogen As | Cuantificacion multiple de proteinas recombinantes individuales en una mezcla mediante peptidos distintivos y espectrometria de masas. |
| CA2796339C (en) * | 2010-04-15 | 2020-03-31 | Abbott Laboratories | Amyloid-beta binding proteins |
| EP2635604B1 (de) | 2010-11-01 | 2016-11-30 | Symphogen A/S | Pan-her-antikörperzusammensetzung |
| US9790269B2 (en) | 2013-02-08 | 2017-10-17 | Misfolding Diagnostics, Inc. | Transthyretin antibodies and uses thereof |
| DK3729958T3 (da) * | 2013-03-15 | 2023-08-07 | Mayo Found Medical Education & Res | Identificering og overvågning af monoklonale immunoglobuliner ved hjælp af molekylmasse |
| UY35517A (es) | 2013-04-04 | 2014-10-31 | Mabxience S A | Un procedimiento para aumentar la formación de ácido piroglutamico de una proteína |
| WO2015093925A1 (es) * | 2013-12-19 | 2015-06-25 | CASTRO ALDRETE, Jorge Isaac | Método de producción de anticuerpos específicos |
| TW201623331A (zh) * | 2014-03-12 | 2016-07-01 | 普羅帝納生物科學公司 | 抗黑色素瘤細胞黏著分子（ｍｃａｍ）抗體類及使用彼等之相關方法 |
| US11680948B2 (en) | 2016-08-12 | 2023-06-20 | Abreos Biosciences, Inc. | Detection and quantification of natalizumab |
| GB201710691D0 (en) * | 2017-07-04 | 2017-08-16 | Ge Healthcare Bio Sciences Ab | Method in bioprocess purification system |
| CA3104390A1 (en) * | 2018-06-22 | 2019-12-26 | Genmab A/S | Method for producing a controlled mixture of two or more different antibodies |
| CN112816595A (zh) * | 2021-01-06 | 2021-05-18 | 海默斯（重庆）医学生物技术有限公司 | 一种重组角蛋白液体制剂及其纯度检测方法 |
| WO2025038736A1 (en) * | 2023-08-15 | 2025-02-20 | Gigagen, Inc. | Methods of analyzing recombinant polyclonal proteins |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0162918A1 (de) | 1983-11-28 | 1985-12-04 | The Board Of Trustees Of The Leland Stanford Junior University | Menschlicher monoklonaler antikörper gegen das antigen rh(d) sowie dessen verwendungen |
| IL78775A (en) * | 1985-05-15 | 1992-06-21 | Biotech Australia Pty Ltd | Oral vaccines |
| CA1293460C (en) | 1985-10-07 | 1991-12-24 | Brian Lee Sauer | Site-specific recombination of dna in yeast |
| US5126130A (en) * | 1986-11-24 | 1992-06-30 | The Childrens Hospital Incorporated | Monoclonal antibodies reactive with specific antigenic sites on human cytomegalovirus glycoprotein a |
| GB8722020D0 (en) | 1987-09-18 | 1987-10-28 | Central Blood Lab Authority | Human anti-rh(d)monoclonal antibodies |
| GB8722018D0 (en) | 1987-09-18 | 1987-10-28 | Central Blood Lab Authority | Human anti-rh(d)monoclonal antibodies |
| GB8722019D0 (en) | 1987-09-18 | 1987-10-28 | Central Blood Lab Authority | Human anti-rh(d)monoclonal antibodies |
| ES2052027T5 (es) | 1988-11-11 | 2005-04-16 | Medical Research Council | Clonacion de secuencias de dominio variable de inmunoglobulina. |
| GB8906129D0 (en) | 1989-03-17 | 1989-05-04 | Central Blood Lab Authority | Pharmaceutical preparations |
| GB8919761D0 (en) | 1989-09-01 | 1989-10-18 | Central Blood Lab Authority | Chemical compounds |
| WO1992015694A1 (en) | 1991-03-08 | 1992-09-17 | The Salk Institute For Biological Studies | Flp-mediated gene modification in mammalian cells, and compositions and cells useful therefor |
| US5837268A (en) | 1991-10-16 | 1998-11-17 | University Of Saskatchewan | GnRH-leukotoxin chimeras |
| US5252216A (en) * | 1992-03-24 | 1993-10-12 | Smithkline Beecham Corporation | Protein purification |
| PL302438A1 (en) | 1992-06-26 | 1994-07-25 | Aetsrn | Human anti-rh(d) monoclonal antibodies and cellular lines producing them |
| US5538848A (en) * | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| DE69531148T2 (de) | 1994-01-31 | 2004-04-29 | Trustees Of Boston University, Boston | Bibliotheken aus polyklonalen antikörpern |
| FR2724182B1 (fr) * | 1994-09-02 | 1996-12-13 | Pasteur Institut | Obtention d'un anticorps monoclonal recombinant a partir d'un anticorps monoclonal humain anti-rhesus d, sa production en cellules d'insecte, et ses utilisations |
| US6111166A (en) | 1994-09-19 | 2000-08-29 | Medarex, Incorporated | Transgenic mice expressing human Fcα and β receptors |
| ES2224255T3 (es) | 1996-06-24 | 2005-03-01 | Zlb Behring Ag | Polipeptidos capaces de formar estructuras de union a antigenos con especificidad por los antigenos de rhesus d, el dna que los codifica y el proceso para su preparacion y uso. |
| US6255455B1 (en) * | 1996-10-11 | 2001-07-03 | The Trustees Of The University Of Pennsylvania | Rh(D)-binding proteins and magnetically activated cell sorting method for production thereof |
| US5876925A (en) * | 1996-10-11 | 1999-03-02 | The Trustees Of The University Of Pennsylvania | Magnetically activated cell sorting for production of proteins |
| AU737155B2 (en) | 1997-03-14 | 2001-08-09 | Biogen Idec Inc. | Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same |
| JPH11174038A (ja) * | 1997-12-10 | 1999-07-02 | Tosoh Corp | 蛋白質の分離精製法 |
| US6632672B2 (en) | 1998-08-19 | 2003-10-14 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for genomic modification |
| US20020155114A1 (en) * | 1998-08-31 | 2002-10-24 | James D. Marks | Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins |
| CA2379823A1 (en) * | 1999-07-16 | 2001-01-25 | Human Genome Sciences, Inc. | Real-time, in situ biomanufacturing process monitoring and control in response to ir spectroscopy |
| EP1234022B1 (de) | 1999-07-23 | 2010-04-07 | The Regents Of The University Of California | Dna-rekombination in eukaryotischen zellen mittels des rekombinationszentrums vom bakteriophag phic31 |
| EP1106625A1 (de) | 1999-11-17 | 2001-06-13 | ZLB Bioplasma AG | Rhesus D-spezifische Peptidsequenzen |
| CA2401663C (en) | 2000-02-08 | 2008-11-25 | The Regents Of The University Of Michigan | Protein mapping |
| AU2001234880A1 (en) | 2000-02-08 | 2001-08-20 | The Regents Of The University Of Michigan | Mapping of differential display of proteins |
| MXPA02007664A (es) | 2000-02-08 | 2004-08-23 | Univ Michigan | Separacion y representacion de proteinas. |
| CN1437482A (zh) | 2000-05-26 | 2003-08-20 | 西福根有限公司 | 用于治疗变态反应的重组的或纯化的多克隆抗体 |
| US6610472B1 (en) | 2000-10-31 | 2003-08-26 | Genetastix Corporation | Assembly and screening of highly complex and fully human antibody repertoire in yeast |
| US20040087014A1 (en) * | 2000-11-28 | 2004-05-06 | Huse William D | Eukaryotic expression libraries and methods of use |
| DE60119580T2 (de) * | 2000-12-26 | 2007-04-26 | The Institute For Systems Biology, Seattle | Schnelle und quantitative proteomanalyse und damit zusammenhängende verfahren |
| JP4264002B2 (ja) * | 2001-07-17 | 2009-05-13 | バイオ−ラド ラボラトリーズ インコーポレイテッド | ラテックスベース吸着チップ |
| GB2385918B (en) * | 2001-12-08 | 2004-05-26 | Micromass Ltd | Method of mass spectrometry |
| US20040033591A1 (en) | 2002-05-31 | 2004-02-19 | The Regents Of The University Of Michigan | Automated protein analysis system |
| ES2442615T5 (es) * | 2002-07-18 | 2023-03-16 | Merus Nv | Producción recombinante de mezclas de anticuerpos |
| JP2004101477A (ja) * | 2002-09-12 | 2004-04-02 | Yoshio Yamauchi | ２次元高速液体クロマトグラフ装置及びそれを用いた蛋白質分析装置 |
| WO2004035169A2 (en) | 2002-10-15 | 2004-04-29 | The Regents Of The University Of Michigan | Multidimensional protein separation system |
| US20060275766A1 (en) * | 2003-01-07 | 2006-12-07 | Haurum John S | Method for manufacturing recombinant polyclonal proteins |
| CA2512647C (en) | 2003-01-07 | 2013-10-08 | Symphogen A/S | Method for manufacturing recombinant polyclonal proteins |
| TWI333977B (en) | 2003-09-18 | 2010-12-01 | Symphogen As | Method for linking sequences of interest |
| NZ552265A (en) | 2004-07-20 | 2009-04-30 | Symphogen As | Anti-rhesus D recombinant polyclonal antibody and methods of manufacture |
| ATE443870T1 (de) | 2004-07-20 | 2009-10-15 | Symphogen As | Verfahren zur charakterisierung einer polyklonalen zellinie |
| US7850965B2 (en) | 2005-12-05 | 2010-12-14 | Symphogen A/S | Anti-orthopoxvirus recombinant polyclonal antibody |
| MX2008011280A (es) | 2006-03-06 | 2008-09-12 | Symphogen As | Anticuerpor policlonal recombinante para el tratamiento de infecciones por el virus sincitial respiratorio. |
| AU2008328370A1 (en) | 2007-11-22 | 2009-05-28 | Symphogen A/S | A method for characterization of a recombinant polyclonal protein |
-
2005
- 2005-07-20 AT AT05760790T patent/ATE443870T1/de active
- 2005-07-20 EP EP09151073A patent/EP2053408B1/de not_active Expired - Lifetime
- 2005-07-20 US US11/658,021 patent/US8288109B2/en not_active Expired - Fee Related
- 2005-07-20 NZ NZ552264A patent/NZ552264A/en not_active IP Right Cessation
- 2005-07-20 CA CA2574146A patent/CA2574146C/en not_active Expired - Fee Related
- 2005-07-20 DE DE602005016818T patent/DE602005016818D1/de not_active Expired - Lifetime
- 2005-07-20 ES ES09151073T patent/ES2381531T3/es not_active Expired - Lifetime
- 2005-07-20 BR BRPI0513714-4A patent/BRPI0513714A/pt not_active Application Discontinuation
- 2005-07-20 EP EP05760790A patent/EP1787126B1/de not_active Expired - Lifetime
- 2005-07-20 KR KR1020077003954A patent/KR101319848B1/ko not_active Expired - Fee Related
- 2005-07-20 PL PL05760790T patent/PL1787126T3/pl unknown
- 2005-07-20 PL PL09151073T patent/PL2053408T3/pl unknown
- 2005-07-20 AT AT09151073T patent/ATE548657T1/de active
- 2005-07-20 AU AU2005263334A patent/AU2005263334C1/en not_active Ceased
- 2005-07-20 WO PCT/DK2005/000504 patent/WO2006007853A2/en not_active Ceased
- 2005-07-20 DK DK05760790T patent/DK1787126T3/da active
- 2005-07-20 DK DK09151073.5T patent/DK2053408T3/da active
- 2005-07-20 JP JP2007521795A patent/JP4870667B2/ja not_active Expired - Fee Related
- 2005-07-20 ES ES05760790T patent/ES2332524T3/es not_active Expired - Lifetime
- 2005-07-20 MX MX2007000551A patent/MX2007000551A/es active IP Right Grant
- 2005-07-20 RU RU2007106050/10A patent/RU2426795C2/ru not_active IP Right Cessation
-
2006
- 2006-12-19 IL IL180169A patent/IL180169A/en not_active IP Right Cessation
-
2007
- 2007-02-19 NO NO20070931A patent/NO20070931L/no not_active Application Discontinuation
-
2009
- 2009-12-29 IL IL203017A patent/IL203017A/en not_active IP Right Cessation
-
2012
- 2012-10-16 US US13/653,316 patent/US9029091B2/en not_active Expired - Fee Related
Also Published As
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