ATE554390T1 - Verfahren zur gewinnung von antikörpern - Google Patents

Verfahren zur gewinnung von antikörpern

Info

Publication number
ATE554390T1
ATE554390T1 AT04768084T AT04768084T ATE554390T1 AT E554390 T1 ATE554390 T1 AT E554390T1 AT 04768084 T AT04768084 T AT 04768084T AT 04768084 T AT04768084 T AT 04768084T AT E554390 T1 ATE554390 T1 AT E554390T1
Authority
AT
Austria
Prior art keywords
antigen
obtaining antibodies
cells
antibody
enriching
Prior art date
Application number
AT04768084T
Other languages
English (en)
Inventor
Alastair D G Lawson
Meryn Ruth Griffiths
Original Assignee
Ucb Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0319587A external-priority patent/GB0319587D0/en
Priority claimed from GB0402641A external-priority patent/GB0402641D0/en
Application filed by Ucb Pharma Sa filed Critical Ucb Pharma Sa
Application granted granted Critical
Publication of ATE554390T1 publication Critical patent/ATE554390T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT04768084T 2003-08-20 2004-08-12 Verfahren zur gewinnung von antikörpern ATE554390T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0319587A GB0319587D0 (en) 2003-08-20 2003-08-20 Biological products
GB0402641A GB0402641D0 (en) 2004-02-06 2004-02-06 Antibodies
PCT/GB2004/003523 WO2005019824A1 (en) 2003-08-20 2004-08-12 Methods for obtaining antibodies

Publications (1)

Publication Number Publication Date
ATE554390T1 true ATE554390T1 (de) 2012-05-15

Family

ID=34219619

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04768084T ATE554390T1 (de) 2003-08-20 2004-08-12 Verfahren zur gewinnung von antikörpern

Country Status (5)

Country Link
US (2) US20060263353A1 (de)
EP (1) EP1658500B1 (de)
AT (1) ATE554390T1 (de)
ES (1) ES2385829T3 (de)
WO (1) WO2005019824A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0605965D0 (en) 2006-03-24 2006-05-03 Univ East Anglia Fluorescence based detection of substances
EP2021463B1 (de) 2006-05-19 2016-11-23 Alder Biopharmaceuticals, Inc. Anbauverfahren zum erhalten einer klonpopulation von antigenspezifischen b-zellen
GB0619291D0 (en) 2006-09-29 2006-11-08 Ucb Sa Altered antibodies
US9156914B2 (en) 2006-12-19 2015-10-13 Ablynx N.V. Amino acid sequences directed against a metalloproteinase from the ADAM family and polypeptides comprising the same for the treatment of ADAM-related diseases and disorders
AU2007336242B2 (en) 2006-12-19 2012-08-30 Ablynx N.V. Amino acid sequences directed against GPCRs and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders
US9512236B2 (en) 2006-12-19 2016-12-06 Ablynx N.V. Amino acid sequences directed against GPCRS and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders
CA2706425A1 (en) 2007-11-27 2009-06-04 Ablynx N.V. Method for obtaining polypeptide constructs comprising two or more single domain antibodies
US8557965B2 (en) 2008-04-07 2013-10-15 Ablynx N.V. Single variable domains against notch pathway members
US9212226B2 (en) 2008-05-16 2015-12-15 Ablynx N.V. Amino acid sequences directed against CXCR4 and other GPCRs and compounds comprising the same
LT2285408T (lt) 2008-06-05 2019-01-25 Ablynx N.V. Aminorūgščių sekos, nukreiptos prieš viruso apvalkalo baltymus, ir tokias sekas turintys polipeptidai, skirti virusinių ligų gydymui
CA2747644C (en) 2008-12-19 2023-01-24 Ablynx N.V. Method for generation of immunoglobulin sequences
GB0903207D0 (en) 2009-02-25 2009-04-08 Ucb Pharma Sa Method for expressing multimeric proteins
WO2010097435A1 (en) 2009-02-25 2010-09-02 Ucb Pharma, S.A. Method for producing antibodies
WO2011063454A1 (en) * 2009-11-24 2011-06-03 Biassex Pty Ltd Method for influencing sex selection ' in artificial insemination and apparatus for same
US20120321640A1 (en) 2009-12-01 2012-12-20 Ablynx N.V. Von willebrand factor specific binding agents and uses thereof
HRP20251657T1 (hr) 2009-12-14 2026-02-13 Ablynx N.V. Imunoglobulinska protutijela s jednostrukom varijabilnom domenom protiv ox40l, konstrukti i njihova terapijska upotreba
US9120855B2 (en) 2010-02-10 2015-09-01 Novartis Ag Biologic compounds directed against death receptor 5
EP2552962B1 (de) 2010-03-26 2016-03-23 Ablynx N.V. Einzelne, gegen cxcr7 gerichtete variable immunoglobulindomänen
US9932403B2 (en) 2010-05-20 2018-04-03 Ablynx Nv Biological materials related to HER3
PY1147875A (es) 2010-11-08 2015-08-03 Novartis Ag Polipéptidos de enlace de los receptores de quimiocina
AU2012234284B2 (en) 2011-03-28 2015-10-08 Ablynx Nv Bispecific anti-CXCR7 immunoglobulin single variable domains
UA117218C2 (uk) 2011-05-05 2018-07-10 Мерк Патент Гмбх Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
US9328174B2 (en) 2012-05-09 2016-05-03 Novartis Ag Chemokine receptor binding polypeptides
WO2014093786A1 (en) * 2012-12-14 2014-06-19 Abbvie, Inc. Methods for increasing the efficiency of hybridoma generation
WO2014105006A1 (en) * 2012-12-24 2014-07-03 Sorrento Therapeutics, Inc. Pharmaceutical composition of recombinant polyclonal immunoglobulins
US20160075766A1 (en) * 2013-05-21 2016-03-17 Roche Diagnostics Operations, Inc. Method for producing antibodies using ovine b-cells and uses thereof
JP6568207B2 (ja) * 2014-05-19 2019-08-28 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ヒツジｂ細胞を用いて抗体を産生するための方法およびその使用
EP4294834A2 (de) 2021-02-19 2023-12-27 The United States of America, as represented by The Secretary, Department of Health and Human Services Einzeldomänenantikörper zur neutralisierung von sars-cov-2
US20260103529A1 (en) 2022-10-18 2026-04-16 Confo Therapeutics N.V. Amino Acid Sequences Directed Against the Melanocortin 4 Receptor and Polypeptides Comprising the Same for the Treatment of MC4R-Related Diseases and Disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2090126C (en) 1990-08-02 2002-10-22 John W. Schrader Methods for the production of proteins with a desired function
US5256542A (en) * 1992-03-09 1993-10-26 Tanox Biosystems, Inc. Selecting low frequency antigen-specific single B lymphocytes with correction for background noise
US5213960A (en) * 1992-03-09 1993-05-25 Tanox Biosystems, Inc. Methods for selecting low frequency antigen-specific single B lymphocytes
AU679949B2 (en) * 1992-10-21 1997-07-17 Stefan Miltenyi Direct selection of cells by secretion product
GB0118337D0 (en) * 2001-07-27 2001-09-19 Lonza Biologics Plc Method for selecting antibody expressing cells
WO2004051268A1 (en) * 2002-12-03 2004-06-17 Celltech R & D Limited Assay for identifying antibody producing cells

Also Published As

Publication number Publication date
US20090275056A1 (en) 2009-11-05
US8304200B2 (en) 2012-11-06
US20060263353A1 (en) 2006-11-23
EP1658500A1 (de) 2006-05-24
ES2385829T3 (es) 2012-08-01
WO2005019824A1 (en) 2005-03-03
EP1658500B1 (de) 2012-04-18

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